s-ethylisothiourea (BioDeep_00000274704)
代谢物信息卡片
s-ethylisothiourea
化学式: C3H8N2S (104.0408168)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCSC(=N)N
InChI: InChI=1S/C3H8N2S/c1-2-6-3(4)5/h2H2,1H3,(H3,4,5)
描述信息
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents
D004791 - Enzyme Inhibitors
同义名列表
1 个代谢物同义名
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Lianyi Lu, Takahiro Shimizu, Kumiko Nakamura, Kunihiko Yokotani. Brain neuronal/inducible nitric oxide synthases and cyclooxygenase-1 are involved in the bombesin-induced activation of central adrenomedullary outflow in rats.
European journal of pharmacology.
2008 Aug; 590(1-3):177-84. doi:
10.1016/j.ejphar.2008.06.051. [PMID: 18598693] - Trent J Volz, James O Schenk. L-arginine increases dopamine transporter activity in rat striatum via a nitric oxide synthase-dependent mechanism.
Synapse (New York, N.Y.).
2004 Dec; 54(3):173-82. doi:
10.1002/syn.20075. [PMID: 15452864] - Thomas Wallerath, Axel Gödecke, Andrei Molojavyi, Huige Li, Jürgen Schrader, Ulrich Förstermann. Dexamethasone lacks effect on blood pressure in mice with a disrupted endothelial NO synthase gene.
Nitric oxide : biology and chemistry.
2004 Feb; 10(1):36-41. doi:
10.1016/j.niox.2004.01.008. [PMID: 15050533] - Rosa A González-Polo, Germán Soler, Andrea Rodríguezmartín, Jose M Morán, José M Fuentes. Protection against MPP+ neurotoxicity in cerebellar granule cells by antioxidants.
Cell biology international.
2004; 28(5):373-80. doi:
10.1016/j.cellbi.2004.03.005. [PMID: 15193280] - Yoshinori Murakami, Shoshiro Okada, Kunihiko Yokotani. Brain inducible nitric oxide synthase is involved in interleukin-1beta-induced activation of the central sympathetic outflow in rats.
European journal of pharmacology.
2002 Nov; 455(1):73-8. doi:
10.1016/s0014-2999(02)02580-3. [PMID: 12433597] - Barbara T Alexander, Kathy Cockrell, Farrah D Cline, Joey P Granger. Inducible nitric oxide synthase inhibition attenuates renal hemodynamics during pregnancy.
Hypertension (Dallas, Tex. : 1979).
2002 Feb; 39(2 Pt 2):586-90. doi:
10.1161/hy0202.103288. [PMID: 11882613] - T Saetre, E A Höiby, T Aspelin, G Lermark, T Egeland, T Lyberg. Aminoethyl-isothiourea, a nitric oxide synthase inhibitor and oxygen radical scavenger, improves survival and counteracts hemodynamic deterioration in a porcine model of streptococcal shock.
Critical care medicine.
2000 Aug; 28(8):2697-706. doi:
10.1097/00003246-200008000-00003. [PMID: 10966238] - E Alhan, U Küçütülü, C Erçin. The effects of nitric oxide synthase inhibitors on acute necrotising pancreatitis in rats.
The European journal of surgery = Acta chirurgica.
1998 Sep; 164(9):697-702. doi:
10.1080/110241598750005598. [PMID: 9728790] - R Singh, S Pervin, N E Rogers, L J Ignarro, G Chaudhuri. Evidence for the presence of an unusual nitric oxide- and citrulline-producing enzyme in rat kidney.
Biochemical and biophysical research communications.
1997 Mar; 232(3):672-7. doi:
10.1006/bbrc.1997.6354. [PMID: 9126334] - J Zhang, T J McCarthy, W M Moore, M G Currie, M J Welch. Synthesis and evaluation of two positron-labeled nitric oxide synthase inhibitors, S-[11C]methylisothiourea and S-(2-[18F]fluoroethyl)isothiourea, as potential positron emission tomography tracers.
Journal of medicinal chemistry.
1996 Dec; 39(26):5110-8. doi:
10.1021/jm960481q. [PMID: 8978842] - T Muraki, E Fujii, M Okada, H Horikawa, K Irie, K Ohba. Effect of S-ethylisothiourea, a putative inhibitor of inducible nitric oxide synthase, on mouse skin vascular permeability.
Japanese journal of pharmacology.
1996 Mar; 70(3):269-71. doi:
10.1254/jjp.70.269. [PMID: 8935721] - W R Tracey, M Nakane, F Basha, G Carter. In vivo pharmacological evaluation of two novel type II (inducible) nitric oxide synthase inhibitors.
Canadian journal of physiology and pharmacology.
1995 May; 73(5):665-9. doi:
10.1139/y95-085. [PMID: 7585335] - V I Gikavyĭ, E A Mukhin. [Effect of fentolamin and its combination with etiron on microcirculation].
Farmakologiia i toksikologiia.
1983 Jul; 46(4):49-54. doi:
NULL. [PMID: 6413246] - G V Kovalev, A A Spasov. [Influence of hypertensive substances on the kallikrein-kinin system of the blood].
Farmakologiia i toksikologiia.
1975 Jul; 38(4):449-53. doi:
NULL. [PMID: 55368]