TYLVALOSIN (BioDeep_00000272123)
代谢物信息卡片
化学式: C53H87NO19 (1041.5871992)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)OC(=O)C)C)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)OC(=O)CC(C)C)(C)O)N(C)C)O)CC=O)C)C)COC4C(C(C(C(O4)C)O)OC)OC
InChI: InChI=1S/C53H87NO19/c1-16-38-36(26-65-52-49(64-15)48(63-14)44(60)31(7)67-52)22-28(4)17-18-37(57)29(5)23-35(19-20-55)46(30(6)39(69-34(10)56)24-41(59)70-38)73-51-45(61)43(54(12)13)47(32(8)68-51)72-42-25-53(11,62)50(33(9)66-42)71-40(58)21-27(2)3/h17-18,20,22,27,29-33,35-36,38-39,42-52,60-62H,16,19,21,23-26H2,1-15H3/b18-17+,28-22+/t29-,30+,31-,32-,33+,35+,36-,38-,39-,42+,43-,44-,45-,46-,47-,48-,49-,50+,51+,52-,53-/m1/s1
数据库引用编号
7 个数据库交叉引用编号
- KEGGdrug: D10032
- PubChem: 6441094
- PubChem: 76418621
- DrugBank: DB11554
- ChEMBL: CHEMBL2103834
- CAS: 63409-12-1
- PMhub: MS000003398
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lili Zhang, Zhiyao Li, Xiaohong Deng, Jiansheng Li, Taomei Li, Yingjun Lv. Tylvalosin administration in pregnant sows attenuates the enlargement and bluish coloration of inguinal lymph nodes in newborn piglets.
Research in veterinary science.
2019 Aug; 125(?):148-152. doi:
10.1016/j.rvsc.2019.06.006. [PMID: 31228738] - P Canning, J Bates, K Skoland, J Coetzee, L Wulf, S Rajewski, C Wang, P Gauger, A Ramirez, L Karriker. Variation in water disappearance, daily dose, and synovial fluid concentrations of tylvalosin and 3-O-acetyltylosin in commerical pigs during five day water medication with tylvalosin under field conditions.
Journal of veterinary pharmacology and therapeutics.
2018 Aug; 41(4):632-636. doi:
10.1111/jvp.12503. [PMID: 29572923] - Nan Zhang, Xiaomei Ye, Yuzhi Wu, Zilong Huang, Xiaoyan Gu, Qinren Cai, Xiangguang Shen, Hongxia Jiang, Huanzhong Ding. Determination of the Mutant Selection Window and Evaluation of the Killing of Mycoplasma gallisepticum by Danofloxacin, Doxycycline, Tilmicosin, Tylvalosin and Valnemulin.
PloS one.
2017; 12(1):e0169134. doi:
10.1371/journal.pone.0169134. [PMID: 28052123] - Fatma I Abo El-Ela, S A S Shany, Manal B El-Deen, H A El-Banna, A A El-Gendy, K Hendy, M A Tohamy. Investigating the potential role of vitamin E in modulating the immunosuppressive effects of tylvalosin and florfenicol in broiler chickens.
Research in veterinary science.
2016 Oct; 108(?):25-32. doi:
10.1016/j.rvsc.2016.07.008. [PMID: 27663366] - Zhanzhong Zhao, Xiangfang Tang, Xinghui Zhao, Minhong Zhang, Weijian Zhang, Shaohua Hou, Weifeng Yuan, Hongfu Zhang, Lijun Shi, Hong Jia, Lin Liang, Zhi Lai, Junfeng Gao, Keyu Zhang, Ling Fu, Wei Chen. Tylvalosin exhibits anti-inflammatory property and attenuates acute lung injury in different models possibly through suppression of NF-κB activation.
Biochemical pharmacology.
2014 Jul; 90(1):73-87. doi:
10.1016/j.bcp.2014.04.015. [PMID: 24792436] - C Garcés-Narro, J I Barragán, M D Soler, M Mateos, M C López-Mendoza, J Homedes. Efficacy of low-dose tylvalosin for the control of clostridiosis in broilers and its effect on productive parameters.
Poultry science.
2013 Apr; 92(4):975-8. doi:
10.3382/ps.2012-02750. [PMID: 23472021] - Märit Pringle, Annica Landén, Helle Ericsson Unnerstad, Benedicta Molander, Björn Bengtsson. Antimicrobial susceptibility of porcine Brachyspira hyodysenteriae and Brachyspira pilosicoli isolated in Sweden between 1990 and 2010.
Acta veterinaria Scandinavica.
2012 Sep; 54(?):54. doi:
10.1186/1751-0147-54-54. [PMID: 22998753] - T M Jacks, F R Judith, S D Feighner, R O Likoff. 3-Acetyl-4''-isovaleryl tylosin for prevention of swine dysentery.
American journal of veterinary research.
1986 Nov; 47(11):2325-8. doi:
. [PMID: 3789492]