TRIMELLITIC ANHYDRIDE (BioDeep_00000272963)
代谢物信息卡片
化学式: C9H4O5 (192.0059)
中文名称: 1,2,4-苯三酸酐
谱图信息:
最多检出来源 Anoectochilus roxburghii(viridiplantae) 100%
分子结构信息
SMILES: C1=CC2=C(C=C1C(=O)O)C(=O)OC2=O
InChI: InChI=1S/C9H4O5/c10-7(11)4-1-2-5-6(3-4)9(13)14-8(5)12/h1-3H,(H,10,11)
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:53050
- PubChem: 11089
- ChEMBL: CHEMBL2137687
- CAS: 552-30-7
- PMhub: MS000004622
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Chun Hua Piao, Yan Jing Fan, Thi Van Nguyen, Chang Ho Song, Hwan-Jeong Jeong, Ok Hee Chai. Effects of thermal therapy combined with blue light-emitting diode irradiation on trimellitic anhydride-induced acute contact hypersensitivity mouse model.
The Journal of dermatological treatment.
2022 May; 33(3):1343-1350. doi:
10.1080/09546634.2020.1809622
. [PMID: 32783679] - Huawei Zhao, Jia Zhou, Haimei Lu, Anran Xi, Mengxian Luo, Keer Wang, Hongjie Lv, Huijuan Wang, Ping Wang, Jing Miao, Zhenghao Xu. Azithromycin pretreatment exacerbates atopic dermatitis in trimellitic anhydride-induced model mice accompanied by correlated changes in the gut microbiota and serum cytokines.
International immunopharmacology.
2022 Jan; 102(?):108388. doi:
10.1016/j.intimp.2021.108388
. [PMID: 34819259] - Zhiyang Lv, Xin Shan, Qingbo Tu, Jie Wang, Jing Chen, Yuwei Yang. Ginkgolide B treatment regulated intestinal flora to improve high-fat diet induced atherosclerosis in ApoE-/- mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2021 Feb; 134(?):111100. doi:
10.1016/j.biopha.2020.111100
. [PMID: 33341056] - Dae Woon Choi, Sun Young Jung, So-Young Lee, Dong-Hwa Shon, Hee Soon Shin. Rosae multiflorae Fructus Extract Improves Trimellitic Anhydride-Induced Atopic Dermatitis-Like Symptoms.
Journal of medicinal food.
2020 Dec; 23(12):1287-1295. doi:
10.1089/jmf.2020.4767
. [PMID: 33185498] - Bongjun Sur, Seungmin Kang, Mijin Kim, Seikwan Oh. Alleviation of Atopic Dermatitis Lesions by a Benzylideneacetophenone Derivative via the MAPK Signaling Pathway.
Inflammation.
2019 Jun; 42(3):1093-1102. doi:
10.1007/s10753-019-00971-w
. [PMID: 30729380] - Chun Hua Piao, Minjoo Kim, Thi Tho Bui, Eunjin Hyeon, Yanjing Fan, Chang Ho Song, Hwan-Jeong Jeong, Ok Hee Chai. Anti-Inflammatory Effects of Cold Thermal Therapy on Allergic Skin Inflammation Induced by Trimellitic Anhydride in BALB/c Mice.
Mediators of inflammation.
2019; 2019(?):1936769. doi:
10.1155/2019/1936769
. [PMID: 30833826] - Dae Woon Choi, Da-Ae Kwon, Sung Keun Jung, Hye-Jeong See, Sun Young Jung, Dong-Hwa Shon, Hee Soon Shin. Silkworm dropping extract ameliorate trimellitic anhydride-induced allergic contact dermatitis by regulating Th1/Th2 immune response.
Bioscience, biotechnology, and biochemistry.
2018 Sep; 82(9):1531-1538. doi:
10.1080/09168451.2018.1475210
. [PMID: 29806566] - Mayumi Tsuji, Yasuhiro Ishihara, Toyohi Isse, Chihaya Koriyama, Megumi Yamamoto, Noriaki Kakiuchi, Hsu-Sheng Yu, Masayuki Tanaka, Takuto Tsuchiya, Masanori Ohta, Rie Tanaka, Toshihiro Kawamoto. Evaluation of chemical-specific IgG antibodies in male workers from a urethane foam factory.
Environmental health and preventive medicine.
2018 Jun; 23(1):24. doi:
10.1186/s12199-018-0713-4
. [PMID: 29921217] - A Elkama, O C Ulker, E Teker, A Karakaya, A E Karakaya. Investigation of hypersensitivity potential of diacetyl by determining cytokine profiles.
Human & experimental toxicology.
2018 Mar; 37(3):265-274. doi:
10.1177/0960327117695636
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Journal of immunotoxicology.
2016 09; 13(5):676-85. doi:
10.3109/1547691x.2016.1154904
. [PMID: 27404449] - Sung Keun Jung, Dae Woon Choi, Da-Ae Kwon, Min Jung Kim, Ki Seung Seong, Dong-Hwa Shon. Oral Administration of Achyranthis radix Extract Prevents TMA-induced Allergic Contact Dermatitis by Regulating Th2 Cytokine and Chemokine Production in Vivo.
Molecules (Basel, Switzerland).
2015 Dec; 20(12):21584-96. doi:
10.3390/molecules201219788
. [PMID: 26633349] - M Yeom, B J Sur, J Park, S G Cho, B Lee, S T Kim, K S Kim, H Lee, D H Hahm. Oral administration of Lactobacillus casei variety rhamnosus partially alleviates TMA-induced atopic dermatitis in mice through improving intestinal microbiota.
Journal of applied microbiology.
2015 Aug; 119(2):560-70. doi:
10.1111/jam.12844
. [PMID: 25968453] - Min-Jung Bae, Hee Soon Shin, Dae-Woon Choi, Dong-Hwa Shon. Antiallergic effect of Trigonella foenum-graecum L. extracts on allergic skin inflammation induced by trimellitic anhydride in BALB/c mice.
Journal of ethnopharmacology.
2012 Dec; 144(3):514-22. doi:
10.1016/j.jep.2012.09.030
. [PMID: 23036811] - Zhi-Hua Cui, Madeleine Rådinger, Margareta Sjöstrand, Jan Lötvall. Repeated allergen exposure reduce early phase airway response and leukotriene release despite upregulation of 5-lipoxygenase pathways.
Clinical and translational allergy.
2012 Mar; 2(?):7. doi:
10.1186/2045-7022-2-7
. [PMID: 22439792] - C Frieke Kuper, Marijana Radonjic, Jos van Triel, Rob Stierum, Rianne J de Groot, Josje H E Arts. Oxazolone (OXA) is a respiratory allergen in Brown Norway rats.
Toxicology.
2011 Nov; 290(1):59-68. doi:
10.1016/j.tox.2011.08.017
. [PMID: 21893156] - Jonathan A Bernstein, Debajyoti Ghosh, Wesley J Sublett, Heather Wells, Linda Levin. Is trimellitic anhydride skin testing a sufficient screening tool for selectively identifying TMA-exposed workers with TMA-specific serum IgE antibodies?.
Journal of occupational and environmental medicine.
2011 Oct; 53(10):1122-7. doi:
10.1097/jom.0b013e31822cfd16
. [PMID: 21915071] - Liesu Meng, Xiaojing He, Wenhua Zhu, Xudong Yang, Congshan Jiang, Qingzhu Sun, M B, Simeng Zhang, Qian Xue, Xinfang Xie, Shemin Lu. TLR3 and TLR7 modulate IgE production in antigen induced pulmonary inflammation via influencing IL-4 expression in immune organs.
PloS one.
2011 Feb; 6(2):e17252. doi:
10.1371/journal.pone.0017252
. [PMID: 21364926] - Vanessa De Vooght, Jeroen A J Vanoirbeek, Katrien Luyts, Steven Haenen, Benoit Nemery, Peter H M Hoet. Choice of mouse strain influences the outcome in a mouse model of chemical-induced asthma.
PloS one.
2010 Sep; 5(9):e12581. doi:
10.1371/journal.pone.0012581
. [PMID: 20830207] - Tomoki Fukuyama, Yukari Tajima, Hideo Ueda, Koichi Hayashi, Yasufumi Shutoh, Takanori Harada, Tadashi Kosaka. A method for measuring mouse respiratory allergic reaction to low-dose chemical exposure to allergens: an environmental chemical of uncertain allergenicity, a typical contact allergen and a non-sensitizing irritant.
Toxicology letters.
2010 May; 195(1):35-43. doi:
10.1016/j.toxlet.2010.02.016
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Bioresource technology.
2010 Apr; 101(7):2520-4. doi:
10.1016/j.biortech.2009.11.028
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Toxicology letters.
2008 Oct; 181(3):163-70. doi:
10.1016/j.toxlet.2008.07.017
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Toxicology letters.
2008 Jul; 180(1):1-8. doi:
10.1016/j.toxlet.2008.05.001
. [PMID: 18571882] - Xing-Dong Zhang, Michael E Andrew, Ann F Hubbs, Paul D Siegel. Airway responses in Brown Norway rats following inhalation sensitization and challenge with trimellitic anhydride.
Toxicological sciences : an official journal of the Society of Toxicology.
2006 Dec; 94(2):322-9. doi:
10.1093/toxsci/kfl107
. [PMID: 16982671] - Dingena L Valstar, Marcel A Schijf, Josje H E Arts, C Frieke Kuper, Frans P Nijkamp, Gert Storm, Nanne Bloksma, Paul A J Henricks. Alveolar macrophages suppress non-specific inflammation caused by inhalation challenge with trimellitic anhydride conjugated to albumin.
Archives of toxicology.
2006 Sep; 80(9):561-71. doi:
10.1007/s00204-006-0081-5
. [PMID: 16485118] - Dingena L Valstar, Marcel A Schijf, Erietta Stelekati, Frans P Nijkamp, Nanne Bloksma, Paul A J Henricks. Trimellitic anhydride-conjugated serum albumin activates rat alveolar macrophages in vitro.
Journal of occupational medicine and toxicology (London, England).
2006 Jun; 1(?):13. doi:
10.1186/1745-6673-1-13
. [PMID: 16796737] - Jeroen A J Vanoirbeek, Maciej Tarkowski, Hadewijch M Vanhooren, Vanessa De Vooght, Benoit Nemery, Peter H M Hoet. Validation of a mouse model of chemical-induced asthma using trimellitic anhydride, a respiratory sensitizer, and dinitrochlorobenzene, a dermal sensitizer.
The Journal of allergy and clinical immunology.
2006 May; 117(5):1090-7. doi:
10.1016/j.jaci.2006.01.027
. [PMID: 16675337] - Dingena L Valstar, Marcel A Schijf, Frans P Nijkamp, Gert Storm, Josje H E Arts, C Frieke Kuper, Nanne Bloksma, Paul A J Henricks. Alveolar macrophages have a dual role in a rat model for trimellitic anhydride-induced occupational asthma.
Toxicology and applied pharmacology.
2006 Feb; 211(1):20-9. doi:
10.1016/j.taap.2005.05.012
. [PMID: 15992840] - Amy L Greene, Mark S Rutherford, Ronald R Regal, Gail H Flickinger, Julie A Hendrickson, Cecilia Giulivi, Margaret E Mohrman, Daniel G Fraser, Jean F Regal. Arginase activity differs with allergen in the effector phase of ovalbumin- versus trimellitic anhydride-induced asthma.
Toxicological sciences : an official journal of the Society of Toxicology.
2005 Dec; 88(2):420-33. doi:
10.1093/toxsci/kfi311
. [PMID: 16141432] - Tai L Guo, W Auttachoat, Rui P Chi. Genistein enhancement of respiratory allergen trimellitic anhydride-induced IgE production by adult B6C3F1 mice following in utero and postnatal exposure.
Toxicological sciences : an official journal of the Society of Toxicology.
2005 Oct; 87(2):399-408. doi:
10.1093/toxsci/kfi268
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Journal of immunology (Baltimore, Md. : 1950).
2005 Jul; 175(1):43-50. doi:
10.4049/jimmunol.175.1.43
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Toxicology and applied pharmacology.
2005 Jun; 205(3):259-70. doi:
10.1016/j.taap.2004.10.011
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Journal of applied toxicology : JAT.
2005 May; 25(3):239-47. doi:
10.1002/jat.1062
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Chemical research in toxicology.
2005 Feb; 18(2):375-81. doi:
10.1021/tx049688+
. [PMID: 15720145] - John H Butala, Raymond M David, Gerhard Gans, Richard H McKee, Tai L Guo, Vanessa L Peachee, Kimber L White. Phthalate treatment does not influence levels of IgE or Th2 cytokines in B6C3F1 mice.
Toxicology.
2004 Sep; 201(1-3):77-85. doi:
10.1016/j.tox.2004.04.004
. [PMID: 15297022] - Aimen K Farraj, Jack R Harkema, Norbert E Kaminski. Allergic rhinitis induced by intranasal sensitization and challenge with trimellitic anhydride but not with dinitrochlorobenzene or oxazolone in A/J mice.
Toxicological sciences : an official journal of the Society of Toxicology.
2004 Jun; 79(2):315-25. doi:
10.1093/toxsci/kfh112
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Inhalation toxicology.
2004 May; 16(5):259-69. doi:
10.1080/08958370490427932
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Toxicology.
2003 Dec; 194(1-2):147-61. doi:
10.1016/s0300-483x(03)00338-x
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Journal of applied toxicology : JAT.
2003 Jul; 23(4):199-207. doi:
10.1002/jat.907
. [PMID: 12884401] - Josje H E Arts, Nanne Bloksma, Thea Leusink-Muis, C Frieke Kuper. Respiratory allergy and pulmonary irritation to trimellitic anhydride in Brown Norway rats.
Toxicology and applied pharmacology.
2003 Feb; 187(1):38-49. doi:
10.1016/s0041-008x(02)00023-6
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Journal of immunology (Baltimore, Md. : 1950).
2002 Dec; 169(12):7063-70. doi:
10.4049/jimmunol.169.12.7063
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Journal of applied toxicology : JAT.
2002 Nov; 22(6):397-403. doi:
10.1002/jat.876
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Toxicology.
2002 Sep; 178(2):89-99. doi:
10.1016/s0300-483x(02)00190-7
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Toxicology.
2002 Apr; 172(3):157-68. doi:
10.1016/s0300-483x(01)00566-2
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International archives of allergy and immunology.
2002 Jan; 127(1):63-72. doi:
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Journal of applied toxicology : JAT.
2002 Jan; 22(1):1-11. doi:
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Journal of agricultural and food chemistry.
2001 Oct; 49(10):4950-5. doi:
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Toxicology and applied pharmacology.
2001 Sep; 175(3):234-42. doi:
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The Journal of pharmacology and experimental therapeutics.
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Toxicology letters.
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Allergy.
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Toxicology.
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Chest.
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The European respiratory journal.
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Occupational and environmental medicine.
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Toxicology and applied pharmacology.
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The European respiratory journal.
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Toxicology.
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Cellular immunology.
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Allergy.
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