pongapin (BioDeep_00000266314)

PANOMIX_OTCML-2023 natural product

代谢物信息卡片

3-Methoxy-2-[3,4-(methylenedioxy)phenyl]-4H-furo[2,3-h]-1-benzopyran-4-one

化学式: C19H12O6 (336.0634)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c12ccc3c(c1cco2)oc(c(c3=O)OC)c1cc2c(cc1)OCO2
InChI: InChI=1S/C19H12O6/c1-21-19-16(20)12-3-5-13-11(6-7-22-13)18(12)25-17(19)10-2-4-14-15(8-10)24-9-23-14/h2-8H,9H2,1H3

描述信息

同义名列表

3 个代谢物同义名

pongapin; 3-Methoxy-2-[3,4-(methylenedioxy)phenyl]-4H-furo[2,3-h]-1-benzopyran-4-one; 2-(1,3-Benzodioxol-5-yl)-3-methoxy-4H-furo[2,3-h]-1-benzopyran-4-one

数据库引用编号

7 个数据库交叉引用编号

PubChem: 3083586
Metlin: METLIN49981
LipidMAPS: LMPK12111562
KNApSAcK: C00005092
CAS: 481-99-2
PMhub: MS000198255
LOTUS: LTS0157631

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

25 个相关的物种来源信息

2759 - Eukaryota: LTS0157631
3803 - Fabaceae: LTS0157631
3925 - Lonchocarpus: LTS0157631
681455 - Lonchocarpus heptaphyllus: 10.1016/S0031-9422(00)00300-9
681455 - Lonchocarpus heptaphyllus: LTS0157631
3398 - Magnoliopsida: LTS0157631
53625 - Millettia: LTS0157631
56064 - Pongamia: LTS0157631
56065 - Pongamia pinnata: 10.1007/978-1-4757-2351-9_13
56065 - Pongamia pinnata: 10.1016/0031-9422(82)83183-X
56065 - Pongamia pinnata: 10.1016/0031-9422(83)80254-4
56065 - Pongamia pinnata: 10.1016/0031-9422(91)80130-S
56065 - Pongamia pinnata: 10.1016/J.BMC.2009.05.051
56065 - Pongamia pinnata: 10.1016/J.BMCL.2014.11.015
56065 - Pongamia pinnata: 10.1016/J.PHYTOCHEM.2003.09.011
56065 - Pongamia pinnata: 10.1016/J.PHYTOCHEM.2006.05.016
56065 - Pongamia pinnata: 10.1016/S0031-9422(00)80118-1
56065 - Pongamia pinnata: 10.1021/NP50030A020
56065 - Pongamia pinnata: 10.1248/CPB.39.1473
56065 - Pongamia pinnata: 10.1248/CPB.58.1549
56065 - Pongamia pinnata: 10.3390/11100786
56065 - Pongamia pinnata: LTS0157631
35493 - Streptophyta: LTS0157631
58023 - Tracheophyta: LTS0157631
33090 - Viridiplantae: LTS0157631

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表

文献列表

Rituparna Roy, Debolina Pal, Subhayan Sur, Suvra Mandal, Prosenjit Saha, Chinmay Kumar Panda. Pongapin and Karanjin, furanoflavanoids of Pongamia pinnata, induce G2/M arrest and apoptosis in cervical cancer cells by differential reactive oxygen species modulation, DNA damage, and nuclear factor kappa-light-chain-enhancer of activated B cell signaling. Phytotherapy research : PTR. 2019 Apr; 33(4):1084-1094. doi: 10.1002/ptr.6302. [PMID: 30834631]
Rajni Sharma, Ibidapo S Williams, Linda Gatchie, Vinay R Sonawane, Bhabatosh Chaudhuri, Sandip B Bharate. Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in CYP1A1-overexpressing breast cancer cells. Bioorganic & medicinal chemistry. 2018 12; 26(23-24):6076-6086. doi: 10.1016/j.bmc.2018.11.013. [PMID: 30448188]
Jiayuan Li, Zhe Jiang, Xuezheng Li, Yue Hou, Fen Liu, Ning Li, Xia Liu, Lihua Yang. Natural therapeutic agents for neurodegenerative diseases from a traditional herbal medicine Pongamia pinnata (L.) Pierre. Bioorganic & medicinal chemistry letters. 2015 Jan; 25(1):53-8. doi: 10.1016/j.bmcl.2014.11.015. [PMID: 25466192]
Anindita Ghosh, Suvra Mandal, Avijit Banerji, Julie Banerji. A new biflavonyloxymethane from Pongamia pinnata. Natural product communications. 2010 Aug; 5(8):1213-4. doi: ". [PMID: 20839621]
R Ranga Rao, Ashok K Tiwari, P Prabhakar Reddy, K Suresh Babu, Amtul Z Ali, K Madhusudana, J Madhusudana Rao. New furanoflavanoids, intestinal alpha-glucosidase inhibitory and free-radical (DPPH) scavenging, activity from antihyperglycemic root extract of Derris indica (Lam.). Bioorganic & medicinal chemistry. 2009 Jul; 17(14):5170-5. doi: 10.1016/j.bmc.2009.05.051. [PMID: 19515570]
Hao Yin, Si Zhang, Jun Wu. [Study on flavonoids from stem bark of Pongamia pinnata]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2004 Jul; 27(7):493-5. doi: ". [PMID: 15551964]