5-Methoxypodophyllotoxin (BioDeep_00000279224)
代谢物信息卡片
化学式: C23H24O9 (444.14202539999997)
中文名称:
谱图信息:
最多检出来源 Viridiplantae(plant) 0.06%
分子结构信息
SMILES: COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=C(C5=C(C=C24)OCO5)OC)O
InChI: InChI=1S/C23H24O9/c1-26-13-5-10(6-14(27-2)20(13)28-3)16-11-7-15-21(32-9-31-15)22(29-4)18(11)19(24)12-8-30-23(25)17(12)16/h5-7,12,16-17,19,24H,8-9H2,1-4H3/t12-,16+,17-,19+/m0/s1
描述信息
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.156
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.096
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.064
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.075
同义名列表
1 个代谢物同义名
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:188507
- PubChem: 3035544
- PubChem: 10094984
- ChEMBL: CHEMBL292945
- MetaCyc: CPD-8962
- CAS: 128443-52-7
- MoNA: BML82443
- MoNA: BML82442
- MoNA: BML82441
- MoNA: BML82440
- PMhub: MS000016172
分类词条
相关代谢途径
Reactome(0)
代谢反应
4 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(2)
- podophyllotoxin glucosides metabolism:
H2O + podophyllotoxin 7-glucoside ⟶ D-glucopyranose + podophyllotoxin
- 6-methoxypodophyllotoxin biosynthesis:
(-)-yatein + 2-oxoglutarate + O2 ⟶ (-)-deoxypodophyllotoxin + CO2 + H2O + succinate
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(2)
- podophyllotoxin glucosides metabolism:
UDP-α-D-glucose + podophyllotoxin ⟶ H+ + UDP + podophyllotoxin 7-glucoside
- 6-methoxypodophyllotoxin biosynthesis:
(-)-yatein + 2-oxoglutarate + O2 ⟶ (-)-deoxypodophyllotoxin + CO2 + H2O + succinate
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 191219 - Linum album: 10.1007/978-3-642-57970-7_15
- 4006 - Linum usitatissimum: 10.1007/978-3-642-57970-7_15
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Ashish Baldi, Ashok K Srivastava, Virendra S Bisaria. Effect of aeration on production of anticancer lignans by cell suspension cultures of Linum album.
Applied biochemistry and biotechnology.
2008 Dec; 151(2-3):547-55. doi:
10.1007/s12010-008-8230-3
. [PMID: 18516505] - Ashish Baldi, Abhishek Jain, Nishant Gupta, A K Srivastava, V S Bisaria. Co-culture of arbuscular mycorrhiza-like fungi (Piriformospora indica and Sebacina vermifera) with plant cells of Linum album for enhanced production of podophyllotoxins: a first report.
Biotechnology letters.
2008 Sep; 30(9):1671-7. doi:
10.1007/s10529-008-9736-z
. [PMID: 18427926] - Sunita Farkya, Virendra Swarup Bisaria. Exogenous hormones affecting morphology and biosynthetic potential of hairy root line (LYR2i) of Linum album.
Journal of bioscience and bioengineering.
2008 Feb; 105(2):140-6. doi:
10.1263/jbb.105.140
. [PMID: 18343341] - Abdolali Mohagheghzadeh, Azra Gholami, Shiva Hemmati, Shadab Dehshahri. Bag culture: a method for root-root co-culture.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2008 Jan; 63(1-2):157-60. doi:
10.1515/znc-2008-1-229
. [PMID: 18386507] - Ying-Jun Zhang, Marc Litaudon, Hadjira Bousserouel, Marie-Therese Martin, Odile Thoison, Stéphane Léonce, Vincent Dumontet, Thierry Sévenet, Francoise Guéritte. Sesquiterpenoids and cytotoxic lignans from the bark of Libocedrus chevalieri.
Journal of natural products.
2007 Aug; 70(8):1368-70. doi:
10.1021/np070124q
. [PMID: 17676899] - Abdolali Mohagheghzadeh, Azra Gholami, Shiva Hemmati, Mohammad Reza Shams Ardakani, Thomas J Schmidt, A Wilhelm Alfermann. Root cultures of linum species section Syllinum as rich sources of 6-methoxypodophyllotoxin.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2007 Jan; 62(1-2):43-9. doi:
10.1515/znc-2007-1-208
. [PMID: 17425104] - Anna Berim, Otmar Spring, Jürgen Conrad, Matthias Maitrejean, Wilhelm Boland, Maike Petersen. Enhancement of lignan biosynthesis in suspension cultures of Linum nodiflorum by coronalon, indanoyl-isoleucine and methyl jasmonate.
Planta.
2005 Nov; 222(5):769-76. doi:
10.1007/s00425-005-0019-9
. [PMID: 16136333] - Betina van Fürden, Anne Humburg, Elisabeth Fuss. Influence of methyl jasmonate on podophyllotoxin and 6-methoxypodophyllotoxin accumulation in Linum album cell suspension cultures.
Plant cell reports.
2005 Jul; 24(5):312-7. doi:
10.1007/s00299-005-0954-8
. [PMID: 15818489] - Abdolali Mohagheghzadeh, Azra Gholami, Mohammad Soltani, Shiva Hemmati, A Wilhelm Alfermann. Linum mucronatum: organ to organ lignan variations.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2005 May; 60(5-6):508-10. doi:
10.1515/znc-2005-5-622
. [PMID: 16042353] - Nikolay Vasilev, Iliana Ionkova. Lignan accumulation in cell cultures of Linum strictum ssp. strictum L.
Acta pharmaceutica (Zagreb, Croatia).
2004 Dec; 54(4):347-51. doi:
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. [PMID: 15634618] - Murat Kartal, Belma Konuklugil, Gunawan Indrayanto, A W Alfermann. Comparison of different extraction methods for the determination of podophyllotoxin and 6-methoxypodophyllotoxin in Linum species.
Journal of pharmaceutical and biomedical analysis.
2004 May; 35(3):441-7. doi:
10.1016/j.jpba.2004.01.016
. [PMID: 15137970] - . .
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