Demethylvestitol (BioDeep_00000270095)

Main id: BioDeep_00000020073

PANOMIX_OTCML-2023 natural product

代谢物信息卡片

7,2,4-Trihydroxyisoflavan

化学式: C15H14O4 (258.0892044)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c1(ccc2c(c1)OC[C@H](C2)c1c(cc(cc1)O)O)O
InChI: InChI=1S/C15H14O4/c16-11-3-4-13(14(18)6-11)10-5-9-1-2-12(17)7-15(9)19-8-10/h1-4,6-7,10,16-18H,5,8H2

描述信息

D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents > D009466 - Neuromuscular Blocking Agents
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D018680 - Cholinergic Antagonists

同义名列表

2 个代谢物同义名

Demethylvestitol; 7,2,4-Trihydroxyisoflavan

数据库引用编号

9 个数据库交叉引用编号

ChEBI: CHEBI:174377
PubChem: 585939
Metlin: METLIN48272
LipidMAPS: LMPK12080027
MeSH: Pipecuronium
KNApSAcK: C00009708
CAS: 65332-45-8
Flavonoid: FLIC1LNS0004
LOTUS: LTS0215797

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

35 个相关的物种来源信息

118891 - Anthyllis vulneraria: 10.1016/S0031-9422(00)94374-7
4890 - Ascomycota: LTS0215797
210567 - Cadophora: LTS0215797
51156 - Cadophora gregata: 10.1271/BBB1961.51.349
51156 - Cadophora gregata: LTS0215797
20483 - Caragana: LTS0215797
390503 - Caragana tibetica: 10.1248/CPB.53.1204
390503 - Caragana tibetica: LTS0215797
236729 - Endosamara: LTS0215797
236730 - Endosamara racemosa: 10.1016/0031-9422(95)00735-0
236730 - Endosamara racemosa: LTS0215797
2759 - Eukaryota: LTS0215797
3803 - Fabaceae: LTS0215797
4751 - Fungi: LTS0215797
147548 - Leotiomycetes: LTS0215797
3867 - Lotus: LTS0215797
181259 - Lotus angustissimus: 10.1016/S0031-9422(00)83980-1
181259 - Lotus angustissimus: LTS0215797
181270 - Lotus edulis: 10.1016/S0031-9422(00)83980-1
181270 - Lotus edulis: LTS0215797
3398 - Magnoliopsida: LTS0215797
3883 - Phaseolus: LTS0215797
3886 - Phaseolus coccineus: 10.1016/S0031-9422(00)80697-4
3886 - Phaseolus coccineus: LTS0215797
3885 - Phaseolus vulgaris: 10.1016/0031-9422(80)85139-9
3885 - Phaseolus vulgaris: LTS0215797
2316155 - Ploettnerulaceae: LTS0215797
35493 - Streptophyta: LTS0215797
58023 - Tracheophyta: LTS0215797
3913 - Vigna: LTS0215797
3914 - Vigna angularis: 10.1271/BBB1961.51.349
3914 - Vigna angularis: LTS0215797
3915 - Vigna mungo: 10.1515/ZNC-1984-9-1006
3915 - Vigna mungo: LTS0215797
33090 - Viridiplantae: LTS0215797

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

C L Thwaites, L M Yen, S M Cordon, G E Thwaites, H T Loan, T T D Thuy, N J White, N Soni, I A Macdonald, J J Farrar. Effect of magnesium sulphate on urinary catecholamine excretion in severe tetanus. Anaesthesia. 2008 Jul; 63(7):719-25. doi: 10.1111/j.1365-2044.2008.05476.x. [PMID: 18582257]
M Thán, J Németh, Z Szilvássy, E Pintér, Z Helyes, J Szolcsányi. Systemic anti-inflammatory effect of somatostatin released from capsaicin-sensitive vagal and sciatic sensory fibres of the rat and guinea-pig. European journal of pharmacology. 2000 Jul; 399(2-3):251-8. doi: 10.1016/s0014-2999(00)00341-1. [PMID: 10884527]
K Sato, K Windisch, I Matko, E S Vizi. Effects of non-depolarizing neuromuscular blocking agents on norepinephrine release from human atrial tissue obtained during cardiac surgery. British journal of anaesthesia. 1999 Jun; 82(6):904-9. doi: 10.1093/bja/82.6.904. [PMID: 10562787]
D P Atherton, J M Hunter. Clinical pharmacokinetics of the newer neuromuscular blocking drugs. Clinical pharmacokinetics. 1999 Mar; 36(3):169-89. doi: 10.2165/00003088-199936030-00001. [PMID: 10223167]
M Brinkmann, M Günnicker, U Freund, M Schieffer, J Peters. [Histamine plasma concentration and cardiovascular effects of non-depolarizing muscle relaxants: comparison of atracurium, vecuronium, pancuronium and pipecuronium in coronary surgical patients at risk]. Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS. 1998 Jun; 33(6):362-6. doi: 10.1055/s-2007-994264. [PMID: 9689393]
W T Denman, N G Goudsouzian, C Gelb. Comparison of neuromuscular, cardiovascular, and histamine-releasing properties of doxacurium and pipecuronium. Journal of clinical anesthesia. 1996 Mar; 8(2):113-8. doi: 10.1016/0952-8180(95)00194-8. [PMID: 8695092]
P Hans, D Ledoux, V Bonhomme, J F Brichant. Effect of plasma anticonvulsant level on pipecuronium-induced neuromuscular blockade: preliminary results. Journal of neurosurgical anesthesiology. 1995 Oct; 7(4):254-8. doi: 10.1097/00008506-199510000-00003. [PMID: 8563445]
E Tassonyi, J F Pittet, C N Schopfer, J C Rouge, G Gemperle, O H Wilder-Smith, D R Morel. Pharmacokinetics of pipecuronium in infants, children and adults. European journal of drug metabolism and pharmacokinetics. 1995 Jul; 20(3):203-8. doi: 10.1007/bf03189671. [PMID: 8751042]
E Ueda, J Takeda, J Takahashi, K Fukushima. [Plasma N-methylhistamine levels following intravenous administration of pipecuronium in man]. Masui. The Japanese journal of anesthesiology. 1994 Oct; 43(10):1552-5. doi: NULL. [PMID: 7529344]
P P Neidhart, P Champion, J Vogel, E K Zsigmond, E Tassonyi. A comparison of pipecuronium with pancuronium on haemodynamic variables and plasma catecholamines in coronary artery bypass patients. Canadian journal of anaesthesia = Journal canadien d'anesthesie. 1994 Jun; 41(6):469-74. doi: 10.1007/bf03011539. [PMID: 8069985]
E M Cameron, A Lisbon, R Moorman, J D Young. Prolonged neuromuscular blockade with pipecuronium in a patient with renal insufficiency. European journal of anaesthesiology. 1994 May; 11(3):237-9. doi: . [PMID: 8050428]
D R Bevan. Newer neuromuscular blocking agents. Pharmacology & toxicology. 1994 Jan; 74(1):3-9. doi: 10.1111/j.1600-0773.1994.tb01065.x. [PMID: 8159634]
G D'Honneur, M Khalil, C Dominique, J P Haberer, U W Kleef, P Duvaldestin. Pharmacokinetics and pharmacodynamics of pipecuronium in patients with cirrhosis. Anesthesia and analgesia. 1993 Dec; 77(6):1203-6. doi: . [PMID: 8250313]
P B Embree. Long-acting nondepolarizing neuromuscular blocking agents. AANA journal. 1993 Aug; 61(4):382-7. doi: . [PMID: 8397465]
N E de Gouw, J F Crul, E Vandermeersch, J P Mulier, J van Egmond, H Van Aken. Interaction of antibiotics on pipecuronium-induced neuromuscular blockade. Journal of clinical anesthesia. 1993 May; 5(3):212-5. doi: 10.1016/0952-8180(93)90017-9. [PMID: 8391282]
R K Mirakhur. Newer neuromuscular blocking drugs. An overview of their clinical pharmacology and therapeutic use. Drugs. 1992 Aug; 44(2):182-99. doi: 10.2165/00003495-199244020-00003. [PMID: 1382013]
L Vereczkey. [Pharmacokinetics and metabolism of pipecuronium bromide (Arduan)]. Acta pharmaceutica Hungarica. 1992 May; 62(3):127-31. doi: NULL. [PMID: 1323914]
P A Caballero, R E Johnstone. Long-lasting neuromuscular blockade from pipecuronium. Anesthesiology. 1992 Jan; 76(1):154-5. doi: 10.1097/00000542-199201000-00036. [PMID: 1309627]
J M Wierda, J Szenohradszky, A P De Wit, G Zentai, S Agoston, M Kakas, U W Kleef, D K Meijer. The pharmacokinetics, urinary and biliary excretion of pipecuronium bromide. European journal of anaesthesiology. 1991 Nov; 8(6):451-7. doi: NULL. [PMID: 1662599]
M Naguib, M Abdulatif, A Absood. Comparative effects of pipecuronium and tubocurarine on plasma concentrations of histamine in humans. British journal of anaesthesia. 1991 Sep; 67(3):320-2. doi: 10.1093/bja/67.3.320. [PMID: 1654967]
J F Pittet, E Tassonyi, C Schopfer, D R Morel, P Leemann, G Mentha, C Le Coultre, D A Steinig, A Benakis. Dose requirements and plasma concentrations of pipecuronium during bilateral renal exclusion and orthotopic liver transplantation in pigs. British journal of anaesthesia. 1990 Dec; 65(6):779-85. doi: 10.1093/bja/65.6.779. [PMID: 2176089]
C Yajima, N Sugai, K Hanaoka, K Numata, K Yamamoto, Y Kushida, S Murakami, H Yamamura. [Comparative pharmacokinetics of pipecuronium bromide, pancuronium bromide and vecuronium bromide in anesthetized man]. Masui. The Japanese journal of anesthesiology. 1990 Jul; 39(7):882-9. doi: NULL. [PMID: 1976829]
J M Wierda, G F Karliczek, R H Vandenbrom, I Pinto, U W Kersten-Kleef, D K Meijer, S Agoston. Pharmacokinetics and cardiovascular dynamics of pipecuronium bromide during coronary artery surgery. Canadian journal of anaesthesia = Journal canadien d'anesthesie. 1990 Mar; 37(2):183-91. doi: 10.1007/bf03005467. [PMID: 2155718]
J Futo, J P Kupferberg, J Moss. Inhibition of histamine N-methyltransferase (HNMT) in vitro by neuromuscular relaxants. Biochemical pharmacology. 1990 Feb; 39(3):415-20. doi: 10.1016/0006-2952(90)90045-m. [PMID: 1968337]
K S Khuenl-Brady, M Sharma, K Chung, R D Miller, S Agoston, J E Caldwell. Pharmacokinetics and disposition of pipecuronium bromide in dogs with and without ligated renal pedicles. Anesthesiology. 1989 Dec; 71(6):919-22. doi: 10.1097/00000542-198912000-00015. [PMID: 2556065]
S Gábor, V László. Determination of Arduan and its desacetyl metabolites in biological fluids. Acta pharmaceutica Hungarica. 1989 Jul; 59(4):167-72. doi: NULL. [PMID: 2549761]
J E Caldwell, P C Canfell, K P Castagnoli, D P Lynam, M R Fahey, D M Fisher, R D Miller. The influence of renal failure on the pharmacokinetics and duration of action of pipecuronium bromide in patients anesthetized with halothane and nitrous oxide. Anesthesiology. 1989 Jan; 70(1):7-12. doi: 10.1097/00000542-198901000-00004. [PMID: 2536254]
J E Caldwell, K P Castagnoli, P C Canfell, M R Fahey, D P Lynam, D M Fisher, R D Miller. Pipecuronium and pancuronium: comparison of pharmacokinetics and duration of action. British journal of anaesthesia. 1988 Dec; 61(6):693-7. doi: 10.1093/bja/61.6.693. [PMID: 2849968]
S Agoston, R H Vandenbrom, J M Wierda, M C Houwertjes, U W Kersten. Pharmacokinetics and disposition of pipecuronium bromide in the cat. European journal of anaesthesiology. 1988 Jul; 5(4):233-42. doi: NULL. [PMID: 2848702]
T Furuta, P C Canfell, K P Castagnoli, M L Sharma, R D Miller. Quantitation of pancuronium, 3-desacetylpancuronium, vecuronium, 3-desacetylvecuronium, pipecuronium and 3-desacetylpipecuronium in biological fluids by capillary gas chromatography using nitrogen-sensitive detection. Journal of chromatography. 1988 May; 427(1):41-53. doi: 10.1016/0378-4347(88)80103-8. [PMID: 2900840]
E Tassonyi, G Szabó, L Vereczkey. Pharmacokinetics of pipecurium bromide, a new non-depolarizing neuromuscular blocking agent, in humans. Arzneimittel-Forschung. 1981; 31(10):1754-6. doi: NULL. [PMID: 6274362]
G Szabó, E Tassonyi. Determination of pipecurium bromide, a new non-depolarizing neuromuscular blocking agent, in human serum. Arzneimittel-Forschung. 1981; 31(6):1013-5. doi: NULL. [PMID: 6266429]
G Simon, K Biró, E Kárpáti, Z Tuba. The effect of the steroid muscle relaxant pipecurium bromide on the acetylcholinesterase activity of red blood cells in vitro. Arzneimittel-Forschung. 1980; 30(2a):360-3. doi: . [PMID: 6248079]
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O Alánt, K Darvas, I Pulay, J Weltner, I Bihari. First clinical experience with a new neuromuscular blocker pipecurium bromide. Arzneimittel-Forschung. 1980; 30(2a):374-9. doi: NULL. [PMID: 6248083]
M Boros, J Szenohradszky, G Marosi, I Tóth. Comparative clinical study of pipecurium bromide and pancuronium bromide. Arzneimittel-Forschung. 1980; 30(2a):389-93. doi: NULL. [PMID: 6248087]