2-AMINOPYRIDINE (BioDeep_00000275421)

   

Volatile Flavor Compounds


代谢物信息卡片


2-AMINOPYRIDINE

化学式: C5H6N2 (94.05309559999999)
中文名称: 2-氨基吡啶
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=NC(=C1)N
InChI: InChI=1S/C5H6N2/c6-5-3-1-2-4-7-5/h1-4H,(H2,6,7)

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
D004396 - Coloring Agents > D005456 - Fluorescent Dyes
CONFIDENCE standard compound; INTERNAL_ID 2438
CONFIDENCE standard compound; INTERNAL_ID 8012

同义名列表

2 个代谢物同义名

2-AMINOPYRIDINE; 2-Aminopyridine



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Garrick P Smith, Lassina Badolo, Victoria Chell, I-Jen Chen, Kenneth Vielsted Christensen, Laurent David, Justus Alfred Daechsel, Morten Hentzer, Martin Christian Herzig, Gitte Kobberøe Mikkelsen, Stephen P Watson, Douglas S Williamson. The design and SAR of a novel series of 2-aminopyridine based LRRK2 inhibitors. Bioorganic & medicinal chemistry letters. 2017 09; 27(18):4500-4505. doi: 10.1016/j.bmcl.2017.07.072. [PMID: 28802631]
  • Heng-Yen Wang, Yajuan Qin, Huiying Li, Linda J Roman, Pavel Martásek, Thomas L Poulos, Richard B Silverman. Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker. Journal of medicinal chemistry. 2016 05; 59(10):4913-25. doi: 10.1021/acs.jmedchem.6b00273. [PMID: 27050842]
  • Shuyi Wang, Hideyuki Takahashi, Hiroyuki Kajiura, Taiji Kawakatsu, Kazuhito Fujiyama, Fumio Takaiwa. Transgenic rice seeds accumulating recombinant hypoallergenic birch pollen allergen Bet v 1 generate giant protein bodies. Plant & cell physiology. 2013 Jun; 54(6):917-33. doi: 10.1093/pcp/pct043. [PMID: 23539245]
  • Daniele Sanna, Péter Buglyó, Ana Isabel Tomaz, João Costa Pessoa, Slađana Borović, Giovanni Micera, Eugenio Garribba. V(IV)O and Cu(II) complexation by ligands based on pyridine nitrogen donors. Dalton transactions (Cambridge, England : 2003). 2012 Nov; 41(41):12824-38. doi: 10.1039/c2dt31109g. [PMID: 22975792]
  • Duraisamy Senthil Raja, Nattamai S P Bhuvanesh, Karuppannan Natarajan. A novel water soluble ligand bridged cobalt(II) coordination polymer of 2-oxo-1,2-dihydroquinoline-3-carbaldehyde (isonicotinic) hydrazone: evaluation of the DNA binding, protein interaction, radical scavenging and anticancer activity. Dalton transactions (Cambridge, England : 2003). 2012 Apr; 41(15):4365-77. doi: 10.1039/c2dt12274j. [PMID: 22354161]
  • Fabien Caillé, Célia S Bonnet, Frédéric Buron, Sandrine Villette, Lothar Helm, Stéphane Petoud, Franck Suzenet, Eva Tóth. Isoquinoline-based lanthanide complexes: bright NIR optical probes and efficient MRI agents. Inorganic chemistry. 2012 Feb; 51(4):2522-32. doi: 10.1021/ic202446e. [PMID: 22233349]
  • Samuel Estrada-Soto, Amanda Sánchez-Recillas, Gabriel Navarrete-Vázquez, Patricia Castillo-España, Rafael Villalobos-Molina, Maximiliano Ibarra-Barajas. Relaxant effects of Artemisia ludoviciana on isolated rat smooth muscle tissues. Journal of ethnopharmacology. 2012 Jan; 139(2):513-8. doi: 10.1016/j.jep.2011.11.041. [PMID: 22155473]
  • Linda Wildling, Christian Rankl, Thomas Haselgrübler, Hermann J Gruber, Marion Holy, Amy Hauck Newman, Mu-Fa Zou, Rong Zhu, Michael Freissmuth, Harald H Sitte, Peter Hinterdorfer. Probing binding pocket of serotonin transporter by single molecular force spectroscopy on living cells. The Journal of biological chemistry. 2012 Jan; 287(1):105-113. doi: 10.1074/jbc.m111.304873. [PMID: 22033932]
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  • Sarkar M A Kawsar, Ryo Matsumoto, Yuki Fujii, Haruki Matsuoka, Naoko Masuda, Iwahara Chihiro, Hidetaro Yasumitsu, Robert A Kanaly, Shigeki Sugawara, Masahiro Hosono, Kazuo Nitta, Naoto Ishizaki, Chikaku Dogasaki, Jiharu Hamako, Taei Matsui, Yasuhiro Ozeki. Cytotoxicity and glycan-binding profile of a D-galactose-binding lectin from the eggs of a Japanese sea hare (Aplysia kurodai). The protein journal. 2011 Oct; 30(7):509-19. doi: 10.1007/s10930-011-9356-7. [PMID: 21953532]
  • Xiangdong Su, Fabienne Pradaux-Caggiano, Nigel Vicker, Mark P Thomas, Heather Halem, Michael D Culler, Barry V L Potter. Adamantyl ethanone pyridyl derivatives: potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1. ChemMedChem. 2011 Sep; 6(9):1616-29. doi: 10.1002/cmdc.201100182. [PMID: 21714097]
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  • Masahiro Yodoshi, Takehiro Oyama, Ken Masaki, Kazuaki Kakehi, Takao Hayakawa, Shigeo Suzuki. Affinity entrapment of oligosaccharides and glycopeptides using free lectin solution. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2011; 27(4):395. doi: 10.2116/analsci.27.395. [PMID: 21478615]
  • Samuel Estrada-Soto, Julio Rivera-Leyva, Juan José Ramírez-Espinosa, Patricia Castillo-España, Francisco Aguirre-Crespo, Oswaldo Hernández-Abreu. Vasorelaxant effect of Valeriana edulis ssp. procera (Valerianaceae) and its mode of action as calcium channel blocker. The Journal of pharmacy and pharmacology. 2010 Sep; 62(9):1167-74. doi: 10.1111/j.2042-7158.2010.01146.x. [PMID: 20796196]
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  • Yoshio Araki, Kenichi Mukaisho, Hiroyuki Sugihara, Yoshihide Fujiyama, Takanori Hattori. Proteus mirabilis sp. intestinal microflora grow in a dextran sulfate sodium-rich environment. International journal of molecular medicine. 2010 Feb; 25(2):203-8. doi: 10.3892/ijmm_00000331. [PMID: 20043128]
  • Sumihiro Hase. Pyridylamination as a means of analyzing complex sugar chains. Proceedings of the Japan Academy. Series B, Physical and biological sciences. 2010; 86(4):378-90. doi: 10.2183/pjab.86.378. [PMID: 20431262]
  • Chika Wakita, Takuya Maeshima, Atsushi Yamazaki, Takahiro Shibata, Sohei Ito, Mitsugu Akagawa, Makoto Ojika, Junji Yodoi, Koji Uchida. Stereochemical configuration of 4-hydroxy-2-nonenal-cysteine adducts and their stereoselective formation in a redox-regulated protein. The Journal of biological chemistry. 2009 Oct; 284(42):28810-22. doi: 10.1074/jbc.m109.019927. [PMID: 19692331]
  • Isabella Rustighi, Cristiana Campa, Marco Rossi, Sabrina Semeraro, Amedeo Vetere, Amelia Gamini. Analysis of N-acetylaminosugars by CE: a comparative derivatization study. Electrophoresis. 2009 Aug; 30(15):2632-9. doi: 10.1002/elps.200800791. [PMID: 19621375]
  • Oswaldo Hernández-Abreu, Patricia Castillo-España, Ismael León-Rivera, Maximiliano Ibarra-Barajas, Rafael Villalobos-Molina, Judith González-Christen, Jorge Vergara-Galicia, Samuel Estrada-Soto. Antihypertensive and vasorelaxant effects of tilianin isolated from Agastache mexicana are mediated by NO/cGMP pathway and potassium channel opening. Biochemical pharmacology. 2009 Jul; 78(1):54-61. doi: 10.1016/j.bcp.2009.03.016. [PMID: 19447223]
  • Makoto Ogata, Makoto Nakajima, Tatsuya Kato, Takakiyo Obara, Hirokazu Yagi, Koichi Kato, Taichi Usui, Enoch Y Park. Synthesis of sialoglycopolypeptide for potentially blocking influenza virus infection using a rat alpha2,6-sialyltransferase expressed in BmNPV bacmid-injected silkworm larvae. BMC biotechnology. 2009 Jun; 9(?):54. doi: 10.1186/1472-6750-9-54. [PMID: 19500344]
  • Kazuhiro Tanabe, Akihiro Deguchi, Mikito Higashi, Hisashi Usuki, Yasuyuki Suzuki, Youichi Uchimura, Shigeki Kuriyama, Kazuhiro Ikenaka. Outer arm fucosylation of N-glycans increases in sera of hepatocellular carcinoma patients. Biochemical and biophysical research communications. 2008 Sep; 374(2):219-25. doi: 10.1016/j.bbrc.2008.06.124. [PMID: 18619944]
  • Jorge Vergara-Galicia, Rolffy Ortiz-Andrade, Patricia Castillo-España, Maximiliano Ibarra-Barajas, Itzell Gallardo-Ortiz, Rafael Villalobos-Molina, Samuel Estrada-Soto. Antihypertensive and vasorelaxant activities of Laelia autumnalis are mainly through calcium channel blockade. Vascular pharmacology. 2008 Jul; 49(1):26-31. doi: 10.1016/j.vph.2008.04.002. [PMID: 18534917]
  • Daniel Kolarich, Alfred Weber, Martin Pabst, Johannes Stadlmann, Wolfgang Teschner, Hartmut Ehrlich, Hans-Peter Schwarz, Friedrich Altmann. Glycoproteomic characterization of butyrylcholinesterase from human plasma. Proteomics. 2008 Jan; 8(2):254-63. doi: 10.1002/pmic.200700720. [PMID: 18203274]
  • Yonnie Wu, Richard C Laughlin, David C Henry, Darryl E Krueger, JoAn S Hudson, Cheng-Yi Kuan, Jian He, Jason Reppert, Jeffrey P Tomkins. Naturally occurring and stress induced tubular structures from mammalian cells, a survival mechanism. BMC cell biology. 2007 Aug; 8(?):36. doi: 10.1186/1471-2121-8-36. [PMID: 17705822]
  • Stephen P Muench, Sean T Prigge, Rima McLeod, John B Rafferty, Michael J Kirisits, Craig W Roberts, Ernest J Mui, David W Rice. Studies of Toxoplasma gondii and Plasmodium falciparum enoyl acyl carrier protein reductase and implications for the development of antiparasitic agents. Acta crystallographica. Section D, Biological crystallography. 2007 Mar; 63(Pt 3):328-38. doi: 10.1107/s0907444906053625. [PMID: 17327670]
  • Jinghua Qian, Ann H West, Paul F Cook. Acid-base chemical mechanism of homocitrate synthase from Saccharomyces cerevisiae. Biochemistry. 2006 Oct; 45(39):12136-43. doi: 10.1021/bi060889h. [PMID: 17002313]
  • Yasuhiro Takegawa, Kisaburo Deguchi, Takuro Keira, Hiroki Ito, Hiroaki Nakagawa, Shin-Ichiro Nishimura. Separation of isomeric 2-aminopyridine derivatized N-glycans and N-glycopeptides of human serum immunoglobulin G by using a zwitterionic type of hydrophilic-interaction chromatography. Journal of chromatography. A. 2006 Apr; 1113(1-2):177-81. doi: 10.1016/j.chroma.2006.02.010. [PMID: 16503336]
  • Cristiano Ruch Werneck Guimarães, Dale L Boger, William L Jorgensen. Elucidation of fatty acid amide hydrolase inhibition by potent alpha-ketoheterocycle derivatives from Monte Carlo simulations. Journal of the American Chemical Society. 2005 Dec; 127(49):17377-84. doi: 10.1021/ja055438j. [PMID: 16332087]
  • Megumi Maeda, Maiko Kamamoto, Katsuhiko Hino, Shigeto Yamamoto, Mariko Kimura, Mitsuhiro Okano, Yoshinobu Kimura. Glycoform analysis of Japanese cedar pollen allergen, Cry j 1. Bioscience, biotechnology, and biochemistry. 2005 Sep; 69(9):1700-5. doi: 10.1271/bbb.69.1700. [PMID: 16195587]
  • Kwan Kit Woo, Yoshinobu Kimura. Regulation of substrate specificity of plant alpha-mannosidase by cobalt ion: in vitro hydrolysis of high-mannose type N-glycans by Co2+-activated Ginkgo alpha-mannosidase. Bioscience, biotechnology, and biochemistry. 2005 Jun; 69(6):1111-9. doi: 10.1271/bbb.69.1111. [PMID: 15973042]
  • Yasuhiro Takegawa, Kisaburo Deguchi, Shinya Ito, Shinji Yoshioka, Hiroaki Nakagawa, Shin-Ichiro Nishimura. Simultaneous analysis of 2-aminopyridine-derivatized neutral and sialylated oligosaccharides from human serum in the negative-ion mode by sonic spray ionization ion trap mass spectrometry. Analytical chemistry. 2005 Apr; 77(7):2097-106. doi: 10.1021/ac048499t. [PMID: 15801743]
  • Yoshinobu Kimura, Maiko Kamamoto, Megumi Maeda, Mitsuhiro Okano, Minehiko Yokoyama, Kosuke Kino. Occurrence of Lewis a epitope in N-glycans of a glycoallergen, Jun a 1, from mountain cedar (Juniperus ashei) pollen. Bioscience, biotechnology, and biochemistry. 2005 Jan; 69(1):137-44. doi: 10.1271/bbb.69.137. [PMID: 15665478]
  • Takeshi Ishimizu, Akiko Sasaki, Satoshi Okutani, Mami Maeda, Mai Yamagishi, Sumihiro Hase. Endo-beta-mannosidase, a plant enzyme acting on N-glycan: purification, molecular cloning, and characterization. The Journal of biological chemistry. 2004 Sep; 279(37):38555-62. doi: 10.1074/jbc.m406886200. [PMID: 15247239]
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