Clopidol (BioDeep_00000272125)
代谢物信息卡片
化学式: C7H7Cl2NO (190.99046719999998)
中文名称: 氯羟吡啶
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C(=O)C(=C(N1)C)Cl)Cl
InChI: InChI=1S/C7H7Cl2NO/c1-3-5(8)7(11)6(9)4(2)10-3/h1-2H3,(H,10,11)
描述信息
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C277 - Antiprotozoal Agent
CONFIDENCE standard compound; INTERNAL_ID 1183
CONFIDENCE standard compound; INTERNAL_ID 1083
同义名列表
1 个代谢物同义名
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:183853
- KEGGdrug: D03559
- PubChem: 18087
- Metlin: METLIN43547
- ChEMBL: CHEMBL446918
- MeSH: Clopidol
- CAS: 2971-90-6
- MoNA: AU118301
- MoNA: AU108305
- MoNA: AU108304
- MoNA: AU108303
- MoNA: AU108302
- PMhub: MS000003404
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - R Izaguirre-Avila, A De la Peña-Díaz, F Barinagarrementería-Aldatz, H González-Pacheco, A E Ramírez-Gutierrez, J L Ruiz-Sandoval, A Quiroz-Martínez, C Cantú-Brito. Effect of clopidogrel on platelet aggregation and plasma concentration of fibrinogen in subjects with cerebral or coronary atherosclerotic disease.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.
2002 Apr; 8(2):169-77. doi:
10.1177/107602960200800214. [PMID: 12121059] - G F Pang, Y Z Cao, C L Fan, J J Zhang, X M Li. Determination of clopidol residues in chicken tissues by liquid chromatography: part I. Optimization of analytical conditions and comparison with AOAC gas chromatography method.
Journal of AOAC International.
2001 Sep; 84(5):1337-42. doi:
NULL. [PMID: 11601450] - G F Pang, Y Z Cao, C L Fan, J J Zhang, X M Li, C Wang. Determination of clopidol residues in chicken tissues by high-performance liquid chromatography-mass spectrometry.
Journal of chromatography. A.
2000 Jun; 882(1-2):85-8. doi:
10.1016/s0021-9673(00)00436-2. [PMID: 10895935] - A Daugschies, U Gässlein, M Rommel. Comparative efficacy of anticoccidials under the conditions of commercial broiler production and in battery trials.
Veterinary parasitology.
1998 Apr; 76(3):163-71. doi:
10.1016/s0304-4017(97)00203-3. [PMID: 9615950] - A Arakawa, Y Tanaka, E Baba, T Fukata. Effects of clopidol on sporulation and infectivity of Eimeria tenella oocysts.
Veterinary parasitology.
1991 Jan; 38(1):55-60. doi:
10.1016/0304-4017(91)90008-j. [PMID: 2024430] - L P Joyner, J Catchpole, S Berrett. Eimeria stiedai in rabbits: the demonstration of responses to chemotherapy.
Research in veterinary science.
1983 Jan; 34(1):64-7. doi:
10.1016/s0034-5288(18)32285-9. [PMID: 6132429] - E Suzuki, M Matsuda, A Momose, M Namekata. Improved method for gas-liquid chromatographic determination of clopidol in chicken tissues.
Journal - Association of Official Analytical Chemists.
1980 Nov; 63(6):1211-4. doi:
NULL. [PMID: 7451382] - L R McDougald, R B Galloway. Eimeria tenella: inhibition of development in cell culture by serum from chickens fed anticoccidial drugs.
Zeitschrift fur Parasitenkunde (Berlin, Germany).
1977 Dec; 54(1):95-100. doi:
10.1007/bf00380642. [PMID: 602371] - O V Popov, R R Smiller. [State of glucocorticoid activity in patients with different histologic variants of Hodgkin's disease].
Problemy gematologii i perelivaniia krovi.
1977 Jan; 22(1):11-5. doi:
NULL. [PMID: 834733] - J R Coats, R L Metcalf, P Y Lu, D D Brown, J F Williams, L G Hansen. Model ecosystem evaluation of the environmental impacts of the veterinary drugs phenothiazine, sulfamethazine, clopidol, and diethylstilbestrol.
Environmental health perspectives.
1976 Dec; 18(?):167-79. doi:
10.1289/ehp.7618167. [PMID: 1037611] - O Oe, A Arakawa. Effect of feed additive antibiotics on chickens infected with Eimeria tenella.
Poultry science.
1975 Jul; 54(4):1008-18. doi:
10.3382/ps.0541008. [PMID: 1161694] - M Mitrovic, E G Schildknecht. Lasalocid: resistance and cross-resistance studies in Eimeria tenella-infected chicks.
Poultry science.
1975 May; 54(3):750-6. doi:
10.3382/ps.0540750. [PMID: 1153374] - B D Cameron, L F Chasseaud, D R Hawkins. Metabolic fate of clopidol after repeated oral administration to rabbits.
Journal of agricultural and food chemistry.
1975 Mar; 23(2):269-74. doi:
10.1021/jf60198a052. [PMID: 1133301]