Lucidone (BioDeep_00000270469)

 

Secondary id: BioDeep_00000247240

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


4-Cyclopentene-1,3-dione, 2-(-hydroxycinnamylidene)-4-methoxy- (8CI); (2Z)-2-[(2E)-1-Hydroxy-3-phenyl-2-propenylidene]-4-methoxy-4-cyclopentene-1,3-dione

化学式: C15H12O4 (256.0736)
中文名称: 赤芝酮, LUCIDONE
谱图信息: 最多检出来源 Anoectochilus roxburghii(otcml) 50%

分子结构信息

SMILES: C1(OC)C(=O)/C(=C(/C=C/C2C=CC=CC=2)\O)/C(=O)C=1
InChI: InChI=1S/C15H12O4/c1-19-13-9-12(17)14(15(13)18)11(16)8-7-10-5-3-2-4-6-10/h2-9,18H,1H3/b8-7+

描述信息

Lucidone is an olefinic compound. It is functionally related to a cinnamic acid.
Lucidone is a natural product found in Lindera erythrocarpa with data available.

同义名列表

7 个代谢物同义名

4-Cyclopentene-1,3-dione, 2-(-hydroxycinnamylidene)-4-methoxy- (8CI); (2Z)-2-[(2E)-1-Hydroxy-3-phenyl-2-propenylidene]-4-methoxy-4-cyclopentene-1,3-dione; 4-Cyclopentene-1,3-dione, 2-[(2E)-1-hydroxy-3-phenyl-2-propenylidene]-4-methoxy-, (2Z)-; (2Z)-2-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-4-methoxycyclopent-4-ene-1,3-dione; 4-Cyclopentene-1,3-dione, 2-(1-hydroxy-3-phenyl-2-propenylidene)-4-methoxy-, (Z,E)-; 3-hydroxy-4-methoxy-2-[(E)-3-phenylprop-2-enoyl]cyclopenta-2,4-dien-1-one; Lucidone; 2- [ (1Z,2E) -1-Hydroxy-3-phenyl-2-propenylidene ] -4-methoxy-4-cyclopentene-1,3-dione



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

10 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Xitong Liu, Chen Zhang, Jianlei Huang, Haiou Liu, Bo Li, Feifei Zhang, Congjian Xu. Biomarkers identification in follicular fluid in relation to live birth in in vitro fertilization of women with polycystic ovary syndrome in different subtypes by using UPLC-MS method. Clinica chimica acta; international journal of clinical chemistry. 2024 Apr; 557(?):117860. doi: 10.1016/j.cca.2024.117860. [PMID: 38508572]
  • K J Senthil Kumar, Hsin-Ling Yang, Yu-Cheng Tsai, Pin-Chun Hung, Show-Huei Chang, Heng-Wei Lo, Pei-Chun Shen, Ssu-Ching Chen, Hui-Min Wang, Sheng-Yang Wang, Chih-Wei Chou, You-Cheng Hseu. Lucidone protects human skin keratinocytes against free radical-induced oxidative damage and inflammation through the up-regulation of HO-1/Nrf2 antioxidant genes and down-regulation of NF-κB signaling pathway. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2013 Sep; 59(?):55-66. doi: 10.1016/j.fct.2013.04.055. [PMID: 23712098]
  • Yu-Hsin Hsieh, Sheng-Yang Wang. Lucidone from Lindera erythrocarpa Makino fruits suppresses adipogenesis in 3T3-L1 cells and attenuates obesity and consequent metabolic disorders in high-fat diet C57BL/6 mice. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2013 Mar; 20(5):394-400. doi: 10.1016/j.phymed.2012.11.007. [PMID: 23265843]
  • Wei-Chun Chen, Sheng-Yang Wang, Chien-Chih Chiu, Chin-Kai Tseng, Chun-Kuang Lin, Hui-Chun Wang, Jin-Ching Lee. Lucidone suppresses hepatitis C virus replication by Nrf2-mediated heme oxygenase-1 induction. Antimicrobial agents and chemotherapy. 2013 Mar; 57(3):1180-91. doi: 10.1128/aac.02053-12. [PMID: 23254429]
  • K J Senthil Kumar, Jeng-Chuann Yang, Feng-Hua Chu, Shang-Tzen Chang, Sheng-Yang Wang. Lucidone, a novel melanin inhibitor from the fruit of Lindera erythrocarpa Makino. Phytotherapy research : PTR. 2010 Aug; 24(8):1158-65. doi: 10.1002/ptr.3018. [PMID: 20077436]
  • K J Senthil Kumar, Han Wen Hsieh, Sheng-Yang Wang. Anti-inflammatory effect of lucidone in mice via inhibition of NF-kappaB/MAP kinase pathway. International immunopharmacology. 2010 Apr; 10(4):385-92. doi: 10.1016/j.intimp.2009.12.013. [PMID: 20079881]
  • K J Senthil Kumar, Sheng-Yang Wang. Lucidone inhibits iNOS and COX-2 expression in LPS-induced RAW 264.7 murine macrophage cells via NF-kappaB and MAPKs signaling pathways. Planta medica. 2009 Apr; 75(5):494-500. doi: 10.1055/s-0029-1185309. [PMID: 19194838]
  • Sheng-Yang Wang, Xing-Yu Lan, Jun-Hong Xiao, Jeng-Chung Yang, Yi-Ting Kao, Shang-Tzen Chang. Antiinflammatory activity of Lindera erythrocarpa fruits. Phytotherapy research : PTR. 2008 Feb; 22(2):213-6. doi: 10.1002/ptr.2289. [PMID: 17726736]