Lactobionic acid (BioDeep_00000265332)

   

natural product PANOMIX_OTCML-2023


代谢物信息卡片


Lactobionic acid

化学式: C12H22O12 (358.1111212)
中文名称: 乳糖酸
谱图信息: 最多检出来源 Viridiplantae(plant) 1.68%

分子结构信息

SMILES: C(C1C(C(C(C(O1)OC(C(CO)O)C(C(C(=O)O)O)O)O)O)O)O
InChI: InChI=1S/C12H22O12/c13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h3-10,12-20H,1-2H2,(H,21,22)/t3-,4-,5+,6+,7-,8-,9-,10-,12+/m1/s1

描述信息

Lactobionic acid is a bionic acid naturally found in the Caspian Sea yogurt and chemically constituted of a gluconic acid bonded to a galactose. Lactobionic acid has antioxidant, antimicrobial, chelating, stabilizer, acidulant, and moisturizing properties[1].

同义名列表

1 个代谢物同义名

Lactobionic acid



数据库引用编号

21 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

9 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Kamila Goderska, Sonia Agudo Pena. An in vitro gastrointestinal model to evaluate the tolerance of encapsulated Lactobacillus and Lactococcus strains with synbiotic containing lactobionic acid via lyophilization technique to harsh gastric conditions during storage time. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2024 Apr; 197(?):114147. doi: 10.1016/j.ejpb.2023.11.012. [PMID: 37967725]
  • Adam Poltorak, Xin Zhou, Takao Kasuga, Yong Xu, Zhiliang Fan. Conversion of Deproteinized Cheese Whey to Lactobionate by an Engineered Neurospora crassa Strain F5. Applied biochemistry and biotechnology. 2024 Mar; 196(3):1292-1303. doi: 10.1007/s12010-023-04583-x. [PMID: 37392323]
  • Deepa U Warrier, Anantha K Dhanabalan, Gunasekaran Krishnasamy, Henry Kolge, Vandana Ghormade, Chandan R Gupta, Premlata K Ambre, Ujwala A Shinde. Novel derivatives of arabinogalactan, pullulan & lactobionic acid for targeting asialoglycoprotein receptor: Biomolecular interaction, synthesis & evaluation. International journal of biological macromolecules. 2022 May; 207(?):683-699. doi: 10.1016/j.ijbiomac.2022.02.176. [PMID: 35248606]
  • Shaigan Naidoo, Aliscia Daniels, Saffiya Habib, Moganavelli Singh. Poly-L-Lysine-Lactobionic Acid-Capped Selenium Nanoparticles for Liver-Targeted Gene Delivery. International journal of molecular sciences. 2022 Jan; 23(3):. doi: 10.3390/ijms23031492. [PMID: 35163414]
  • Kamila Goderska, Patryk Kozłowski. Evaluation of Microencapsulated Synbiotic Preparations Containing Lactobionic Acid. Applied biochemistry and biotechnology. 2021 Nov; 193(11):3483-3495. doi: 10.1007/s12010-021-03622-9. [PMID: 34282567]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Muhammad Kawish, Tooba Jabri, Abdelbary Elhissi, Hina Zahid, Kanwal Muhammad Iqbal, Komal Rao, Jasra Gul, Muhammad Abdullah, Muhammad Raza Shah. Galactosylated iron oxide nanoparticles for enhancing oral bioavailability of ceftriaxone. Pharmaceutical development and technology. 2021 Mar; 26(3):291-301. doi: 10.1080/10837450.2020.1866602. [PMID: 33475034]
  • Amr Hefnawy, Islam H Khalil, Kholoud Arafa, Marwan Emara, Ibrahim M El-Sherbiny. Dual-Ligand Functionalized Core-Shell Chitosan-Based Nanocarrier for Hepatocellular Carcinoma-Targeted Drug Delivery. International journal of nanomedicine. 2020; 15(?):821-837. doi: 10.2147/ijn.s240359. [PMID: 32103939]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Pei Zhou, Shuang Wu, Mohammad Hegazy, Hong Li, Xueju Xu, He Lu, Xin Huang. Engineered borate ester conjugated protein-polymer nanoconjugates for pH-responsive drug delivery. Materials science & engineering. C, Materials for biological applications. 2019 Nov; 104(?):109914. doi: 10.1016/j.msec.2019.109914. [PMID: 31500030]
  • Xiaoli Song, Juan Wang, Yue Xu, Hongxia Shao, Jun Gu. Surface-modified PLGA nanoparticles with PEG/LA-chitosan for targeted delivery of arsenic trioxide for liver cancer treatment: Inhibition effects enhanced and side effects reduced. Colloids and surfaces. B, Biointerfaces. 2019 Aug; 180(?):110-117. doi: 10.1016/j.colsurfb.2019.04.036. [PMID: 31030022]
  • Kamila Goderska. The antioxidant and prebiotic properties of lactobionic acid. Applied microbiology and biotechnology. 2019 May; 103(9):3737-3751. doi: 10.1007/s00253-019-09754-7. [PMID: 30919101]
  • L Lin, M Wong, H C Deeth, H E Oh. Calcium-induced skim milk gels using different calcium salts. Food chemistry. 2018 Apr; 245(?):97-103. doi: 10.1016/j.foodchem.2017.10.081. [PMID: 29287467]
  • Dario Rusciano, Salvatore Pezzino, Melania Olivieri, Martina Cristaldi, Caterina Gagliano, Gabriella Lupo, Carmelina Daniela Anfuso. Age-Related Dry Eye Lactoferrin and Lactobionic Acid. Ophthalmic research. 2018; 60(2):94-99. doi: 10.1159/000489093. [PMID: 29920480]
  • Quanbing Mou, Yuan Ma, Xinyuan Zhu, Deyue Yan. A small molecule nanodrug consisting of amphiphilic targeting ligand-chemotherapy drug conjugate for targeted cancer therapy. Journal of controlled release : official journal of the Controlled Release Society. 2016 05; 230(?):34-44. doi: 10.1016/j.jconrel.2016.03.037. [PMID: 27040815]
  • Kamila Goderska, Wojciech Juzwa, Artur Szwengiel, Zbigniew Czarnecki. Lactobionic acid production by glucose-fructose oxidoreductase from Zymomonas mobilis expressed in Escherichia coli. Biotechnology letters. 2015 Oct; 37(10):2047-53. doi: 10.1007/s10529-015-1887-0. [PMID: 26091863]
  • Kamila Goderska, Artur Szwengiel, Zbigniew Czarnecki. The utilization of Pseudomonas taetrolens to produce lactobionic acid. Applied biochemistry and biotechnology. 2014 Aug; 173(8):2189-97. doi: 10.1007/s12010-014-1024-x. [PMID: 24980748]
  • Xiaoli Song, Juan Wang, Xiadan Luo, Chunlan Xu, Aiping Zhu, Rong Guo, Caifeng Yan, Peizhi Zhu. Synthesis, biocompatible, and self-assembly properties of poly (ethylene glycol)/lactobionic acid-grafted chitosan. Journal of biomaterials science. Polymer edition. 2014 Jul; 25(10):1062-75. doi: 10.1080/09205063.2014.918465. [PMID: 24847798]
  • M Tasic-Kostov, D Pavlovic, M Lukic, I Jaksic, I Arsic, S Savic. Lactobionic acid as antioxidant and moisturizing active in alkyl polyglucoside-based topical emulsions: the colloidal structure, stability and efficacy evaluation. International journal of cosmetic science. 2012 Oct; 34(5):424-34. doi: 10.1111/j.1468-2494.2012.00732.x. [PMID: 22691034]
  • Jaleh Varshosaz, Farshid Hassanzadeh, Hojjat Sadeghi, Mostafa Khadem. Galactosylated nanostructured lipid carriers for delivery of 5-FU to hepatocellular carcinoma. Journal of liposome research. 2012 Sep; 22(3):224-36. doi: 10.3109/08982104.2012.662653. [PMID: 22385296]
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  • Kun Ma, Haijun Shen, Song Shen, Men Xie, Chuanbin Mao, Liyan Qiu, Yi Jin. Development of a successive targeting liposome with multi-ligand for efficient targeting gene delivery. The journal of gene medicine. 2011 May; 13(5):290-301. doi: 10.1002/jgm.1569. [PMID: 21574214]
  • Wenjiang Yang, Tiantian Mou, Wenyan Guo, Huihui Jing, Cheng Peng, Xianzhong Zhang, Yunchuan Ma, Boli Liu. Fluorine-18 labeled galactosylated chitosan for asialoglycoprotein-receptor-mediated hepatocyte imaging. Bioorganic & medicinal chemistry letters. 2010 Aug; 20(16):4840-4. doi: 10.1016/j.bmcl.2010.06.106. [PMID: 20634070]
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  • Wenyu Wang, Xiuli Zhao, Haiyang Hu, Dawei Chen, Jianchun Gu, Yihui Deng, Jin Sun. Galactosylated solid lipid nanoparticles with cucurbitacin B improves the liver targetability. Drug delivery. 2010 Apr; 17(3):114-22. doi: 10.3109/10717540903580176. [PMID: 20148709]
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