Monoiodothyronine (BioDeep_00000027651)

   

human metabolite Endogenous


代谢物信息卡片


(2R)-2-amino-3-[4-(4-hydroxyphenoxy)-3-iodophenyl]propanoic acid

化学式: C15H14INO4 (398.99675540000004)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1O)OC2=C(C=C(C=C2)CC(C(=O)O)N)I
InChI: InChI=1S/C15H14INO4/c16-12-7-9(8-13(17)15(19)20)1-6-14(12)21-11-4-2-10(18)3-5-11/h1-7,13,18H,8,17H2,(H,19,20)/t13-/m1/s1

描述信息

Monoiodothyronine is an iodothyronine metabolite. It has unknown physiological functions. [HMDB]
Monoiodothyronine is an iodothyronine metabolite. It has unknown physiological functions.
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones

同义名列表

11 个代谢物同义名

(2R)-2-amino-3-[4-(4-hydroxyphenoxy)-3-iodophenyl]propanoic acid; (2R)-2-Amino-3-[4-(4-hydroxyphenoxy)-3-iodophenyl]propanoate; 3-Monoiodothyronine, 125I-labeled, (L-tyr)-isomer; 3-Monoiodothyronine, (DL-tyr)-isomer; 3-Monoiodothyronine, (L-tyr)-isomer; O-(4-Hydroxyphenyl)-3-iodotyrosine; 3-Monoiodothyronine; Monoiodothyronine; 3-Iodothyronine; Iodo-thyronine; 3-T1



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ariel A Petruk, Marcelo C Sosa Morales, Rosa M S Álvarez. Iodothyronine-phospholipid interactions in the lipid gel phase probed by Raman spectral markers. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2013 Aug; 112(?):403-9. doi: 10.1016/j.saa.2013.04.094. [PMID: 23694898]
  • Sarah A Hackenmueller, Thomas S Scanlan. Identification and quantification of 3-iodothyronamine metabolites in mouse serum using liquid chromatography-tandem mass spectrometry. Journal of chromatography. A. 2012 Sep; 1256(?):89-97. doi: 10.1016/j.chroma.2012.07.052. [PMID: 22885046]
  • Marija Trajkovic, Theo J Visser, Jens Mittag, Sigrun Horn, Jan Lukas, Veerle M Darras, Genadij Raivich, Karl Bauer, Heike Heuer. Abnormal thyroid hormone metabolism in mice lacking the monocarboxylate transporter 8. The Journal of clinical investigation. 2007 Mar; 117(3):627-35. doi: 10.1172/jci28253. [PMID: 17318265]
  • Monique H A Kester, Ellen Kaptein, Caren H Van Dijk, Thirza J Roest, Dick Tibboel, Michael W H Coughtrie, Theo J Visser. Characterization of iodothyronine sulfatase activities in human and rat liver and placenta. Endocrinology. 2002 Mar; 143(3):814-9. doi: 10.1210/endo.143.3.8686. [PMID: 11861502]
  • F Santini, R E Hurd, B Lee, I J Chopra. Sex-related differences in iodothyronine metabolism in the rat: evidence for differential regulation among various tissues. Metabolism: clinical and experimental. 1994 Jun; 43(6):793-7. doi: 10.1016/0026-0495(94)90133-3. [PMID: 8201972]
  • G Perret, Y L Yin, P Nicolas, R Vassy, B Uzzan, M Louchahi. In vivo effects of macrolides on thyroid hormone serum levels and on hepatic type 1 5'-deiodinase in rat. A comparative study with amiodarone, phenobarbital and propranolol. Fundamental & clinical pharmacology. 1991; 5(7):583-93. doi: 10.1111/j.1472-8206.1991.tb00747.x. [PMID: 1778536]
  • K Ashizawa, S Nagataki. [Clinical significance of serum monoiodothyronine analysis in endocrine tests of the thyroid-parathyroid system]. Nihon rinsho. Japanese journal of clinical medicine. 1989 Dec; 48 Suppl(?):1126-9. doi: NULL. [PMID: 2621832]
  • P R Koostra, H H van den Broek, E A Hogendoorn, C E Goewie, J J de Vijlder. Automated high-performance liquid chromatographic method for the determination of iodotyrosines and iodothyronines. Journal of chromatography. 1988 Dec; 458(?):175-83. doi: 10.1016/s0021-9673(00)90562-4. [PMID: 3235633]
  • P Nokin, J J Mercadier, D Nahum, P Bouveret, C Wisnewsky, L Jungbluth, J P Gagnol, K Schwartz. Effect of amiodarone on myosin isoenzymic distribution in rat ventricular myocardium. European journal of pharmacology. 1987 Jun; 138(2):277-80. doi: 10.1016/0014-2999(87)90444-4. [PMID: 3622612]
  • S K Lam, S Harvey, C G Scanes. Somatostatin inhibits thyroid function in fowl. General and comparative endocrinology. 1986 Jul; 63(1):134-8. doi: 10.1016/0016-6480(86)90191-7. [PMID: 2876926]
  • J T Hidal, M M Kaplan. Characteristics of thyroxine 5'-deiodination in cultured human placental cells. Regulation by iodothyronines. The Journal of clinical investigation. 1985 Sep; 76(3):947-55. doi: 10.1172/jci112094. [PMID: 2413075]
  • N Okabe, E Takimoto. The binding of a thyroid hormone metabolite, 3-monoiodo-L-thyronine, to bovine serum albumin as measured by circular dichroism. Journal of biochemistry. 1985 May; 97(5):1317-22. doi: 10.1093/oxfordjournals.jbchem.a135183. [PMID: 4030725]
  • P G Byfield, S Copping, R L Himsworth. Subfractionation of human immunoglobulin G with dye-Sepharose adsorbents. Molecular immunology. 1984 Jul; 21(7):647-52. doi: 10.1016/0161-5890(84)90050-6. [PMID: 6749137]
  • I J Chopra, T S Huang, R E Hurd, D H Solomon. Thyromimetic effects of 3,5-dimethyl,3'-isopropyl thyronine (DIMIT) and 3,5-diethyl,3'-isopropyl thyronine (DIET) in various tissues of the rat. Metabolism: clinical and experimental. 1984 Jul; 33(7):622-8. doi: 10.1016/0026-0495(84)90060-x. [PMID: 6738362]
  • U D McCann, E A Shaw, M M Kaplan. Iodothyronine deiodination reaction types in several rat tissues: effects of age, thyroid status, and glucocorticoid treatment. Endocrinology. 1984 May; 114(5):1513-21. doi: 10.1210/endo-114-5-1513. [PMID: 6714153]
  • J M Corcoran, C J Eastman. Radioimmunoassay of 3-L-monoiodothyronine: application in normal human physiology and thyroid disease. The Journal of clinical endocrinology and metabolism. 1983 Jul; 57(1):66-70. doi: 10.1210/jcem-57-1-66. [PMID: 6853682]
  • M Mirakhmedov, Ia Kh Turakulov. [Role of iodothyronine metabolism in the regulation of body thyroid status]. Vestnik Akademii meditsinskikh nauk SSSR. 1983; ?(2):64-9. doi: NULL. [PMID: 6837140]
  • R C Smallridge, L Wartofsky, K D Burman. The effect of experimental hyperthyroidism and hypothyroidism on 5'-monodeiodination of 3,3',5'-triiodothyronine and 3',5'-diiodothyronine by rat liver and kidney. Endocrinology. 1982 Dec; 111(6):2066-9. doi: 10.1210/endo-111-6-2066. [PMID: 7140645]
  • S Jaedig, J Faber. The effect of starvation and refeeding with oral versus intravenous glucose on serum 3,5-,3,3'-and 3'-5'-diiodothyronine and 3'-monoiodothyronine. Acta endocrinologica. 1982 Jul; 100(3):388-92. doi: 10.1530/acta.0.1000388. [PMID: 7113605]
  • I B Lumholtz, J Faber, C Kirkegaard, K Siersbaek-Nielsen, T Friis. The extrathyroidal effect of D,L-propranolol on 3,3',5'-triiodothyronine, 3',5'-diiodothyronine, 3,3'-diiodothyronine, and 3'-monoiodothyronine kinetics. The Journal of clinical endocrinology and metabolism. 1982 Jun; 54(6):1097-100. doi: 10.1210/jcem-54-6-1097. [PMID: 7076792]
  • C Kirkegaard, J Faber, D Cohn, K Kølendorf, H F Thomsen, I B Lumholtz, K Siersbaek-Nielsen, T Friis. Serum 3'-monoiodothyronine levels in normal subjects and in patients with thyroid and non-thyroid disease. Acta endocrinologica. 1981 Aug; 97(4):454-60. doi: 10.1530/acta.0.0970454. [PMID: 7270005]