BENACTYZINE (BioDeep_00000275562)

   


代谢物信息卡片


BENACTYZINE

化学式: C20H25NO3 (327.18343400000003)
中文名称: 胃复康
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCN(CC)CCOC(=O)C(C1=CC=CC=C1)(C2=CC=CC=C2)O
InChI: InChI=1S/C20H25NO3/c1-3-21(4-2)15-16-24-19(22)20(23,17-11-7-5-8-12-17)18-13-9-6-10-14-18/h5-14,23H,3-4,15-16H2,1-2H3

描述信息

C78272 - Agent Affecting Nervous System > C66880 - Anticholinergic Agent > C29704 - Antimuscarinic Agent
D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010276 - Parasympatholytics
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D018680 - Cholinergic Antagonists

同义名列表

1 个代谢物同义名

BENACTYZINE



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • E Bodur, A N Cokuğraş, E F Tezcan. Inhibition effects of benactyzine and drofenine on human serum butyrylcholinesterase. Archives of biochemistry and biophysics. 2001 Feb; 386(1):25-9. doi: 10.1006/abbi.2000.2188. [PMID: 11360997]
  • G Vargas, J Havel, L Babácková, J Patocka. Determination of drugs used as anti-Parkinson's disease drugs in urine and serum by capillary electrophoresis. Journal of capillary electrophoresis. 1998 May; 5(3-4):153-8. doi: . [PMID: 10797881]
  • J Kassa. Importance of cholinolytic drug selection for the efficacy of HI-6 against soman in rats. Toxicology. 1997 Jan; 116(1-3):147-52. doi: 10.1016/s0300-483x(96)03537-8. [PMID: 9020515]
  • J Kassa. [Comparison of the effect of HI-6 oxime and its derivatives in combination with benactyzine on cholinergic and stress effects of soman in rats]. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti. 1996 May; 45(3):149-53. doi: . [PMID: 8696692]
  • J Kassa, J Bajgar. The influence of pharmacological pretreatment on efficacy of HI-6 oxime in combination with benactyzine in soman poisoning in rats. Human & experimental toxicology. 1996 May; 15(5):383-8. doi: 10.1177/096032719601500503. [PMID: 8735460]
  • J Kassa, J Bajgar. [Comparison of the effect of selected anticholinergic agents on cholinergic and noncholinergic effects of GV substances during acute poisoning in rats]. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti. 1994 Oct; 43(5):222-5. doi: NULL. [PMID: 7982005]
  • O I Shushliapin, L G Kononenko, L K Bakhova, S A Koroza, A N Shelest. [Biological age, adrenoreception and lipid peroxidation in patients with ischemic heart disease]. Likars'ka sprava. 1993 Oct; ?(10-12):39-42. doi: ". [PMID: 8030305]
  • T Mirkhaitov, L T Ikramov. [The detection of amizil in studying different objects]. Sudebno-meditsinskaia ekspertiza. 1991 Jan; 34(1):38-40. doi: NULL. [PMID: 1858119]
  • P V Vaĭnauskas. [An evaluation of methods for isolating antiparkinson preparations from cadaveric material]. Sudebno-meditsinskaia ekspertiza. 1990 Jan; 33(1):40-1. doi: NULL. [PMID: 2336668]
  • N N Beller, I I Busygina. [Effect of stimulation of the amygdaloid body on water-excretory function of the kidneys]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. 1982 Apr; 68(4):503-7. doi: NULL. [PMID: 7084514]
  • W Hauser, N Weger. Therapeutic effects of the bis-pyridinium salts HGG-12, HGG-42, and atropine, benactyzine in organophosphate poisoning of dogs. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement. 1979; ?(2):393-6. doi: 10.1007/978-3-642-67265-1_44. [PMID: 288351]
  • V N El'skiĭ. [Effect of amisyl on the hypothalamo-hypophyseal-adrenal system in the dynamics of shock caused by prolonged crushing of the soft tissues]. Anesteziologiia i reanimatologiia. 1977 May; ?(3):50-3. doi: NULL. [PMID: 889135]
  • C White, E Doyle, L F Chasseaud, T Taylor. Serum concentrations of methaqualone after repeated oral doses of a combination formulation to human subjects. European journal of clinical pharmacology. 1976 Sep; 10(5):343-7. doi: 10.1007/bf00565624. [PMID: 10165]
  • J Schenk, W Löffler, N Weger. Therapeutic effects of HS-3, HS-6, benactyzine, and atropine in soman poisoning of dogs. Archives of toxicology. 1976 Sep; 36(1):71-81. doi: 10.1007/bf00277565. [PMID: 989716]
  • J Bajgar, J Patocka, J Fusek, J Herink, V Hrdina. Proceedings: Some factors influencing the effects of benactyzine. Activitas nervosa superior. 1974; 16(4):253. doi: NULL. [PMID: 4450999]
  • P P Denisenko, R P Cherednichenko. [M-cholinoreactive biochemical systems and formation of serum antibodies]. Biulleten' eksperimental'noi biologii i meditsiny. 1972 Apr; 73(4):65-8. doi: NULL. [PMID: 5029452]
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  • J Bajgar, J Patocka. The binding of benactyzine to human serum albumin. Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove. 1970; 13(4):363-70. doi: NULL. [PMID: 5286024]
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  • V M Banshchikov, G V Stoliarov. [Psychotomimetic drugs with anticholinergic effects]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952). 1966; 66(3):464-8. doi: NULL. [PMID: 6000446]
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