Coralyne (BioDeep_00000278291)
natural product
代谢物信息卡片
化学式: C22H22NO4+ (364.15487520000005)
中文名称:
谱图信息:
最多检出来源 Viridiplantae(plant) 75%
分子结构信息
SMILES: CC1=C2C=C(C(=CC2=CC3=[N+]1C=CC4=CC(=C(C=C43)OC)OC)OC)OC
InChI: InChI=1S/C22H22NO4/c1-13-16-11-21(26-4)20(25-3)10-15(16)8-18-17-12-22(27-5)19(24-2)9-14(17)6-7-23(13)18/h6-12H,1-5H3/q+1
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:104157
- PubChem: 23307
- ChEMBL: CHEMBL1184668
- CAS: 1031265-39-0
- CAS: 38989-37-6
- MoNA: Bruker_HCD_library001725
- PMhub: MS000013991
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Daniela Marasco, Caterina Vicidomini, Pawel Krupa, Federica Cioffi, Pham Dinh Quoc Huy, Mai Suan Li, Daniele Florio, Kerensa Broersen, Maria Francesca De Pandis, Giovanni N Roviello. Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine-based compounds on β-amyloid aggregation.
Chemico-biological interactions.
2021 Jan; 334(?):109300. doi:
10.1016/j.cbi.2020.109300
. [PMID: 33098838] - Szu-Ying Hung, Wei-Lung Tseng. A polyadenosine-coralyne complex as a novel fluorescent probe for the sensitive and selective detection of heparin in plasma.
Biosensors & bioelectronics.
2014 Jul; 57(?):186-91. doi:
10.1016/j.bios.2014.02.010
. [PMID: 24583690] - Chia-Yin Kuo, Wei-Lung Tseng. Adenosine-based molecular beacons as light-up probes for sensing heparin in plasma.
Chemical communications (Cambridge, England).
2013 May; 49(41):4607-9. doi:
10.1039/c3cc40976g
. [PMID: 23563586] - Asma Yasmeen Khan, Maidul Hossain, Gopinatha Suresh Kumar. Investigations on the interaction of the phototoxic alkaloid coralyne with serum albumins.
Chemosphere.
2012 May; 87(7):775-81. doi:
10.1016/j.chemosphere.2011.12.079
. [PMID: 22305193] - Prabal Giri, Gopinatha Suresh Kumar. Molecular recognition of poly(A) targeting by protoberberine alkaloids: in vitro biophysical studies and biological perspectives.
Molecular bioSystems.
2010 Jan; 6(1):81-8. doi:
10.1039/b910706a
. [PMID: 20024069] - Md Maidul Islam, Sebanti Roy Chowdhury, Gopinatha Suresh Kumar. Spectroscopic and calorimetric studies on the binding of alkaloids berberine, palmatine and coralyne to double stranded RNA polynucleotides.
The journal of physical chemistry. B.
2009 Jan; 113(4):1210-24. doi:
10.1021/jp806597w
. [PMID: 19132839] - Kakali Bhadra, Motilal Maiti, Gopinatha Suresh Kumar. DNA-binding cytotoxic alkaloids: comparative study of the energetics of binding of berberine, palmatine, and coralyne.
DNA and cell biology.
2008 Dec; 27(12):675-85. doi:
10.1089/dna.2008.0779
. [PMID: 18788977] - J M Finkel, D L Hill. Fluorometric assay for measuring biological half-life of coralyne sulfoacetate in dogs and monkeys.
Journal of pharmaceutical sciences.
1978 Sep; 67(9):1331-2. doi:
10.1002/jps.2600670942
. [PMID: 99510] - J Plowman, R L Cysyk, R H Adamson. The disposition of coralyne sulphoacetate in rodents.
Xenobiotica; the fate of foreign compounds in biological systems.
1976 May; 6(5):281-94. doi:
10.3109/00498257609151640
. [PMID: 936648]