Guaiane (BioDeep_00000263028)
natural product
代谢物信息卡片
Guaiane
化学式: C15H28 (208.2190888)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)C1CCC(C)C2CCC(C)C2C1
InChI: InChI=1S/C15H28/c1-10(2)13-7-5-11(3)14-8-6-12(4)15(14)9-13/h10-15H,5-9H2,1-4H3/t11-,12-,13+,14-,15-/m0/s1
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:36524
- PubChem: 9548703
- KNApSAcK: C00037222
- PMhub: MS000248802
- LOTUS: LTS0067800
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
9 个相关的物种来源信息
- 4200 - Caprifoliaceae: LTS0067800
- 2759 - Eukaryota: LTS0067800
- 3398 - Magnoliopsida: LTS0067800
- 59169 - Nardostachys: LTS0067800
- 179860 - Nardostachys jatamansi: 10.1016/S0031-9422(01)00469-1
- 179860 - Nardostachys jatamansi: LTS0067800
- 35493 - Streptophyta: LTS0067800
- 58023 - Tracheophyta: LTS0067800
- 33090 - Viridiplantae: LTS0067800
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xian-Jun Jiang, Yan Li, Xiang-Mei Li, Shi-Zhen Wen, Sai-Lei Yang, Guo-Zhu Wei, Chang-An Geng. Two new guaiane-type sesquiterpenes from Curcuma wenyujin.
Journal of Asian natural products research.
2024 Apr; 26(4):482-488. doi:
10.1080/10286020.2023.2249833. [PMID: 37610136] - Xiao-Feng He, Yun-Bao Ma, Tian-Ze Li, Ji-Jun Chen. Highly oxygenated guaiane-type sesquiterpene lactones from Artemisia sacrorum and their antihepatoma activity.
Phytochemistry.
2024 Jan; 217(?):113930. doi:
10.1016/j.phytochem.2023.113930. [PMID: 37993076] - Chong Shang, Yun-Bao Ma, Yuan Wang, Xiao-Feng He, Tian-Ze Li, Ji-Jun Chen. Artemongolins A-K, undescribed germacrane-guaiane sesquiterpenoid dimers from Artemisia mongolica and their antihepatoma activities.
Archives of pharmacal research.
2023 Oct; 46(9-10):782-794. doi:
10.1007/s12272-023-01466-x. [PMID: 37770811] - Ishaq Muhammad, Syed Shams Ul Hassan, Wen-Jing Xu, Guo-Li Tu, Hua-Jun Yu, Xue Xiao, Shi-Kai Yan, Hui-Zi Jin, Simona Bungau. An extensive pharmacological evaluation of novel anti-nociceptive and IL-6 targeted anti-inflammatory guaiane-type sesquiterpenoids from Cinnamomum migao H. W. Li through in-depth in-vitro, ADMET, and molecular docking studies.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2023 Aug; 164(?):114946. doi:
10.1016/j.biopha.2023.114946. [PMID: 37257229] - Mei-Zhu Wu, Bing-Quan Xu, Xiao-Zheng Zhang, Sha Liu, You-Ping Luo, Xue-Ming Zhou, Guang-Ying Chen. Guaiane-Type Sesquiterpenes from the Stems of Fissistigma oldhamii.
Chemistry & biodiversity.
2023 May; 20(5):e202300338. doi:
10.1002/cbdv.202300338. [PMID: 37019843] - Rui Guo, Zhi-Kang Duan, Qian Li, Guo-Dong Yao, Shao-Jiang Song, Xiao-Xiao Huang. Guide isolation of guaiane-type sesquiterpenoids from Daphne tangutica maxim. And their anti-inflammatory activities.
Phytochemistry.
2023 Feb; 206(?):113523. doi:
10.1016/j.phytochem.2022.113523. [PMID: 36442577] - Jae Sang Han, Jun Gu Kim, Thi Phuong Linh Le, Yong Beom Cho, Dongho Lee, Jin Tae Hong, Mi Kyeong Lee, Bang Yeon Hwang. Targeted isolation of sesquiterpene lactone dimers from Aucklandia lappa guided by LC-HRMS/MS-based molecular networking.
Phytochemistry.
2023 Feb; 206(?):113557. doi:
10.1016/j.phytochem.2022.113557. [PMID: 36496006] - Wei Dong, Tian-Ze Li, Xiao-Yan Huang, Xiao-Feng He, Chang-An Geng, Xue-Mei Zhang, Ji-Jun Chen. Artemzhongdianolides A1-A21, antihepatic fibrosis guaiane-type sesquiterpenoid dimers from Artemisia zhongdianensis.
Bioorganic chemistry.
2022 11; 128(?):106056. doi:
10.1016/j.bioorg.2022.106056. [PMID: 35908354] - Zhen Gao, Wen-Jing Ma, Tian-Ze Li, Yun-Bao Ma, Jing Hu, Xiao-Yan Huang, Chang-An Geng, Xiao-Feng He, Xue-Mei Zhang, Ji-Jun Chen. Artemidubolides A-T, cytotoxic unreported guaiane-type sesquiterpenoid dimers against three hepatoma cell lines from Artemisia dubia.
Phytochemistry.
2022 Oct; 202(?):113299. doi:
10.1016/j.phytochem.2022.113299. [PMID: 35809862] - Elena Serino, Giuseppina Chianese, Giorgia Musto, Gökhan Zengin, Daniela Rigano, Mariano Stornaiuolo, Carmen Formisano, Orazio Taglialatela-Scafati. Guaiane-rich phytochemical profile of Centaurea kotschyi subsp. persica (Boiss.) Wagenitz and identification of hypoglycaemic metabolites.
Phytochemistry.
2022 Jul; 199(?):113189. doi:
10.1016/j.phytochem.2022.113189. [PMID: 35427652] - Yahui Li, Jingwen Liu, Yingchun Wu, Yiming Li, Fujiang Guo. Guaiane-type sesquiterpenes from Curcumawenyujin.
Phytochemistry.
2022 Jun; 198(?):113164. doi:
10.1016/j.phytochem.2022.113164. [PMID: 35306002] - Young Sook Yun, Tomomi Nakano, Haruhiko Fukaya, Yukio Hitotsuyanagi, Miho Nakamura, Megumi Umetsu, Nobuko Matsushita, Katsunori Miyake, Hiroyuki Fuchino, Nobuo Kawahara, Fuki Moriya, Akihiro Ito, Yuji Takahashi, Hideshi Inoue. Retusone A, a Guaiane-Type Sesquiterpene Dimer from Wikstroemia retusa and Its Inhibitory Effects on Histone Acetyltransferase HBO1 Expression.
Molecules (Basel, Switzerland).
2022 May; 27(9):. doi:
10.3390/molecules27092909. [PMID: 35566260] - Xiang-Mei Tan, Qi Li, Yan-Duo Wang, Tie-Lin Wang, Jian Yang, Bing-Da Sun, Lan-Ping Guo, Gang Ding. UPLC-Q-TOF-MS/MS analysis of the guaiane sesquiterpenoids oxytropiols A-J and detection of undescribed analogues from the locoweed endophytic fungus Alternaria oxytropis (Pleosporaceae).
Phytochemical analysis : PCA.
2022 Apr; 33(3):344-354. doi:
10.1002/pca.3092. [PMID: 34755399] - Francisco J R Mejías, Inmaculada P Fernández, Carlos Rial, Rosa M Varela, José M G Molinillo, José J Calvino, Susana Trasobares, Francisco A Macías. Encapsulation of Cynara Cardunculus Guaiane-type Lactones in Fully Organic Nanotubes Enhances Their Phytotoxic Properties.
Journal of agricultural and food chemistry.
2022 Mar; 70(12):3644-3653. doi:
10.1021/acs.jafc.1c07806. [PMID: 35289164] - Ganghua Ma, Jiaying Chen, Luming Wang, Fei Qian, Guangxia Li, Xiaojun Wu, Liuqiang Zhang, Yiming Li. Eighteen structurally diversified sesquiterpenes isolated from Pogostemon cablin and their inhibitory effects on nitric oxide production.
Fitoterapia.
2022 Jan; 156(?):105098. doi:
10.1016/j.fitote.2021.105098. [PMID: 34883225] - Li-Hua Su, Yun-Bao Ma, Chang-An Geng, Tian-Ze Li, Xiao-Yan Huang, Jing Hu, Xin Zhang, Shuang Tang, Cheng Shen, Zhen Gao, Xue-Mei Zhang, Ji-Jun Chen. Artematrovirenins A-P, guaiane-type sesquiterpenoids with cytotoxicities against two hepatoma cell lines from Artemisia atrovirens.
Bioorganic chemistry.
2021 09; 114(?):105072. doi:
10.1016/j.bioorg.2021.105072. [PMID: 34144276] - Qi-Qi Xu, Chao Zhang, Ya-Long Zhang, Jian-Li Lei, Ling-Yi Kong, Jian-Guang Luo. Dimeric guaianes from leaves of Xylopia vielana as snail inhibitors identified by high content screening.
Bioorganic chemistry.
2021 03; 108(?):104646. doi:
10.1016/j.bioorg.2021.104646. [PMID: 33484941] - David M Cárdenas, Francisco J R Mejías, José M G Molinillo, Francisco A Macías. Synthesis of Vlasouliolides: A Pathway toward Guaiane-Eudesmane C17/C15 Dimers by Photochemical and Michael Additions.
The Journal of organic chemistry.
2020 06; 85(11):7322-7332. doi:
10.1021/acs.joc.0c00705. [PMID: 32349482] - Zhihui Liu, Mengyu Dong, Hang Chang, Na Han, Jun Yin. Guaiane type of sesquiterpene with NO inhibitory activity from the root of Wikstroemia indica.
Bioorganic chemistry.
2020 06; 99(?):103785. doi:
10.1016/j.bioorg.2020.103785. [PMID: 32222617] - Hui-Mei You, Juan-Rong Zhang, Zhi-Heng Zhao, Wei Wang, Li-Zhu Zhang, Yun-Tao Jiang, Ying Wang, Xiang-Zhong Huang, Zhi-Yong Jiang. [A new guaiane-type sesquiterpenoid from Croton yunnanensis].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2019 Nov; 44(21):4648-4652. doi:
10.19540/j.cnki.cjcmm.20190809.201. [PMID: 31872660] - Qiang Ren, Wen-Yu Zhao, Shao-Chun Shi, Feng-Ying Han, Ying-Ying Zhang, Qing-Bo Liu, Guo-Dong Yao, Bin Lin, Xiao-Xiao Huang, Shao-Jiang Song. Guaiane-Type Sesquiterpenoids from the Roots of Daphne genkwa and Evaluation of Their Neuroprotective Effects.
Journal of natural products.
2019 06; 82(6):1510-1517. doi:
10.1021/acs.jnatprod.8b01049. [PMID: 31150241] - Jun-Li Yang, Trong Tuan Dao, Tran Thi Hien, Ya-Min Zhao, Yan-Ping Shi. Further sesquiterpenoids from the rhizomes of Homalomena occulta and their anti-inflammatory activity.
Bioorganic & medicinal chemistry letters.
2019 05; 29(10):1162-1167. doi:
10.1016/j.bmcl.2019.03.031. [PMID: 30928195] - Fang-Fang Xiang, Jian-Wu He, Zhu-Xiang Liu, Qing-Zhong Peng, Hua Wei. Two new guaiane-type sesquiterpenes from Curcuma kwangsiensis and their inhibitory activity of nitric oxide production in lipopolysaccharide-stimulated macrophages.
Natural product research.
2018 Nov; 32(22):2670-2675. doi:
10.1080/14786419.2017.1378203. [PMID: 28931326] - Pattreeya Tungcharoen, Chatchai Wattanapiromsakul, Pimpimon Tansakul, Seikou Nakamura, Hisashi Matsuda, Supinya Tewtrakul. Antiinflammation constituents from Curcuma zedoaroides.
Phytotherapy research : PTR.
2018 Nov; 32(11):2312-2320. doi:
10.1002/ptr.6173. [PMID: 30109745] - Yang-Guo Xie, Yi-Gong Guo, Guo-Jing Wu, Sheng-Lan Zhu, Tao-Fang Cheng, Yu Zhang, Shi-Kai Yan, Hui-Zi Jin, Wei-Dong Zhang. Xylopsides A-D, four rare guaiane dimers with two unique bridged pentacyclic skeletons from Xylopia vielana.
Organic & biomolecular chemistry.
2018 09; 16(37):8408-8412. doi:
10.1039/c8ob01689e. [PMID: 30221279] - Lei Wang, Wen Qin, Li Tian, Xue-Xue Zhang, Fang Lin, Fan Cheng, Jian-Feng Chen, Cheng-Xiong Liu, Zhi-Yong Guo, Peter Proksch, Kun Zou. Caroguaianolide A-E, five new cytotoxic sesquiterpene lactones from Carpesium abrotanoides L.
Fitoterapia.
2018 Jun; 127(?):349-355. doi:
10.1016/j.fitote.2018.03.015. [PMID: 29621599] - Quan-Xiang Wu, Xiao-Feng He, Chun-Xiao Jiang, Wei Zhang, Zhuan-Ning Shi, Hong-Fang Li, Ying Zhu. Two novel bioactive sulfated guaiane sesquiterpenoid salt alkaloids from the aerial parts of Scorzonera divaricata.
Fitoterapia.
2018 Jan; 124(?):113-119. doi:
10.1016/j.fitote.2017.10.011. [PMID: 29066296] - Shengjuan Dong, Baocai Li, Weifeng Dai, Dong Wang, Yi Qin, Mi Zhang. Sesqui- and Diterpenoids from the Radix of Curcuma aromatica.
Journal of natural products.
2017 12; 80(12):3093-3102. doi:
10.1021/acs.jnatprod.6b01100. [PMID: 29236488] - Carmen Formisano, Carmina Sirignano, Daniela Rigano, Giuseppina Chianese, Gokhan Zengin, Ean-Jeong Seo, Thomas Efferth, Orazio Taglialatela-Scafati. Antiproliferative activity against leukemia cells of sesquiterpene lactones from the Turkish endemic plant Centaurea drabifolia subsp. detonsa.
Fitoterapia.
2017 Jul; 120(?):98-102. doi:
10.1016/j.fitote.2017.05.016. [PMID: 28579551] - Zhi-Guo Zhuo, Guo-Zhen Wu, Xin Fang, Xin-Hui Tian, Hong-Yuan Dong, Xi-Ke Xu, Hui-Liang Li, Ning Xie, Wei-Dong Zhang, Yun-Heng Shen. Chlorajaponols A-F, sesquiterpenoids from Chloranthus japonicus and their in vitro anti-inflammatory and anti-tumor activities.
Fitoterapia.
2017 Jun; 119(?):90-99. doi:
10.1016/j.fitote.2017.04.009. [PMID: 28408269] - Xue-Ming Zhou, Cai-Juan Zheng, Yu-Qin Zhang, Xiao-Peng Zhang, Xiao-Ping Song, Wei Xu, Guang-Ying Chen. Guaiane-Type Sesquiterpenoids from Fissistigma oldhamii Inhibit the Proliferation of Synoviocytes.
Planta medica.
2017 Feb; 83(3-04):217-223. doi:
10.1055/s-0042-111440. [PMID: 27405108] - Xing-De Wu, Lin-Fen Ding, Wen-Chao Tu, Hui Yang, Jia Su, Li-Yan Peng, Yan Li, Qin-Shi Zhao. Bioactive sesquiterpenoids from the flowers of Inula japonica.
Phytochemistry.
2016 Sep; 129(?):68-76. doi:
10.1016/j.phytochem.2016.07.008. [PMID: 27452450] - Yang Yu, Li-She Gan, Sheng-Ping Yang, Li Sheng, Qun-Fang Liu, Shao-Nong Chen, Jia Li, Jian-Min Yue. Eucarobustols A-I, Conjugates of Sesquiterpenoids and Acylphloroglucinols from Eucalyptus robusta.
Journal of natural products.
2016 05; 79(5):1365-72. doi:
10.1021/acs.jnatprod.6b00090. [PMID: 27142786] - Yong-Jin Yang, Juan Yao, Xiao-Jie Jin, Zhuan-Ning Shi, Tian-Fei Shen, Jian-Guo Fang, Xiao-Jun Yao, Ying Zhu. Sesquiterpenoids and tirucallane triterpenoids from the roots of Scorzonera divaricata.
Phytochemistry.
2016 Apr; 124(?):86-98. doi:
10.1016/j.phytochem.2016.01.015. [PMID: 26832425] - Li-Yan Peng, Gang Xu, Juan He, Xing-De Wu, Liao-Bin Dong, Xiu Gao, Xiao Cheng, Jia Su, Yan Li, Wen-Ming Dong, Qin-Shi Zhao. Nor-lupane triterpenoid and guaiane sesquiterpenoids from Schefflera venulosa.
Fitoterapia.
2015 Jun; 103(?):294-8. doi:
10.1016/j.fitote.2015.05.005. [PMID: 25964186] - Antoaneta Trendafilova, Milka Todorova, Viktoriya Genova, Pavletta Shestakova, Dimitar Dimitrov, Milka Jadranine, Slobodan Milosavljevic. New pseudoguaiane derivatives from Inula aschersoniana Janka var. aschersoniana.
Natural product communications.
2014 Aug; 9(8):1123-4. doi:
". [PMID: 25233586] - Marcos D P Pereira, Tito da Silva, Lucia M X Lopes, Antoniana U Krettli, Lucas S Madureira, Julio Zukerman-Schpector. 4,5-seco-guaiane and a nine-membered sesquiterpene lactone from Holostylis reniformis.
Molecules (Basel, Switzerland).
2012 Nov; 17(12):14046-57. doi:
10.3390/molecules171214046. [PMID: 23187288] - Ken-ichi Nakashima, Masayoshi Oyama, Tetsuro Ito, Joko Ridho Witono, Dedy Darnaedi, Toshiyuki Tanaka, Jin Murata, Munekazu Iinuma. Novel zierane- and guaiane-type sesquiterpenes from the root of Melicope denhamii.
Chemistry & biodiversity.
2012 Oct; 9(10):2195-202. doi:
10.1002/cbdv.201100345. [PMID: 23081919] - Norma Hussin, Luigi Mondello, Rosaria Costa, Paola Dugo, Nik Idris Nik Yusoff, Mohd Ambar Yarmo, Ahmad AbWahab, Mamot Said. Quantitative and physical evaluation of patchouli essential oils obtained from different sources of Pogostemon cablin.
Natural product communications.
2012 Jul; 7(7):927-30. doi:
". [PMID: 22908584] - Jing Xu, Eduardo J E Caro-Diaz, Ayse Batova, Steven D E Sullivan, Emmanuel A Theodorakis. Formal synthesis of (-)-englerin A and cytotoxicity studies of truncated englerins.
Chemistry, an Asian journal.
2012 May; 7(5):1052-60. doi:
10.1002/asia.201101021. [PMID: 22415793] - Rhone K Akee, Tanya Ransom, Ranjala Ratnayake, James B McMahon, John A Beutler. Chlorinated englerins with selective inhibition of renal cancer cell growth.
Journal of natural products.
2012 Mar; 75(3):459-63. doi:
10.1021/np200905u. [PMID: 22280462] - Cheng-Hung Lee, Chia-Ying Kao, Shih-Yao Kao, Chih-Han Chang, Jui-Hsin Su, Tsong-Long Hwang, Yueh-Hsiung Kuo, Zhi-Hong Wen, Ping-Jyun Sung. Terpenoids from the octocorals Menella sp. (Plexauridae) and Lobophytum crassum (Alcyonacea).
Marine drugs.
2012 Feb; 10(2):427-438. doi:
10.3390/md10020427. [PMID: 22412810] - Damian Paul Drew, Søren K Rasmussen, Pinarosa Avato, Henrik Toft Simonsen. A comparison of headspace solid-phase microextraction and classic hydrodistillation for the identification of volatile constituents from Thapsia spp. provides insights into guaianolide biosynthesis in Apiaceae.
Phytochemical analysis : PCA.
2012 Jan; 23(1):44-51. doi:
10.1002/pca.1323. [PMID: 21618308] - Jun-Li Yang, Yan-Ping Shi. Structurally diverse terpenoids from the rhizomes of Cyperus rotundus L.
Planta medica.
2012 Jan; 78(1):59-64. doi:
10.1055/s-0031-1280216. [PMID: 21928169] - Akram Ziaei, Zahra Amirghofran, Josef Zapp, Mohammad Ramezani. Immunoinhibitory effect of teuclatriol a guaiane sesquiterpene from Salvia mirzayanii.
Iranian journal of immunology : IJI.
2011 Dec; 8(4):226-35. doi:
ijiv8i4a5. [PMID: 22201620] - Xiangrong Cheng, Qi Zeng, Jie Ren, Jiangjiang Qin, Shoude Zhang, Yunheng Shen, Jiaxian Zhu, Fei Zhang, Ruijie Chang, Yan Zhu, Weidong Zhang, Huizi Jin. Sesquiterpene lactones from Inula falconeri, a plant endemic to the Himalayas, as potential anti-inflammatory agents.
European journal of medicinal chemistry.
2011 Nov; 46(11):5408-15. doi:
10.1016/j.ejmech.2011.08.047. [PMID: 21924800] - Peng-Cheng Wang, Xin-Hui Ran, Rui Chen, Huai-Rong Luo, Qing-Yun Ma, Yu-Qing Liu, Jiang-Miao Hu, Sheng-Zhuo Huang, He-Zhong Jiang, Zhong-Quan Chen, Jun Zhou, You-Xing Zhao. Sesquiterpenoids and lignans from the roots of Valeriana officinalis L.
Chemistry & biodiversity.
2011 Oct; 8(10):1908-13. doi:
10.1002/cbdv.201000247. [PMID: 22006719] - Mareike Maas, Alexandra M Deters, Andreas Hensel. Anti-inflammatory activity of Eupatorium perfoliatum L. extracts, eupafolin, and dimeric guaianolide via iNOS inhibitory activity and modulation of inflammation-related cytokines and chemokines.
Journal of ethnopharmacology.
2011 Sep; 137(1):371-81. doi:
10.1016/j.jep.2011.05.040. [PMID: 21669270] - Zhenwu Li, Mika Nakashige, William J Chain. A brief synthesis of (-)-englerin A.
Journal of the American Chemical Society.
2011 May; 133(17):6553-6. doi:
10.1021/ja201921j. [PMID: 21476574] - Lea Radtke, Matthieu Willot, Hongyan Sun, Slava Ziegler, Stephanie Sauerland, Carsten Strohmann, Roland Fröhlich, Peter Habenberger, Herbert Waldmann, Mathias Christmann. Total synthesis and biological evaluation of (-)-englerin A and B: synthesis of analogues with improved activity profile.
Angewandte Chemie (International ed. in English).
2011 Apr; 50(17):3998-4002. doi:
10.1002/anie.201007790. [PMID: 21472928] - Ki Hyun Kim, Jung Wook Choi, Sang Un Choi, Sang Keun Ha, Sun Yeou Kim, Hee-Juhn Park, Kang Ro Lee. The chemical constituents of Piper kadsura and their cytotoxic and anti-neuroinflammtaory activities.
Journal of enzyme inhibition and medicinal chemistry.
2011 Apr; 26(2):254-60. doi:
10.3109/14756366.2010.496363. [PMID: 20687793] - Osamu Shirota, Jennifer M Oribello, Setsuko Sekita, Motoyoshi Satake. Sesquiterpenes from Blumea balsamifera.
Journal of natural products.
2011 Mar; 74(3):470-6. doi:
10.1021/np100646n. [PMID: 21319848] - Mi-Ran Cha, Yeon Hee Choi, Chun Whan Choi, Dae Seok Yoo, Young Sup Kim, Sang Un Choi, Young Ho Kim, Shi Yong Ryu. New guaiane sesquiterpene lactones from Ixeris dentata.
Planta medica.
2011 Mar; 77(4):380-2. doi:
10.1055/s-0030-1250369. [PMID: 20890810] - S Saeidnia, Ar Gohari, N Mokhber-Dezfuli, F Kiuchi. A review on phytochemistry and medicinal properties of the genus Achillea.
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences.
2011; 19(3):173-86. doi:
". [PMID: 22615655] - Bruna Polacchine da Silva, Diogenes Aparício Cortez, Thaisa Yume Violin, Benedito Prado Dias Filho, Celso Vataru Nakamura, Tânia Ueda-Nakamura, Izabel Cristina Piloto Ferreira. Antileishmanial activity of a guaianolide from Tanacetum parthenium (L.) Schultz Bip.
Parasitology international.
2010 Dec; 59(4):643-6. doi:
10.1016/j.parint.2010.08.005. [PMID: 20732450] - Niko S Radulović, Milan S Dekić, Zorica Z Stojanović-Radić, Suad K Zoranić. Geranium macrorrhizum L. (Geraniaceae) essential oil: a potent agent against Bacillus subtilis.
Chemistry & biodiversity.
2010 Nov; 7(11):2783-800. doi:
10.1002/cbdv.201000100. [PMID: 21072778] - Hong-wei Fu, Lin Zhang, Tao Yi, Yu-lin Feng, Jing-kui Tian. Two new guaiane-type sesquiterpenoids from the fruits of Daucus carota L.
Fitoterapia.
2010 Jul; 81(5):443-6. doi:
10.1016/j.fitote.2009.12.008. [PMID: 20060880] - Weihuan Huang, Xiaoli Zhang, Yifei Wang, Wencai Ye, Vincent Ec Ooi, Hau Yin Chung, Yaolan Li. Antiviral biflavonoids from Radix Wikstroemiae (Liaogewanggen).
Chinese medicine.
2010 Jun; 5(?):23. doi:
10.1186/1749-8546-5-23. [PMID: 20565950] - K C Nicolaou, Qiang Kang, Sin Yee Ng, David Y-K Chen. Total synthesis of englerin A.
Journal of the American Chemical Society.
2010 Jun; 132(23):8219-22. doi:
10.1021/ja102927n. [PMID: 20496885] - Tim G Elford, Dennis G Hall. Total synthesis of (+)-chinensiolide B via tandem allylboration/lactonization.
Journal of the American Chemical Society.
2010 Feb; 132(5):1488-9. doi:
10.1021/ja9104478. [PMID: 20067261] - Juan J Rubal, F Javier Moreno-Dorado, Francisco M Guerra, Zacarías D Jorge, María del Carmen Galán, Ginés M Salido, Søren B Christensen, Helmer Søhoel, Guillermo M Massanet. A phenylpropanoid, a slovenolide, two sulphur-containing germacranes and Ca2+-ATPase inhibitors from Thapsia villosa.
Planta medica.
2010 Feb; 76(3):284-90. doi:
10.1055/s-0029-1186056. [PMID: 19708003] - Ivan Vucković, Ljubodrag Vujisić, Danijela Stesević, Sinisa Radulović, Milan Lazić, Slobodan Milosavljević. Cytotoxic guaianolide from Anthemis segetalis (Asteraceae).
Phytotherapy research : PTR.
2010 Feb; 24(2):225-7. doi:
10.1002/ptr.2916. [PMID: 19585474] - Cheong-Yong Yun, Dongchun Kim, Won-Hee Lee, Yu Mi Park, Seung Ho Lee, Minkyun Na, Yurngdong Jahng, Bang Yeon Hwang, Mi Kyeong Lee, Sang-Bae Han, Youngsoo Kim. Torilin from Torilis japonica inhibits melanin production in alpha-melanocyte stimulating hormone-activated B16 melanoma cells.
Planta medica.
2009 Nov; 75(14):1505-8. doi:
10.1055/s-0029-1185803. [PMID: 19533579] - Akram Ghantous, Niveen Nasser, Ihab Saab, Nadine Darwiche, Najat A Saliba. Structure-activity relationship of seco-tanapartholides isolated from Achillea falcata for inhibition of HaCaT cell growth.
European journal of medicinal chemistry.
2009 Sep; 44(9):3794-7. doi:
10.1016/j.ejmech.2009.04.029. [PMID: 19464086] - Bhahwal Ali Shah, Renu Chib, Pankaj Gupta, Vijay Kumar Sethi, Surrinder Koul, Samar Singh Andotra, Amit Nargotra, Sujata Sharma, Anjali Pandey, Sarang Bani, Basant Purnima, Subhash Chandra Taneja. Saponins as novel TNF-alpha inhibitors: isolation of saponins and a nor-pseudoguaianolide from Parthenium hysterophorus.
Organic & biomolecular chemistry.
2009 Aug; 7(16):3230-5. doi:
10.1039/b902041a. [PMID: 19641779] - Francisco A Macías, María D García-Díaz, Alejandro Pérez-de-Luque, Diego Rubiales, Juan C G Galindo. New chemical clues for broomrape-sunflower host-parasite interactions: synthesis of guaianestrigolactones.
Journal of agricultural and food chemistry.
2009 Jul; 57(13):5853-64. doi:
10.1021/jf900870j. [PMID: 19507857] - Maged Saad Abdel-Kader, Saleh Ibrahim Alqasoumi, Areej Mohammad Al-Taweel. Hepatoprotective constituents from Cleome droserifolia.
Chemical & pharmaceutical bulletin.
2009 Jun; 57(6):620-4. doi:
10.1248/cpb.57.620. [PMID: 19483347] - Abubaker A B Atrrog, Maja Natić, Tomislav Tosti, Dusanka Milojković-Opsenica, Iris Dordević, Vele Tesević, Milka Jadranin, Slobodan Milosavljević, Milan Lazić, Sinisa Radulović, Zivoslav Tesić. Lipophilicity of some guaianolides isolated from two endemic subspecies of Amphoricarpos neumayeri (Asteraceae) from Montenegro.
Biomedical chromatography : BMC.
2009 Mar; 23(3):250-6. doi:
10.1002/bmc.1091. [PMID: 18816478] - Y Choi, M K Lee, S Y Lim, S H Sung, Y C Kim. Inhibition of inducible NO synthase, cyclooxygenase-2 and interleukin-1beta by torilin is mediated by mitogen-activated protein kinases in microglial BV2 cells.
British journal of pharmacology.
2009 Mar; 156(6):933-40. doi:
10.1111/j.1476-5381.2009.00022.x. [PMID: 19298258] - Jiang Jiang Qin, Hui Zi Jin, Jian Jun Fu, Xiao Jia Hu, Yan Wang, Shi Kai Yan, Wei Dong Zhang. Japonicones A-D, bioactive dimeric sesquiterpenes from Inula japonica Thunb.
Bioorganic & medicinal chemistry letters.
2009 Feb; 19(3):710-3. doi:
10.1016/j.bmcl.2008.12.043. [PMID: 19117757] - Ji Young Choi, Minkyun Na, In Hyun Hwang, Seung Ho Lee, Eun Young Bae, Bo Yeon Kim, Jong Seog Ahn. Isolation of betulinic acid, its methyl ester and guaiane sesquiterpenoids with protein tyrosine phosphatase 1B inhibitory activity from the roots of Saussurea lappa C.B.Clarke.
Molecules (Basel, Switzerland).
2009 Jan; 14(1):266-72. doi:
10.3390/molecules14010266. [PMID: 19136914] - Ranjala Ratnayake, David Covell, Tanya T Ransom, Kirk R Gustafson, John A Beutler. Englerin A, a selective inhibitor of renal cancer cell growth, from Phyllanthus engleri.
Organic letters.
2009 Jan; 11(1):57-60. doi:
10.1021/ol802339w. [PMID: 19061394] - Ki Hun Park, Min Suk Yang, Moon Ki Park, Sang Chan Kim, Chae Ha Yang, Sook Jahr Park, Jong Rok Lee. A new cytotoxic guaianolide from Chrysanthemum boreale.
Fitoterapia.
2009 Jan; 80(1):54-6. doi:
10.1016/j.fitote.2008.09.013. [PMID: 18983901] - Yan Wang, Yun-Heng Shen, Hui-Zi Jin, Jian-Jun Fu, Xiao-Jia Hu, Jiang-Jiang Qin, Jian-Hua Liu, Ming Chen, Shi-Kai Yan, Wei-Dong Zhang. Ainsliatrimers A and B, the first two guaianolide trimers from Ainsliaea fulvioides.
Organic letters.
2008 Dec; 10(24):5517-20. doi:
10.1021/ol802249z. [PMID: 19007177] - Fei Wang, Zheng-Hong Xie, Yuan Gao, Yao Xu, Xue-Lian Cheng, Ji-Kai Liu. Sulfonated guaianolides from Saussurea lappa.
Chemical & pharmaceutical bulletin.
2008 Jun; 56(6):864-5. doi:
10.1248/cpb.56.864. [PMID: 18520098] - W-I Cho, J-B Choi, K Lee, M-S Chung, Y-R Pyun. Antimicrobial activity of torilin isolated from Torilis japonica fruit against Bacillus subtilis.
Journal of food science.
2008 Mar; 73(2):M37-46. doi:
10.1111/j.1750-3841.2007.00639.x. [PMID: 18298734] - Xue Gao, Wei-Dong Xie, Zhong-Jian Jia. Four new terpenoids from the roots of Ligularia narynensis.
Journal of Asian natural products research.
2008 Jan; 10(1-2):185-92. doi:
10.1080/10286020701394431. [PMID: 18253887] - Heng-Xing Liang, Fu-Kai Bao, Xiao-Ping Dong, Hua-Jie Zhu, Xiao-Jie Lu, Ming Shi, Qing Lu, Yong-Xian Cheng. Two new antibacterial sesquiterpenoids from Centipeda minima.
Chemistry & biodiversity.
2007 Dec; 4(12):2810-6. doi:
10.1002/cbdv.200790230. [PMID: 18081091] - Biswanath Das, V Saidi Reddy, M Krishnaiah, A V S Sharma, K Ravi Kumar, J Venkateswara Rao, V Sridhar. Acetylated pseudoguaianolides from Parthenium hysterophorus and their cytotoxic activity.
Phytochemistry.
2007 Aug; 68(15):2029-34. doi:
10.1016/j.phytochem.2007.05.002. [PMID: 17570445] - Young Choong Kim, Mi Kyeong Lee, Sang Hyun Sung, Seung Hyun Kim. Sesquiterpenes from Ulmus davidiana var. japonica with the inhibitory effects on lipopolysaccharide-induced nitric oxide production.
Fitoterapia.
2007 Apr; 78(3):196-9. doi:
10.1016/j.fitote.2006.11.013. [PMID: 17343992] - Yong Geun Kwak, Dae Keun Kim, Tian-Ze Ma, Sun-Ah Park, Hoon Park, Young Hoon Jung, Dong-Jin Yoo, Jae Soon Eun. Torilin from Torilis japonica (Houtt.) DC. blocks hKv1.5 channel current.
Archives of pharmacal research.
2006 Oct; 29(10):834-9. doi:
10.1007/bf02973902. [PMID: 17121176] - A Wesołowska, A Nikiforuk, K Michalska, W Kisiel, E Chojnacka-Wójcik. Analgesic and sedative activities of lactucin and some lactucin-like guaianolides in mice.
Journal of ethnopharmacology.
2006 Sep; 107(2):254-8. doi:
10.1016/j.jep.2006.03.003. [PMID: 16621374] - L Yang, J Dai, J-I Sakai, M Ando. Biotransformation of alpha- and 6beta-santonin by fungus and plant cell cultures.
Journal of Asian natural products research.
2006 Jun; 8(4):317-26. doi:
10.1080/10286020500035151. [PMID: 16864442] - Snezana Trifunović, Vlatka Vajs, Zorica Juranić, Zeljko Zizak, Vele Tesević, Slobodan Macura, Slobodan Milosavljević. Cytotoxic constituents of Achillea clavennae from Montenegro.
Phytochemistry.
2006 May; 67(9):887-93. doi:
10.1016/j.phytochem.2006.02.026. [PMID: 16616262] - Antoaneta Trendafilova, Milka Todorova, Bozhanka Mikhova, Antonina Vitkova, Helmut Duddeck. Sesquiterpene lactones from Achillea collina J. Becker ex Reichenb.
Phytochemistry.
2006 Apr; 67(8):764-70. doi:
10.1016/j.phytochem.2006.01.033. [PMID: 16530795] - Wenliang Chen, Qunfang Liu, Jian Wang, Jian Zou, Dahai Meng, Jianping Zuo, Xingzu Zhu, Weimin Zhao. New guaiane, megastigmane and eudesmane-type sesquiterpenoids and anti-inflammatory constituents from Youngia japonica.
Planta medica.
2006 Feb; 72(2):143-50. doi:
10.1055/s-2005-916182. [PMID: 16491450] - Sylvie Bercion, Marie-Anna Couppe de K Martin, Jean-Pierre Baltaze, Paul Bourgeois. A new alpha-methylene gamma-lactone sesquiterpene from Hedyosmum arborescens.
Fitoterapia.
2005 Dec; 76(7-8):620-4. doi:
10.1016/j.fitote.2005.06.006. [PMID: 16395780] - Olha Kos, Maja T Lindenmeyer, Aurelia Tubaro, Silvio Sosa, Irmgard Merfort. New sesquiterpene lactones from Arnica tincture prepared from fresh flowerheads of Arnica montana.
Planta medica.
2005 Nov; 71(11):1044-52. doi:
10.1055/s-2005-871284. [PMID: 16320207] - Gordana Stojanović, Niko Radulović, Toshihiro Hashimoto, Radosav Palić. In vitro antimicrobial activity of extracts of four Achillea species: the composition of Achillea clavennae L. (Asteraceae) extract.
Journal of ethnopharmacology.
2005 Oct; 101(1-3):185-90. doi:
10.1016/j.jep.2005.04.026. [PMID: 15978758] - Rasheeduzzaman Chowdhury, Rizwana Binte Rashid, Choudhury M Hasan, Mohammad A Rashid. Chemotaxonomic significance of guaiane sesquiterpenoids from Amoora rohituka.
Pakistan journal of pharmaceutical sciences.
2005 Apr; 18(2):63-4. doi:
". [PMID: 16431403] - P M Aksartov, A E Guliaev, S M Adekenov. [Features of leucomisin pharmacokinetics in the blood serum upon introduction by various methods].
Eksperimental'naia i klinicheskaia farmakologiia.
2005 Mar; 68(2):44-6. doi:
NULL. [PMID: 15934367] - Mitsuo Miyazawa, Atsushi Sugawara. Biotransformation of alpha-bulnesene using a plant pathogenic fungus, Glomerella cingulata as a biocatalyst.
Natural product research.
2005 Feb; 19(2):111-5. doi:
10.1080/14786410410001704697. [PMID: 15715253] - Sher Bahadar Khan, Azhar-ul-Haq, Shagufta Perveen, Nighat Afza, Abdul Malik, Sarfraz Ahmad Nawaz, Muhammad Raza Shah, Muhammad Iqbal Choudhary. Butyrylcholinesterase inhibitory guaianolides from Amberboa ramosa.
Archives of pharmacal research.
2005 Feb; 28(2):172-6. doi:
10.1007/bf02977710. [PMID: 15789746] - Li-Yan Wang, Tomoko Unehara, Susumu Kitanaka. Anti-inflammatory activity of new guaiane type sesquiterpene from Wikstroemia indica.
Chemical & pharmaceutical bulletin.
2005 Jan; 53(1):137-9. doi:
10.1248/cpb.53.137. [PMID: 15635251] - Jun Huo, Sheng-Ping Yang, Jian Ding, Jian-Min Yue. Cytotoxic sesquiterpene lactones from Eupatorium lindleyanum.
Journal of natural products.
2004 Sep; 67(9):1470-5. doi:
10.1021/np040023h. [PMID: 15387644] - Iris Djordjević, Vlatka Vajs, Vanja Bulatović, Nebojsa Menković, Vele Tesević, Slobodan Macura, Pedja Janaćković, Slobodan Milosavljević. Guaianolides from two subspecies of Amphoricarpos neumayeri from Montenegro.
Phytochemistry.
2004 Aug; 65(16):2337-45. doi:
10.1016/j.phytochem.2004.07.014. [PMID: 15381005] - Jordanka Staneva, Antoaneta Trendafilova-Savkova, Milka N Todorova, Ljuba Evstatieva, Antonina Vitkova, Jordanka Staneva, Antoaneta Trendafilova-Savkova, Milka N Todorova, Ljuba Evstatieva, Antonina Vitkova. Terpenoids from Anthemis austriaca Jacq.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2004 Mar; 59(3-4):161-5. doi:
10.1515/znc-2004-3-403. [PMID: 15241916] - Wanda Kisiel, Klaudia Michalska. Root constituents of Cichorium pumilum and rearrangements of some lactucin-like guaianolides.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2003 Nov; 58(11-12):789-92. doi:
10.1515/znc-2003-11-1206. [PMID: 14713151] - Yun-Sen Li, Ji-Jun Chen, Hui Zhou, Shi-De Luo, Hui-Ying Wang, Da-Yuan Zhu. Two new guaianolides and a new daucene derivative from Sinodielsia yunnanensis.
Planta medica.
2003 Oct; 69(10):962-4. doi:
10.1055/s-2003-45111. [PMID: 14648405]