Mesuol (BioDeep_00000267223)

 

Secondary id: BioDeep_00000180765

PANOMIX_OTCML-2023


代谢物信息卡片


2H-1-Benzopyran-2-one, 5,7-dihydroxy-8-(3-methyl-2-butenyl)-6-(2-methyl-1-oxopropyl)-4-phenyl-

化学式: C24H24O5 (392.1623654)
中文名称:
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 73.53%

分子结构信息

SMILES: c1(c(c2c(c(cc(=O)o2)c2ccccc2)c(c1C(=O)C(C)C)O)CC=C(C)C)O
InChI: InChI=1S/C24H24O5/c1-13(2)10-11-16-22(27)20(21(26)14(3)4)23(28)19-17(12-18(25)29-24(16)19)15-8-6-5-7-9-15/h5-10,12,14,27-28H,11H2,1-4H3

描述信息

Mesuol is a neoflavonoid.
Mesuol is a natural product found in Mesua ferrea and Mammea siamensis with data available.

同义名列表

13 个代谢物同义名

2H-1-Benzopyran-2-one, 5,7-dihydroxy-8-(3-methyl-2-butenyl)-6-(2-methyl-1-oxopropyl)-4-phenyl-; 2H-1-Benzopyran-2-one,7-dihydroxy-8-(3-methyl-2-butenyl)-6-(2-methyl-1-oxopropyl)-4-phenyl-; 5,7-DIHYDROXY-8-(3-METHYL-2-BUTENYL)-6-(2-METHYLPROPANOYL)-4-PHENYL-2H-1-BENZOPYRAN-2-ONE; 5,7-dihydroxy-8-(3-methylbut-2-enyl)-6-(2-methylpropanoyl)-4-phenyl-chromen-2-one; 5,7-dihydroxy-8-(3-methylbut-2-enyl)-6-(2-methylpropanoyl)-4-phenylchromen-2-one; 5,7-dihydroxy-6-(isobutyryl)-8-(3-methylbut-2-enyl)-4-phenyl-2h-chromen-2-one; 5,7-Dihydroxy-6-isobutyryl-8-(3-methyl-but-2-enyl)-4-phenyl-chromen-2-one; 2,7-Dihydroxy-6-isobutyryl-8-(3-methyl-but-2-enyl)-4-phenyl-chromen-5-one; Coumarin,7-dihydroxy-6-isobutyryl-8-(3-methyl-2-butenyl)-4-phenyl-; 5,7-Dihydroxy-8-(3-methylbut-2-enyl)-6-isobutyryl-4-phenylcoumarin; 4-phenylcoumarin; Mesuol; 5,7-Dihydroxy-8- (3-methylbut-2-enyl) -6-isobutyryl-4-phenylcoumarin



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Lynda Bouarab, Pascal Degraeve, Jalloul Bouajila, Amandine Cottaz, Fouzia Jbilou, Catherine Joly, Nadia Oulahal. Staphylococcus aureus membrane-damaging activities of four phenolics. FEMS microbiology letters. 2021 07; 368(13):. doi: 10.1093/femsle/fnab081. [PMID: 34173656]
  • Tjitjik Srie Tjahjandarie, Mulyadi Tanjung, Dhaniar Farah Rahmania, Churin In Rhidoma, Ratih Dewi Saputri. Calodioscurins A and B, two new isoprenylated xanthones from the stem bark of Calophyllum dioscurii P.F. Stevens. Natural product research. 2021 Apr; 35(7):1153-1158. doi: 10.1080/14786419.2019.1643864. [PMID: 31328544]
  • Heiter V M Boness, Nelson A S Santos, Isis B Costa, Cintia K L Queiroz, Edson J Marques, Ramon S El-Bachá, Frederico G Cruz. Prenylated 4-phenylcoumarins and 4-alkylcoumarins from Kielmeyera argentea and their cytotoxic activity. Fitoterapia. 2021 Mar; 149(?):104836. doi: 10.1016/j.fitote.2021.104836. [PMID: 33515650]
  • Hani Sapili, Chai San Ho, Sharan Malagobadan, Norhafiza Mohd Arshad, Noor Hasima Nagoor. Geranylated 4-phenylcoumarins extracted from Mesua elegans induced caspase-independent cell death in prostate cancer cell lines through calpain-2 and cathepsin B. Scientific reports. 2020 01; 10(1):986. doi: 10.1038/s41598-020-57781-6. [PMID: 31969640]
  • Ritesh Raju, Ahilya Singh, Frances Bodkin, Gerald Münch. Costatamins A - C, new 4-phenylcoumarins with anti-inflammatory activity from the Australian woodland tree Angophora costata (Myrtaceae). Fitoterapia. 2019 Mar; 133(?):171-174. doi: 10.1016/j.fitote.2019.01.004. [PMID: 30654131]
  • Mulyadi Tanjung, Fida Rachmadiarti, Ratih Dewi Saputri, Tjitjik Srie Tjahjandarie. Mesucalophylloidin, a new isoprenylated 4-phenylcoumarin from Mesua calophylloides (Ridl.) Kosterm. Natural product research. 2018 May; 32(9):1062-1067. doi: 10.1080/14786419.2017.1378215. [PMID: 28950715]
  • Marcos Guilherme da Cunha, Gilson César Nobre Franco, Marcelo Franchin, John A Beutler, Severino Matias de Alencar, Masaharu Ikegaki, Pedro Luiz Rosalen. Prediction of pharmacokinetic and toxicological parameters of a 4-phenylcoumarin isolated from geopropolis: In silico and in vitro approaches. Toxicology letters. 2016 Nov; 263(?):6-10. doi: 10.1016/j.toxlet.2016.10.010. [PMID: 27773722]
  • Bach Tai Dang, Caroline Rouger, Marc Litaudon, Pascal Richomme, Denis Séraphin, Séverine Derbré. Identification of Minor Benzoylated 4-Phenylcoumarins from a Mammea neurophylla Bark Extract. Molecules (Basel, Switzerland). 2015 Sep; 20(10):17735-46. doi: 10.3390/molecules201017735. [PMID: 26404214]
  • Bach Tai Dang, Charlotte Gény, Patricia Blanchard, Caroline Rouger, Pierre Tonnerre, Béatrice Charreau, Gilbertine Rakolomalala, Joseph Iharinjaka Randriamboavonjy, Gervaise Loirand, Pierre Pacaud, Marc Litaudon, Pascal Richomme, Denis Séraphin, Séverine Derbré. Advanced glycation inhibition and protection against endothelial dysfunction induced by coumarins and procyanidins from Mammea neurophylla. Fitoterapia. 2014 Jul; 96(?):65-75. doi: 10.1016/j.fitote.2014.04.005. [PMID: 24731922]
  • Araceli Pérez-Vásquez, Erika Castillejos-Ramírez, Sol Cristians, Rachel Mata. Development of a UHPLC-PDA method for the simultaneous quantification of 4-phenylcoumarins and chlorogenic acid in Exostema caribaeum stem bark. Journal of natural products. 2014 Mar; 77(3):516-20. doi: 10.1021/np400785z. [PMID: 24266401]
  • S Cristians, R Mata, R Bye. Phenological and geographical influence in the concentration of selected bioactive 4-phenylcoumarins and chlorogenic acid in Hintonia latiflora leaves. Journal of ethnopharmacology. 2014 Mar; 152(2):308-13. doi: 10.1016/j.jep.2013.12.054. [PMID: 24412552]
  • Khalijah Awang, Gomathi Chan, Marc Litaudon, Nor Hadiani Ismail, Marie-Thérèse Martin, Françoise Gueritte. 4-Phenylcoumarins from Mesua elegans with acetylcholinesterase inhibitory activity. Bioorganic & medicinal chemistry. 2010 Nov; 18(22):7873-7. doi: 10.1016/j.bmc.2010.09.044. [PMID: 20943395]
  • Sol Cristians, José A Guerrero-Analco, Araceli Pérez-Vásquez, Francisco Palacios-Espinosa, Carlos Ciangherotti, Robert Bye, Rachel Mata. Hypoglycemic activity of extracts and compounds from the leaves of Hintonia standleyana and H. latiflora: potential alternatives to the use of the stem bark of these species. Journal of natural products. 2009 Mar; 72(3):408-13. doi: 10.1021/np800642d. [PMID: 19140696]
  • José L López-Pérez, Dionisio A Olmedo, Esther Del Olmo, Yelkaira Vásquez, Pablo N Solís, Mahabir P Gupta, Arturo San Feliciano. Cytotoxic 4-phenylcoumarins from the leaves of Marila pluricostata. Journal of natural products. 2005 Mar; 68(3):369-73. doi: 10.1021/np049642g. [PMID: 15787438]
  • K Jenett-Siems, I Köhler, C Kraft, G Beyer, M F Melzig, E Eich. Cytotoxic constituents from Exostema mexicanum and Artemisia afra, two traditionally used plant remedies. Die Pharmazie. 2002 May; 57(5):351-2. doi: ". [PMID: 12061265]
  • M Itoigawa, C Ito, H T Tan, M Kuchide, H Tokuda, H Nishino, H Furukawa. Cancer chemopreventive agents, 4-phenylcoumarins from Calophyllum inophyllum. Cancer letters. 2001 Aug; 169(1):15-9. doi: 10.1016/s0304-3835(01)00521-3. [PMID: 11410320]
  • H Tawada, H Natsugari, E Ishikawa, Y Sugiyama, H Ikeda, K Meguro. Synthesis of 3-ureido derivatives of coumarin and 2-quinolone as potent acyl-CoA: cholesterol acyltransferase inhibitors. Chemical & pharmaceutical bulletin. 1995 Apr; 43(4):616-25. doi: 10.1248/cpb.43.616. [PMID: 7600615]