Broussonol E (BioDeep_00000266490)

   

PANOMIX_OTCML-2023


代谢物信息卡片


2- [ 3,4-Dihydroxy-5- (3-methyl-2-butenyl) phenyl ] -3,5,7-trihydroxy-6- (3-methyl-2-butenyl) -4H-1-benzopyran-4-one

化学式: C25H26O7 (438.1678446)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c(c1)(c(c(cc(C(=C(O)3)Oc(c2C(=O)3)cc(O)c(c(O)2)CC=C(C)C)1)O)O)CC=C(C)C
InChI: InChI=1S/C25H26O7/c1-12(2)5-7-14-9-15(10-18(27)21(14)28)25-24(31)23(30)20-19(32-25)11-17(26)16(22(20)29)8-6-13(3)4/h5-6,9-11,26-29,31H,7-8H2,1-4H3

描述信息

Papyriflavonol A is a pentahydroxyflavone that is flavone substituted with hydroxy groups at positions 3, 5, 7, 3 and 4 and prenyl groups at positions 6 and 5. Isolated from Broussonetia papyrifera, it exhibits inhibitory activity against phospholipase A2 and tyrosinase. It has a role as a metabolite, an EC 3.1.1.4 (phospholipase A2) inhibitor and an EC 1.14.18.1 (tyrosinase) inhibitor. It is a member of flavonols, a pentahydroxyflavone and a 3-hydroxyflavonoid.
Broussonol E is a natural product found in Broussonetia papyrifera and Broussonetia kazinoki with data available.
A pentahydroxyflavone that is flavone substituted with hydroxy groups at positions 3, 5, 7, 3 and 4 and prenyl groups at positions 6 and 5. Isolated from Broussonetia papyrifera, it exhibits inhibitory activity against phospholipase A2 and tyrosinase.

同义名列表

10 个代谢物同义名

2-(3,4-Dihydroxy-5-(3-methylbut-2-en-1-yl)phenyl)-3,5,7-trihydroxy-6-(3-methylbut-2-en-1-yl)-4H-chromen-4-one; 2-[3,4-dihydroxy-5-(3-methylbut-2-en-1-yl)phenyl]-3,5,7-trihydroxy-6-(3-methylbut-2-en-1-yl)-4H-chromen-4-one; 2-[3,4-dihydroxy-5-(3-methylbut-2-enyl)phenyl]-3,5,7-trihydroxy-6-(3-methylbut-2-enyl)chromen-4-one; 5,7,3,4-tetrahydroxy-6,5-di-(gamma,gamma-dimethylallyl)-flavonol; 5,7,3,4-tetrahydroxy-6,5-di-(gamma,gammadimethylallyl)-flavonol; 3,5,7,3,4-pentahydroxy-6,5-di-(3-methyl-2-butenyl)flavone; papyriflavonol A; Broussonol E; 2- [ 3,4-Dihydroxy-5- (3-methyl-2-butenyl) phenyl ] -3,5,7-trihydroxy-6- (3-methyl-2-butenyl) -4H-1-benzopyran-4-one; 2-[3,4-Dihydroxy-5-(3-methyl-2-butenyl)phenyl]-3,5,7-trihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Namrta Choudhry, Xin Zhao, Dan Xu, Mark Zanin, Weisan Chen, Zifeng Yang, Jianxin Chen. Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Journal of medicinal chemistry. 2020 11; 63(22):13205-13227. doi: 10.1021/acs.jmedchem.0c00626. [PMID: 32845145]
  • Ho-Yong Sohn, Chong-Suk Kwon, Kun-Ho Son. Fungicidal effect of prenylated flavonol, papyriflavonol A, isolated from Broussonetia papyrifera (L.) vent. against Candida albicans. Journal of microbiology and biotechnology. 2010 Oct; 20(10):1397-402. doi: 10.4014/jmb.1007.07026. [PMID: 21030824]
  • Wie Jong Kwak, Tae Churl Moon, Chang Xiu Lin, Hyeun Gee Rhyn, Hyejin Jung, Eunkyung Lee, Dong Yeul Kwon, Kun Ho Son, Hyun Pyo Kim, Sam Sik Kang, Makoto Murakami, Ichiro Kudo, Hyeun Wook Chang. Papyriflavonol A from Broussonetia papyrifera inhibits the passive cutaneous anaphylaxis reaction and has a secretory phospholipase A2-inhibitory activity. Biological & pharmaceutical bulletin. 2003 Mar; 26(3):299-302. doi: 10.1248/bpb.26.299. [PMID: 12612436]
  • P C Zhang, S Wang, Y Wu, R Y Chen, D Q Yu. Five new diprenylated flavonols from the leaves of Broussonetia kazinoki. Journal of natural products. 2001 Sep; 64(9):1206-9. doi: 10.1021/np010283o. [PMID: 11575957]
  • K H Son, S J Kwon, H W Chang, H P Kim, S S Kang. Papyriflavonol A, a new prenylated flavonol from Broussonetia papyrifera. Fitoterapia. 2001 May; 72(4):456-8. doi: 10.1016/s0367-326x(00)00329-4. [PMID: 11395279]