JWH-015 (BioDeep_00000272164)
代谢物信息卡片
化学式: C23H21NO (327.1623056)
中文名称: (2-甲基-1-丙基-1H-吲哚-3-基)-1-萘基甲酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCN1C(=C(C2=CC=CC=C21)C(=O)C3=CC=CC4=CC=CC=C43)C
InChI: InChI=1S/C23H21NO/c1-3-15-24-16(2)22(20-12-6-7-14-21(20)24)23(25)19-13-8-10-17-9-4-5-11-18(17)19/h4-14H,3,15H2,1-2H3
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D063385 - Cannabinoid Receptor Modulators
D018377 - Neurotransmitter Agents > D063385 - Cannabinoid Receptor Modulators > D063386 - Cannabinoid Receptor Agonists
同义名列表
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:92318
- PubChem: 4273754
- Metlin: METLIN45156
- ChEMBL: CHEMBL306764
- CAS: 155471-08-2
- PMhub: MS000003453
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Shaness A Grenald, Madison A Young, Yue Wang, Michael H Ossipov, Mohab M Ibrahim, Tally M Largent-Milnes, Todd W Vanderah. Synergistic attenuation of chronic pain using mu opioid and cannabinoid receptor 2 agonists.
Neuropharmacology.
2017 04; 116(?):59-70. doi:
10.1016/j.neuropharm.2016.12.008. [PMID: 28007501] - Leah Y Liu, Kristen Alexa, Mauricio Cortes, Stephanie Schatzman-Bone, Andrew J Kim, Bani Mukhopadhyay, Resat Cinar, George Kunos, Trista E North, Wolfram Goessling. Cannabinoid receptor signaling regulates liver development and metabolism.
Development (Cambridge, England).
2016 Feb; 143(4):609-22. doi:
10.1242/dev.121731. [PMID: 26884397] - A N A Verty, A Stefanidis, A J McAinch, D H Hryciw, Brian Oldfield. Anti-Obesity Effect of the CB2 Receptor Agonist JWH-015 in Diet-Induced Obese Mice.
PloS one.
2015; 10(11):e0140592. doi:
10.1371/journal.pone.0140592. [PMID: 26588700] - Sabina Strano-Rossi, Luca Anzillotti, Stefania Dragoni, Roberto Maria Pellegrino, Laura Goracci, Vincenzo Lorenzo Pascali, Gabriele Cruciani. Metabolism of JWH-015, JWH-098, JWH-251, and JWH-307 in silico and in vitro: a pilot study for the detection of unknown synthetic cannabinoids metabolites.
Analytical and bioanalytical chemistry.
2014 Jun; 406(15):3621-36. doi:
10.1007/s00216-014-7793-9. [PMID: 24804821] - Anders Helander, Olof Beck, Robert Hägerkvist, Peter Hultén. Identification of novel psychoactive drug use in Sweden based on laboratory analysis--initial experiences from the STRIDA project.
Scandinavian journal of clinical and laboratory investigation.
2013 Aug; 73(5):400-6. doi:
10.3109/00365513.2013.793817. [PMID: 23692208] - Rachel Ribeiro, Jie Wen, Shihe Li, Yumin Zhang. Involvement of ERK1/2, cPLA2 and NF-κB in microglia suppression by cannabinoid receptor agonists and antagonists.
Prostaglandins & other lipid mediators.
2013 Jan; 100-101(?):1-14. doi:
10.1016/j.prostaglandins.2012.11.003. [PMID: 23219970] - Benjamin S Harvey, Katharina S Ohlsson, Jesper L V Mååg, Ian F Musgrave, Scott D Smid. Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro.
Neurotoxicology.
2012 Jan; 33(1):138-46. doi:
10.1016/j.neuro.2011.12.015. [PMID: 22233683] - G Griffin, Q Tao, M E Abood. Cloning and pharmacological characterization of the rat CB(2) cannabinoid receptor.
The Journal of pharmacology and experimental therapeutics.
2000 Mar; 292(3):886-94. doi:
. [PMID: 10688601]