sporidesmin E (BioDeep_00000284952)

   

natural product


代谢物信息卡片


sporidesmin E

化学式: C18H20ClN3O6S3 (505.0202730000001)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COc1c(Cl)cc2c(c1OC)N(C)C1N3C(=O)C4(C)SSSC3(C(=O)N4C)C(O)C21O
InChI:

描述信息

同义名列表

1 个代谢物同义名

sporidesmin E



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

14 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • J S Munday, A Ridler, D Aberdein, N A Thomson, K Griffiths. Chronic facial eczema in sheep: description of gross and histological changes in the liver and association with serum gamma-glutamyltransferase activity at the time of sporidesmin intoxication. New Zealand veterinary journal. 2021 Mar; 69(2):104-112. doi: 10.1080/00480169.2020.1823904. [PMID: 32981484]
  • G C Lindsay, C A Morris, M Boucher, K Capundan, T W Jordan. Effects of sporidesmin on cultured biliary tract cells from Romney lambs that differed in their sensitivity to sporidesmin. New Zealand veterinary journal. 2018 Nov; 66(6):325-331. doi: 10.1080/00480169.2018.1515676. [PMID: 30145942]
  • E L Cuttance, M A Stevenson, R A Laven, W A Mason. Facial eczema management protocols used on dairy farms in the North Island of New Zealand and associated concentrations of zinc in serum. New Zealand veterinary journal. 2016 Nov; 64(6):343-50. doi: 10.1080/00480169.2016.1220846. [PMID: 27498721]
  • W D Hohenboken, J L Robertson, D J Blodgett, C A Morris, N R Towers. Sporidesmin-induced mortality and histological lesions in mouse lines divergently selected for response to toxins in endophyte-infected fescue. Journal of animal science. 2000 Aug; 78(8):2157-63. doi: 10.2527/2000.7882157x. [PMID: 10947103]
  • G C Upreti, M K Jain. Interaction of sporidesmin, a mycotoxin from Pithomyces chartarum, with lipid bilayers. Bioscience reports. 1993 Aug; 13(4):233-43. doi: 10.1007/bf01123505. [PMID: 8305634]
  • B L Smith, C O Miles. A role for Brachiaria decumbens in hepatogenous photosensitization of ruminants?. Veterinary and human toxicology. 1993 Jun; 35(3):256-7. doi: ". [PMID: 8351801]
  • C H Mullenax. Brachiaria decumbens toxicity--grass or fungus?. Veterinary and human toxicology. 1991 Oct; 33(5):464-5. doi: ". [PMID: 1746138]
  • T W Jordan. Use of indirect immunofluorescence to show changes in liver actin microfilament staining in inbred mice strains exposed to the mycotoxin sporidesmin. Liver. 1986 Apr; 6(2):78-84. doi: 10.1111/j.1600-0676.1986.tb00272.x. [PMID: 3526071]
  • J P Braun, P Bézille, A G Rico. [Biochemical semiology of the liver in ruminants]. Reproduction, nutrition, developpement. 1986; 26(1B):227-43. doi: . [PMID: 2871602]
  • S J Cordiner, T W Jordan. Inhibition by sporidesmin of hepatocyte bile acid transport. The Biochemical journal. 1983 Apr; 212(1):197-204. doi: 10.1042/bj2120197. [PMID: 6870851]
  • J A PETERS. MECHANISM OF EARLY SPORIDESMIN INTOXICATION IN SHEEP. Nature. 1963 Oct; 200(?):286. doi: 10.1038/200286a0. [PMID: 14081089]