METHIOCARB (BioDeep_00000271388)
Main id: BioDeep_00000014877
代谢物信息卡片
METHIOCARB
化学式: C11H15NO2S (225.0823)
中文名称: 甲醇中甲硫威溶液
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC(=CC(=C1SC)C)OC(=O)NC
InChI: InChI=1S/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)
描述信息
C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor
D010575 - Pesticides > D008975 - Molluscacides
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals
CONFIDENCE standard compound; EAWAG_UCHEM_ID 2937
同义名列表
2 个代谢物同义名
数据库引用编号
24 个数据库交叉引用编号
- ChEBI: CHEBI:38508
- KEGG: C18651
- PubChem: 16248
- ChEMBL: CHEMBL1076495
- MeSH: Methiocarb
- CAS: 2032-65-7
- MoNA: EA293714
- MoNA: EA293713
- MoNA: EA293712
- MoNA: EA293711
- MoNA: EA293710
- MoNA: EA293709
- MoNA: EA293708
- MoNA: EA293707
- MoNA: EA293706
- MoNA: EA293705
- MoNA: EA293704
- MoNA: EA293703
- MoNA: EA293702
- MoNA: EA293701
- PMhub: MS000002273
- PubChem: 124489325
- RefMet: Methiocarb
- KNApSAcK: 38508
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Sandra Halwachs, Ingo Schäfer, Carsten Kneuer, Peter Seibel, Walther Honscha. Assessment of ABCG2-mediated transport of pesticides across the rabbit placenta barrier using a novel MDCKII in vitro model.
Toxicology and applied pharmacology.
2016 08; 305(?):66-74. doi:
10.1016/j.taap.2016.06.007. [PMID: 27288731] - Chieri Fujino, Yuki Tamura, Satoko Tange, Hiroyuki Nakajima, Seigo Sanoh, Yoko Watanabe, Naoto Uramaru, Hiroyuki Kojima, Kouichi Yoshinari, Shigeru Ohta, Shigeyuki Kitamura. Metabolism of methiocarb and carbaryl by rat and human livers and plasma, and effect on their PXR, CAR and PPARα activities.
The Journal of toxicological sciences.
2016; 41(5):677-91. doi:
10.2131/jts.41.677. [PMID: 27665777] - Satoko Tange, Nariaki Fujimoto, Naoto Uramaru, Fung Fuh Wong, Kazumi Sugihara, Shigeru Ohta, Shigeyuki Kitamura. In vitro metabolism of methiocarb and carbaryl in rats, and its effect on their estrogenic and antiandrogenic activities.
Environmental toxicology and pharmacology.
2016 Jan; 41(?):289-97. doi:
10.1016/j.etap.2015.08.014. [PMID: 26774076] - Sibel Ozden, Betul Catalgol, Selda Gezginci-Oktayoglu, Ayse Karatug, Sehnaz Bolkent, Buket Alpertunga. Acute effects of methiocarb on oxidative damage and the protective effects of vitamin E and taurine in the liver and kidney of Wistar rats.
Toxicology and industrial health.
2013 Feb; 29(1):60-71. doi:
10.1177/0748233712446719. [PMID: 22623520] - A M Kammon, R S Brar, S Sodhi, H S Banga, H S Sandhu. Neuropathological studies of chickens following exposure to chlorpyrifos.
Toxicology international.
2010 Jul; 17(2):78-81. doi:
10.4103/0971-6580.72675. [PMID: 21170250] - Sibel Ozden, Buket Alpertunga. Effects of methiocarb on lipid peroxidation and glutathione level in rat tissues.
Drug and chemical toxicology.
2010; 33(1):50-4. doi:
10.3109/01480540903130708. [PMID: 19827908] - Sibel Ozden, Betul Catalgol, Selda Gezginci-Oktayoglu, Pelin Arda-Pirincci, Sehnaz Bolkent, Buket Alpertunga. Methiocarb-induced oxidative damage following subacute exposure and the protective effects of vitamin E and taurine in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2009 Jul; 47(7):1676-84. doi:
10.1016/j.fct.2009.04.018. [PMID: 19394395] - A Thierauf, H Gnann, M Bohnert, B Vennemann, V Auwärter, W Weinmann. Suicidal poisoning with mercaptodimethur-morphological findings and toxicological analysis.
International journal of legal medicine.
2009 Jul; 123(4):327-31. doi:
10.1007/s00414-008-0313-8. [PMID: 19148665] - Jiyou Han, Mira Park, Jae-Hong Kim, Ahyoung Kim, Miae Won, Dong Ryul Lee, Jeong-Jae Ko, Ho Yoon, Se-Hoon Sim, Kangseok Lee, Jeehyeon Bae. Increased expression of the testicular estrogen receptor alpha in adult mice exposed to low doses of methiocarb.
Journal of applied toxicology : JAT.
2009 Jul; 29(5):446-51. doi:
10.1002/jat.1417. [PMID: 19206145] - Amina E Essawy, Nabila E Abdelmeguied, Mohamed A Radwan, Sherifa S Hamed, Amira E Hegazy. Neuropathological effect of carbamate molluscicides on the land snail, Eobania vermiculata.
Cell biology and toxicology.
2009 Jun; 25(3):275-90. doi:
10.1007/s10565-008-9077-7. [PMID: 18470629] - Tania Portolés, María Ibáñez, Juan V Sancho, Francisco J López, Félix Hernández. Combined use of GC-TOF MS and UHPLC-(Q)TOF MS to investigate the presence of nontarget pollutants and their metabolites in a case of honeybee poisoning.
Journal of agricultural and food chemistry.
2009 May; 57(10):4079-90. doi:
10.1021/jf900099u. [PMID: 19382786] - Rosa Ma González-Rodríguez, Raquel Rial-Otero, Beatriz Cancho-Grande, Jesús Simal-Gándara. Determination of 23 pesticide residues in leafy vegetables using gas chromatography-ion trap mass spectrometry and analyte protectants.
Journal of chromatography. A.
2008 Jul; 1196-1197(?):100-9. doi:
10.1016/j.chroma.2008.02.087. [PMID: 18343389] - Helle R Andersen, Ida M Schmidt, Philippe Grandjean, Tina K Jensen, Esben Budtz-Jørgensen, Mia B Kjaerstad, Jesper Baelum, Jesper B Nielsen, Niels E Skakkebaek, Katharina M Main. Impaired reproductive development in sons of women occupationally exposed to pesticides during pregnancy.
Environmental health perspectives.
2008 Apr; 116(4):566-72. doi:
10.1289/ehp.10790. [PMID: 18414644] - Tanja Krüger, Philip S Hjelmborg, Bo A G Jönsson, Lars Hagmar, Aleksander Giwercman, Gian-Carlo Manicardi, Davide Bizzaro, Marcello Spanò, Anna Rignell-Hydbom, Henning S Pedersen, Gunnar Toft, Jens Peter Bonde, Eva C Bonefeld-Jørgensen. Xenoandrogenic activity in serum differs across European and Inuit populations.
Environmental health perspectives.
2007 Dec; 115 Suppl 1(?):21-7. doi:
10.1289/ehp.9353. [PMID: 18174946] - Ilhan Altinok, Erol Capkin. Histopathology of rainbow trout exposed to sublethal concentrations of methiocarb or endosulfan.
Toxicologic pathology.
2007 Apr; 35(3):405-10. doi:
10.1080/01926230701230353. [PMID: 17455089] - Eva C Bonefeld-Jorgensen, Philip S Hjelmborg, Thayaline S Reinert, Birgitte S Andersen, Vladimir Lesovoy, Christian H Lindh, Lars Hagmar, Aleksander Giwercman, Mogens Erlandsen, Gian-Carlo Manicardi, Marcello Spanò, Gunnar Toft, Jens Peter Bonde. Xenoestrogenic activity in blood of European and Inuit populations.
Environmental health : a global access science source.
2006 May; 5(?):12. doi:
10.1186/1476-069x-5-12. [PMID: 16674832] - Tyrone B Hayes, Paola Case, Sarah Chui, Duc Chung, Cathryn Haeffele, Kelly Haston, Melissa Lee, Vien Phoung Mai, Youssra Marjuoa, John Parker, Mable Tsui. Pesticide mixtures, endocrine disruption, and amphibian declines: are we underestimating the impact?.
Environmental health perspectives.
2006 Apr; 114 Suppl 1(?):40-50. doi:
10.1289/ehp.8051. [PMID: 16818245] - Anne Marie Vinggaard, Sofie Christiansen, Peter Laier, Mette Erecius Poulsen, Vibeke Breinholt, Kirsten Jarfelt, Helene Jacobsen, Majken Dalgaard, Christine Nellemann, Ulla Hass. Perinatal exposure to the fungicide prochloraz feminizes the male rat offspring.
Toxicological sciences : an official journal of the Society of Toxicology.
2005 Jun; 85(2):886-97. doi:
10.1093/toxsci/kfi150. [PMID: 15788727] - C Wilson, P Strimple, S Wilson, J Albano. Nontarget deposition of methiocarb applied to a foliage plant staging area.
Bulletin of environmental contamination and toxicology.
2005 Mar; 74(3):509-17. doi:
10.1007/s00128-005-0614-2. [PMID: 15903185] - Bjarte Furnes, Daniel Schlenk. Extrahepatic metabolism of carbamate and organophosphate thioether compounds by the flavin-containing monooxygenase and cytochrome P450 systems.
Drug metabolism and disposition: the biological fate of chemicals.
2005 Feb; 33(2):214-8. doi:
10.1124/dmd.104.000984. [PMID: 15547051] - S Dahamna, N Sekfali, C H Walker. Biochemical indicators of hepatotoxic effects of pesticides.
Communications in agricultural and applied biological sciences.
2004; 69(4):821-8. doi:
. [PMID: 15756876] - Louise C Simms, Christopher E Mullins, Michael J Wilson. Seed dressings to control slug damage in oilseed rape.
Pest management science.
2002 Jul; 58(7):687-94. doi:
10.1002/ps.514. [PMID: 12146169] - J B Nielsen, F Nielsen. Dermal in vitro penetration of methiocarb, paclobutrazol, and pirimicarb.
Occupational and environmental medicine.
2000 Nov; 57(11):734-7. doi:
10.1136/oem.57.11.734. [PMID: 11024196] - K A Tarrant, G E Westlake. Laboratory evaluation of the hazard to wood mice, Apodemus sylvaticus, from the agricultural use of methiocarb molluscicide pellets.
Bulletin of environmental contamination and toxicology.
1988 Jan; 40(1):147-52. doi:
10.1007/bf01689401. [PMID: 3345361] - E Blee, F Durst. Hydroperoxide-dependent sulfoxidation catalyzed by soybean microsomes.
Archives of biochemistry and biophysics.
1987 Apr; 254(1):43-52. doi:
10.1016/0003-9861(87)90079-8. [PMID: 3579305] - K J Strankowski, C W Stanley. Determination of residues of mesurol and its sulfoxide and sulfone in plant, animal, and soil samples.
Journal of agricultural and food chemistry.
1981 Sep; 29(5):1034-7. doi:
10.1021/jf00107a036. [PMID: 7309987] - M O'Keeffe, C Pierse. Exposure of seed pelleting plant workers to methiocarb.
Bulletin of environmental contamination and toxicology.
1980 Nov; 25(5):777-81. doi:
10.1007/bf01985607. [PMID: 7470653]
