oregonin (BioDeep_00000277669)

   

natural product


代谢物信息卡片


oregonin

化学式: C24H30O10 (478.183888)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 6.06%

分子结构信息

SMILES: C1C(C(C(C(O1)OC(CCC2=CC(=C(C=C2)O)O)CC(=O)CCC3=CC(=C(C=C3)O)O)O)O)O
InChI: InChI=1S/C24H30O10/c25-15(5-1-13-3-7-17(26)19(28)9-13)11-16(6-2-14-4-8-18(27)20(29)10-14)34-24-23(32)22(31)21(30)12-33-24/h3-4,7-10,16,21-24,26-32H,1-2,5-6,11-12H2/t16-,21+,22-,23+,24-/m0/s1

描述信息

同义名列表

1 个代谢物同义名

oregonin



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Hee Jung Kim, Yoon Seo Jang, Ji Won Ha, Moon-Jin Ra, Sang-Mi Jung, Jeong-Nam Yu, Kyunga Kim, Ki Hyun Kim, Sung Hee Um. Bioactive Phytochemicals from Salix pseudolasiogyne Twigs: Anti-Adipogenic Effect of 2'-O-Acetylsalicortin in 3T3-L1 Cells. International journal of molecular sciences. 2022 Oct; 23(19):. doi: 10.3390/ijms231912006. [PMID: 36233307]
  • Kennedy Boateng, Barbara J Hawkins, Alvin Yanchuk, Christin Fellenberg, C Peter Constabel. Factors Affecting Foliar Oregonin and Condensed Tannin in Red Alder (Alnus rubra Bong.): Phytochemicals Implicated In Defense Against Western Tent Caterpillar (Malacosoma californicum Packard). Journal of chemical ecology. 2021 Jul; 47(7):680-688. doi: 10.1007/s10886-021-01283-w. [PMID: 34101117]
  • Carmen S Lea, Chakravarthi Simhadri, Stephen G Bradbury, Jeremy E Wulff, C Peter Constabel. Efficient purification of the diarylheptanoid oregonin from red alder (Alnus rubra) leaves and bark combining aqueous extraction, spray drying and flash-chromatography. Phytochemical analysis : PCA. 2021 Jul; 32(4):554-561. doi: 10.1002/pca.3005. [PMID: 33094496]
  • Carmen S Lea, Stephen G Bradbury, C Peter Constabel. Anti-Herbivore Activity of Oregonin, a Diarylheptanoid Found in Leaves and Bark of Red Alder (Alnus rubra). Journal of chemical ecology. 2021 Feb; 47(2):215-226. doi: 10.1007/s10886-021-01244-3. [PMID: 33475940]
  • Corinne Vanucci-Bacqué, Florence Bedos-Belval. Anti-inflammatory activity of naturally occuring diarylheptanoids - A review. Bioorganic & medicinal chemistry. 2021 02; 31(?):115971. doi: 10.1016/j.bmc.2020.115971. [PMID: 33422907]
  • Desislava Abadjieva, Stanimir Yotov, Vanya Mladenova, Liga Lauberte, Ismet Kalvanov, Jelena Krasilnikova, Galina Telesheva, Elena Kistanova. Positive effect of natural antioxidant oregonin from Alnus incana bark on ram semen quality stored at 5 °C for 48 h. Research in veterinary science. 2020 Aug; 131(?):153-158. doi: 10.1016/j.rvsc.2020.04.021. [PMID: 32387554]
  • Jelena Krasilnikova, Liga Lauberte, Elena Stoyanova, Desislava Abadjieva, Mihail Chervenkov, Mattia Mori, Elisa De Paolis, Vanya Mladenova, Galina Telysheva, Bruno Botta, Elena Kistanova. Oregonin from Alnus incana bark affects DNA methyltransferases expression and mitochondrial DNA copies in mouse embryonic fibroblasts. Journal of enzyme inhibition and medicinal chemistry. 2018 Dec; 33(1):1055-1063. doi: 10.1080/14756366.2018.1476504. [PMID: 29877148]
  • Amin Abedini, Sébastien Chollet, Apostolis Angelis, Nicolas Borie, Jean-Marc Nuzillard, Alexios-Leandros Skaltsounis, Romain Reynaud, Sophie C Gangloff, Jean-Hugues Renault, Jane Hubert. Bioactivity-guided identification of antimicrobial metabolites in Alnus glutinosa bark and optimization of oregonin purification by Centrifugal Partition Chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2016 Sep; 1029-1030(?):121-127. doi: 10.1016/j.jchromb.2016.07.021. [PMID: 27428455]
  • Eszter Riethmüller, Gergő Tóth, Ágnes Alberti, Krisztina Végh, Ilaria Burlini, Árpád Könczöl, György Tibor Balogh, Ágnes Kéry. First characterisation of flavonoid- and diarylheptanoid-type antioxidant phenolics in Corylus maxima by HPLC-DAD-ESI-MS. Journal of pharmaceutical and biomedical analysis. 2015 Mar; 107(?):159-67. doi: 10.1016/j.jpba.2014.12.016. [PMID: 25594894]
  • Annika Lundqvist, Lisa U Magnusson, Christina Ullström, Jelena Krasilnikova, Galina Telysheva, Tatjana Dizhbite, Lillemor Mattsson Hultén. Oregonin reduces lipid accumulation and proinflammatory responses in primary human macrophages. Biochemical and biophysical research communications. 2015 Mar; 458(3):693-699. doi: 10.1016/j.bbrc.2015.01.161. [PMID: 25686497]
  • Nguyen Huu Tung, Kai Sun, Jing-Yu Fan, Yukihiro Shoyama, Jing-Yan Han. Oregonin from the Bark of Alnus japonica restrained ischemia-reperfusion-induced mesentery oxidative stress by inhibiting NADPH oxidase activation. Microcirculation (New York, N.Y. : 1994). 2014 Nov; 21(8):688-95. doi: 10.1111/micc.12147. [PMID: 24852886]
  • Onseok Lee, Jaeyoung Kim, Young Wook Choi, Minwon Lee, Gyuman Park, Chilhwan Oh. Efficacy of oregonin investigated by non-invasive evaluation in a B16 mouse melanoma model. Experimental dermatology. 2013 Dec; 22(12):842-4. doi: 10.1111/exd.12277. [PMID: 24171727]
  • Mina Lee, Ji Yeon Song, Young-Won Chin, Sang Hyun Sung. Anti-adipogenic diarylheptanoids from Alnus hirsuta f. sibirica on 3T3-L1 cells. Bioorganic & medicinal chemistry letters. 2013 Apr; 23(7):2069-73. doi: 10.1016/j.bmcl.2013.01.127. [PMID: 23465614]
  • J G Choi, M W Lee, S E Choi, M H Kim, O H Kang, Y S Lee, H S Chae, B Obiang-Obounou, Y C Oh, M R Kim, D W Shin, J H Lee, D Y Kwon. Antibacterial activity of bark of Alnus pendula against methicillin-resistant Staphylococcus aureus. European review for medical and pharmacological sciences. 2012 Jul; 16(7):853-9. doi: ". [PMID: 22953631]
  • Mina Lee, Mi Kyeong Lee, Young Choong Kim, Sang Hyun Sung. Antifibrotic constituents of Alnus firma on hepatic stellate cells. Bioorganic & medicinal chemistry letters. 2011 May; 21(10):2906-10. doi: 10.1016/j.bmcl.2011.03.074. [PMID: 21504848]
  • Louis C Martineau, Asim Muhammad, Ammar Saleem, Jessica Hervé, Cory S Harris, John T Arnason, Pierre S Haddad. Anti-adipogenic activities of Alnus incana and Populus balsamifera bark extracts, part II: bioassay-guided identification of actives salicortin and oregonin. Planta medica. 2010 Oct; 76(14):1519-24. doi: 10.1055/s-0029-1240991. [PMID: 20301058]
  • Sun Eun Choi, Mi Sook Jeong, Myung Joo Kang, Do Ik Lee, Seong Soo Joo, Chung Soo Lee, Hyoweon Bang, Mi-Kyung Lee, Soon-Chul Myung, Young Wook Choi, Kap-Sok Lee, Seong Jun Seo, Min Won Lee. Effect of topical application and intraperitoneal injection of oregonin on atopic dermatitis in NC/Nga mice. Experimental dermatology. 2010 Aug; 19(8):e37-43. doi: 10.1111/j.1600-0625.2009.00961.x. [PMID: 19849716]
  • Nguyen Huu Tung, Hyuk-Joon Kwon, Jae-Hong Kim, Jeong Chan Ra, Yan Ding, Jeong Ah Kim, Young Ho Kim. Anti-influenza diarylheptanoids from the bark of Alnus japonica. Bioorganic & medicinal chemistry letters. 2010 Feb; 20(3):1000-3. doi: 10.1016/j.bmcl.2009.12.057. [PMID: 20045319]
  • Myung Joo Kang, Jae Yoon Eum, Mi Sook Jeong, Sun Eun Choi, Sang Han Park, Hye In Cho, Chin Sung Cho, Seong Jun Seo, Min Won Lee, Young Wook Choi. Facilitated skin permeation of oregonin by elastic liposomal formulations and suppression of atopic dermatitis in NC/Nga mice. Biological & pharmaceutical bulletin. 2010; 33(1):100-6. doi: 10.1248/bpb.33.100. [PMID: 20045944]
  • Jong-Min Han, Woo Song Lee, Ju-Ryoung Kim, Joonsok Son, Ki-Hoan Nam, Seung-Chul Choi, Jong-Seok Lim, Tae-Sook Jeong. Effects of diarylheptanoids on the tumor necrosis factor-alpha-induced expression of adhesion molecules in human umbilical vein endothelial cells. Journal of agricultural and food chemistry. 2007 Nov; 55(23):9457-64. doi: 10.1021/jf072157h. [PMID: 17929893]