Destruxin B (BioDeep_00000284358)
代谢物信息卡片
化学式: C30H51N5O7 (593.3788296)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC(C)C1C(=O)N(C(C(=O)N(C(C(=O)NCCC(=O)OC(C(=O)N2CCCC2C(=O)N1)CC(C)C)C)C)C(C)C)C
InChI: InChI=1S/C30H51N5O7/c1-10-19(6)24-29(40)34(9)25(18(4)5)30(41)33(8)20(7)26(37)31-14-13-23(36)42-22(16-17(2)3)28(39)35-15-11-12-21(35)27(38)32-24/h17-22,24-25H,10-16H2,1-9H3,(H,31,37)(H,32,38)
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:181259
- PubChem: 428373
- ChEMBL: CHEMBL1736621
- CAS: 2503-26-6
- PMhub: MS000036233
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Cong Dong, Jiuru Yu, Ying Zhu, Changjin Dong. Inhibition of hepatitis B virus gene expression & replication by crude destruxins from Metarhizium anisopliae var. dcjhyium.
The Indian journal of medical research.
2013 Dec; 138(6):969-76. doi:
NULL
. [PMID: 24521644] - M Soledade C Pedras, Iman Khallaf. Molecular interactions of the phytotoxins destruxin B and sirodesmin PL with crucifers and cereals: metabolism and elicitation of plant defenses.
Phytochemistry.
2012 May; 77(?):129-39. doi:
10.1016/j.phytochem.2012.02.010
. [PMID: 22414311] - Bing Wang, Qianjin Kang, Yuzhen Lu, Linquan Bai, Chengshu Wang. Unveiling the biosynthetic puzzle of destruxins in Metarhizium species.
Proceedings of the National Academy of Sciences of the United States of America.
2012 Jan; 109(4):1287-92. doi:
10.1073/pnas.1115983109
. [PMID: 22232661] - M S C Pedras, S Montaut, I L Zaharia, Y Gai, D E Ward. Transformation of the host-selective toxin destruxin B by wild crucifers: probing a detoxification pathway.
Phytochemistry.
2003 Nov; 64(5):957-63. doi:
10.1016/s0031-9422(03)00444-8
. [PMID: 14561511] - Chengshu Wang, Anke Skrobek, Tariq M Butt. Concurrence of losing a chromosome and the ability to produce destruxins in a mutant of Metarhizium anisopliae.
FEMS microbiology letters.
2003 Sep; 226(2):373-8. doi:
10.1016/s0378-1097(03)00640-2
. [PMID: 14553935] - M Soledade C Pedras, L Irina Zaharia, Dale E Ward. The destruxins: synthesis, biosynthesis, biotransformation, and biological activity.
Phytochemistry.
2002 Mar; 59(6):579-96. doi:
10.1016/s0031-9422(02)00016-x
. [PMID: 11867090] - Abha Khandelwal, Anil Kumar, Manish Banerjee, G K Garg. Effect of alternaria pathotoxin(s) on expression of p53-like apoptotic protein in calli and leaves of Brassica campestris.
Indian journal of experimental biology.
2002 Jan; 40(1):89-94. doi:
"
. [PMID: 12561976] - D E Ward, Y Gai, R Lazny, M S Pedras. Probing host-selective phytotoxicity: synthesis of destruxin B and several natural analogues.
The Journal of organic chemistry.
2001 Nov; 66(23):7832-40. doi:
10.1021/jo015953+
. [PMID: 11701043] - A R Bandani, B Amiri, T M Butt, R Gordon-Weeks. Effects of efrapeptin and destruxin, metabolites of entomogenous fungi, on the hydrolytic activity of a vacuolar type ATPase identified on the brush border membrane vesicles of Galleria mellonella midgut and on plant membrane bound hydrolytic enzymes.
Biochimica et biophysica acta.
2001 Feb; 1510(1-2):367-77. doi:
10.1016/s0005-2736(00)00370-9
. [PMID: 11342173] - M S Pedras, I L Zaharia, Y Gai, Y Zhou, D E Ward. In planta sequential hydroxylation and glycosylation of a fungal phytotoxin: Avoiding cell death and overcoming the fungal invader.
Proceedings of the National Academy of Sciences of the United States of America.
2001 Jan; 98(2):747-52. doi:
10.1073/pnas.98.2.747
. [PMID: 11149945] - A Niemann, A Takatsuki, H P Elsässer. The lysosomotropic agent monodansylcadaverine also acts as a solvent polarity probe.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
2000 Feb; 48(2):251-8. doi:
10.1177/002215540004800210
. [PMID: 10639491] - A Tsunoo, M Kamijo. Non-cyclic AMP-dependent, positive inotropic cyclodepsipeptides with negative chronotropy.
The Journal of pharmacology and experimental therapeutics.
1999 Sep; 290(3):1006-12. doi:
. [PMID: 10454471]
- H C Chen, C K Chou, C M Sun, S F Yeh. Suppressive effects of destruxin B on hepatitis B virus surface antigen gene expression in human hepatoma cells.
Antiviral research.
1997 May; 34(3):137-44. doi:
10.1016/s0166-3542(97)01031-0
. [PMID: 9191021]