Spisulosine; Spisulosine 285 (BioDeep_00000263988)
代谢物信息卡片
化学式: C18H39NO (285.3031)
中文名称:
谱图信息:
最多检出来源 Mentha canadensis(plant) 100%
分子结构信息
SMILES: CCCCCCCCCCCCCCCC(C(C)N)O
InChI: InChI=1S/C18H39NO/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20)17(2)19/h17-18,20H,3-16,19H2,1-2H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Gergely Karsai, Museer Lone, Zoltán Kutalik, J Thomas Brenna, Hongde Li, Duojia Pan, Arnold von Eckardstein, Thorsten Hornemann. FADS3 is a Δ14Z sphingoid base desaturase that contributes to gender differences in the human plasma sphingolipidome.
The Journal of biological chemistry.
2020 02; 295(7):1889-1897. doi:
10.1074/jbc.ac119.011883. [PMID: 31862735] - Nancy Wei, Jessica Pan, Rodica Pop-Busui, Alaa Othman, Irina Alecu, Thorsten Hornemann, Florian S Eichler. Altered sphingoid base profiles in type 1 compared to type 2 diabetes.
Lipids in health and disease.
2014 Oct; 13(?):161. doi:
10.1186/1476-511x-13-161. [PMID: 25305670] - Richard A Zuellig, Thorsten Hornemann, Alaa Othman, Adrian B Hehl, Heiko Bode, Tanja Güntert, Omolara O Ogunshola, Enrica Saponara, Kamile Grabliauskaite, Jae-Hwi Jang, Udo Ungethuem, Yu Wei, Arnold von Eckardstein, Rolf Graf, Sabrina Sonda. Deoxysphingolipids, novel biomarkers for type 2 diabetes, are cytotoxic for insulin-producing cells.
Diabetes.
2014 Apr; 63(4):1326-39. doi:
10.2337/db13-1042. [PMID: 24379346] - Annelies Rotthier, Anke Penno, Bernd Rautenstrauss, Michaela Auer-Grumbach, Georg M Stettner, Bob Asselbergh, Kim Van Hoof, Heinrich Sticht, Nicolas Lévy, Vincent Timmerman, Thorsten Hornemann, Katrien Janssens. Characterization of two mutations in the SPTLC1 subunit of serine palmitoyltransferase associated with hereditary sensory and autonomic neuropathy type I.
Human mutation.
2011 Jun; 32(6):E2211-25. doi:
10.1002/humu.21481. [PMID: 21618344] - Ellen Stokvis, Hilde Rosing, Luis López-Lázaro, Jan H M Schellens, Jos H Beijnen. A more sensitive MS detector does not obviously lead to a more sensitive assay: experiences with ES-285.
Biomedical chromatography : BMC.
2004 Jul; 18(6):403-7. doi:
10.1002/bmc.404. [PMID: 15273982] - C Maraschiello, E Miranda, E Millán, P Floriano, J Vilageliu. Phenylisothiocyanate and dansyl chloride precolumn derivatizations for the high-performance liquid chromatography analysis of the antitumoral agent ES-285 in dog plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2003 Jul; 791(1-2):1-11. doi:
10.1016/s1570-0232(03)00161-2. [PMID: 12798159] - E Stokvis, L Nan-Offeringa, H Rosing, L López-Lázaro, J L Aceña, E Miranda, A Lyubimov, B S Levine, C D'Aleo, J H M Schellens, J H Beijnen. Quantitative analysis of ES-285, an investigational marine anticancer drug, in human, mouse, rat, and dog plasma using coupled liquid chromatography and tandem mass spectrometry.
Journal of mass spectrometry : JMS.
2003 May; 38(5):548-54. doi:
10.1002/jms.469. [PMID: 12794877] - R J Winchester, C Y Wang, J Halper, T Hoffman. Studies with B-cell allo- and hetero-antisera: parallel reactivity and special properties.
Scandinavian journal of immunology.
1976; 5(6-7):745-57. doi:
10.1111/j.1365-3083.1976.tb03024.x. [PMID: 62389]
