Brolamfetamine (BioDeep_00000275295)

   


代谢物信息卡片


Brolamfetamine

化学式: C11H16BrNO2 (273.0364336)
中文名称: 布苯丙胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(CC1=CC(=C(C=C1OC)Br)OC)N
InChI: InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3

描述信息

D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists
D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D006213 - Hallucinogens
C78272 - Agent Affecting Nervous System > C47794 - Serotonin Agonist

同义名列表

1 个代谢物同义名

Brolamfetamine



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Katerina Beránková, Miroslava Szkutová, Marie Balíková. Distribution profile of 2,5-dimethoxy-4-bromoamphetamine (DOB) in rats after oral and subcutaneous doses. Forensic science international. 2007 Aug; 170(2-3):94-9. doi: 10.1016/j.forsciint.2007.03.023. [PMID: 17629428]
  • Andreas H Ewald, Giselher Fritschi, Wolf-Rainer Bork, Hans H Maurer. Designer drugs 2,5-dimethoxy-4-bromo-amphetamine (DOB) and 2,5-dimethoxy-4-bromo-methamphetamine (MDOB): studies on their metabolism and toxicological detection in rat urine using gas chromatographic/mass spectrometric techniques. Journal of mass spectrometry : JMS. 2006 Apr; 41(4):487-98. doi: 10.1002/jms.1007. [PMID: 16470568]
  • Katerina Beránková, Marie Balíková. Study on metabolites of 2,5-dimethoxy-4-bromamphetamine (DOB) in human urine using gas chromatography-mass spectrometry. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia. 2005 Dec; 149(2):465-8. doi: 10.5507/bp.2005.081. [PMID: 16601811]
  • Marie Balíková. Nonfatal and fatal DOB (2,5-dimethoxy-4-bromoamphetamine) overdose. Forensic science international. 2005 Oct; 153(1):85-91. doi: 10.1016/j.forsciint.2005.04.022. [PMID: 15979834]
  • Tatsuyuki Kanamori, Hiroyuki Inoue, Yuko Iwata, Yoshihito Ohmae, Tohru Kishi. In vivo metabolism of 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in the rat: identification of urinary metabolites. Journal of analytical toxicology. 2002 Mar; 26(2):61-6. doi: 10.1093/jat/26.2.61. [PMID: 11916016]
  • S W Toennes, M Ohlmeier, K Schmidt, G Kauert. [Explanation of an unclear neurological syndrome by toxicologic investigation]. Deutsche medizinische Wochenschrift (1946). 2000 Jul; 125(30):900-2. doi: 10.1055/s-2000-7039. [PMID: 10962972]
  • H Nishio, S Yoshikawa, Y Morimoto, Z Chen, Y Nakata. Binding affinity of sarpogrelate to 5-HT(2A) receptor ligand recognition sites in rat renal cortical and mesangial cells in culture. General pharmacology. 1999 Jul; 33(1):51-7. doi: 10.1016/s0306-3623(98)00266-3. [PMID: 10428016]
  • M S Grotewiel, E Sanders-Bush. Regulation of serotonin2A receptors in heterologous expression systems. Journal of neurochemistry. 1994 Oct; 63(4):1255-60. doi: 10.1046/j.1471-4159.1994.63041255.x. [PMID: 7931277]
  • F G Szele, D B Pritchett. High affinity agonist binding to cloned 5-hydroxytryptamine2 receptors is not sensitive to GTP analogs. Molecular pharmacology. 1993 Jun; 43(6):915-20. doi: NULL. [PMID: 8316223]
  • M J Owens, D L Knight, J C Ritchie, C B Nemeroff. The 5-hydroxytryptamine2 agonist, (+-)-1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane stimulates the hypothalamic-pituitary-adrenal (HPA) axis. II. Biochemical and physiological evidence for the development of tolerance after chronic administration. The Journal of pharmacology and experimental therapeutics. 1991 Feb; 256(2):795-800. doi: NULL. [PMID: 1847213]
  • M J Owens, D L Knight, J C Ritchie, C B Nemeroff. The 5-hydroxytryptamine2 agonist, (+-)-1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane stimulates the hypothalamic-pituitary-adrenal (HPA) axis. I. Acute effects on HPA axis activity and corticotropin-releasing factor-containing neurons in the rat brain. The Journal of pharmacology and experimental therapeutics. 1991 Feb; 256(2):787-94. doi: NULL. [PMID: 1847212]
  • T Branchek, N Adham, M Macchi, H T Kao, P R Hartig. [3H]-DOB(4-bromo-2,5-dimethoxyphenylisopropylamine) and [3H] ketanserin label two affinity states of the cloned human 5-hydroxytryptamine2 receptor. Molecular pharmacology. 1990 Nov; 38(5):604-9. doi: . [PMID: 2233697]
  • L N Domelsmith, T A Eaton, K N Houk, G M Anderson, R A Glennon, A T Shulgin, N Castagnoli, P A Kollman. Photoelectron spectra of psychotropic drugs. 6. Relationships between the physical properties and pharmacological actions of amphetamine analogues. Journal of medicinal chemistry. 1981 Dec; 24(12):1414-21. doi: 10.1021/jm00144a009. [PMID: 7310818]