2-Aminobiphenyl (BioDeep_00000275420)
代谢物信息卡片
2-Aminobiphenyl
化学式: C12H11N (169.0891446)
中文名称: 2-氨基联苯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)C2=CC=CC=C2N
InChI: InChI=1S/C12H11N/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9H,13H2
描述信息
CONFIDENCE standard compound; INTERNAL_ID 8010
同义名列表
2 个代谢物同义名
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lori M Millner, Mark A Doll, Jian Cai, J Christopher States, David W Hein. NATb/NAT1*4 promotes greater arylamine N-acetyltransferase 1 mediated DNA adducts and mutations than NATa/NAT1*4 following exposure to 4-aminobiphenyl.
Molecular carcinogenesis.
2012 Aug; 51(8):636-46. doi:
10.1002/mc.20836. [PMID: 21837760] - Jae-In Yoon, Sang-In Kim, Stella Tommasi, Ahmad Besaratinia. Organ specificity of the bladder carcinogen 4-aminobiphenyl in inducing DNA damage and mutation in mice.
Cancer prevention research (Philadelphia, Pa.).
2012 Feb; 5(2):299-308. doi:
10.1158/1940-6207.capr-11-0309. [PMID: 22086680] - Joseph D Paonessa, Yi Ding, Kristen L Randall, Rex Munday, Dayana Argoti, Paul Vouros, Yuesheng Zhang. Identification of an unintended consequence of Nrf2-directed cytoprotection against a key tobacco carcinogen plus a counteracting chemopreventive intervention.
Cancer research.
2011 Jun; 71(11):3904-11. doi:
10.1158/0008-5472.can-11-0396. [PMID: 21487034] - Tiffany H Seyler, John T Bernert. Analysis of 4-aminobiphenyl in smoker's and nonsmoker's urine by tandem mass spectrometry.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2011 May; 16(3):212-21. doi:
10.3109/1354750x.2010.544755. [PMID: 21438718] - Thomas Schettgen, K Heinrich, T Kraus, Monika Gube. Determination of 2,5-toluylenediamine (2,5-TDA) and aromatic amines in urine after personal application of hair dyes: kinetics and doses.
Archives of toxicology.
2011 Feb; 85(2):127-33. doi:
10.1007/s00204-010-0563-3. [PMID: 20549195] - Tiffany H Seyler, Levi-Rose Reyes, John T Bernert. Analysis of 4-aminobiphenyl hemoglobin adducts in smokers and nonsmokers by pseudo capillary on-column gas chromatography- tandem mass spectrometry.
Journal of analytical toxicology.
2010 Jul; 34(6):304-11. doi:
10.1093/jat/34.6.304. [PMID: 20663282] - Mieke J J Van Hemelrijck, Dominique S Michaud, Gregory N Connolly, Zubair Kabir. Secondhand smoking, 4-aminobiphenyl, and bladder cancer: two meta-analyses.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2009 Apr; 18(4):1312-20. doi:
10.1158/1055-9965.epi-08-0613. [PMID: 19336562] - Erin E Bessette, Angela K Goodenough, Sophie Langouët, Isil Yasa, Ivan D Kozekov, Simon D Spivack, Robert J Turesky. Screening for DNA adducts by data-dependent constant neutral loss-triple stage mass spectrometry with a linear quadrupole ion trap mass spectrometer.
Analytical chemistry.
2009 Jan; 81(2):809-19. doi:
10.1021/ac802096p. [PMID: 19086795] - David W Hein, Jean Bendaly, Jason R Neale, Mark A Doll. Systemic functional expression of N-acetyltransferase polymorphism in the F344 Nat2 congenic rat.
Drug metabolism and disposition: the biological fate of chemicals.
2008 Dec; 36(12):2452-9. doi:
10.1124/dmd.108.023960. [PMID: 18799801] - Vikas Kumar, Chandrajeetbalo Majumdar, Partha Roy. Effects of endocrine disrupting chemicals from leather industry effluents on male reproductive system.
The Journal of steroid biochemistry and molecular biology.
2008 Sep; 111(3-5):208-16. doi:
10.1016/j.jsbmb.2008.06.005. [PMID: 18606229] - J W M Yuen, M D I Gohel. The dual roles of Ganoderma antioxidants on urothelial cell DNA under carcinogenic attack.
Journal of ethnopharmacology.
2008 Jul; 118(2):324-30. doi:
10.1016/j.jep.2008.05.003. [PMID: 18550308] - Bernhard Setzer, Dirk Lebrecht, Ulrich A Walker. Pyrimidine nucleoside depletion sensitizes to the mitochondrial hepatotoxicity of the reverse transcriptase inhibitor stavudine.
The American journal of pathology.
2008 Mar; 172(3):681-90. doi:
10.2353/ajpath.2008.070613. [PMID: 18276780] - Patrudu Makena, King-Thom Chung. Evidence that 4-aminobiphenyl, benzidine, and benzidine congeners produce genotoxicity through reactive oxygen species.
Environmental and molecular mutagenesis.
2007 Jun; 48(5):404-13. doi:
10.1002/em.20288. [PMID: 17370336] - Kirsten Riedel, Gerhard Scherer, Johannes Engl, Heinz-Werner Hagedorn, Anthony R Tricker. Determination of three carcinogenic aromatic amines in urine of smokers and nonsmokers.
Journal of analytical toxicology.
2006 Apr; 30(3):187-95. doi:
10.1093/jat/30.3.187. [PMID: 16803653] - Qing-Yi Lu, Yu-Sheng Jin, Allan Pantuck, Zuo-Feng Zhang, David Heber, Arie Belldegrun, Mai Brooks, Robert Figlin, Jianyu Rao. Green tea extract modulates actin remodeling via Rho activity in an in vitro multistep carcinogenic model.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2005 Feb; 11(4):1675-83. doi:
10.1158/1078-0432.ccr-04-1608. [PMID: 15746073] - J Esteban Castelao, Jian-Min Yuan, Manuela Gago-Dominguez, Paul L Skipper, Steven R Tannenbaum, Kenneth K Chan, Mary A Watson, Douglas A Bell, Gerhard A Coetzee, Ronald K Ross, Mimi C Yu. Carotenoids/vitamin C and smoking-related bladder cancer.
International journal of cancer.
2004 Jun; 110(3):417-23. doi:
10.1002/ijc.20104. [PMID: 15095308] - Mirle Ferrer, Carles Cristófol, Angel Sánchez-Lamar, Jorge Luís Fuentes, Jordi Barbé, Montserrat Llagostera. Modulation of rat and human cytochromes P450 involved in PhIP and 4-ABP activation by an aqueous extract of Phyllanthus orbicularis.
Journal of ethnopharmacology.
2004 Feb; 90(2-3):273-7. doi:
10.1016/j.jep.2003.10.005. [PMID: 15013192] - Young H Ju, Michael J Plewa. Mutant spectra analysis at hisG46 in Salmonella typhimurium strain YG1029 induced by mammalian S9- and plant-activated aromatic amines.
Teratogenesis, carcinogenesis, and mutagenesis.
2003; Suppl 1(?):47-60. doi:
10.1002/tcm.10061. [PMID: 12616596] - Hui-Ming Chen, Tao Qin, Li-Xin Zhao, Xiao-Bai Xu. Effects of lead on 4-aminobiphenyl pharmacokinetics in liver, kidney, spleen, testes, heart, lung and hemoglobin adduct for rat model.
Ecotoxicology (London, England).
2002 Aug; 11(4):255-64. doi:
10.1023/a:1016396121312. [PMID: 12211698] - T Mori, K Imaida, S Tamano, M Sano, S Takahashi, M Asamoto, M Takeshita, H Ueda, T Shirai. Beef tallow, but not perilla or corn oil, promotion of rat prostate and intestinal carcinogenesis by 3,2'-dimethyl-4-aminobiphenyl.
Japanese journal of cancer research : Gann.
2001 Oct; 92(10):1026-33. doi:
10.1111/j.1349-7006.2001.tb01056.x. [PMID: 11676852] - S D Turner, H Tinwell, W Piegorsch, P Schmezer, J Ashby. The male rat carcinogens limonene and sodium saccharin are not mutagenic to male Big Blue rats.
Mutagenesis.
2001 Jul; 16(4):329-32. doi:
10.1093/mutage/16.4.329. [PMID: 11420401] - S D Jatoe, M Kajbaf, J W Gorrod. High-performance liquid chromatography with on-line radioactivity monitoring for metabolic studies of 2- and 4-[14C]aminobiphenyls.
Journal of chromatography.
1988 Jun; 442(?):394-400. doi:
10.1016/s0021-9673(00)94489-3. [PMID: 3417828] - M Kajbaf, J W Gorrod. Metabolism of [14C]2-aminobiphenyl in vivo by different species.
European journal of drug metabolism and pharmacokinetics.
1987 Oct; 12(4):285-90. doi:
10.1007/bf03189914. [PMID: 3449387] - R Harzmann, D Gericke, E Altenähr, K H Bichler. [Chemically induced transplantable carcinomas of the urinary bladder in dogs (author's transl)].
Urologia internationalis.
1980; 35(5):340-50. doi:
10.1159/000280346. [PMID: 7423679] - S SHIBATA. Improved technique of O-aminobiphenyl method for the determination of glucose in serum.
The Bulletin of the Yamaguchi Medical School.
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NULL. [PMID: 13988476]