17-phenyl-18,19,20-trinor-prostaglandin E2 (BioDeep_00000026903)

   

human metabolite Endogenous Volatile Flavor Compounds


代谢物信息卡片


(5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid

化学式: C23H30O5 (386.209313)
中文名称: 17-苯基-18,19,20-三去甲前列腺素 E2
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C(C(C(C1=O)CC=CCCCC(=O)O)C=CC(CCC2=CC=CC=C2)O)O
InChI: InChI=1S/C23H30O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,14-15,18-20,22,24,26H,2,7,10-13,16H2,(H,27,28)/b6-1-,15-14+/t18-,19+,20+,22+/m0/s1

描述信息

17-phenyl-18,19,20-trinor-prostaglandin E2, also known as 17-Phenyl-omega-trinor-pge2 or CL 116147, is classified as a member of the Prostaglandins and related compounds. Prostaglandins and related compounds are unsaturated carboxylic acids consisting of a 20 carbon skeleton that also contains a five member ring, and are based upon the fatty acid arachidonic acid. 17-phenyl-18,19,20-trinor-prostaglandin E2 is considered to be practically insoluble (in water) and acidic. 17-phenyl-18,19,20-trinor-prostaglandin E2 is an eicosanoid lipid molecule

同义名列表

14 个代谢物同义名

(5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid; 17-phenyl-18,19,20-trinor-prostaglandin E2; 17-Phenyl-omega-trinor-prostaglandin e2; 17-Phenyltrinor-prostaglandin e2; 17-Phenyltrinorprostaglandin e2; 17-Phenyl-18,19,20-trinor-pge2; 17-Phenyl-omega-trinor pge2; 17-Phenyl-omega-trinor-pge2; 17-phenyl-trinor-PGE2; 17-Phenyltrinor-pge2; 17-PH-Trinor-pge2; CL 116147; PD026296; 17-Phenyltrinorprostaglandin E2



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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文献列表

  • Xu Chen, Jun Yin, Yuyin Xu, Zhi Qiu, Jing Liu, Xiaolan Chen. Effect of selective inhibition or activation of PGE2 EP1 receptor on glomerulosclerosis. Molecular medicine reports. 2020 Oct; 22(4):2887-2895. doi: 10.3892/mmr.2020.11353. [PMID: 32700746]
  • Najam A Sharif, Terry L Davis. Cloned human EP1 prostanoid receptor pharmacology characterized using radioligand binding techniques. The Journal of pharmacy and pharmacology. 2002 Apr; 54(4):539-47. doi: 10.1211/0022357021778655. [PMID: 11999132]
  • J W Kim, J D Lindsey, N Wang, R N Weinreb. Increased human scleral permeability with prostaglandin exposure. Investigative ophthalmology & visual science. 2001 Jun; 42(7):1514-21. doi: NULL. [PMID: 11381055]
  • Y Boie, R Stocco, N Sawyer, D M Slipetz, M D Ungrin, F Neuschäfer-Rube, G P Püschel, K M Metters, M Abramovitz. Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes. European journal of pharmacology. 1997 Dec; 340(2-3):227-41. doi: 10.1016/s0014-2999(97)01383-6. [PMID: 9537820]