LUOTONIN A (BioDeep_00000272702)

   


代谢物信息卡片


LUOTONIN A

化学式: C18H11N3O (285.0902)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C2=CC3=CC=CC=C3N=C2C4=NC5=CC=CC=C5C(=O)N41
InChI: InChI=1S/C18H11N3O/c22-18-13-6-2-4-8-15(13)20-17-16-12(10-21(17)18)9-11-5-1-3-7-14(11)19-16/h1-9H,10H2

描述信息

同义名列表

1 个代谢物同义名

LUOTONIN A



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Ren-Xuan Wang, Sha-Sha Du, Jing-Ru Wang, Qing-Ru Chu, Chen Tang, Zhi-Jun Zhang, Cheng-Jie Yang, Ying-Hui He, Hai-Xing Li, Tian-Lin Wu, Ying-Qian Liu. Design, Synthesis, and Antifungal Evaluation of Luotonin A Derivatives against Phytopathogenic Fungi. Journal of agricultural and food chemistry. 2021 Dec; 69(48):14467-14477. doi: 10.1021/acs.jafc.1c04242. [PMID: 34843231]
  • Yanan Hao, Kaihua Wang, Ziwen Wang, Yuxiu Liu, Dejun Ma, Qingmin Wang. Luotonin A and Its Derivatives as Novel Antiviral and Antiphytopathogenic Fungus Agents. Journal of agricultural and food chemistry. 2020 Aug; 68(33):8764-8773. doi: 10.1021/acs.jafc.0c04278. [PMID: 32806124]
  • Guan-Zhou Yang, Jian Zhang, Jing-Wen Peng, Zhi-Jun Zhang, Wen-Bin Zhao, Ren-Xuan Wang, Kun-Yuan Ma, Jun-Cai Li, Ying-Qian Liu, Zhong-Min Zhao, Xiao-Fei Shang. Discovery of luotonin A analogues as potent fungicides and insecticides: Design, synthesis and biological evaluation inspired by natural alkaloid. European journal of medicinal chemistry. 2020 May; 194(?):112253. doi: 10.1016/j.ejmech.2020.112253. [PMID: 32222678]
  • Mookkandi Palsamy Kesavan, Niranjan G Kotla, Srinivasan Ayyanaar, Gujuluva Gangatharan Vinoth Kumar, Gurusamy Rajagopal, Gandhi Sivaraman, Thomas J Webster, Jegathalaprathaban Rajesh. A theranostic nanocomposite system based on iron oxide-drug nanocages for targeted magnetic field responsive chemotherapy. Nanomedicine : nanotechnology, biology, and medicine. 2018 07; 14(5):1643-1654. doi: 10.1016/j.nano.2018.04.013. [PMID: 29689372]
  • Mookkandi Palsamy Kesavan, Gujuluva Gangatharan Vinoth Kumar, Kandasamy Anitha, Lokesh Ravi, Jeyaraj Dhaveethu Raja, Gurusamy Rajagopal, Jegathalaprathaban Rajesh. Natural alkaloid Luotonin A and its affixed acceptor molecules: Serum albumin binding studies. Journal of photochemistry and photobiology. B, Biology. 2017 Aug; 173(?):499-507. doi: 10.1016/j.jphotobiol.2017.06.030. [PMID: 28668519]
  • Víctor González-Ruiz, Pierluigi Mussardo, Elisa Corda, Stefano Girotti, Ana I Olives, María Antonia Martín. Liquid chromatographic analysis of the anticancer alkaloid luotonin A and some new derivatives in human serum samples. Journal of separation science. 2010 Jul; 33(14):2086-93. doi: 10.1002/jssc.201000175. [PMID: 20568252]
  • Ali Cagir, Shannon H Jones, Rong Gao, Brian M Eisenhauer, Sidney M Hecht. Luotonin A. A naturally occurring human DNA topoisomerase I poison. Journal of the American Chemical Society. 2003 Nov; 125(45):13628-9. doi: 10.1021/ja0368857. [PMID: 14599178]