Vincadifformine (BioDeep_00000267330)

   

natural product


代谢物信息卡片


6,7-Dihydrotabersonine

化学式: C21H26N2O2 (338.1994)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c1ccc2c(c1)[C@@]13C(=C(C[C@]4([C@@H]1N(CCC4)CC3)CC)C(=O)OC)N2
InChI: InChI=1S/C21H26N2O2/c1-3-20-9-6-11-23-12-10-21(19(20)23)15-7-4-5-8-16(15)22-17(21)14(13-20)18(24)25-2/h4-5,7-8,19,22H,3,6,9-13H2,1-2H3/t19-,20-,21-/m0/s1

描述信息

Origin: Plant; SubCategory_DNP: Monoterpenoid indole alkaloids, Aspidosperma alkaloids, Indole alkaloids

同义名列表

3 个代谢物同义名

Vincadifformine; 6,7-Dihydrotabersonine; (-)-Vincadifformine



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

25 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Danielle Williams, Weronika Brzezinski, Heather Gordon, Vincenzo De Luca. Site directed mutagenesis of Catharanthus roseus (+)-vincadifformine 19-hydroxylase (CYP71BY3) results in two distinct enzymatic functions. Phytochemistry. 2022 Sep; 201(?):113265. doi: 10.1016/j.phytochem.2022.113265. [PMID: 35660549]
  • Danielle Williams, Yang Qu, Razvan Simionescu, Vincenzo De Luca. The assembly of (+)-vincadifformine- and (-)-tabersonine-derived monoterpenoid indole alkaloids in Catharanthus roseus involves separate branch pathways. The Plant journal : for cell and molecular biology. 2019 08; 99(4):626-636. doi: 10.1111/tpj.14346. [PMID: 31009114]
  • Sara Abouzeid, Ulrike Beutling, Dirk Selmar. Stress-induced modification of indole alkaloids:Phytomodificines as a new category of specialized metabolites. Phytochemistry. 2019 Mar; 159(?):102-107. doi: 10.1016/j.phytochem.2018.12.015. [PMID: 30605851]
  • Sara Abouzeid, Ulrike Beutling, Frank Surup, Fatma M Abdel Bar, Mohamed M Amer, Farid A Badria, Mahdi Yahyazadeh, Mark Brönstrup, Dirk Selmar. Treatment of Vinca minor Leaves with Methyl Jasmonate Extensively Alters the Pattern and Composition of Indole Alkaloids. Journal of natural products. 2017 11; 80(11):2905-2909. doi: 10.1021/acs.jnatprod.7b00424. [PMID: 29131648]
  • Zerihun Demessie, Kathlyn N Woolfson, Fang Yu, Yang Qu, Vincenzo De Luca. The ATP binding cassette transporter, VmTPT2/VmABCG1, is involved in export of the monoterpenoid indole alkaloid, vincamine in Vinca minor leaves. Phytochemistry. 2017 Aug; 140(?):118-124. doi: 10.1016/j.phytochem.2017.04.019. [PMID: 28478314]
  • Mei-Fen Bao, Chun-Xia Zeng, Ya-Ping Liu, Bing-Jie Zhang, Ling Ni, Xiao-Dong Luo, Xiang-Hai Cai. Indole Alkaloids from Hunteria zeylanica. Journal of natural products. 2017 04; 80(4):790-797. doi: 10.1021/acs.jnatprod.5b01035. [PMID: 28362501]
  • Kuan-Hon Lim, Osamu Hiraku, Kanki Komiyama, Takashi Koyano, Masahiko Hayashi, Toh-Seok Kam. Biologically active indole alkaloids from Kopsia arborea. Journal of natural products. 2007 Aug; 70(8):1302-7. doi: 10.1021/np0702234. [PMID: 17665953]