Phenyl-N-tert-butylnitrone (BioDeep_00000270964)
代谢物信息卡片
Phenyl-N-tert-butylnitrone
化学式: C11H15NO (177.115358)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)(C)[N+]([O-])=Cc1ccccc1
InChI:
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Beatriz Chamorro, David García-Vieira, Daniel Diez-Iriepa, Estíbaliz Garagarza, Mourad Chioua, Dimitra Hadjipavlou-Litina, Francisco López-Muñoz, José Marco-Contelles, María Jesús Oset-Gasque. Synthesis, Neuroprotection, and Antioxidant Activity of 1,1'-Biphenylnitrones as α-Phenyl-N-tert-butylnitrone Analogues in In Vitro Ischemia Models.
Molecules (Basel, Switzerland).
2021 Feb; 26(4):. doi:
10.3390/molecules26041127. [PMID: 33672652] - Donny W H Merkx, Lorenz Plankensteiner, Yafei Yu, Peter A Wierenga, Marie Hennebelle, John P M Van Duynhoven. Evaluation of PBN spin-trapped radicals as early markers of lipid oxidation in mayonnaise.
Food chemistry.
2021 Jan; 334(?):127578. doi:
10.1016/j.foodchem.2020.127578. [PMID: 32721836] - Beatriz Chamorro, Daniel Diez-Iriepa, Belén Merás-Sáiz, Mourad Chioua, David García-Vieira, Isabel Iriepa, Dimitra Hadjipavlou-Litina, Francisco López-Muñoz, Ricardo Martínez-Murillo, Daniel Gonzàlez-Nieto, Israel Fernández, José Marco-Contelles, María Jesús Oset-Gasque. Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models.
Scientific reports.
2020 08; 10(1):14150. doi:
10.1038/s41598-020-70690-y. [PMID: 32843666] - Alicia Jiménez-Almarza, Daniel Diez-Iriepa, Mourad Chioua, Beatriz Chamorro, Isabel Iriepa, Ricardo Martínez-Murillo, Dimitra Hadjipavlou-Litina, María Jesús Oset-Gasque, José Marco-Contelles. Synthesis, neuroprotective and antioxidant capacity of PBN-related indanonitrones.
Bioorganic chemistry.
2019 05; 86(?):445-451. doi:
10.1016/j.bioorg.2019.01.071. [PMID: 30771691] - Larissa Socrier, Marie Rosselin, Fanny Choteau, Grégory Durand, Sandrine Morandat. Cholesterol-nitrone conjugates as protective agents against lipid oxidation: A model membrane study.
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2017 Dec; 1859(12):2495-2504. doi:
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Brain research.
2011 Sep; 1412(?):28-36. doi:
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Environmental and molecular mutagenesis.
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2010 Aug; 49(3):427-36. doi:
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Journal of applied physiology (Bethesda, Md. : 1985).
2010 Aug; 109(2):449-56. doi:
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Free radical research.
2010 Jun; 44(6):645-54. doi:
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Journal of the American College of Cardiology.
2010 Jun; 55(22):2499-508. doi:
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Toxicology and applied pharmacology.
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Die Pharmazie.
2009 Jul; 64(7):436-9. doi:
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2008 Apr; 42(4):379-86. doi:
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Toxicology letters.
2008 Feb; 176(3):169-77. doi:
10.1016/j.toxlet.2007.10.010. [PMID: 18242889] - Kui Xu, Michelle A Puchowicz, Xiaoyan Sun, Joseph C LaManna. Mitochondrial dysfunction in aging rat brain following transient global ischemia.
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Investigative ophthalmology & visual science.
2007 Apr; 48(4):1864-72. doi:
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American journal of obstetrics and gynecology.
2006 Dec; 195(6):1707-14. doi:
10.1016/j.ajog.2006.03.047. [PMID: 16769026] - Fang-Jung Wan, Che-Se Tung, I-Shin Shiah, Hui-Ching Lin. Effects of alpha-phenyl-N-tert-butyl nitrone and N-acetylcysteine on hydroxyl radical formation and dopamine depletion in the rat striatum produced by d-amphetamine.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology.
2006 Feb; 16(2):147-53. doi:
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2005 Sep; 74(4):365-71. doi:
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Analytical biochemistry.
2005 Sep; 344(2):193-203. doi:
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Environmental toxicology and chemistry.
2005 Sep; 24(9):2145-53. doi:
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Toxicology.
2005 Aug; 211(3):242-52. doi:
10.1016/j.tox.2005.03.011. [PMID: 15869837] - Young-Sook Kang, Kyeong-Eun Lee, Na-Young Lee, Tetsuya Terasaki. Donepezil, tacrine and alpha-phenyl-n-tert-butyl nitrone (PBN) inhibit choline transport by conditionally immortalized rat brain capillary endothelial cell lines (TR-BBB).
Archives of pharmacal research.
2005 Apr; 28(4):443-50. doi:
10.1007/bf02977674. [PMID: 15918518] - Joaquín Velasco, Mogens L Andersen, Leif H Skibsted. Electron spin resonance spin trapping for analysis of lipid oxidation in oils: inhibiting effect of the spin trap alpha-phenyl-N-tert-butylnitrone on lipid oxidation.
Journal of agricultural and food chemistry.
2005 Mar; 53(5):1328-36. doi:
10.1021/jf049051w. [PMID: 15740002] - H Hirano, Y Tabuchi, T Kondo, Q-L Zhao, R Ogawa, Z-G Cui, L B Feril, S Kanayama. Analysis of gene expression in apoptosis of human lymphoma U937 cells induced by heat shock and the effects of alpha-phenyl N-tert-butylnitrone (PBN) and its derivatives.
Apoptosis : an international journal on programmed cell death.
2005 Mar; 10(2):331-40. doi:
10.1007/s10495-005-0807-5. [PMID: 15843894] - Chang Won Choi, Jong Hee Hwang, Yun Sil Chang, Son Moon Shin, Won Soon Park, Munhyang Lee. Effects of alpha-phenyl-N-tert-butyl nitrone (PBN)on brain cell membrane function and energy metabolism during transient global cerebral hypoxia-ischemia and reoxygenation-reperfusion in newborn piglets.
Journal of Korean medical science.
2004 Jun; 19(3):413-8. doi:
10.3346/jkms.2004.19.3.413. [PMID: 15201509] - Christine Rauca, Ingrid Wiswedel, Renate Zerbe, Gerburg Keilhoff, Manfred Krug. The role of superoxide dismutase and alpha-tocopherol in the development of seizures and kindling induced by pentylenetetrazol - influence of the radical scavenger alpha-phenyl-N-tert-butyl nitrone.
Brain research.
2004 May; 1009(1-2):203-12. doi:
10.1016/j.brainres.2004.01.082. [PMID: 15120598] - Shuying Lin, Philip G Rhodes, Manping Lei, Feng Zhang, Zhengwei Cai. alpha-Phenyl-n-tert-butyl-nitrone attenuates hypoxic-ischemic white matter injury in the neonatal rat brain.
Brain research.
2004 May; 1007(1-2):132-41. doi:
10.1016/j.brainres.2004.01.074. [PMID: 15064144] - Mary E Lame, Amit S Kalgutkar, Michael LaFontaine. Intravenous pharmacokinetics and metabolism of the reactive oxygen scavenger alpha-phenyl-N-tert-butyl nitrone (PBN) in the cynomolgus monkey.
Drug metabolism and drug interactions.
2004; 20(1-2):11-24. doi:
10.1515/dmdi.2004.20.1-2.11. [PMID: 15283300] - Michael P Murphy, Karim S Echtay, Frances H Blaikie, Jordi Asin-Cayuela, Helena M Cocheme, Katherine Green, Julie A Buckingham, Ellen R Taylor, Fiona Hurrell, Gillian Hughes, Satomi Miwa, Christopher E Cooper, Dimitri A Svistunenko, Robin A J Smith, Martin D Brand. Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone.
The Journal of biological chemistry.
2003 Dec; 278(49):48534-45. doi:
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Bulletin of experimental biology and medicine.
2003 Dec; 136(6):560-2. doi:
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American journal of physiology. Heart and circulatory physiology.
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Free radical biology & medicine.
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General physiology and biophysics.
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