Spiramycin I (BioDeep_00000271034)
代谢物信息卡片
Spiramycin I
化学式: C43H74N2O14 (842.5139784)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1C(O)CC(=O)OC(C)CC=CC=CC(OC2CCC(N(C)C)C(C)O2)C(C)CC(CC=O)C1OC1OC(C)C(OC2CC(C)(O)C(O)C(C)O2)C(N(C)C)C1O
InChI: InChI=1S/C43H74N2O14/c1-24-21-29(19-20-46)39(59-42-37(49)36(45(9)10)38(27(4)56-42)58-35-23-43(6,51)41(50)28(5)55-35)40(52-11)31(47)22-33(48)53-25(2)15-13-12-14-16-32(24)57-34-18-17-30(44(7)8)26(3)54-34/h12-14,16,20,24-32,34-42,47,49-51H,15,17-19,21-23H2,1-11H3/b13-12+,16-14+/t24-,25-,26+,27-,28+,29+,30+,31-,32+,34+,35+,36-,37-,38-,39+,40+,41+,42+,43-/m1/s1
描述信息
A macrolide antibiotic produced by various Streptomyces species that is used to treat toxoplasmosis and various other infections of soft tissues.
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代谢反应
0 个相关的代谢反应过程信息。
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在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Aziza A M El-Shafey, Mohammed H A Hegab, Moshira M E Seliem, Ashraf M A Barakat, Nahed E Mostafa, Hanem A Abdel-Maksoud, Reda M Abdelhameed. Curcumin@metal organic frameworks nano-composite for treatment of chronic toxoplasmosis.
Journal of materials science. Materials in medicine.
2020 Oct; 31(11):90. doi:
10.1007/s10856-020-06429-y. [PMID: 33089411] - Claire Duployez, Rémi Le Guern, Claire Tinez, Anne-Laure Lejeune, Laurent Robriquet, Sophie Six, Caroline Loïez, Frédéric Wallet. Panton-Valentine Leukocidin-Secreting Staphylococcus aureus Pneumonia Complicating COVID-19.
Emerging infectious diseases.
2020 Aug; 26(8):1939-1941. doi:
10.3201/eid2608.201413. [PMID: 32298228] - Mamdouh M Hegazy, Manar S Elmehankar, Manar S Azab, Nora L El-Tantawy, Azza Abdel-Aziz. Sex dichotomy in the course of experimental latent toxoplasmosis.
Experimental parasitology.
2019 Jul; 202(?):15-21. doi:
10.1016/j.exppara.2019.05.003. [PMID: 31078550] - Xiaoli Lv, Pingping Yu. Early diagnosis and successful treatment of acquired toxoplasmosis infectious retinochoroiditis: A case report.
Medicine.
2018 Jun; 97(26):e11231. doi:
10.1097/md.0000000000011231. [PMID: 29952985] - G Lofrano, G Libralato, A Casaburi, A Siciliano, P Iannece, M Guida, L Pucci, E F Dentice, M Carotenuto. Municipal wastewater spiramycin removal by conventional treatments and heterogeneous photocatalysis.
The Science of the total environment.
2018 May; 624(?):461-469. doi:
10.1016/j.scitotenv.2017.12.145. [PMID: 29268218] - Chrisavgi Toumpeki, Dimitrios Anastasakis, Ioannis Panagoulias, Vassiliki Stamatopoulou, Tassos Georgakopoulos, Sofia Kallia-Raftopoulos, Athanasia Mouzaki, Denis Drainas. Construction of an M1GS Ribozyme for Targeted and Rapid mRNA Cleavage; Application on the Ets-2 Oncogene.
Medicinal chemistry (Shariqah (United Arab Emirates)).
2018; 14(6):604-616. doi:
10.2174/1573406414666180112115201. [PMID: 29332592] - Xiaochuan Zhang, Lili Jin, Zhe Cui, Changhao Zhang, Xue Wu, Hyun Park, Hongmei Quan, Chunmei Jin. Antiparasitic effects of oxymatrine and matrine against Toxoplasma gondii in vitro and in vivo.
Experimental parasitology.
2016 Jun; 165(?):95-102. doi:
10.1016/j.exppara.2016.03.020. [PMID: 26993085] - Mun Ock Kim, Hyung Won Ryu, Ji-Hee Choi, Tae Hyun Son, Sei-Ryang Oh, Hyun-Sun Lee, Heung Joo Yuk, Sungchan Cho, Jong Soon Kang, Chang Woo Lee, Jinhyuk Lee, Chong-Kil Lee, Sung-Tae Hong, Su Ui Lee. Anti-Obesity Effects of Spiramycin In Vitro and In Vivo.
PloS one.
2016; 11(7):e0158632. doi:
10.1371/journal.pone.0158632. [PMID: 27398599] - Yu Zhang, Zhe Tian, Miaomiao Liu, Zhou Jason Shi, Lauren Hale, Jizhong Zhou, Min Yang. High Concentrations of the Antibiotic Spiramycin in Wastewater Lead to High Abundance of Ammonia-Oxidizing Archaea in Nitrifying Populations.
Environmental science & technology.
2015 Aug; 49(15):9124-32. doi:
10.1021/acs.est.5b01293. [PMID: 26125322] - Hai-Xia Wei, Shan-Shan Wei, David S Lindsay, Hong-Juan Peng. A Systematic Review and Meta-Analysis of the Efficacy of Anti-Toxoplasma gondii Medicines in Humans.
PloS one.
2015; 10(9):e0138204. doi:
10.1371/journal.pone.0138204. [PMID: 26394212] - Dong Wang, Yuan-Yuan Zhang. [Intestinal pathological changes of Kunming mice infected by Cryptosporidium and the therapeutic efficacy of spiramycin on infected mice].
Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases.
2014 Jun; 32(3):225-8. doi:
NULL. [PMID: 25223061] - Mehdi Rashnavadi, Mohammad Nouri, Mohammad R Haji Hajikolaei, Housain Najafzadeh, Peter D Constable. Effect of spiramycin and tulathromycin on abomasal emptying rate in milk-fed calves.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire.
2014 Jan; 78(1):61-7. doi:
. [PMID: 24396182] - Hong-xia Tang, Xue-feng Xiong, Zhi-qiang Qin. [Clinical experience on treating Toxoplasma gondii infection during pregnancy by using acetyl spiramycin combined with azithromycin].
Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control.
2013 Oct; 25(5):555-6. doi:
. [PMID: 24490384] - Yonca Acikgoz, Ozan Ozkaya, Kenan Bek, Gurkan Genc, Sema Gulnar Sensoy, Murat Hokelek. Cryptosporidiosis: a rare and severe infection in a pediatric renal transplant recipient.
Pediatric transplantation.
2012 Jun; 16(4):E115-9. doi:
10.1111/j.1399-3046.2011.01473.x. [PMID: 21320246] - Wai Kit Chew, Ignacio Segarra, Stephen Ambu, Joon Wah Mak. Significant reduction of brain cysts caused by Toxoplasma gondii after treatment with spiramycin coadministered with metronidazole in a mouse model of chronic toxoplasmosis.
Antimicrobial agents and chemotherapy.
2012 Apr; 56(4):1762-8. doi:
10.1128/aac.05183-11. [PMID: 22271863] - I N Costa, M B Angeloni, L A Santana, B F Barbosa, M C P Silva, A A Rodrigues, C Rostkowsa, P M Magalhães, J D O Pena, D A O Silva, J R Mineo, E A V Ferro. Azithromycin inhibits vertical transmission of Toxoplasma gondii in Calomys callosus (Rodentia: Cricetidae).
Placenta.
2009 Oct; 30(10):884-90. doi:
10.1016/j.placenta.2009.08.002. [PMID: 19703714] - S Fesolowicz, A Kwiatkowski, M Wszola, E Podsiadly, K Ostrowski, M Durlik, L Paczek, S Tylewska-Wierzbanowska, W Rowinski, A Chmura. Chlamydia pneumoniae infection in patients after kidney transplantation treated with spiramycin.
Transplantation proceedings.
2009 Jan; 41(1):167-9. doi:
10.1016/j.transproceed.2008.09.062. [PMID: 19249505] - Kasamyra Zylan, Tom Bailey, Huw V Smith, Christudas Silvanose, Joerg Kinne, Rolf K Schuster, Kevin Hyland. An outbreak of cryptosporidiosis in a collection of Stone curlews (Burhinus oedicnemus) in Dubai.
Avian pathology : journal of the W.V.P.A.
2008 Oct; 37(5):521-6. doi:
10.1080/03079450802357019. [PMID: 18798028] - M Lefevre-Pettazzoni, A Bissery, M Wallon, G Cozon, F Peyron, M Rabilloud. Impact of spiramycin treatment and gestational age on maturation of Toxoplasma gondii immunoglobulin G avidity in pregnant women.
Clinical and vaccine immunology : CVI.
2007 Mar; 14(3):239-43. doi:
10.1128/cvi.00311-06. [PMID: 17202303] - A Franco, N Rocamora, E Merino, A Paya. [Cryptosporidiosis. A rare infection in renal transplantation].
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia.
2006; 26(6):753-4. doi:
NULL. [PMID: 17227259] - X G Shi, J P Fawcett, X Y Chen, D F Zhong. Structural identification of bitespiramycin metabolites in rat: a single oral dose study.
Xenobiotica; the fate of foreign compounds in biological systems.
2005 Apr; 35(4):343-58. doi:
10.1080/00498250500087580. [PMID: 16019956] - Xiang-guo Shi, Yu-ming Sun, Yu-feng Zhang, Da-fang Zhong. Tissue distribution of bitespiramycin and spiramycin in rats.
Acta pharmacologica Sinica.
2004 Nov; 25(11):1396-401. doi:
NULL. [PMID: 15525458] - Xin-jun Luan, Zheng-hua Song, Zhen Xiao. Monitoring sub-nanogram amount of acetylspiramycin in human urine using flow injection analysis with chemiluminescence detection.
Yao xue xue bao = Acta pharmaceutica Sinica.
2004 Jan; 39(1):64-7. doi:
NULL. [PMID: 15127585] - Dafang Zhong, Xiangguo Shi, Lu Sun, Xiaoyan Chen. Determination of three major components of bitespiramycin and their major active metabolites in rat plasma by liquid chromatography-ion trap mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2003 Jul; 791(1-2):45-53. doi:
10.1016/s1570-0232(03)00205-8. [PMID: 12798164] - Mariana Rădoi, Elena Bobescu, Ioana Agache. Rovamycine as add-on treatment in unstable angina and 4 year evolution with major cardiovascular events.
Romanian journal of internal medicine = Revue roumaine de medecine interne.
2003; 41(3):237-46. doi:
NULL. [PMID: 15526507] - Adriana Stanila, Dorina E Popa. [Treatment difficulties in ocular toxoplasmosis].
Oftalmologia (Bucharest, Romania : 1990).
2003; 56(1):40-4. doi:
NULL. [PMID: 12886681] - R Gratzl, G Sodeck, P Platzer, W Jäger, J Graf, A Pollak, T Thalhammer. Treatment of toxoplasmosis in pregnancy: concentrations of spiramycin and neospiramycin in maternal serum and amniotic fluid.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.
2002 Jan; 21(1):12-6. doi:
10.1007/s10096-001-0644-6. [PMID: 11913495] - N Furusawa. Binding profile of spiramycin to oviducal proteins of laying hens.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine.
2000 Dec; 47(10):585-91. doi:
10.1046/j.1439-0442.2000.00319.x. [PMID: 11199206] - C Schauner, A Dary, A Lebrihi, P Leblond, B Decaris, P Germain. Modulation of lipid metabolism and spiramycin biosynthesis in Streptomyces ambofaciens unstable mutants.
Applied and environmental microbiology.
1999 Jun; 65(6):2730-7. doi:
10.1128/aem.65.6.2730-2737.1999. [PMID: 10347068] - P Nielsen, N Gyrd-Hansen. Bioavailability of spiramycin and lincomycin after oral administration to fed and fasted pigs.
Journal of veterinary pharmacology and therapeutics.
1998 Aug; 21(4):251-6. doi:
10.1046/j.1365-2885.1998.00131.x. [PMID: 9731946] - I Brook. Pharmacodynamics and pharmacokinetics of spiramycin and their clinical significance.
Clinical pharmacokinetics.
1998 Apr; 34(4):303-10. doi:
10.2165/00003088-199834040-00003. [PMID: 9571302] - I Moutard, B Gressier, C Brunet, T Dine, M Luyckx, F Templier, M Cazin, J C Cazin. In vitro interaction between spiramycin and polymorphonuclear neutrophils oxidative metabolism.
Pharmacological research.
1998 Mar; 37(3):197-201. doi:
10.1006/phrs.1998.0292. [PMID: 9602467] - C C Cester, J C Béguin, P L Toutain. The use of an experimental metritis model to study antibiotic distribution in genital tract secretions in the ewe.
Veterinary research.
1996; 27(4-5):479-89. doi:
NULL. [PMID: 8822617] - T K Graczyk, M R Cranfield, S L Hill. Therapeutic efficacy of halofuginone and spiramycin treatment against Cryptosporidium serpentis (Apicomplexa: Cryptosporidiidae) infections in captive snakes.
Parasitology research.
1996; 82(2):143-8. doi:
10.1007/s004360050085. [PMID: 8825209] - M Pettoello-Mantovani, L Di Martino, G Dettori, P Vajro, S Scotti, M T Ditullio, S Guandalini. Asymptomatic carriage of intestinal Cryptosporidium in immunocompetent and immunodeficient children: a prospective study.
The Pediatric infectious disease journal.
1995 Dec; 14(12):1042-7. doi:
10.1097/00006454-199512000-00003. [PMID: 8745015] - G Abraham. Streptococcus pyogenes peritonitis associated with genital swelling and gastroenteritis caused by Cryptosporidium and Salmonella paratyphi B in an HIV infected patient on CAPD.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
1995; 10(1):140-1. doi:
NULL. [PMID: 7724018] - S L Zhou, M Tan, G Shen. Comparison of the pharmacokinetics and bioavailability of spiramycin in human serum and saliva.
The Journal of antimicrobial chemotherapy.
1994 Dec; 34(6):1080-2. doi:
10.1093/jac/34.6.1080. [PMID: 7730228] - P A Rotzetter, A Le Liboux, E Pichard, G Cimasoni. Kinetics of spiramycin/metronidazole (Rodogyl) in human gingival crevicular fluid, saliva and blood.
Journal of clinical periodontology.
1994 Oct; 21(9):595-600. doi:
10.1111/j.1600-051x.1994.tb00749.x. [PMID: 7806675] - M R Cranfield, T K Graczyk. Experimental infection of elaphid snakes with Cryptosporidium serpentis (Apicomplexa: Cryptosporidiidae).
The Journal of parasitology.
1994 Oct; 80(5):823-6. doi:
10.2307/3283265. [PMID: 7931919] - E Schoondermark-Van de Ven, J Galama, W Camps, T Vree, F Russel, J Meuwissen, W Melchers. Pharmacokinetics of spiramycin in the rhesus monkey: transplacental passage and distribution in tissue in the fetus.
Antimicrobial agents and chemotherapy.
1994 Sep; 38(9):1922-9. doi:
10.1128/aac.38.9.1922. [PMID: 7810999] - E Schoondermark-Van de Ven, W Melchers, W Camps, T Eskes, J Meuwissen, J Galama. Effectiveness of spiramycin for treatment of congenital Toxoplasma gondii infection in rhesus monkeys.
Antimicrobial agents and chemotherapy.
1994 Sep; 38(9):1930-6. doi:
10.1128/aac.38.9.1930. [PMID: 7811000] - R Mercado, M García. [Asymptomatic cryptosporidiosis in an infant].
Boletin chileno de parasitologia.
1994 Jul; 49(3-4):71-2. doi:
NULL. [PMID: 7654289] - L Renard, P Henry, P Sanders, M Laurentie, J M Delmas. Determination of spiramycin and neospiramycin in plasma and milk of lactating cows by reversed-phase high-performance liquid chromatography.
Journal of chromatography. B, Biomedical applications.
1994 Jul; 657(1):219-26. doi:
10.1016/0378-4347(94)80091-x. [PMID: 7952072] - N G Guerina, H W Hsu, H C Meissner, J H Maguire, R Lynfield, B Stechenberg, I Abroms, M S Pasternack, R Hoff, R B Eaton. Neonatal serologic screening and early treatment for congenital Toxoplasma gondii infection. The New England Regional Toxoplasma Working Group.
The New England journal of medicine.
1994 Jun; 330(26):1858-63. doi:
10.1056/nejm199406303302604. [PMID: 7818637] - Z Li, G Chen. [Evaluation of theophylline population pharmacokinetics in adult hospitalized patients using NONMEM analysis].
Zhongguo yao li xue bao = Acta pharmacologica Sinica.
1994 May; 15(3):267-70. doi:
NULL. [PMID: 7976385] - P Sanders, P Guillot, M Dagorn, G Moulin, B Delépine, D Mourot. Pharmacokinetics and tissue residues of spiramycin in cattle after intramuscular administration of multiple doses.
American journal of veterinary research.
1994 Mar; 55(3):358-62. doi:
NULL. [PMID: 8192258] - V Vacek. [Spiramycin].
Casopis lekaru ceskych.
1994 Jan; 133(2):56-60. doi:
NULL. [PMID: 8131182] - D E Corpet, R Bellier, S Petrowitsch, Y Vigouroux. Digestion and fermentation of proteins in rats fed keratin, albumin, cooked casein and antibiotics.
Reproduction, nutrition, development.
1994; 34(1):57-64. doi:
10.1051/rnd:19940106. [PMID: 7510493] - Y H Lee, D Y Lee, D W Shin. [Prophylactic effects of trimethoprim-sulfamethoxazole in Toxoplasma-infected mice].
The Korean journal of parasitology.
1993 Dec; 31(4):363-70. doi:
10.3347/kjp.1993.31.4.363. [PMID: 8297894] - G Galvagno, G Cattaneo, E Reverso-Giovantin. [Chronic diarrhea due to Cryptosporidium: the efficacy of spiramycin treatment].
La Pediatria medica e chirurgica : Medical and surgical pediatrics.
1993 May; 15(3):297-8. doi:
NULL. [PMID: 8415179] - B Wilmsmeyer, R Dopfer, J E Hoppe, D Niethammer. [Cryptosporidium enteritis].
Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde.
1993 Feb; 141(2):130-2. doi:
NULL. [PMID: 8459814] - H M Sutter, J Engeli, P Müller, B Schneider, J L Riond, M Warner. Pharmacokinetics and bioavailability of spiramycin in pigs.
The Veterinary record.
1992 Jun; 130(23):510-3. doi:
10.1136/vr.130.23.510. [PMID: 1641967] - N Brion, K Kollenbach, M H Marion, A Grégoire, C Advenier, M Pays. Effect of a macrolide (spiramycin) on the pharmacokinetics of L-dopa and carbidopa in healthy volunteers.
Clinical neuropharmacology.
1992 Jun; 15(3):229-35. doi:
10.1097/00002826-199206000-00003. [PMID: 1394243] - P Sanders, G Moulin, P Guillot, M Dagorn, P Perjant, B Delepine, C Gaudiche, D Mourot. Pharmacokinetics of spiramycin after intravenous, intramuscular and subcutaneous administration in lactating cows.
Journal of veterinary pharmacology and therapeutics.
1992 Mar; 15(1):53-61. doi:
10.1111/j.1365-2885.1992.tb00986.x. [PMID: 1573706] - J Z Zhang, X X Yang, Y H Tong. [Combined gu chi wan and spiramycin in the treatment of periodontal disease].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
1992 Feb; 12(2):83-5, 68. doi:
". [PMID: 1498532] - C C Cester, N Dubech, P L Toutain. Effect of sexual steroid hormones on spiramycin disposition in genital tract secretions of the ewe.
Journal of pharmaceutical sciences.
1992 Jan; 81(1):33-6. doi:
10.1002/jps.2600810107. [PMID: 1377747] - P Sanders, G Moulin, C Gaudiche, B Delepine, D Mourot. Comparison of automated liquid chromatographic and bioassay methods for determining spiramycin concentration in bovine plasma.
Journal - Association of Official Analytical Chemists.
1991 Nov; 74(6):912-7. doi:
NULL. [PMID: 1757414] - B Fortier, F Ajana, M I Pinto de Sousa, E Aissi, D Camus. [Prevention and treatment of materno-fetal toxoplasmosis].
Presse medicale (Paris, France : 1983).
1991 Sep; 20(29):1374-83. doi:
NULL. [PMID: 1835012] - C Friis, E Erhardsen, E B Madsen, P Nielsen, K Raun. Respiratory tract distribution and bioavailability of spiramycin in calves.
American journal of veterinary research.
1991 Aug; 52(8):1269-73. doi:
NULL. [PMID: 1928908] - F G Araujo, R M Shepard, J S Remington. In vivo activity of the macrolide antibiotics azithromycin, roxithromycin and spiramycin against Toxoplasma gondii.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.
1991 Jun; 10(6):519-24. doi:
10.1007/bf01963942. [PMID: 1655433] - B Bengtsson, A Franklin, S Jacobsson, J Luthman, M Horn af Rantzien. Distribution of penicillin-G and spiramycin to tissue cages and subcutaneous tissue fluid in calves.
Research in veterinary science.
1991 May; 50(3):301-7. doi:
10.1016/0034-5288(91)90128-b. [PMID: 1882137] - A Andremont, C Trancrède, J F Desnottes. Effect of oral spiramycin on the faecal and oral bacteria in human volunteers.
The Journal of antimicrobial chemotherapy.
1991 Mar; 27(3):355-60. doi:
10.1093/jac/27.3.355. [PMID: 1903789] - A Kondo, T Nakatani, Y Kuzuya, H Suzuki, H Sano, K Yamaguchi, K Shirahata, K Takahashi, K Kita, Y Nishiie. [Studies on acetylspiramycin. 1. Separation and chemical structures of acetylspiramycin components].
The Japanese journal of antibiotics.
1990 Jun; 43(6):1152-63. doi:
. [PMID: 2232146] - M Kessler, P Netter, H E Renoul, P Trechot, B Dousset, B Bannwarth. Lack of effect of spiramycin on cyclosporin pharmacokinetics.
British journal of clinical pharmacology.
1990 Mar; 29(3):370-1. doi:
10.1111/j.1365-2125.1990.tb03652.x. [PMID: 2360926] - C C Cester, M P Laurentie, R García-Villar, P L Toutain. Spiramycin concentrations in plasma and genital-tract secretions after intravenous administration in the ewe.
Journal of veterinary pharmacology and therapeutics.
1990 Mar; 13(1):7-14. doi:
10.1111/j.1365-2885.1990.tb00741.x. [PMID: 2319638] - E Kacprzak, M Kurczewska, J Stefaniak. [2 cases of cryptosporidiosis in adults].
Przeglad epidemiologiczny.
1990; 44(3):245-8. doi:
NULL. [PMID: 2084808] - A M Huet, F Bosc, R Floc'h, R Bayle. [The bioequivalence of two injectable solutions of spiramycin in young cattle].
Annales de recherches veterinaires. Annals of veterinary research.
1990; 21 Suppl 1(?):67S-71S. doi:
NULL. [PMID: 2080849] - J P Garin, M Mojon, M A Piens, I Chevalier-Nuttall. [Monitoring and treatment of toxoplasmosis in the pregnant woman, fetus and newborn].
Pediatrie.
1989; 44(9):705-12. doi:
NULL. [PMID: 2695891] - A Ito, K Murohashi, M Matsumura, A Honda, I Maruta, K Obara. [Experience in treatment of Mycoplasma pneumoniae with acetylspiramycin].
The Japanese journal of antibiotics.
1983 Apr; 36(4):699-708. doi:
. [PMID: 6410100] - A Inoue, T Deguchi. [The pharmacokinetic studies on spiramycin and acetylspiramycin in rats].
The Japanese journal of antibiotics.
1982 Aug; 35(8):1998-2004. doi:
. [PMID: 7154248] - F M Espinas, Y Odakura, N Suzuki, H Sasaki. [Studies on the therapeutics of experimental toxoplasmosis. I. Effect of acetylspiramycin and spiramycin on the intracardiac Toxoplasma multiplication in mice infected with Toxoplasma gondii (author's transl)].
The Japanese journal of antibiotics.
1981 Aug; 34(8):1141-7. doi:
. [PMID: 7321193]