Zilpaterol (BioDeep_00000271097)

   


代谢物信息卡片


Zilpaterol

化学式: C14H19N3O2 (261.14771939999997)
中文名称: 齐帕特罗
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)NC1CCn2c(O)nc3cccc(c32)C1O
InChI: InChI=1S/C14H19N3O2/c1-8(2)15-11-6-7-17-12-9(13(11)18)4-3-5-10(12)16-14(17)19/h3-5,8,11,13,15,18H,6-7H2,1-2H3,(H,16,19)/t11-,13-/m1/s1

描述信息

C78273 - Agent Affecting Respiratory System > C29712 - Anti-asthmatic Agent > C319 - Bronchodilator

同义名列表

1 个代谢物同义名

Zilpaterol



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Mariana Dolores-Hernández, Elvia A Morales-Hipólito, Alma Villaseñor, Raquel López-Arellano. Determination of zilpaterol in a residue depletion study using LC-MS/MS in cattle plasma, muscle, liver and kidney. Food chemistry. 2022 Jul; 382(?):132287. doi: 10.1016/j.foodchem.2022.132287. [PMID: 35139465]
  • Benjamin C Moeller, Amel Clifford, Richard T Emery, Gwen Alarcio, Gianna Favro, Rick M Arthur. Detection and confirmation of zilpaterol in equine hair using liquid chromatography-mass spectrometry. Drug testing and analysis. 2022 Jan; 14(1):31-38. doi: 10.1002/dta.3138. [PMID: 34355536]
  • Shubhashis Chakrabarty, Weilin L Shelver, David J Smith. Electrospray Ionization Inlet Tandem Mass Spectrometry: A Hyphenated Method for the Sensitive Determination of Chemicals in Animal Tissues and Body Fluids. Journal of the American Society for Mass Spectrometry. 2021 Jan; 32(1):14-20. doi: 10.1021/jasms.9b00114. [PMID: 33401917]
  • Carolina L Gonzales, Ty E Lawrence, John P Hutcheson, Stephen B Smith. Zilpaterol hydrochloride lowers marbling score by dilution of marbling and depression of intramuscular adipocyte volume in M. longissimus dorsi of beef steers. Meat science. 2020 Dec; 170(?):108238. doi: 10.1016/j.meatsci.2020.108238. [PMID: 32682176]
  • Taylor L Barnes, Caitlin N Cadaret, Kristin A Beede, Ty B Schmidt, Jessica L Petersen, Dustin T Yates. Hypertrophic muscle growth and metabolic efficiency were impaired by chronic heat stress, improved by zilpaterol supplementation, and not affected by ractopamine supplementation in feedlot lambs1. Journal of animal science. 2019 Oct; 97(10):4101-4113. doi: 10.1093/jas/skz271. [PMID: 31410479]
  • David J Smith, Weilin L Shelver, Shubhashis Chakrabarty, Travis W Hoffman. Detection and quantification of residues in sheep exposed to trace levels of dietary zilpaterol HCl. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2019 Sep; 36(9):1289-1301. doi: 10.1080/19440049.2019.1627005. [PMID: 31219730]
  • Shubhashis Chakrabarty, Weilin L Shelver, Heldur Hakk, David J Smith. Atmospheric Solid Analysis Probe and Modified Desorption Electrospray Ionization Mass Spectrometry for Rapid Screening and Semi-Quantification of Zilpaterol in Urine and Tissues of Sheep. Journal of agricultural and food chemistry. 2018 Oct; 66(41):10871-10880. doi: 10.1021/acs.jafc.8b03925. [PMID: 30295475]
  • Weilin L Shelver, David J Smith. Development of an immunochromatographic assay for the β-adrenergic agonist feed additive zilpaterol. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2018 Aug; 35(8):1519-1529. doi: 10.1080/19440049.2018.1463568. [PMID: 29648941]
  • C L Van Bibber-Krueger, K A Miller, R G Amachawadi, H M Scott, J M Gonzalez, J S Drouillard. Interaction between supplemental zinc oxide and zilpaterol hydrochloride on growth performance, carcass traits, and blood metabolites in feedlot steers. Journal of animal science. 2017 Dec; 95(12):5573-5583. doi: 10.2527/jas2017.1761. [PMID: 29293781]
  • J O Buntyn, D Steffen, N C Burdick Sanchez, S E Sieren, S J Jones, G E Erickson, J A Carroll, T B Schmidt. Serum blood metabolite response and evaluation of select organ weight, histology, and cardiac morphology of beef heifers exposed to a dual corticotropin-releasing hormone and vasopressin challenge following supplementation of zilpaterol hydrochloride. Journal of animal science. 2017 Dec; 95(12):5327-5338. doi: 10.2527/jas2017.1913. [PMID: 29293749]
  • James E Wells, Elaine D Berry, Minseok Kim, Steven D Shackelford, Kristin E Hales. Evaluation of Commercial β-Agonists, Dietary Protein, and Shade on Fecal Shedding of Escherichia coli O157:H7 from Feedlot Cattle. Foodborne pathogens and disease. 2017 11; 14(11):649-655. doi: 10.1089/fpd.2017.2313. [PMID: 28846460]
  • D S Antonelo, M R Mazon, K E Z Nubiato, J F M Gómez, D J Brigida, R C Gomes, A S Netto, P R Leme, S L Silva. Effects of immunocastration and β-adrenergic agonists on the performance and carcass traits of feedlot finished Nellore cattle. Animal : an international journal of animal bioscience. 2017 Nov; 11(11):2103-2110. doi: 10.1017/s1751731117000842. [PMID: 28443535]
  • K E Hales, A P Foote, D W Brake, T M Brown-Brandl, V M Artegoitia, H C Freetly. Effects of zilpaterol hydrochloride on methane production, total body oxygen consumption, and blood metabolites in finishing beef steers. Journal of animal science. 2017 Jul; 95(7):3192-3197. doi: 10.2527/jas.2017.1527. [PMID: 28727087]
  • Ting-Yuan David Cheng, Weilin L Shelver, Chi-Chen Hong, Susan E McCann, Warren Davis, Yali Zhang, Christine B Ambrosone, David J Smith. Urinary Excretion of the β-Adrenergic Feed Additives Ractopamine and Zilpaterol in Breast and Lung Cancer Patients. Journal of agricultural and food chemistry. 2016 Oct; 64(40):7632-7639. doi: 10.1021/acs.jafc.6b02723. [PMID: 27641640]
  • L J Walter, N A Cole, J S Jennings, J P Hutcheson, B E Meyer, A N Schmitz, D D Reed, T E Lawrence. The effect of zilpaterol hydrochloride supplementation on energy metabolism and nitrogen and carbon retention of steers fed at maintenance and fasting intake levels. Journal of animal science. 2016 Oct; 94(10):4401-4414. doi: 10.2527/jas.2016-0612. [PMID: 27898856]
  • Daniel A Frese, Christopher D Reinhardt, Steven J Bartle, David N Rethorst, Bhupinder Bawa, Justin D Thomason, Guy H Loneragan, Daniel U Thomson. Effect of ractopamine hydrochloride and zilpaterol hydrochloride on cardiac electrophysiologic and hematologic variables in finishing steers. Journal of the American Veterinary Medical Association. 2016 Sep; 249(6):668-77. doi: 10.2460/javma.249.6.668. [PMID: 27585105]
  • J O Buntyn, N C Burdick Sanchez, T B Schmidt, G E Erickson, S E Sieren, S J Jones, J A Carroll. The metabolic, stress axis, and hematology response of zilpaterol hydrochloride supplemented beef heifers when exposed to a dual corticotropin-releasing hormone and vasopressin challenge. Journal of animal science. 2016 Jul; 94(7):2798-810. doi: 10.2527/jas.2015-0192. [PMID: 27482667]
  • K E Hales, A P Foote, S A Jones, S D Shackelford, B M Boyd, G E Erickson. The effects of zilpaterol hydrochloride and shade on blood metabolites of finishing beef steers. Journal of animal science. 2016 Jul; 94(7):2937-41. doi: 10.2527/jas.2015-9967. [PMID: 27482680]
  • N R B Cônsolo, F D Rodriguez, R S Goulart, M O Frasseto, V B Ferrari, L F P Silva. Zilpaterol hydrochloride improves feed efficiency and changes body composition in nonimplanted Nellore heifers. Journal of animal science. 2015 Oct; 93(10):4948-55. doi: 10.2527/jas.2015-9291. [PMID: 26523587]
  • C L Van Bibber-Krueger, K A Miller, G L Parsons, L K Thompson, J S Drouillard. Effects of zilpaterol hydrochloride on growth performance, blood metabolites, and fatty acid profiles of plasma and adipose tissue in finishing steers. Journal of animal science. 2015 May; 93(5):2419-27. doi: 10.2527/jas.2014-8771. [PMID: 26020337]
  • S L Parr, T R Brown, F R B Ribeiro, K Y Chung, J P Hutcheson, B R Blackwell, P N Smith, B J Johnson. Biological responses of beef steers to steroidal implants and zilpaterol hydrochloride. Journal of animal science. 2014 Aug; 92(8):3348-63. doi: 10.2527/jas.2013-7221. [PMID: 24987078]
  • T S Arp, S T Howard, D R Woerner, J A Scanga, D R McKenna, W H Kolath, P L Chapman, J D Tatum, K E Belk. Effects of dietary ractopamine hydrochloride and zilpaterol hydrochloride supplementation on performance, carcass traits, and carcass cutability in beef steers. Journal of animal science. 2014 Feb; 92(2):836-43. doi: 10.2527/jas.2013-7122. [PMID: 24664571]
  • S T Howard, D R Woerner, D J Vote, J A Scanga, R J Acheson, P L Chapman, T C Bryant, J D Tatum, K E Belk. Effects of ractopamine hydrochloride and zilpaterol hydrochloride supplementation on carcass cutability of calf-fed Holstein steers. Journal of animal science. 2014 Jan; 92(1):369-75. doi: 10.2527/jas.2013-7104. [PMID: 24243909]
  • K R Stackhouse-Lawson, M S Calvo, S E Place, T L Armitage, Y Pan, Y Zhao, F M Mitloehner. Growth promoting technologies reduce greenhouse gas, alcohol, and ammonia emissions from feedlot cattle. Journal of animal science. 2013 Nov; 91(11):5438-47. doi: 10.2527/jas.2011-4885. [PMID: 24085413]
  • K T Korn, R P Lemenager, M C Claeys, M Engstrom, J P Schoonmaker. Supplemental vitamin D3 and zilpaterol hydrochloride. I. Effect on performance, carcass traits, tenderness, and vitamin D metabolites of feedlot steers. Journal of animal science. 2013 Jul; 91(7):3322-31. doi: 10.2527/jas.2012-5960. [PMID: 23798522]
  • K T Korn, R P Lemenager, M C Claeys, J N Waddell, M Engstrom, J P Schoonmaker. Supplemental vitamin D3 and zilpaterol hydrochloride. II. Effect on calcium concentration, muscle fiber type, and calpain gene expression of feedlot steers. Journal of animal science. 2013 Jul; 91(7):3332-40. doi: 10.2527/jas.2012-5962. [PMID: 23798523]
  • M A López-Carlos, R G Ramírez, J I Aguilera-Soto, H Rodríguez, C F Aréchiga, F Méndez-Llorente, J J Chavez, C A Medina, J M Silva. Effect of the administration program of 2 β-adrenergic agonists on growth performance and carcass and meat characteristics of feedlot ram lambs. Journal of animal science. 2012 May; 90(5):1521-31. doi: 10.2527/jas.2011-3513. [PMID: 22573838]
  • E K Miller, K Y Chung, J P Hutcheson, D A Yates, S B Smith, B J Johnson. Zilpaterol hydrochloride alters abundance of β-adrenergic receptors in bovine muscle cells but has little effect on de novo fatty acid biosynthesis in bovine subcutaneous adipose tissue explants. Journal of animal science. 2012 Apr; 90(4):1317-27. doi: 10.2527/jas.2011-4589. [PMID: 22079997]
  • A Guzmán, E Gonzalez-Padilla, P Garcés-Yépez, J V Rosete-Fernandez, R C Calderón-Robles, C Murcia, C G Gutiérrez. Reduced response to an estrous induction program in postpartum beef cows treated with zilpaterol and gaining body weight. Animal reproduction science. 2012 Jan; 130(1-2):1-8. doi: 10.1016/j.anireprosci.2011.12.001. [PMID: 22277845]
  • Stine Hansen, Lorinda Frylinck, Phillip E Strydom. The effect of vitamin D(3) supplementation on texture and oxidative stability of beef loins from steers treated with zilpaterol hydrochloride. Meat science. 2012 Jan; 90(1):145-51. doi: 10.1016/j.meatsci.2011.06.014. [PMID: 21723673]
  • D W Brake, E C Titgemeyer, M L Jones. Effect of nitrogen supplementation and zilpaterol-HCl on urea kinetics in steers consuming corn-based diets. Journal of animal physiology and animal nutrition. 2011 Aug; 95(4):409-16. doi: 10.1111/j.1439-0396.2010.01064.x. [PMID: 21039927]
  • Jianrong Nie, Mingli Zhu, Jin Lian, Yunshan Pan, Xianglian Deng, Cuiping Hu. [Determination of fifteen beta-agonists in animal urine by high performance liquid chromatography-tandem mass spectrometry]. Se pu = Chinese journal of chromatography. 2010 Aug; 28(8):759-64. doi: 10.3724/sp.j.1123.2010.00759. [PMID: 21261043]
  • Weilin L Shelver, Jennifer F Thorson, Carolyn J Hammer, David J Smith. Depletion of urinary zilpaterol residues in horses as measured by ELISA and UPLC-MS/MS. Journal of agricultural and food chemistry. 2010 Apr; 58(7):4077-83. doi: 10.1021/jf904253t. [PMID: 20218607]
  • R J B Peters, J E Oosterink, A A M Stolker, C Georgakopoulos, M W F Nielen. Generic sample preparation combined with high-resolution liquid chromatography-time-of-flight mass spectrometry for unification of urine screening in doping-control laboratories. Analytical and bioanalytical chemistry. 2010 Apr; 396(7):2583-98. doi: 10.1007/s00216-010-3484-3. [PMID: 20155493]
  • Tom S Edrington, Russell L Farrow, Guy H Loneragan, Sam E Ives, Michael J Engler, John J Wagner, Marilyn J Corbin, William J Platter, David Yates, John P Hutcheson, Richard A Zinn, Todd R Callaway, Robin C Anderson, David J Nisbet. Influence of beta-agonists (ractopamine HCl and zilpaterol HCl) on fecal shedding of Escherichia coli O157:H7 in feedlot cattle. Journal of food protection. 2009 Dec; 72(12):2587-91. doi: 10.4315/0362-028x-72.12.2587. [PMID: 20003743]
  • Weilin L Shelver, David J Smith. Tissue residues and urinary excretion of zilpaterol in sheep treated for 10 days with dietary zilpaterol. Journal of agricultural and food chemistry. 2006 Jun; 54(12):4155-61. doi: 10.1021/jf060552m. [PMID: 16756341]
  • K C M Verhoeckx, R P Doornbos, J van der Greef, R F Witkamp, R J T Rodenburg. Inhibitory effects of the beta-adrenergic receptor agonist zilpaterol on the LPS-induced production of TNF-alpha in vitro and in vivo. Journal of veterinary pharmacology and therapeutics. 2005 Dec; 28(6):531-7. doi: 10.1111/j.1365-2885.2005.00691.x. [PMID: 16343285]
  • Weilin L Shelver, Hee-Joo Kim, Qing X Li. Development of a monoclonal antibody-based enzyme-linked immuosorbent assay for the beta-adrenergic agonist zilpaterol. Journal of agricultural and food chemistry. 2005 May; 53(9):3273-80. doi: 10.1021/jf0477954. [PMID: 15853359]
  • Kitty C M Verhoeckx, Sabina Bijlsma, Sonja Jespersen, Raymond Ramaker, Elwin R Verheij, Renger F Witkamp, Jan van der Greef, Richard J T Rodenburg. Characterization of anti-inflammatory compounds using transcriptomics, proteomics, and metabolomics in combination with multivariate data analysis. International immunopharmacology. 2004 Nov; 4(12):1499-514. doi: 10.1016/j.intimp.2004.07.008. [PMID: 15351319]
  • Weilin L Shelver, David J Smith. Enzyme-linked immunosorbent assay development for the beta-adrenergic agonist zilpaterol. Journal of agricultural and food chemistry. 2004 Apr; 52(8):2159-66. doi: 10.1021/jf049919i. [PMID: 15080615]