Boeravinone B (BioDeep_00000257791)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


6a,12a-Dehydro-6,9,11-trihydroxy-10-methylrotenone

化学式: C17H12O6 (312.0634)
中文名称: 黄细心酮 B
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c1(c(c(c2c(c1)oc1c(c2=O)c2ccccc2O[C@H]1O)O)C)O
InChI: InChI=1S/C17H12O6/c1-7-9(18)6-11-13(14(7)19)15(20)12-8-4-2-3-5-10(8)23-17(21)16(12)22-11/h2-6,17-19,21H,1H3/t17-/m1/s1

描述信息

同义名列表

2 个代谢物同义名

6a,12a-Dehydro-6,9,11-trihydroxy-10-methylrotenone; Boeravinone B



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

10 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Xianyu Piao, Jung-Woo Kim, Moonjung Hyun, Zhao Wang, Suk-Gyun Park, In A Cho, Je-Hwang Ryu, Bin-Na Lee, Ju Han Song, Jeong-Tae Koh. Boeravinone B, a natural rotenoid, inhibits osteoclast differentiation through modulating NF-κB, MAPK and PI3K/Akt signaling pathways. BMB reports. 2023 Aug; ?(?):. doi: . [PMID: 37574806]
  • Zuhong Wang, Sha Xiao, Jun Huang, Sutao Liu, Mei Xue, Fang Lu. Chemoprotective Effect of Boeravinone B against DMBA/Croton Oil Induced Skin Cancer via Reduction of Inflammation. Journal of oleo science. 2021; 70(7):955-964. doi: 10.5650/jos.ess21055. [PMID: 34193671]
  • Shaojie Yuan, Tong Zhang. Boeravinone B Protects Brain against Cerebral Ichemia Reperfusion Injury in Rats: Possible Role of Anti-inflammatory and Antioxidant. Journal of oleo science. 2021; 70(7):927-936. doi: 10.5650/jos.ess21037. [PMID: 34193669]
  • Eun-Ju Yang, Taeho Lee, Kyung-Sik Song. β-Secretase inhibition by C-methylisoflavones from Abronia nana. Natural product research. 2019 Jun; 33(12):1705-1712. doi: 10.1080/14786419.2018.1431637. [PMID: 29382223]
  • Ruby Gupta, Pallavi Pandey, Sailendra Singh, Dhananjay Kumar Singh, Archana Saxena, Suaib Luqman, Dnyaneshwar U Bawankule, Suchitra Banerjee. Advances in Boerhaavia diffusa hairy root technology: a valuable pursuit for identifying strain sensitivity and up-scaling factors to refine metabolite yield and bioactivity potentials. Protoplasma. 2016 Jul; 253(4):1145-58. doi: 10.1007/s00709-015-0875-5. [PMID: 26315820]
  • Khemraj Bairwa, Sanjay Madhukar Jachak. Anti-inflammatory potential of a lipid-based formulation of a rotenoid-rich fraction prepared from Boerhavia diffusa. Pharmaceutical biology. 2015 Aug; 53(8):1231-8. doi: 10.3109/13880209.2014.971382. [PMID: 25864706]
  • Khemraj Bairwa, Ishwari N Singh, Somendu K Roy, Jagdeep Grover, Amit Srivastava, Sanjay M Jachak. Rotenoids from Boerhaavia diffusa as potential anti-inflammatory agents. Journal of natural products. 2013 Aug; 76(8):1393-8. doi: 10.1021/np300899w. [PMID: 23914900]
  • S G Bhope, P S Gaikwad, V V Kuber, M J Patil. RP-HPLC method for the simultaneous quantitation of boeravinone E and boeravinone B in Boerhaavia diffusa extract and its formulation. Natural product research. 2013; 27(6):588-91. doi: 10.1080/14786419.2012.676550. [PMID: 22480291]
  • Shrinivas G Bhope, Vivek K Ghosh, Vinod V Kuber, Manohar J Patil. Rapid microwave-assisted extraction and HPTLC-photodensitometric method for the quality assessment of Boerhaavia diffusa L. Journal of AOAC International. 2011 May; 94(3):795-802. doi: 10.1093/jaoac/94.3.795. [PMID: 21797007]
  • Abdelhakim Ahmed-Belkacem, Sira Macalou, Francesca Borrelli, Raffaele Capasso, Ernesto Fattorusso, Orazio Taglialatela-Scafati, Attilio Di Pietro. Nonprenylated rotenoids, a new class of potent breast cancer resistance protein inhibitors. Journal of medicinal chemistry. 2007 Apr; 50(8):1933-8. doi: 10.1021/jm061450q. [PMID: 17341062]