Vinylacetylglycine (BioDeep_00000027664)

   

human metabolite Endogenous


代谢物信息卡片


2-(But-3-enamido)acetic acid

化学式: C6H9NO3 (143.0582404)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=CCC(=O)NCC(=O)O
InChI: InChI=1S/C6H9NO3/c1-2-3-5(8)7-4-6(9)10/h2H,1,3-4H2,(H,7,8)(H,9,10)

描述信息

Vinylacetylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction:. acyl-CoA + glycine < -- > CoA + N-acylglycine. Vinylacetylglycine is a human metabolite that had been identified in a GC/MS urine screen. Increased amounts of this metabolite in the urine has been linked to a metabolomic disorder termed Isovaleric acidemia. (Gas-Chromatographic Method of Analysis for Urinary Organic Acids. I. Retention indices of 155 metaboically Important Compounds; Kay Tanaka, David G. Hine, Agnes West-Dull, and Theodore B. Lynn.).
Vinylacetylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction:

同义名列表

4 个代谢物同义名

2-(But-3-enamido)acetic acid; but-3-enamidoacetic acid; 2-(But-3-enamido)acetate; Vinylacetylglycine



数据库引用编号

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相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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2 个相关的物种来源信息

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