sulfaguanidine (BioDeep_00000272312)

   


代谢物信息卡片


sulfaguanidine

化学式: C7H10N4O2S (214.0524)
中文名称: 磺胺胍
谱图信息: 最多检出来源 Viridiplantae(plant) 100%

分子结构信息

SMILES: C1=CC(=CC=C1N)S(=O)(=O)N=C(N)N
InChI: InChI=1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11)

描述信息

A - Alimentary tract and metabolism > A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents > A07A - Intestinal antiinfectives > A07AB - Sulfonamides
C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent
D000890 - Anti-Infective Agents > D013424 - Sulfanilamides
CONFIDENCE standard compound; INTERNAL_ID 1012

同义名列表

1 个代谢物同义名

sulfaguanidine



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Anna Białk-Bielińska, Joanna Maszkowska, Wojciech Mrozik, Agata Bielawska, Marta Kołodziejska, Richard Palavinskas, Piotr Stepnowski, Jolanta Kumirska. Sulfadimethoxine and sulfaguanidine: their sorption potential on natural soils. Chemosphere. 2012 Mar; 86(10):1059-65. doi: 10.1016/j.chemosphere.2011.11.058. [PMID: 22197018]
  • Yanhua Cui, Hailing Zhang, Ying ma, Cuihong Dai, Jie Cui. [Synthesis and identification of artificial antigens for sulfaguanidine and sulfathiazole]. Wei sheng yan jiu = Journal of hygiene research. 2010 Jul; 39(4):440-3. doi: . [PMID: 20726233]
  • N Mora Diez, A Muñoz de la Peña, M C Mahedero García, D Bohoyo Gil, F Cañada-Cañada. Fluorimetric determination of sulphaguanidine and sulphamethoxazole by host-guest complexation in beta-cyclodextrin and partial least squares calibration. Journal of fluorescence. 2007 May; 17(3):309-18. doi: 10.1007/s10895-007-0174-4. [PMID: 17393284]
  • M K Minev, S Iordanov, D Ganovski, V Khvŭrchilkov, I Veselinova. [Epizootiology, prevention and control of salmonellosis in swine]. Veterinarno-meditsinski nauki. 1987; 24(6):52-60. doi: NULL. [PMID: 3672906]
  • N Mizuno, M Nishikata, E Morita, K Miyake. Gastrointestinal absorption of sulfaguanidine in neonatal and adult rats. Journal of pharmacobio-dynamics. 1986 Oct; 9(10):787-92. doi: 10.1248/bpb1978.9.787. [PMID: 3820055]
  • K Sakai, N Oshima, T Kutsuna, Y Miyazaki, H Nakajima, T Muraoka, K Okuma, T Nishino. [Pharmaceutical studies on crude drugs. I. Effect of the Zingiberaceae crude drug extracts on sulfaguanidine absorption from rat small intestine]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 1986 Oct; 106(10):947-50. doi: ". [PMID: 3820090]
  • W A Koontz, R Shiman. Beef kidney 3-hydroxyanthranilic acid oxygenase. Purification, characterization, and analysis of the assay. The Journal of biological chemistry. 1976 Jan; 251(2):368-77. doi: . [PMID: 1387]
  • M Kh Canovska. [Dynamics of agglutination in birds artificially infected with Salmonella gallinarum-pullorum and Salmonella typhimurium and treated with sulfaguanidine and furazolidone]. Veterinarno-meditsinski nauki. 1976; 13(7):16-24. doi: NULL. [PMID: 797104]
  • V Schirrmacher, H Wigzell. Immune responses against native and chemically modified albumins in mice. II. Effect of electric charge and conformation on the humoral antibody response and on helper T cell responses. Journal of immunology (Baltimore, Md. : 1950). 1974 Nov; 113(5):1635-43. doi: NULL. [PMID: 4138630]
  • D B Zilversmit, L B Hughes. Validation of a dual-isotope plasma ratio method for measurement of cholesterol absorption in rats. Journal of lipid research. 1974 Sep; 15(5):465-73. doi: 10.1016/s0022-2275(20)36766-3. [PMID: 4472423]
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  • P Nielsen. The metabolism of four sulphonamides in cows. The Biochemical journal. 1973 Dec; 136(4):1039-45. doi: 10.1042/bj1361039. [PMID: 4786525]
  • H Eyssen, H Vanderhaeghe, P De Somer. Effect of polybasic antibiotics and sulfaguanidine on absorption and excretion of cholesterol and bile salts. Federation proceedings. 1971 Nov; 30(6):1803-7. doi: NULL. [PMID: 5124964]
  • J F Van den Bosch, G A Janssen, H Eyssen, H Vanderhaeghe. Specific inhibition of cholesterol absorption in sulfaguanidine-fed rats. The Journal of nutrition. 1971 Nov; 101(11):1515-23. doi: 10.1093/jn/101.11.1515. [PMID: 5124039]
  • H J Eyssen, J F Van den Bosch, G A Janssen, H Vanderhaeghe. Specific inhibition of cholesterol absorption by sulfaguanidine. Atherosclerosis. 1971 Sep; 14(2):181-92. doi: 10.1016/0021-9150(71)90048-7. [PMID: 5118612]
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  • B Tóth, B Kelentey, K Czinder, T Vályi-Nagy. [Distribution of sulfonamide-N4-glycosides in single organs of rabbit]. Arzneimittel-Forschung. 1969 Sep; 19(9):1524-7. doi: NULL. [PMID: 5394527]
  • M V Rao, N Chandrasekhara, M Srinivasan. The influence of sulfaguanidine on the biogenesis of ascorbic acid in the rat. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 1968 Jun; 128(2):402-7. doi: 10.3181/00379727-128-33023. [PMID: 5663245]
  • G A Leveille, K Chakrabarty. Total lipid and cholesterol levels in plasma and liver of rats fed diets supplemented with sulfaguanidine or succinylsulfathiazole. The Journal of nutrition. 1968 May; 95(1):88-94. doi: 10.1093/jn/95.1.88. [PMID: 5653279]
  • T Yamada, A E Lewis. An essential role of thyroxine and triiodothyronine balance in establishing normal pituitary-thyroid feedback control in goitrogen-treated rats. Endocrinology. 1968 Jan; 82(1):91-9. doi: 10.1210/endo-82-1-91. [PMID: 4169407]
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  • H Kurz, G Friemel. [Species specific difference in binding to plasma proteins]. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie. 1967; 257(1):35-6. doi: NULL. [PMID: 4231849]
  • P Reizenstein. Errors and artefacts in serum folic-acid assays. Effects of age, food, drugs and radiation. Acta medica Scandinavica. 1965 Aug; 178(2):133-9. doi: 10.1111/j.0954-6820.1965.tb04257.x. [PMID: 5834914]
  • B TOTH, B KELENTEY, K CZINDER. [IN VIVO HYDROLYSIS OF SULFONAMIDE-N4-GLYCOSIDES AND THEIR LINKAGE TO PROTEINS]. Kiserletes orvostudomany. 1964 Apr; 16(?):126-31. doi: NULL. [PMID: 14155556]
  • J W INGALLS. The potential value of sulfaguanidine in urology. Science (New York, N.Y.). 1954 Feb; 119(3084):191-2. doi: 10.1126/science.119.3084.191. [PMID: 13122059]
  • L TENTORI, G VIVALDI. [Lethal syndrome characterized by neurological symptoms of rats fed a highly purified diet containing sulfaguanidine. III. Preventive effect of feces and of fractions of feces of rats on normal diet]. Rendiconti - Istituto superiore di sanita. 1954; 17(1):19-32. doi: NULL. [PMID: 13167514]
  • N TANEW. [Comments on the treatise of Professor Bibus: 'On the misuse of intravenous urography']. Der Praktische Arzt. 1951 Jun; 5(49):1062-8. doi: NULL. [PMID: 14853769]
  • G ROULIN. A very severe typhoid fever that is dramatically improved during treatment with sulfaguanidine plasma. L'echo medical du nord. 1948 Jul; 19(7):194. doi: NULL. [PMID: 18933537]
  • P B WOOLLEY. A case of sulphaguanidine anuria. British medical journal. 1947 Apr; 1(4503):567. doi: 10.1136/bmj.1.4503.567. [PMID: 20248057]
  • J A ZIEGLER. The effect of riboflavin deficiency on renal damage due to sulphanilyl guanidine in the albino rat. Canadian journal of research. 1946 Feb; 24(Sect E):25-30. doi: NULL. [PMID: 21018959]