Vinyl carbamate (BioDeep_00000275639)
代谢物信息卡片
化学式: C3H5NO2 (87.032)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C=COC(=N)O
InChI: InChI=1S/C3H5NO2/c1-2-6-3(4)5/h2H,1H2,(H2,4,5)
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:27292
- PubChem: 27492
- CAS: 15805-73-9
- MoNA: FiehnHILIC000854
- PMhub: MS000008452
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Tadashi Honda, Hidenori Yoshizawa, Chitra Sundararajan, Emilie David, Marc J Lajoie, Frank G Favaloro, Tomasz Janosik, Xiaobo Su, Yukiko Honda, Bill D Roebuck, Gordon W Gribble. Tricyclic compounds containing nonenolizable cyano enones. A novel class of highly potent anti-inflammatory and cytoprotective agents.
Journal of medicinal chemistry.
2011 Mar; 54(6):1762-78. doi:
10.1021/jm101445p
. [PMID: 21361338] - A A Oyagbemi, A B Saba, O I Azeez. Capsaicin: a novel chemopreventive molecule and its underlying molecular mechanisms of action.
Indian journal of cancer.
2010 Jan; 47(1):53-8. doi:
10.4103/0019-509x.58860
. [PMID: 20071791] - Ganesh Shanmugam, Ivan D Kozekov, F Peter Guengerich, Carmelo J Rizzo, Michael P Stone. Structure of the 1,N2-ethenodeoxyguanosine adduct opposite cytosine in duplex DNA: Hoogsteen base pairing at pH 5.2.
Chemical research in toxicology.
2008 Sep; 21(9):1795-805. doi:
10.1021/tx8001466
. [PMID: 18693701] - Preetha Anand, Ajaikumar B Kunnumakkara, Ajaikumar B Kunnumakara, Chitra Sundaram, Kuzhuvelil B Harikumar, Sheeja T Tharakan, Oiki S Lai, Bokyung Sung, Bharat B Aggarwal. Cancer is a preventable disease that requires major lifestyle changes.
Pharmaceutical research.
2008 Sep; 25(9):2097-116. doi:
10.1007/s11095-008-9661-9
. [PMID: 18626751] - Sujata Choudhury, Sanjay Adhikari, Amrita Cheema, Rabindra Roy. Evidence of complete cellular repair of 1,N6-ethenoadenine, a mutagenic and potential damage for human cancer, revealed by a novel method.
Molecular and cellular biochemistry.
2008 Jun; 313(1-2):19-28. doi:
10.1007/s11010-008-9737-1
. [PMID: 18373235] - Lya G Hernandez, Poh-Gek Forkert. In vivo mutagenicity of vinyl carbamate and ethyl carbamate in lung and small intestine of F1 (Big Blue x A/J) transgenic mice.
International journal of cancer.
2007 Apr; 120(7):1426-33. doi:
10.1002/ijc.22502
. [PMID: 17205523] - Alain Barbin, Rong Wang, Peter J O'Connor, Rhoderick H Elder. Increased formation and persistence of 1,N(6)-ethenoadenine in DNA is not associated with higher susceptibility to carcinogenesis in alkylpurine-DNA-N-glycosylase knockout mice treated with vinyl carbamate.
Cancer research.
2003 Nov; 63(22):7699-703. doi:
"
. [PMID: 14633693] - Y J Surh, S G Kim, K K Park, Y Sohn, J M Lee, N D Kim, J A Miller. Chemopreventive effects of 2-(allylthio)pyrazine on hepatic lesion, mutagenesis and tumorigenesis induced by vinyl carbamate or vinyl carbamate epoxide.
Carcinogenesis.
1998 Jul; 19(7):1263-7. doi:
10.1093/carcin/19.7.1263
. [PMID: 9683187] - S G Kim, Y J Surh, Y Sohn, J K Yoo, J W Lee, A Liem, J A Miller. Inhibition of vinyl carbamate-induced hepatotoxicity, mutagenicity, and tumorigenicity by isopropyl-2-(1,3-dithietane-2-ylidene)-2-[N-(4-methylthiazol-2- yl)carbamoyl]acetate (YH439).
Carcinogenesis.
1998 Apr; 19(4):687-90. doi:
10.1093/carcin/19.4.687
. [PMID: 9600356] - K K Park, A Liem, B C Stewart, J A Miller. Vinyl carbamate epoxide, a major strong electrophilic, mutagenic and carcinogenic metabolite of vinyl carbamate and ethyl carbamate (urethane).
Carcinogenesis.
1993 Mar; 14(3):441-50. doi:
10.1093/carcin/14.3.441
. [PMID: 8453720] - J A Campbell, C F Eppersimons, A D Kligerman, A B Petro, Y Sharief, J W Allen. Sister chromatid exchange analysis in cultured primary lung, liver, and kidney cells of mice following in vivo exposure to vinyl carbamate.
In vitro cellular & developmental biology : journal of the Tissue Culture Association.
1986 Aug; 22(8):443-8. doi:
10.1007/bf02623444
. [PMID: 3733639]