Capilliposide B (BioDeep_00000262366)

   

Cytotoxicity


代谢物信息卡片


Capilliposide B

化学式: C58H96O24 (1176.6291216)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCC(=O)OC1CC(C)(C)CC2C13C(O)CC1(C)C2(CCC2(C)C4CCC(OC5COC(OC6OC(CO)C(O)C(O)C6OC6OCC(O)C(O)C6O)C(O)C5OC5OC(CO)C(O)C(O)C5O)C(C)(C)C4CCC21C)OC3O
InChI: InChI=1S/C58H96O24/c1-9-10-11-12-36(63)78-35-21-52(2,3)19-32-57-18-14-31-54(6)16-15-34(53(4,5)30(54)13-17-55(31,7)56(57,8)20-33(62)58(32,35)51(72)82-57)79-49-45(81-48-44(71)41(68)38(65)27(22-59)75-48)40(67)29(25-74-49)77-50-46(42(69)39(66)28(23-60)76-50)80-47-43(70)37(64)26(61)24-73-47/h26-35,37-51,59-62,64-72H,9-25H2,1-8H3/t26-,27-,28-,29+,30+,31-,32+,33-,34+,35+,37+,38-,39-,40+,41+,42+,43-,44-,45-,46-,47+,48+,49+,50+,51-,54+,55-,56+,57+,58-/m1/s1

描述信息

A triterpenoid saponin that consists of anagalligenin A substituted by a caproyl group at position 22 and a beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranosyl-(1->4)-[beta-D-glucopyranosyl-(1->2)]-alpha-L-arabinopyranosyl moiety at position 3 via a glycosidic linkage. It is isolated from the whole plants of Lysimachia capillipes and has been shown to exhibit potent cytotoxicity against human A-2780 cells.

同义名列表

1 个代谢物同义名

Capilliposide B



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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文献列表

  • Zhongzhe Cheng, Xing Zhou, Bingying Hu, Wenyi Li, Guiying Chen, Yang Zhang, Jingkui Tian, Lin Zhang, Ming Li, Hongliang Jiang. Tissue distribution of capilliposide B, capilliposide C and their bioactive metabolite in mice using liquid -tandem mass spectrometry. Biomedical chromatography : BMC. 2017 Jun; 31(6):. doi: 10.1002/bmc.3895. [PMID: 27859436]
  • Zhongzhe Cheng, Xing Zhou, Wenyi Li, Bingying Hu, Yang Zhang, Yong Xu, Lin Zhang, Hongliang Jiang. Optimization of solid-phase extraction and liquid chromatography-tandem mass spectrometry for simultaneous determination of capilliposide B and its active metabolite in rat urine and feces: Overcoming nonspecific binding. Journal of pharmaceutical and biomedical analysis. 2016 Nov; 131(?):6-12. doi: 10.1016/j.jpba.2016.08.003. [PMID: 27521984]
  • Zhongzhe Cheng, Lin Zhang, Yang Zhang, Guiying Chen, Hongliang Jiang. Simultaneous determination of capilliposide B and capilliposide C in rat plasma by LC-MS/MS and its application to a PK study. Bioanalysis. 2014 Apr; 6(7):935-45. doi: 10.4155/bio.13.328. [PMID: 24313264]
  • Andria Agusta, Kazuyoshi Ohashi, Hirotaka Shibuya. Bisanthraquinone metabolites produced by the endophytic fungus Diaporthe sp. Chemical & pharmaceutical bulletin. 2006 Apr; 54(4):579-82. doi: 10.1248/cpb.54.579. [PMID: 16595971]