Ioxitalamic acid (BioDeep_00000276073)
代谢物信息卡片
化学式: C12H11I3N2O5 (643.7802246)
中文名称: 碘羟拉酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)C(=O)NCCO)I
InChI: InChI=1S/C12H11I3N2O5/c1-4(19)17-10-8(14)5(11(20)16-2-3-18)7(13)6(9(10)15)12(21)22/h18H,2-3H2,1H3,(H,16,20)(H,17,19)(H,21,22)
描述信息
V - Various > V08 - Contrast media > V08A - X-ray contrast media, iodinated > V08AA - Watersoluble, nephrotropic, high osmolar x-ray contrast media
D006133 - Growth Substances > D010937 - Plant Growth Regulators > D014283 - Triiodobenzoic Acids
CONFIDENCE standard compound; EAWAG_UCHEM_ID 342
同义名列表
1 个代谢物同义名
数据库引用编号
21 个数据库交叉引用编号
- ChEBI: CHEBI:83517
- KEGGdrug: D07418
- PubChem: 34536
- DrugBank: DB13444
- ChEMBL: CHEMBL2107239
- CAS: 28179-44-4
- MoNA: EA034214
- MoNA: EA034213
- MoNA: EA034212
- MoNA: EA034211
- MoNA: EA034210
- MoNA: EA034209
- MoNA: EA034208
- MoNA: EA034207
- MoNA: EA034206
- MoNA: EA034205
- MoNA: EA034204
- MoNA: EA034203
- MoNA: EA034202
- MoNA: EA034201
- PMhub: MS000009248
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Laure Cohen, Marie Pouletty, Alice Frerot, Anca Tanase, Liza Ali, Véronique Baudouin. Voiding cystography: an unusual route of induced hypothyroidism by iodine overdose in two newborns with chronic kidney disease.
Pediatric nephrology (Berlin, Germany).
2019 07; 34(7):1295-1297. doi:
10.1007/s00467-019-04247-1
. [PMID: 30937552] - Yen Ta Huang, Yi Ya Chen, Yu Hsien Lai, Chuan Chu Cheng, Tzu Chun Lin, Ying Shih Su, Chin Hung Liu, Pei Chun Lai. Resveratrol alleviates the cytotoxicity induced by the radiocontrast agent, ioxitalamate, by reducing the production of reactive oxygen species in HK-2 human renal proximal tubule epithelial cells in vitro.
International journal of molecular medicine.
2016 Jan; 37(1):83-91. doi:
10.3892/ijmm.2015.2404
. [PMID: 26573558] - Antonio Jose Inda-Filho, Adriano Caixeta, Marcia Manggini, Nestor Schor. Do intravenous N-acetylcysteine and sodium bicarbonate prevent high osmolal contrast-induced acute kidney injury? A randomized controlled trial.
PloS one.
2014; 9(9):e107602. doi:
10.1371/journal.pone.0107602
. [PMID: 25254489] - Hsiang-Chun Lee, Sheng-Hsiung Sheu, I-Hsin Liu, Chien-Chih Lee, Chong-Chao Hsieh, Hsueh-Wei Yen, Wen-Ter Lai, Jan-Gowth Chang. Impact of short-duration administration of N-acetylcysteine, probucol and ascorbic acid on contrast-induced cytotoxicity.
Journal of nephrology.
2012 Jan; 25(1):56-62. doi:
10.5301/jn.2011.7741
. [PMID: 21534235] - Shih-Ping Hsu, Tun-Jun Tsai, Chiang-Ting Chien. Ioxitalamate induces renal tubular apoptosis via activation of renal efferent nerve-mediated adrenergic signaling, renin activity, and reactive oxygen species production in rats.
Toxicological sciences : an official journal of the Society of Toxicology.
2010 Mar; 114(1):149-58. doi:
10.1093/toxsci/kfp290
. [PMID: 19945959] - Jan Sochman, Jan H Peregrin, Marcela Bürgelová, Libor Kopkan, Herbert J Kramer, Ludek Cervenka. N-acetylcysteine attenuates iodine contrast agent-induced nephropathy in 5/6-nephrectomized rats.
Kidney & blood pressure research.
2010; 33(2):149-56. doi:
10.1159/000315435
. [PMID: 20502036] - Le Tan Son, Le Cong Thang, Le Thanh Hung, Nguyen Thi Dan Tram. Single ectopic ureter: diagnostic value of contrast vaginography.
Urology.
2009 Aug; 74(2):314-7. doi:
10.1016/j.urology.2009.02.067
. [PMID: 19476979] - Shai Efrati, Sylvia Berman, Ilia Ilgiyeav, Yariv Siman-Tov, Zhan Averbukh, Joshua Weissgarten. Differential effects of N-acetylcysteine, theophylline or bicarbonate on contrast-induced rat renal vasoconstriction.
American journal of nephrology.
2009; 29(3):181-91. doi:
10.1159/000154471
. [PMID: 18781062] - Ayso H de Vries, Henk W Venema, Jasper Florie, Chung Y Nio, Jaap Stoker. Influence of tagged fecal material on detectability of colorectal polyps at CT: phantom study.
AJR. American journal of roentgenology.
2008 Oct; 191(4):1101. doi:
10.2214/ajr.07.3740
. [PMID: 18806150] - P Bruners, H Müller, R W Günther, T Schmitz-Rode, A H Mahnken. Fluid-modulated bipolar radiofrequency ablation: an ex-vivo evaluation study.
Acta radiologica (Stockholm, Sweden : 1987).
2008 Apr; 49(3):258-66. doi:
10.1080/02841850701843085
. [PMID: 18365809] - Zh V Vesnina, A M Guliaev, S G Gol'tsov, Iu B Lishmanov. [Renal radionuclide scintigraphy in the evaluation of radiopaque substances on renal function].
Vestnik rentgenologii i radiologii.
2007 Jan; ?(1):36-41. doi:
NULL
. [PMID: 18274140] - Frank Sacher, Brigitte Raue, Heinz-Jürgen Brauch. Analysis of iodinated X-ray contrast agents in water samples by ion chromatography and inductively-coupled plasma mass spectrometry.
Journal of chromatography. A.
2005 Aug; 1085(1):117-23. doi:
10.1016/j.chroma.2005.01.031
. [PMID: 16106857] - Koenraad J Mortelé, Bart Mortelé, Stuart G Silverman. CT features of the accessory spleen.
AJR. American journal of roentgenology.
2004 Dec; 183(6):1653-7. doi:
10.2214/ajr.183.6.01831653
. [PMID: 15547205] - Luciane Ribeiro, Fábio de Assunção e Silva, Rose Saemi Kurihara, Nestor Schor, Elisa Mieko, Suemitsu Higa. Evaluation of the nitric oxide production in rat renal artery smooth muscle cells culture exposed to radiocontrast agents.
Kidney international.
2004 Feb; 65(2):589-96. doi:
10.1111/j.1523-1755.2004.00408.x
. [PMID: 14717929] - O Rouvière, R Ecochard, P Berger, C Pangaud, B Fontaine, D Lyonnet. Low- versus high-osmolality contrast media.
Acta radiologica (Stockholm, Sweden : 1987).
2000 Sep; 41(5):508-13. doi:
10.1034/j.1600-0455.2000.041005508.x
. [PMID: 11016777] - P V Sergeev, N K Sviridov, Iu A Poliaev, N L Shimanovskiĭ. [Diagnostic effectiveness and safety of currently available X-ray contrast media].
Vestnik rentgenologii i radiologii.
1999 Nov; ?(6):45-9. doi:
NULL
. [PMID: 10714233] - C Stellato, G de Crescenzo, V Patella, P Mastronardi, B Mazzarella, G Marone. Human basophil/mast cell releasability. XI. Heterogeneity of the effects of contrast media on mediator release.
The Journal of allergy and clinical immunology.
1996 Mar; 97(3):838-50. doi:
10.1016/s0091-6749(96)80162-x
. [PMID: 8613641] - A Genovese, C Stellato, V Patella, B Lamparter-Schummert, G de Crescenzo, M Adt, G Marone. Contrast media are incomplete secretagogues acting on human basophils and mast cells isolated from heart and lung, but not skin tissue.
International journal of clinical & laboratory research.
1996; 26(3):192-8. doi:
10.1007/bf02592981
. [PMID: 8905451] - A Verbaeys, S Ringoir, D Kesteloot, G Van Maele, N Lameire. Evaluation of renal function before and after intravenous injection of non-cholangiographic water soluble contrast media in rats.
Acta urologica Belgica.
1995 Mar; 63(1):103-8. doi:
NULL
. [PMID: 7725984] - A Nygren. Contrast media and regional renal blood flow. A study of the effects of ionic and non-ionic monomeric and dimeric contrast media in the rat.
Acta radiologica. Supplementum.
1992; 378 ( Pt 3)(?):123-35. doi:
NULL
. [PMID: 1323194] - A Verbaeys, G van Maele, W De Sy, S Ringoir, N Lameire. Absence of functional renal effects of uro-angiographic contrast media on post-ischemic rat kidneys.
Acta radiologica (Stockholm, Sweden : 1987).
1991 Jul; 32(4):325-8. doi:
NULL
. [PMID: 1863506] - M Ennis, W Lorenz, E Nehring, C Schneider. In vitro and in vivo studies of radiographic contrast media-induced histamine release in pigs.
Agents and actions.
1991 May; 33(1-2):26-9. doi:
10.1007/bf01993118
. [PMID: 1716833] - G Deray, M F Bellin, H Boulechfar, B Baumelou, F Koskas, A Baumelou, J Grellet, C Jacobs. Nephrotoxicity of contrast media in high-risk patients with renal insufficiency: comparison of low- and high-osmolar contrast agents.
American journal of nephrology.
1991; 11(4):309-12. doi:
10.1159/000168328
. [PMID: 1799190] - A Verbaeys, N Lameire, D Kesteloot, M Waterloos, G Van Maele, S Ringoir, W De Sy. Evaluation of renal function before and after intravenous injection of non-cholangiographic water soluble contrast media in rats: preliminary results.
Acta urologica Belgica.
1990; 58(3):31-8. doi:
NULL
. [PMID: 2082750] - A Nygren, H R Ulfendahl. Effects of high- and low-osmolar contrast media on renal plasma flow and glomerular filtration rate in euvolaemic and dehydrated rats. A comparison between ioxithalamate, iopamidol, iohexol and ioxaglate.
Acta radiologica (Stockholm, Sweden : 1987).
1989 Jul; 30(4):383-9. doi:
NULL
. [PMID: 2775601] - F Kees, K G Naber, G P Meyer, H Grobecker. Pharmacokinetics of ciprofloxacin in elderly patients.
Arzneimittel-Forschung.
1989 Apr; 39(4):523-7. doi:
NULL
. [PMID: 2751742] - A Verbaeys, N Lameire, W Oosterlinck. Evaluation of renal function before and after intravenous injection of uroangiographic water soluble contrast media in men.
Acta urologica Belgica.
1989; 57(4):795-801. doi:
NULL
. [PMID: 2631582] - A Nygren, H R Ulfendahl, P Hansell, U Erikson. Effects of intravenous contrast media on cortical and medullary blood flow in the rat kidney.
Investigative radiology.
1988 Oct; 23(10):753-61. doi:
10.1097/00004424-198810000-00010
. [PMID: 3056872] - B Bonnemain, C Hartl, A Cardinal, A M Donadieu, E Schouman-Claeys, G Frija. Tolerability of hypertonic and isotonic contrast media injected intravenously. A comparative study in the dog.
Investigative radiology.
1988 Jun; 23(6):478-81. doi:
10.1097/00004424-198806000-00012
. [PMID: 3042686] - J P Morin, I Boutelet, H Toutain, J P Fillastre. Pharmacokinetics and renal accumulation of three iodinated contrast agents. A comparative study of Telebrix, Hexabrix and Omnipaque in the rabbit.
Drugs under experimental and clinical research.
1988; 14(11):679-86. doi:
NULL
. [PMID: 3246213] - J P Morin, I Boutelet, H Toutain, J P Fillastre. [Comparative pharmacokinetics and renal accumulation of the iodized contrast media: ioxitalamic acid, ioxaglic acid and iohexol in the rabbit].
Pathologie-biologie.
1987 Nov; 35(9):1215-20. doi:
NULL
. [PMID: 3320896] - R Krŭsteva, R Dzherasi. [Potentials of echography for diagnosing x-ray-negative calculi].
Vutreshni bolesti.
1987; 26(1):18-21. doi:
NULL
. [PMID: 3296453] - M Attia, P Beroud, C Pharaboz, D Jeanbourquin, C Derosier, G Cosnard. [Delayed, triangular, hyperdense, computed x-ray tomography images of the renal parenchyma following iodide injection. Interpretation of transient renal ischemia?].
Journal de radiologie.
1986 Oct; 67(10):687-91. doi:
NULL
. [PMID: 3795177] - J Buck. [Angiocinedensitometry with ECG-controlled injections in patients with healthy kidneys and kidney tumors].
Der Radiologe.
1986 Jun; 26(6):266-72. doi:
NULL
. [PMID: 3749500] - H J Reimann, R Tauber, B Kramann, J Gmeinwieser, U Schmidt, M Reiser. [Premedication with H1- and H2-receptor antagonists for intravenous urography using contrast media].
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin.
1986 Feb; 144(2):169-73. doi:
10.1055/s-2008-1048766
. [PMID: 2869551] - V Klingmüller. [Enteral resorption of ioxitalamate].
Rontgen-Blatter; Zeitschrift fur Rontgen-Technik und medizinisch-wissenschaftliche Photographie.
1985 Nov; 38(11):350-2. doi:
NULL
. [PMID: 4081555] - M V Helzel, G K Wolf, P Prager. [Experimental and clinical determination of renal size after intravenous and intra-arterial administration of ionic and non-ionic contrast media].
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin.
1985 Mar; 142(3):333-7. doi:
10.1055/s-2008-1052659
. [PMID: 2984739] - F Kees, K G Naber, B Bartoschik-Wich, P Stockmann, G P Meyer, H Grobecker. High-performance liquid chromatography analysis of mezlocillin, piperacillin, their degradation products, and of ioxitalamic acid in plasma and urine of healthy volunteers.
Arzneimittel-Forschung.
1985; 35(7):1099-104. doi:
NULL
. [PMID: 4052146] - I Myara, M S Chamaki, C Lagrange, A Lemonnier. [Interference of several radiological contrast media in the determination of proteinuria].
Annales de biologie clinique.
1985; 43(4):347-8. doi:
NULL
. [PMID: 4091298] - S Benita, P A Poly, F Puisieux, J Delattre. Radiopaque liposomes: effect of formulation conditions on encapsulation efficiency.
Journal of pharmaceutical sciences.
1984 Dec; 73(12):1751-5. doi:
10.1002/jps.2600731223
. [PMID: 6527250] - G Goursot, H Deriaz, P Dufieux, J L Lasry, B Zehrouni, F Ruff. [Serum histamine, osmolality and hemodynamics during aortography].
Annales francaises d'anesthesie et de reanimation.
1984; 3(2):90-3. doi:
10.1016/s0750-7658(84)80003-9
. [PMID: 6201091] - B Lacour, C Lacroix, P Jungers, M Bailly. [Effects of intravenous urography using sodium and meglumine ioxitalamate (Telebrix 38) on blood creatinine and urinary excretion of N-acetyl-beta-D-glucosaminidase].
Annales de biologie clinique.
1984; 42(6):407-11. doi:
NULL
. [PMID: 6532266] - M J Lambert, A G Burger, R L Galeazzi, D Engler. Are selective increases in serum thyroxine (T4) due to iodinated inhibitors of T4 monodeiodination indicative of hyperthyroidism?.
The Journal of clinical endocrinology and metabolism.
1982 Dec; 55(6):1058-65. doi:
10.1210/jcem-55-6-1058
. [PMID: 6813344] - J Belleville, A M Freyria, A Pinet, B Cornillon, J Paul, G Clendinnen, R Eloy. Contrast agents used for excretory urography impair platelet function in human patients.
Thrombosis research.
1982 Nov; 28(4):533-44. doi:
10.1016/0049-3848(82)90169-4
. [PMID: 7164034] - A M Freyria, A Pinet, J Belleville, R Eloy, J Traeger. Effects of five different contrast agents on serum complement and calcium levels after excretory urography.
The Journal of allergy and clinical immunology.
1982 Apr; 69(4):397-403. doi:
10.1016/0091-6749(82)90152-x
. [PMID: 7069076] - D Glomaud, J C Salamagne, F Dauchy, M Tonnelier, L Ngwing Tin, D Malapel. [Ionized plasma calcium variations and injection of radiologic contrast media].
Annales francaises d'anesthesie et de reanimation.
1982; 1(3):297-300. doi:
10.1016/s0750-7658(82)80045-2
. [PMID: 7165144] - D Gardeur, J Lautrou, J C Millard, N Berger, J Metzger. Pharmacokinetics of contrast media: experimental results in dog and man with CT implications.
Journal of computer assisted tomography.
1980 Apr; 4(2):178-85. doi:
10.1097/00004728-198004000-00009
. [PMID: 7365016]