Benproperine (BioDeep_00000271466)
代谢物信息卡片
化学式: C21H27NO (309.20925320000003)
中文名称: 苯丙哌林
谱图信息:
最多检出来源 Viridiplantae(plant) 85.71%
分子结构信息
SMILES: CC(COC1=CC=CC=C1CC2=CC=CC=C2)N3CCCCC3
InChI: InChI=1S/C21H27NO/c1-18(22-14-8-3-9-15-22)17-23-21-13-7-6-12-20(21)16-19-10-4-2-5-11-19/h2,4-7,10-13,18H,3,8-9,14-17H2,1H3
描述信息
R - Respiratory system > R05 - Cough and cold preparations > R05D - Cough suppressants, excl. combinations with expectorants
C78273 - Agent Affecting Respiratory System > C66917 - Antitussive Agent
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3296
同义名列表
1 个代谢物同义名
数据库引用编号
15 个数据库交叉引用编号
- ChEBI: CHEBI:94380
- KEGGdrug: D07512
- PubChem: 2326
- DrugBank: DB13309
- ChEMBL: CHEMBL2105910
- CAS: 2156-27-6
- MoNA: FiehnHILIC001785
- MoNA: FiehnHILIC000212
- MoNA: EQ329606
- MoNA: EQ329605
- MoNA: EQ329604
- MoNA: EQ329603
- MoNA: EQ329602
- MoNA: EQ329601
- PMhub: MS000002514
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Di Wu, Dayu Liu, Yin Zhang, Zhen Zhang, Hui Li. Unravelling the binding mechanism of benproperine with human serum albumin: A docking, fluorometric, and thermodynamic approach.
European journal of medicinal chemistry.
2018 Feb; 146(?):245-250. doi:
10.1016/j.ejmech.2018.01.064. [PMID: 29407954] - Suling Feng, Jingjing Liu, Xiangming Han, Jing Fan. Resonance light scattering study on the interaction of benproperine phosphate with eriochrome blue black R in the presence of sodium dodecylbenzene sulphonate and its analytical application.
Luminescence : the journal of biological and chemical luminescence.
2009 Mar; 24(2):67-72. doi:
10.1002/bio.1064. [PMID: 18800357] - Yan Li, Yuming Sun, Yu Dong, Yifan Zhang, Dafang Zhong. Identification and quantitative determination of benproperine metabolites in human plasma and urine by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2006 Jan; 830(1):71-80. doi:
10.1016/j.jchromb.2005.10.011. [PMID: 16280263] - Yan Li, Da-Fang Zhong, Si-Wei Chen, Isamu Maeba. Identification of some benproperine metabolites in humans and investigation of their antitussive effect.
Acta pharmacologica Sinica.
2005 Dec; 26(12):1519-26. doi:
10.1111/j.1745-7254.2005.00212.x. [PMID: 16297353] - Z M Du, D F Zhong, Y Kang, X Y Chen. [Enantioselective pharmacokinetics of benproperine in healthy volunteers].
Yao xue xue bao = Acta pharmaceutica Sinica.
2000 Dec; 35(12):909-12. doi:
NULL. [PMID: 12567913] - Z M Du, H H Huang, X Y Chen, D F Zhong. [Study on hydroxylated metabolites of benproperine in human urine].
Yao xue xue bao = Acta pharmaceutica Sinica.
2000 Dec; 35(12):916-20. doi:
NULL. [PMID: 12567915]