3-Sialyl Lewis (BioDeep_00000028239)
human metabolite Endogenous
代谢物信息卡片
(2S,4S,5R,6R)-2-{[(2R,3R,4S,5S,6R)-2-{[(2R,3R,4R,5R)-5,6-dihydroxy-2-[(1-hydroxyethylidene)amino]-1-oxo-4-{[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}hexan-3-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-4-hydroxy-5-[(1-hydroxyethylidene)amino]-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate
化学式: C31H52N2O23 (820.2961)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1C(C(C(C(O1)OC(C(CO)O)C(C(C=O)NC(=O)C)OC2C(C(C(C(O2)CO)O)OC3(CC(C(C(O3)C(C(CO)O)O)NC(=O)C)O)C(=O)O)O)O)O)O
InChI: InChI=1S/C31H52N2O23/c1-9-18(43)21(46)22(47)28(51-9)54-25(15(42)7-36)24(12(5-34)32-10(2)38)53-29-23(48)27(20(45)16(8-37)52-29)56-31(30(49)50)4-13(40)17(33-11(3)39)26(55-31)19(44)14(41)6-35/h5,9,12-29,35-37,40-48H,4,6-8H2,1-3H3,(H,32,38)(H,33,39)(H,49,50)/t9-,12-,13-,14+,15+,16+,17+,18+,19+,20-,21+,22-,23+,24+,25+,26+,27-,28-,29-,31-/m0/s1
描述信息
3-Sialyl Lewis tetrasaccharide, is a tumor-associated carbohydrate antigen. It is used as a tumor marker in colon and pancreatic cancer. When the selectin family of adhesion molecules was described, it was found that 3-Sialyl Lewis, along with sialyl Lewis(x) antigen, is a ligand for E-selectin, responsible for adhesion of several types of human carcinoma cells to endothelium. It has been suggested that such interactions play an important role in the formation of metastases by colon and pancreatic cancer cells. (PMID:12362971) [HMDB]
3-Sialyl Lewis tetrasaccharide, is a tumor-associated carbohydrate antigen. It is used as a tumor marker in colon and pancreatic cancer. When the selectin family of adhesion molecules was described, it was found that 3-Sialyl Lewis, along with sialyl Lewis(x) antigen, is a ligand for E-selectin, responsible for adhesion of several types of human carcinoma cells to endothelium. It has been suggested that such interactions play an important role in the formation of metastases by colon and pancreatic cancer cells. (PMID:12362971).
C307 - Biological Agent > C268 - Antigen > C912 - Tumor Antigen
同义名列表
10 个代谢物同义名
(2S,4S,5R,6R)-2-{[(2R,3R,4S,5S,6R)-2-{[(2R,3R,4R,5R)-5,6-dihydroxy-2-[(1-hydroxyethylidene)amino]-1-oxo-4-{[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}hexan-3-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-4-hydroxy-5-[(1-hydroxyethylidene)amino]-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate; (2S,4S,5R,6R)-5-acetamido-2-{[(2R,3R,4S,5S,6R)-2-{[(2R,3R,4R,5R)-2-acetamido-5,6-dihydroxy-1-oxo-4-{[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}hexan-3-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid; O-(N-Acetyl-alpha-neuraminosyl)-(2->3)-O-beta-delta-galactopyranosyl-(1->3)-O-[6-deoxy-alpha-L-galactopyranosyl-(1->4)]-2-(acetylamino)-2-deoxy- D-glucose; O-(N-Acetyl-alpha-neuraminosyl)-(2->3)-O-beta-D-galactopyranosyl-(1->3)-O-[6-deoxy-alpha-L-galactopyranosyl-(1->4)]-2-(acetylamino)-2-deoxy- D-glucose; 3-Sialyl lewis a; 3-Sialyl Lewis; sialyl-lewis A; Sialyl lea tri; Sialyl lewis a; SLea
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:185147
- PubChem: 643993
- HMDB: HMDB0006579
- MeSH: CA-19-9 Antigen
- foodb: FDB023981
- chemspider: 559075
- CAS: 92448-22-1
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
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Journal of translational medicine.
2024 Feb; 22(1):184. doi:
10.1186/s12967-024-04989-z. [PMID: 38378604] - Chenzheng Gu, Anquan Shang, Gege Liu, Jichao Zhu, Wei Zhang, Limin Jin, Zujun Sun, Dong Li. Identification of CD147-positive extracellular vesicles as novel non-invasive biomarkers for the diagnosis and prognosis of colorectal cancer.
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Gastroenterology.
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World journal of gastroenterology.
2023 Jan; 29(4):706-730. doi:
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Annals of medicine.
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World journal of surgical oncology.
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Medicine.
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2022 Jul; 27(7):1212-1221. doi:
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Surgery.
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Gut.
2022 07; 71(7):1359-1372. doi:
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Journal of clinical laboratory analysis.
2022 Jun; 36(6):e24447. doi:
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Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].
2022 Jun; 22(5):626-635. doi:
10.1016/j.pan.2022.04.010. [PMID: 35613957] - Shuqiao Yang, Xi Zhan, Jing Wang, Yali Fan, Ruimin Ma, Qiao Ye. Serum Oncomarkers in Patients with MPO-ANCA-Positive Vasculitis: Diagnostic and Prognostic Predictive Values for Interstitial Lung Disease.
Lung.
2022 06; 200(3):331-338. doi:
10.1007/s00408-022-00532-3. [PMID: 35426513] - Hong Zou, Shu-Han Liu, Rong Yang, Xue-Jing Wu, Ying-Ping Cao, Hui-Fang Huang. Combination of Neutrophil-to-Lymphocyte Ratio and Red Cell Distribution Width With Serum Tumor Markers for the Differential Diagnosis of Breast Cancer and its Association With Pathological Features and Molecular Types.
Clinical breast cancer.
2022 06; 22(4):e526-e535. doi:
10.1016/j.clbc.2021.11.014. [PMID: 34963613] - Satoshi Matsui, Yusuke Yamamoto, Yukiyasu Okamura, Takaaki Ito, Ryo Ashida, Katsuhisa Ohgi, Mihoko Yamada, Shimpei Otsuka, Katsuhiko Uesaka, Teiichi Sugiura. The Prognostic Relevance of Preoperative CEA and CA19-9 for Ampulla of Vater Carcinoma.
Anticancer research.
2022 Jun; 42(6):3169-3176. doi:
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The Journal of surgical research.
2022 06; 274(?):68-76. doi:
10.1016/j.jss.2022.01.001. [PMID: 35123285] - Mengchen Shi, Yu Tian, Lingyuan He, Jingdan Zhang, Xiangling Yang, Huanliang Liu. Potential roles of serum ATPase and AMPase in predicting diagnosis of colorectal cancer patients.
Bioengineered.
2022 06; 13(6):14204-14214. doi:
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Journal of hepatology.
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BMC cancer.
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Mikrochimica acta.
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2022 03; 150(5):881-894. doi:
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The International journal of biological markers.
2022 Mar; 37(1):81-89. doi:
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Neoplasma.
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Clinical and translational gastroenterology.
2022 02; 13(3):e00468. doi:
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Journal of the National Cancer Institute.
2022 02; 114(2):228-234. doi:
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Cellular and molecular biology (Noisy-le-Grand, France).
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Bioscience trends.
2022 Jan; 15(6):397-405. doi:
10.5582/bst.2021.01517. [PMID: 34880159] - Denise Wolrab, Robert Jirásko, Eva Cífková, Marcus Höring, Ding Mei, Michaela Chocholoušková, Ondřej Peterka, Jakub Idkowiak, Tereza Hrnčiarová, Ladislav Kuchař, Robert Ahrends, Radana Brumarová, David Friedecký, Gabriel Vivo-Truyols, Pavel Škrha, Jan Škrha, Radek Kučera, Bohuslav Melichar, Gerhard Liebisch, Ralph Burkhardt, Markus R Wenk, Amaury Cazenave-Gassiot, Petr Karásek, Ivo Novotný, Kristína Greplová, Roman Hrstka, Michal Holčapek. Lipidomic profiling of human serum enables detection of pancreatic cancer.
Nature communications.
2022 01; 13(1):124. doi:
10.1038/s41467-021-27765-9. [PMID: 35013261] - Neus Martínez-Bosch, Helena Cristóbal, Mar Iglesias, Meritxell Gironella, Luis Barranco, Laura Visa, Domenico Calafato, Silvia Jiménez-Parrado, Julie Earl, Alfredo Carrato, Noemí Manero-Rupérez, Mireia Moreno, Albert Morales, Carmen Guerra, Pilar Navarro, Pablo García de Frutos. Soluble AXL is a novel blood marker for early detection of pancreatic ductal adenocarcinoma and differential diagnosis from chronic pancreatitis.
EBioMedicine.
2022 Jan; 75(?):103797. doi:
10.1016/j.ebiom.2021.103797. [PMID: 34973624] - Pingxia Lu, Xianjin Zhu, Yanfang Song, Yue Luo, Junsheng Lin, Junrong Zhang, Yingping Cao, Zhengyuan Huang. Methylated Septin 9 as a Promising Biomarker in the Diagnosis and Recurrence Monitoring of Colorectal Cancer.
Disease markers.
2022; 2022(?):7087885. doi:
10.1155/2022/7087885. [PMID: 35818587] - Zhengyuan Huang, Zhaozhong Li, Xianqiang Chen, Xianjin Zhu, Junrong Zhang, Yanfang Song, Yingping Cao, Pingxia Lu. Comparison between Clinical Utility of CXCL-8 and Clinical Practice Tumor Markers for Colorectal Cancer Diagnosis.
BioMed research international.
2022; 2022(?):1213968. doi:
10.1155/2022/1213968. [PMID: 36567905] - Violetta Rosiek, Monika Wójcik-Giertuga, Beata Kos-Kudła. Serum tumor markers for detection of bone metastases in patients with lung neuroendocrine neoplasms'.
Cancer treatment and research communications.
2022; 31(?):100533. doi:
10.1016/j.ctarc.2022.100533. [PMID: 35202905] - Jianqi Yang, Wenmiao Cao, Enming Xing. Levels and Significance of Tumor Markers and Cytokines in Serum and Peritoneal Lavage Fluid of Patients with Peritoneal Metastasis of Gastric Cancer.
BioMed research international.
2022; 2022(?):9528444. doi:
10.1155/2022/9528444. [PMID: 35692594] - Márton Benke, Nelli Farkas, Péter Hegyi, Benedek Tinusz, Patrícia Sarlós, Bálint Erőss, Kata Szemes, Nóra Vörhendi, Zsolt Szakács, Ákos Szücs. Preoperative Serum Carbohydrate Antigen 19-9 Levels Cannot Predict the Surgical Resectability of Pancreatic Cancer: A Meta-Analysis.
Pathology oncology research : POR.
2022; 28(?):1610266. doi:
10.3389/pore.2022.1610266. [PMID: 35645620] - Yasuhiro Murata, Toru Ogura, Aoi Hayasaki, Kazuyuki Gyoten, Takahiro Ito, Yusuke Iizawa, Takehiro Fujii, Akihiro Tanemura, Naohisa Kuriyama, Masashi Kishiwada, Hiroyuki Sakurai, Shugo Mizuno. Predictive risk factors for early recurrence in patients with localized pancreatic ductal adenocarcinoma who underwent curative-intent resection after preoperative chemoradiotherapy.
PloS one.
2022; 17(4):e0264573. doi:
10.1371/journal.pone.0264573. [PMID: 35377885] - Shun Zhang, Jing-Ze Li, Tao Du, Hai-Qiang Li, Ren-Hao Hu, Chi-Ye Ma, Xi-Mao Cui, Chun Song, Xiao-Hua Jiang. The Modified Glasgow Prognostic Score Predicts Survival in Gastric Cancer Patients with Normal CEA and CA19-9.
Canadian journal of gastroenterology & hepatology.
2022; 2022(?):3953004. doi:
10.1155/2022/3953004. [PMID: 35734015] - Min Woo Kim, Hani Koh, Jee Ye Kim, Suji Lee, Hyojung Lee, Young Kim, Ho Kyoung Hwang, Seung Il Kim. Tumor-Specific miRNA Signatures in Combination with CA19-9 for Liquid Biopsy-Based Detection of PDAC.
International journal of molecular sciences.
2021 Dec; 22(24):. doi:
10.3390/ijms222413621. [PMID: 34948417] - Bikal Ghimire, Prasan Bir Singh Kansakar, Yogendra Prasad Sngh. Comparison of serum biomarkers cifra 21-1 and ca 19-9 in biliary tract cancers.
Journal of Nepal Health Research Council.
2021 Dec; 19(3):626-630. doi:
10.33314/jnhrc.v19i3.2044. [PMID: 35140443] - Ming Yang, Chun-Ye Zhang. Diagnostic biomarkers for pancreatic cancer: An update.
World journal of gastroenterology.
2021 Dec; 27(45):7862-7865. doi:
10.3748/wjg.v27.i45.7862. [PMID: 34963749] - Min Jung Lee, Keun Na, Heon Shin, Chae-Yeon Kim, Jin-Young Cho, Chang Moo Kang, Sung Hyun Kim, Hoguen Kim, Hye Jin Choi, Choong-Kun Lee, Sumi Bae, Sunghwa Son, Young-Ki Paik. Early Diagnostic Ability of Human Complement Factor B in Pancreatic Cancer Is Partly Linked to Its Potential Tumor-Promoting Role.
Journal of proteome research.
2021 12; 20(12):5315-5328. doi:
10.1021/acs.jproteome.1c00805. [PMID: 34766501] - Zhenxing Liang, Huashan Liu, Yunfeng Zhang, Li Xiong, Ziwei Zeng, Xiaowen He, Fengwei Wang, Xianrui Wu, Ping Lan. Cyr61 from adipose-derived stem cells promotes colorectal cancer metastasis and vasculogenic mimicry formation via integrin αV β5.
Molecular oncology.
2021 12; 15(12):3447-3467. doi:
10.1002/1878-0261.12998. [PMID: 33999512] - Yasuhiro Murata, Shugo Mizuno, Masashi Kishiwada, Katsunori Uchida, Daisuke Noguchi, Kazuyuki Gyoten, Aoi Hayasaki, Takehiro Fujii, Yusuke Iizawa, Akihiro Tanemura, Naohisa Kuriyama, Hiroyuki Sakurai, Shuji Isaji. Clinical significance and predictors of complete or near-complete histological response to preoperative chemoradiotherapy in patients with localized pancreatic ductal adenocarcinoma.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].
2021 Dec; 21(8):1482-1490. doi:
10.1016/j.pan.2021.08.011. [PMID: 34452821] - Jiamin Jiang, Hongmei Liu, Xiuting Li, Ying Chen, Chenjie Gu, Guodong Wei, Jun Zhou, Tao Jiang. Nonmetallic SERS-based immunosensor byintegrating MoS2 nanoflower and nanosheet towards the direct serum detection of carbohydrate antigen 19-9.
Biosensors & bioelectronics.
2021 Dec; 193(?):113481. doi:
10.1016/j.bios.2021.113481. [PMID: 34252705] - Xiaoling Zhuge, Hao Zhou, Liming Chen, Hui Chen, Xiao Chen, Chuangen Guo. The association between serum ferritin levels and malignant intraductal papillary mucinous neoplasms.
BMC cancer.
2021 Nov; 21(1):1253. doi:
10.1186/s12885-021-08986-z. [PMID: 34800987] - Hyeong Seok Kim, Youngmin Han, Jae Seung Kang, Yoon Hyung Kang, Mirang Lee, Hee Ju Sohn, Hongbeom Kim, Wooil Kwon, Jin-Young Jang. Serum carcinoembryonic antigen and carbohydrate antigen 19-9 as preoperative diagnostic biomarkers of extrahepatic bile duct cancer.
BJS open.
2021 11; 5(6):. doi:
10.1093/bjsopen/zrab127. [PMID: 34935900] - Tongmei Duan, Xun Chen, Jing Wu, Ronghai Li, Huijuan Guo, Juan Du, Jie Guo. Serum carbohydrate antigen 72-4 concentrations decrease with age in females but not in males in Beijing, China.
Annals of clinical biochemistry.
2021 11; 58(6):556-562. doi:
10.1177/00045632211026961. [PMID: 34120477] - Quan Chen, Qijue Lu, Xiang Fei, Chunguang Li, Bai Li. Elevated tumor markers in a benign lung disease.
Journal of cardiothoracic surgery.
2021 Oct; 16(1):308. doi:
10.1186/s13019-021-01688-4. [PMID: 34663400] - Lili Chen, Yizhen Niu, Xiaoyun Wan, Lina Yu, Xiaofei Zhang, Amanda Louise Strickland, Liya Dong, Feng Zhou, Weiguo Lu. Clinicopathological features and outcomes in gastric-type of HPV-independent endocervical adenocarcinomas.
BMC cancer.
2021 Oct; 21(1):1095. doi:
10.1186/s12885-021-08792-7. [PMID: 34635081] - T Liu, X Li, D Liu, S Liu, M Dong. Increased serum CA125 II, but not CEA，CA19-9，AFP or CA72-4 in colon cancer compared to rectal cancer.
British journal of biomedical science.
2021 Oct; 78(4):218-220. doi:
10.1080/09674845.2020.1868685. [PMID: 33393429] - Alina Tanţău, Daniel-Corneliu Leucuţa, Marcel Tanţău, Emil Boţan, Roxana Zaharie, Alina Mândruţiu, Ionuţ-Ciprian Tomuleasa. Inflammation, Tumoral Markers and Interleukin-17, -10, and -6 Profiles in Pancreatic Adenocarcinoma and Chronic Pancreatitis.
Digestive diseases and sciences.
2021 10; 66(10):3427-3438. doi:
10.1007/s10620-020-06700-w. [PMID: 33184795] - Kelly E Henry, Travis M Shaffer, Kyeara N Mack, Janine Ring, Anuja Ogirala, Susanne Klein-Scory, Christina Eilert-Micus, Wolff Schmiegel, Thilo Bracht, Barbara Sitek, Marguerite Clyne, Colm J Reid, Bence Sipos, Jason S Lewis, Holger Kalthoff, Jan Grimm. Exploiting the MUC5AC Antigen for Noninvasive Identification of Pancreatic Cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2021 10; 62(10):1384-1390. doi:
10.2967/jnumed.120.256776. [PMID: 33712530] - Wael Mahmoud Aboulthana, Wafaa Ghoneim Shousha, Ehab Abdel-Raouf Essawy, Mahmoud Hosny Saleh, Alaa Hamed Salama. Assessment of the Anti-Cancer Efficiency of Silver Moringa oleifera Leaves Nano-extract against Colon Cancer Induced Chemically in Rats.
Asian Pacific journal of cancer prevention : APJCP.
2021 Oct; 22(10):3267-3286. doi:
10.31557/apjcp.2021.22.10.3267. [PMID: 34711004] - Yunus Emre Purut, Burak Giray, Esra Gurbuz. Effect of the coronavirus pandemic on tumor markers.
Journal of medical virology.
2021 Sep; 93(9):5405-5408. doi:
10.1002/jmv.27057. [PMID: 33932304] - Yanfang Cui, Shaohua Shi, Shaoqin Zhang, Chunyan Huang, Peng Li, Chao Han. Application value of Doppler ultrasound combined with CA125 and CA19.9 in the early diagnosis of epithelial ovarian cancer.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology.
2021 Sep; 26(5):1802-1808. doi:
NULL. [PMID: 34761586] - Francesco Santoro, Tecla Zimotti, Adriana Mallardi, Alessandra Leopizzi, Enrica Vitale, Nicola Tarantino, Armando Ferraretti, Antonio Giovanni Solimando, Vito Racanelli, Massimo Iacoviello, Michele Cannone, Matteo Di Biase, Natale Daniele Brunetti. Prognostic role of neoplastic markers in Takotsubo syndrome.
Scientific reports.
2021 08; 11(1):16548. doi:
10.1038/s41598-021-95990-9. [PMID: 34400692] - Zozan Guleken, Huri Bulut, Güldal İnal Gültekin, Soykan Arıkan, İlhan Yaylım, Mehmet Tolgahan Hakan, Dilara Sönmez, Nevzat Tarhan, Joanna Depciuch. Assessment of structural protein expression by FTIR and biochemical assays as biomarkers of metabolites response in gastric and colon cancer.
Talanta.
2021 Aug; 231(?):122353. doi:
10.1016/j.talanta.2021.122353. [PMID: 33965021] - Dongdong Yu, Jun Sun, Yu Weng, Liang Luo, Jinghao Sheng, Zhengping Xu. Serum angiogenin as a potential biomarker for early detection of colorectal adenomas and colorectal cancer.
Anti-cancer drugs.
2021 08; 32(7):703-708. doi:
10.1097/cad.0000000000001047. [PMID: 33661188] - Limei Cui, Naqiang Lv, Bin Li, Jing Tao, Xiaomin Zheng, Yehua Yan, Cuiping Liu. Serum CA 19-9 Level is Correlated to the Clinical Characteristics and Chronic Complications of Patients Newly Diagnosed with Type 2 Diabetes Mellitus.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.
2021 Aug; 129(8):581-586. doi:
10.1055/a-0994-9970. [PMID: 31461764] - Masaya Yamanaka, Masamichi Hayashi, Suguru Yamada, Fuminori Sonohara, Hideki Takami, Yoshikuni Inokawa, Dai Shimizu, Norifumi Hattori, Mitsuro Kanda, Chie Tanaka, Goro Nakayama, Masahiko Koike, Yasuhiro Kodera. A Possible Definition of Oligometastasis in Pancreatic Cancer and Associated Survival Outcomes.
Anticancer research.
2021 Aug; 41(8):3933-3940. doi:
10.21873/anticanres.15189. [PMID: 34281856] - Yasuhiko Hamada, Kyosuke Tanaka, Norihiko Yamamoto. A Middle-Aged Woman with Elevated Serum CA19-9 and Lymphadenopathy.
The American journal of medicine.
2021 08; 134(8):e459-e460. doi:
10.1016/j.amjmed.2021.02.030. [PMID: 33812860] - Robert S O'Neill, Alina Stoita. Biomarkers in the diagnosis of pancreatic cancer: Are we closer to finding the golden ticket?.
World journal of gastroenterology.
2021 Jul; 27(26):4045-4087. doi:
10.3748/wjg.v27.i26.4045. [PMID: 34326612] - Hui Zhang, Lei Jia, Youqing Xu. Etiologies of remarkably elevated serum levels of carbohydrate antigen 19-9.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology.
2021 Jul; 26(4):1653-1658. doi:
NULL. [PMID: 34565032] - Xavier Bosch, Rafael Molina, Ramon Marrades, Josep M Augé, Martina Pellicé, Alfonso López-Soto. Tumour markers with clinically controlled cut-offs for suspected cancer.
European journal of clinical investigation.
2021 Jul; 51(7):e13523. doi:
10.1111/eci.13523. [PMID: 33594702] - He Cheng, Guopei Luo, Kaizhou Jin, Zhiwen Xiao, Yunzhen Qian, Yitao Gong, Xianjun Yu, Chen Liu. Predictive Values of Preoperative Markers for Resectable Pancreatic Body and Tail Cancer Determined by MDCT to Detect Occult Metastases.
World journal of surgery.
2021 07; 45(7):2185-2190. doi:
10.1007/s00268-021-06047-x. [PMID: 33774691] - Rachel L Dittmar, Suyu Liu, Mei Chee Tai, Kimal Rajapakshe, Ying Huang, Gary Longton, Christine DeCapite, Mark W Hurd, Pamela L Paris, Kimberly S Kirkwood, Cristian Coarfa, Anirban Maitra, Randall E Brand, Ann M Killary, Subrata Sen. Plasma miRNA Biomarkers in Limited Volume Samples for Detection of Early-stage Pancreatic Cancer.
Cancer prevention research (Philadelphia, Pa.).
2021 07; 14(7):729-740. doi:
10.1158/1940-6207.capr-20-0303. [PMID: 33893071] - Weigen Wu, Xiaoping Xia, Chen Cheng, Lili Niu, Jianguo Wu, Yun Qian. Serum Soluble PD-L1, PD-L2, and B7-H5 as Potential Diagnostic Biomarkers of Human Pancreatic Cancer.
Clinical laboratory.
2021 Jun; 67(6):. doi:
10.7754/clin.lab.2021.210103. [PMID: 34107622] - Tao Yu, Linfeng Shu, Youxiang Chen, Yong Zhu, Nonghua Lu, Yongkang Lai, Tao Huang, Xu Shu. Diagnosis of malignant versus tuberculous ascites using tumor markers and globulin ratios in serum and ascites: A Fisher discriminant model.
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology.
2021 Jun; 22(2):93-98. doi:
10.1016/j.ajg.2021.05.002. [PMID: 34090828] - Marin Strijker, Eran van Veldhuisen, Lydia G van der Geest, Olivier R Busch, Maarten F Bijlsma, Nadia Haj Mohammad, Marjolein Y Homs, Jeanin E van Hooft, Joanne Verheij, Judith de Vos-Geelen, Johanna W Wilmink, W Ewout W Steyerberg, Marc G Besselink, Hanneke W van Laarhoven. Readily available biomarkers predict poor survival in metastatic pancreatic cancer.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2021 Jun; 26(4):325-334. doi:
10.1080/1354750x.2021.1893814. [PMID: 33663300] - Hsueh-Yao Chu, Chih-Yung Yang, Ping-Hao Yeh, Chun-Jieh Hsu, Lu-Wei Chang, Wei-Jen Chan, Chien-Ping Lin, You-You Lyu, Wei-Cheng Wu, Chun-Wei Lee, Jen-Kuei Wu, Jeng-Kai Jiang, Fan-Gang Tseng. Highly Correlated Recurrence Prognosis in Patients with Metastatic Colorectal Cancer by Synergistic Consideration of Circulating Tumor Cells/Microemboli and Tumor Markers CEA/CA19-9.
Cells.
2021 05; 10(5):. doi:
10.3390/cells10051149. [PMID: 34068719] - Xiwen Huang, Yongquan Lan, En Li, Jiaquan Li, Qiaoting Deng, Xunwei Deng. Diagnostic values of MMP-7, MMP-9, MMP-11, TIMP-1, TIMP-2, CEA, and CA19-9 in patients with colorectal cancer.
The Journal of international medical research.
2021 May; 49(5):3000605211012570. doi:
10.1177/03000605211012570. [PMID: 33942633] - Shu-Ling Pen, Yan-Shen Shan, Chin-Fu Hsiao, Tsang-Wu Liu, Jen-Shi Chen, Ching-Liang Ho, Wen-Chi Chou, Ruey-Kuen Hsieh, Li-Tzong Chen, Hui-Ju Ch'ang. High expression of krüppel-like factor 10 or Smad4 predicts clinical benefit of adjuvant chemoradiotherapy in curatively resected pancreatic adenocarcinoma: From a randomized phase III trial.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
2021 05; 158(?):146-154. doi:
10.1016/j.radonc.2021.02.037. [PMID: 33667587] - Shounak Majumder, William R Taylor, Patrick H Foote, Calise K Berger, Chung Wah Wu, Douglas W Mahoney, William R Bamlet, Kelli N Burger, Neil Postier, Jaime de la Fuente, Karen A Doering, Graham P Lidgard, Hatim T Allawi, Gloria M Petersen, Suresh T Chari, David A Ahlquist, John B Kisiel. High Detection Rates of Pancreatic Cancer Across Stages by Plasma Assay of Novel Methylated DNA Markers and CA19-9.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2021 05; 27(9):2523-2532. doi:
10.1158/1078-0432.ccr-20-0235. [PMID: 33593879] - Jingru Yu, Alexander Ploner, Maximilian Kordes, Matthias Löhr, Magnus Nilsson, Maria Evangelina Lopez de Maturana, Lidia Estudillo, Harald Renz, Alfredo Carrato, Xavier Molero, Francisco X Real, Núria Malats, Weimin Ye. Plasma protein biomarkers for early detection of pancreatic ductal adenocarcinoma.
International journal of cancer.
2021 04; 148(8):2048-2058. doi:
10.1002/ijc.33464. [PMID: 33411965] - Hui Rao, Heming Wu, Qingyan Huang, Zhikang Yu, Zhixiong Zhong. Clinical Value of Serum CEA, CA24-2 and CA19-9 in Patients with Colorectal Cancer.
Clinical laboratory.
2021 Apr; 67(4):. doi:
10.7754/clin.lab.2020.200828. [PMID: 33865243] - Kiarad Fendereski, Amirreza Nabighadim, Maryam Seyedtabib, Seyedeh Sima Daryabari, Mohammad Taghi Haghi-Ashtiani, Abdol-Mohammad Kajbafzadeh. Comparing predictive values of carbohydrate antigen 19-9, neutrophil gelatinase-associated lipocalin, and kidney injury molecule-1 in 161 patients with ureteropelvic junction obstruction.
Pediatric nephrology (Berlin, Germany).
2021 03; 36(3):631-638. doi:
10.1007/s00467-020-04750-w. [PMID: 32936324] - Guolin Yin, Miaomiao Zhang, Bing Zhao, Zaixing Yang. High serum levels of CA 19-9 and CYFRA21-1 caused by renal pelvis urothelial carcinoma: a report of two cases.
The Journal of international medical research.
2021 Mar; 49(3):3000605211002692. doi:
10.1177/03000605211002692. [PMID: 33752511] - N Mattila, Y Hisada, B Przybyla, J Posma, A Jouppila, C Haglund, H Seppänen, N Mackman, R Lassila. Levels of the cancer biomarker CA 19-9 are associated with thrombin generation in plasma from treatment-naïve pancreatic cancer patients.
Thrombosis research.
2021 03; 199(?):21-31. doi:
10.1016/j.thromres.2020.12.018. [PMID: 33385797] - Li-Qi Sun, Li-Si Peng, Jie-Fang Guo, Fei Jiang, Fang Cui, Hao-Jie Huang, Zhen-Dong Jin. Validation of serum tumor biomarkers in predicting advanced cystic mucinous neoplasm of the pancreas.
World journal of gastroenterology.
2021 Feb; 27(6):501-512. doi:
10.3748/wjg.v27.i6.501. [PMID: 33642824] - Peng Xu, XiaoDong Wang, JianJun Qian, ZhengNan Li, Jie Yao, AMan Xu. The prognostic evaluation of CA19-9, D-dimer and TNFAIP3/A20 in patients with pancreatic ductal adenocarcinoma.
Medicine.
2021 Feb; 100(6):e24651. doi:
10.1097/md.0000000000024651. [PMID: 33578593] - Kangjoon Kim, Seung Hyun Yong, Su Hwan Lee, Sang Hoon Lee, Ah Young Leem, Song Yee Kim, Kyungsoo Chung, Eun Young Kim, Ji Ye Jung, Moo Suk Park, Young Sam Kim, Hye-Jeong Lee, Young Ae Kang. Correlation between serum carbohydrate antigen 19-9 levels and computed tomography severity score in patients with nontuberculous mycobacterial pulmonary disease.
Scientific reports.
2021 02; 11(1):2777. doi:
10.1038/s41598-021-82363-5. [PMID: 33531571] - Huiquan Gao, Yanzhen Wan, Xiaoyi Fan, Yanyu Dong, Xiaona Ji, Wei Song. The Role of Cholinesterase in Differential Diagnosis between Gastric Cancer and Benign Gastric Diseases.
Clinical laboratory.
2021 Feb; 67(2):. doi:
10.7754/clin.lab.2020.200525. [PMID: 33616318]
