2,4,4-TRICHLOROBIPHENYL (BioDeep_00000275668)
Industrial Pollutants
代谢物信息卡片
2,4-dichloro-1-(4-chlorophenyl)benzene
化学式: C12H7Cl3 (255.96133120000002)
中文名称: 2,4,4-三氯联苯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=CC=C1C2=C(C=C(C=C2)Cl)Cl)Cl
InChI: InChI=1S/C12H7Cl3/c13-9-3-1-8(2-4-9)11-6-5-10(14)7-12(11)15/h1-7H
描述信息
D004785 - Environmental Pollutants > D011078 - Polychlorinated Biphenyls
同义名列表
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Cuiting Wang, Yuan Sun, Honghua Ruan, Jing Yang. Toxic effects of 2,4,4'- trichlorobiphenyl (PCB-28) on growth, photosynthesis characteristics and antioxidant defense system of Lemna minor L.
Plant physiology and biochemistry : PPB.
2021 Sep; 166(?):505-511. doi:
10.1016/j.plaphy.2021.06.031. [PMID: 34166977] - Theresa Vasko, Jenny Hoffmann, Sonja Gostek, Thomas Schettgen, Natalia Quinete, Christian Preisinger, Thomas Kraus, Patrick Ziegler. Telomerase gene expression bioassays indicate metabolic activation of genotoxic lower chlorinated polychlorinated biphenyls.
Scientific reports.
2018 11; 8(1):16903. doi:
10.1038/s41598-018-35043-w. [PMID: 30443001] - Yunlu Jia, Huiling Li, Yueming Qu, Wei Chen, Lirong Song. Phytotoxicity, bioaccumulation and potential risks of plant irrigations using cyanobloom-loading freshwater.
The Science of the total environment.
2018 May; 624(?):704-712. doi:
10.1016/j.scitotenv.2017.12.164. [PMID: 29272839] - Kelsey Benson, Eric Yang, Nina Dutton, Andreas Sjodin, Paula F Rosenbaum, Marian Pavuk. Polychlorinated biphenyls, indicators of thyroid function and thyroid autoantibodies in the Anniston Community Health Survey I (ACHS-I).
Chemosphere.
2018 Mar; 195(?):156-165. doi:
10.1016/j.chemosphere.2017.12.050. [PMID: 29268174] - Natalia Quinete, André Esser, Thomas Kraus, Thomas Schettgen. PCB 28 metabolites elimination kinetics in human plasma on a real case scenario: Study of hydroxylated polychlorinated biphenyl (OH-PCB) metabolites of PCB 28 in a highly exposed German Cohort.
Toxicology letters.
2017 Jul; 276(?):100-107. doi:
10.1016/j.toxlet.2017.05.025. [PMID: 28552772] - Susanne Ziegler, Thomas Schettgen, Fabian Beier, Stefan Wilop, Natalia Quinete, Andre Esser, Behzad Kharabi Masouleh, Monica S V Ferreira, Lucia Vankann, Peter Uciechowski, Lothar Rink, Thomas Kraus, Tim H Brümmendorf, Patrick Ziegler. Accelerated telomere shortening in peripheral blood lymphocytes after occupational polychlorinated biphenyls exposure.
Archives of toxicology.
2017 Jan; 91(1):289-300. doi:
10.1007/s00204-016-1725-8. [PMID: 27146145] - Şafak Ulusoy, Özkan Özden, Olaf Päpke. Distribution of OCPs and PCBs in Mussels (Mytilus galloprovincialis) from the Marmara Sea Coastal Sites.
Bulletin of environmental contamination and toxicology.
2016 Aug; 97(2):191-7. doi:
10.1007/s00128-016-1848-x. [PMID: 27329111] - Emilie Lund Egsmose, Elvira Vaclavik Bräuner, Marie Frederiksen, Thit Aarøe Mørck, Volkert Dirk Siersma, Pernille Winton Hansen, Flemming Nielsen, Philippe Grandjean, Lisbeth E Knudsen. Associations between plasma concentrations of PCB 28 and possible indoor exposure sources in Danish school children and mothers.
Environment international.
2016 Feb; 87(?):13-9. doi:
10.1016/j.envint.2015.11.005. [PMID: 26638015] - Natalia Quinete, Thomas Kraus, Vladimir N Belov, Christina Aretz, André Esser, Thomas Schettgen. Fast determination of hydroxylated polychlorinated biphenyls in human plasma by online solid phase extraction coupled to liquid chromatography-tandem mass spectrometry.
Analytica chimica acta.
2015 Aug; 888(?):94-102. doi:
10.1016/j.aca.2015.06.041. [PMID: 26320963] - Candace A Robledo, Edwina Yeung, Pauline Mendola, Rajeshwari Sundaram, Jose Maisog, Anne M Sweeney, Dana Boyd Barr, Germaine M Buck Louis. Preconception maternal and paternal exposure to persistent organic pollutants and birth size: the LIFE study.
Environmental health perspectives.
2015 Jan; 123(1):88-94. doi:
10.1289/ehp.1308016. [PMID: 25095280] - Hongtao Shang, Yingming Li, Thanh Wang, Pu Wang, Haidong Zhang, Qinghua Zhang, Guibin Jiang. The presence of polychlorinated biphenyls in yellow pigment products in China with emphasis on 3,3'-dichlorobiphenyl (PCB 11).
Chemosphere.
2014 Mar; 98(?):44-50. doi:
10.1016/j.chemosphere.2013.09.075. [PMID: 24231041] - Junchao Yu, Thanh Wang, Shanlong Han, Pu Wang, Qinghua Zhang, Guibin Jiang. Distribution of polychlorinated biphenyls in an urban riparian zone affected by wastewater treatment plant effluent and the transfer to terrestrial compartment by invertebrates.
The Science of the total environment.
2013 Oct; 463-464(?):252-7. doi:
10.1016/j.scitotenv.2013.06.006. [PMID: 23811358] - Helena Bjermo, Per Ola Darnerud, Sanna Lignell, Monika Pearson, Panu Rantakokko, Cecilia Nälsén, Heléne Enghardt Barbieri, Hannu Kiviranta, Anna Karin Lindroos, Anders Glynn. Fish intake and breastfeeding time are associated with serum concentrations of organochlorines in a Swedish population.
Environment international.
2013 Jan; 51(?):88-96. doi:
10.1016/j.envint.2012.10.010. [PMID: 23201820] - Thomas Schettgen, A Alt, D Preim, D Keller, T Kraus. Biological monitoring of indoor-exposure to dioxin-like and non-dioxin-like polychlorinated biphenyls (PCB) in a public building.
Toxicology letters.
2012 Aug; 213(1):116-21. doi:
10.1016/j.toxlet.2011.06.005. [PMID: 21699966] - Sophie Bourez, Soazig Le Lay, Carine Van den Daelen, Caroline Louis, Yvan Larondelle, Jean-Pierre Thomé, Yves-Jacques Schneider, Isabelle Dugail, Cathy Debier. Accumulation of polychlorinated biphenyls in adipocytes: selective targeting to lipid droplets and role of caveolin-1.
PloS one.
2012; 7(2):e31834. doi:
10.1371/journal.pone.0031834. [PMID: 22363745] - Edward F Fitzgerald, Srishti Shrestha, Patrick M Palmer, Lloyd R Wilson, Erin E Belanger, Marta I Gomez, Michael R Cayo, Syni-An Hwang. Polychlorinated biphenyls (PCBs) in indoor air and in serum among older residents of upper Hudson River communities.
Chemosphere.
2011 Sep; 85(2):225-31. doi:
10.1016/j.chemosphere.2011.06.027. [PMID: 21724230] - Michel Aubé, Christian Larochelle, Pierre Ayotte. Differential effects of a complex organochlorine mixture on the proliferation of breast cancer cell lines.
Environmental research.
2011 Apr; 111(3):337-47. doi:
10.1016/j.envres.2011.01.010. [PMID: 21295777] - Jordi Sunyer, Raquel Garcia-Esteban, Mar Alvarez, Mònica Guxens, Fernando Goñi, Mikel Basterrechea, Martine Vrijheid, Stefano Guerra, Josep M Antó. DDE in mothers' blood during pregnancy and lower respiratory tract infections in their infants.
Epidemiology (Cambridge, Mass.).
2010 Sep; 21(5):729-35. doi:
10.1097/ede.0b013e3181e5ea96. [PMID: 20616741] - Valeria Tigini, Valeria Prigione, Sara Di Toro, Fabio Fava, Giovanna C Varese. Isolation and characterisation of polychlorinated biphenyl (PCB) degrading fungi from a historically contaminated soil.
Microbial cell factories.
2009 Jan; 8(?):5. doi:
10.1186/1475-2859-8-5. [PMID: 19138404] - Milena Cerná, Marek Malý, Roman Grabic, Andrea Batáriová, Jirí Smíd, Bohuslav Benes. Serum concentrations of indicator PCB congeners in the Czech adult population.
Chemosphere.
2008 Jul; 72(8):1124-31. doi:
10.1016/j.chemosphere.2008.04.019. [PMID: 18547604] - Xuemei Li, Qinghua Zhang, Jiayin Dai, Yiping Gan, Jun Zhou, Xiangping Yang, Hong Cao, Guibin Jiang, Muqi Xu. Pesticide contamination profiles of water, sediment and aquatic organisms in the effluent of Gaobeidian wastewater treatment plant.
Chemosphere.
2008 Jul; 72(8):1145-51. doi:
10.1016/j.chemosphere.2008.03.049. [PMID: 18472141] - Stuart Harrad, Matthew Robson, Sadegh Hazrati, Victoria S Baxter-Plant, Kevin Deplanche, Mark D Redwood, Lynne E Macaskie. Dehalogenation of polychlorinated biphenyls and polybrominated diphenyl ethers using a hybrid bioinorganic catalyst.
Journal of environmental monitoring : JEM.
2007 Apr; 9(4):314-8. doi:
10.1039/b616567b. [PMID: 17410306] - Mike Howsam, Joan O Grimalt, Elisabet Guinó, Matilde Navarro, Juan Martí-Ragué, Miguel A Peinado, Gabriel Capellá, Victor Moreno. Organochlorine exposure and colorectal cancer risk.
Environmental health perspectives.
2004 Nov; 112(15):1460-6. doi:
10.1289/ehp.7143. [PMID: 15531428] - T P Twaroski, M L O'Brien, N Larmonier, H P Glauert, L W Robertson. Polychlorinated biphenyl-induced effects on metabolic enzymes, AP-1 binding, vitamin E, and oxidative stress in the rat liver.
Toxicology and applied pharmacology.
2001 Mar; 171(2):85-93. doi:
10.1006/taap.2000.9114. [PMID: 11222084] - B J Connell, A Singh, I Chu. Toxicity of PCB 28 in the rat liver: a quantitative ultrastructural study.
Journal of submicroscopic cytology and pathology.
2001 Jan; 33(1-2):41-6. doi:
". [PMID: 11686407] - D Desaulniers, R Poon, W Phan, K Leingartner, W G Foster, I Chu. Reproductive and thyroid hormone levels in rats following 90-day dietary exposure to PCB 28 (2,4,4'-trichlorobiphenyl) or PCB 77 (3,3'4,4'-tetrachlorobiphenyl).
Toxicology and industrial health.
1997 Sep; 13(5):627-38. doi:
10.1177/074823379701300504. [PMID: 9284533] - I Chu, D C Villeneuve, A Yagminas, P Lecavalier, R Poon, H Håkansson, U G Ahlborg, V E Valli, S W Kennedy, A Bergman, R F Seegal, M Feeley. Toxicity of 2,4,4'-trichlorobiphenyl in rats following 90-day dietary exposure.
Journal of toxicology and environmental health.
1996 Oct; 49(3):301-18. doi:
10.1080/00984108.1996.11667603. [PMID: 8876656] - D Moir, A Viau, I Chu, E K Wehler, A Mörck, A Bergman. Tissue distribution, metabolism, and excretion of 2,4,4'-trichlorobiphenyl (CB-28) in the rat.
Toxicology and industrial health.
1996 Jan; 12(1):105-21. doi:
10.1177/074823379601200107. [PMID: 8713718] - D K Ness, S L Schantz, J Moshtaghian, L G Hansen. Effects of perinatal exposure to specific PCB congeners on thyroid hormone concentrations and thyroid histology in the rat.
Toxicology letters.
1993 Jun; 68(3):311-23. doi:
10.1016/0378-4274(93)90023-q. [PMID: 8516785] - J Yudkin, R D Cohen, B Slack. The haemodynamic effects of metabolic acidosis in the rat.
Clinical science and molecular medicine.
1976 Mar; 50(3):177-84. doi:
10.1042/cs0500177. [PMID: 3306]