Adenosyl-Ornithine;A-9145;Antibiotic 32232RP (BioDeep_00000272647)
代谢物信息卡片
化学式: C15H23N7O5 (381.1760588)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CC(CCC(C(=O)O)N)N)O)O)N
InChI: InChI=1S/C15H23N7O5/c16-6(1-2-7(17)15(25)26)3-8-10(23)11(24)14(27-8)22-5-21-9-12(18)19-4-20-13(9)22/h4-8,10-11,14,23-24H,1-3,16-17H2,(H,25,26)(H2,18,19,20)
描述信息
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Soon Goo Lee, Youngchang Kim, Tara D Alpert, Akina Nagata, Joseph M Jez. Structure and reaction mechanism of phosphoethanolamine methyltransferase from the malaria parasite Plasmodium falciparum: an antiparasitic drug target.
The Journal of biological chemistry.
2012 Jan; 287(2):1426-34. doi:
10.1074/jbc.m111.315267. [PMID: 22117061] - Soon Goo Lee, William Haakenson, James P McCarter, D Jeremy Williams, Michelle C Hresko, Joseph M Jez. Thermodynamic evaluation of ligand binding in the plant-like phosphoethanolamine methyltransferases of the parasitic nematode Haemonchus contortus.
The Journal of biological chemistry.
2011 Nov; 286(44):38060-38068. doi:
10.1074/jbc.m111.290619. [PMID: 21914812] - Julien Vaubourgeix, Fabienne Bardou, Fanny Boissier, Sylviane Julien, Patricia Constant, Olivier Ploux, Mamadou Daffé, Annaïk Quémard, Lionel Mourey. S-adenosyl-N-decyl-aminoethyl, a potent bisubstrate inhibitor of mycobacterium tuberculosis mycolic acid methyltransferases.
The Journal of biological chemistry.
2009 Jul; 284(29):19321-30. doi:
10.1074/jbc.m809599200. [PMID: 19439410] - Lynnette M A Dirk, E Megan Flynn, Kevin Dietzel, Jean-François Couture, Raymond C Trievel, Robert L Houtz. Kinetic manifestation of processivity during multiple methylations catalyzed by SET domain protein methyltransferases.
Biochemistry.
2007 Mar; 46(12):3905-15. doi:
10.1021/bi6023644. [PMID: 17338551] - Ya-Fei Chen, Andrew Y Zhang, Ai-Ping Zou, William B Campbell, Pin-Lan Li. Protein methylation activates reconstituted ryanodine receptor-ca release channels from coronary artery myocytes.
Journal of vascular research.
2004 May; 41(3):229-40. doi:
10.1159/000078178. [PMID: 15118362] - B Goldberg, D Rattendi, N Yarlett, D Lloyd, C J Bacchi. Effects of carboxylmethylation and polyamine synthesis inhibitors on methylation of Trypanosoma brucei cellular proteins and lipids.
The Journal of eukaryotic microbiology.
1997 Jul; 44(4):352-8. doi:
10.1111/j.1550-7408.1997.tb05677.x. [PMID: 9225449]