Guanylurea (BioDeep_00000274691)
Volatile Flavor Compounds
代谢物信息卡片
化学式: C2H6N4O (102.05415860000001)
中文名称: 1-胺甲醯胍, 胍基脲
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(=NC(=O)N)(N)N
InChI: InChI=1S/C2H6N4O/c3-1(4)6-2(5)7/h(H6,3,4,5,6,7)
描述信息
CONFIDENCE standard compound; INTERNAL_ID 2784
CONFIDENCE standard compound; INTERNAL_ID 8709
CONFIDENCE Reference Standard (Level 1)
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3253
同义名列表
3 个代谢物同义名
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lei Dong, Shuai Li, Jie Huang, Wen-Jun Li, Mukhtiar Ali. Co-occurrence, toxicity, and biotransformation pathways of metformin and its intermediate product guanylurea: Current state and future prospects for enhanced biodegradation strategy.
The Science of the total environment.
2024 Apr; 921(?):171108. doi:
10.1016/j.scitotenv.2024.171108. [PMID: 38395159] - Gustavo Axel Elizalde-Velázquez, Leobardo Manuel Gómez-Oliván, Hariz Islas-Flores, María Dolores Hernández-Navarro, Sandra García-Medina, Marcela Galar-Martínez. Oxidative stress as a potential mechanism by which guanylurea disrupts the embryogenesis of Danio rerio.
The Science of the total environment.
2021 Dec; 799(?):149432. doi:
10.1016/j.scitotenv.2021.149432. [PMID: 34365262] - Lambros J Tassoulas, Ashley Robinson, Betsy Martinez-Vaz, Kelly G Aukema, Lawrence P Wackett. Filling in the Gaps in Metformin Biodegradation: a New Enzyme and a Metabolic Pathway for Guanylurea.
Applied and environmental microbiology.
2021 05; 87(11):. doi:
10.1128/aem.03003-20. [PMID: 33741630] - Elaine Ballinger, John Mosior, Travis Hartman, Kristin Burns-Huang, Ben Gold, Roxanne Morris, Laurent Goullieux, Isabelle Blanc, Julien Vaubourgeix, Sophie Lagrange, Laurent Fraisse, Stéphanie Sans, Cedric Couturier, Eric Bacqué, Kyu Rhee, Sarah M Scarry, Jeffrey Aubé, Guangbin Yang, Ouathek Ouerfelli, Dirk Schnappinger, Thomas R Ioerger, Curtis A Engelhart, Jennifer A McConnell, Kathrine McAulay, Allison Fay, Christine Roubert, James Sacchettini, Carl Nathan. Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition.
Science (New York, N.Y.).
2019 02; 363(6426):. doi:
10.1126/science.aau8959. [PMID: 30705156] - Trine Eggen, Cathrine Lillo. Antidiabetic II drug metformin in plants: uptake and translocation to edible parts of cereals, oily seeds, beans, tomato, squash, carrots, and potatoes.
Journal of agricultural and food chemistry.
2012 Jul; 60(28):6929-35. doi:
10.1021/jf301267c. [PMID: 22712757] - Christoph Trautwein, Klaus Kümmerer. Incomplete aerobic degradation of the antidiabetic drug Metformin and identification of the bacterial dead-end transformation product Guanylurea.
Chemosphere.
2011 Oct; 85(5):765-73. doi:
10.1016/j.chemosphere.2011.06.057. [PMID: 21752423] - L Giuliani, G Carmignani, E Belgrano, P Puppo. Transcatheter arterial embolization in urological tumors: the use of isobutyl-2-cyanoacrylate.
The Journal of urology.
1979 May; 121(5):630-4. doi:
10.1016/s0022-5347(17)56913-x. [PMID: 439260] - A W Mondorf. [Evidence of urinary tubular proteins in inflammatory and toxic kidney damage].
Wiener medizinische Wochenschrift. Supplement.
1975; 27(?):20-3. doi:
NULL. [PMID: 5816]