4-Oxononanal (BioDeep_00000025508)

   

human metabolite natural product


代谢物信息卡片


4-Oxononan-1-al

化学式: C9H16O2 (156.1150236)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCC(=O)CCC=O
InChI: InChI=1S/C9H16O2/c1-2-3-4-6-9(11)7-5-8-10/h8H,2-7H2,1H3

描述信息

Present in used frying oils and water melon aroma. Tentatively identified in roast chicken fat. 4-Oxononanal is found in fats and oils, animal foods, and fruits.
4-Oxononanal is found in animal foods. 4-Oxononanal is present in used frying oils and water melon aroma. Tentatively identified in roast chicken fa

同义名列表

2 个代谢物同义名

4-Oxononan-1-al; 4-Oxononanal



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

12 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Fabio Di Domenico, Rukhsana Sultana, Andrew Ferree, Katelyn Smith, Eugenio Barone, Marzia Perluigi, Raffaella Coccia, William Pierce, Jian Cai, Cesare Mancuso, Rachel Squillace, Manfred Wiengele, Isabella Dalle-Donne, Benjamin Wolozin, D Allan Butterfield. Redox proteomics analyses of the influence of co-expression of wild-type or mutated LRRK2 and Tau on C. elegans protein expression and oxidative modification: relevance to Parkinson disease. Antioxidants & redox signaling. 2012 Dec; 17(11):1490-506. doi: 10.1089/ars.2011.4312. [PMID: 22315971]
  • Darío Méndez, María L Hernáez, Ali N Kamali, Amalia Diez, Antonio Puyet, José M Bautista. Differential carbonylation of cytoskeletal proteins in blood group O erythrocytes: potential role in protection against severe malaria. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 2012 Dec; 12(8):1780-7. doi: 10.1016/j.meegid.2012.06.013. [PMID: 22771625]
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  • Marzia Perluigi, Raffaella Coccia, D Allan Butterfield. 4-Hydroxy-2-nonenal, a reactive product of lipid peroxidation, and neurodegenerative diseases: a toxic combination illuminated by redox proteomics studies. Antioxidants & redox signaling. 2012 Dec; 17(11):1590-609. doi: 10.1089/ars.2011.4406. [PMID: 22114878]
  • Cagri Bodur, Ozgur Kutuk, Tugsan Tezil, Huveyda Basaga. Inactivation of Bcl-2 through IκB kinase (IKK)-dependent phosphorylation mediates apoptosis upon exposure to 4-hydroxynonenal (HNE). Journal of cellular physiology. 2012 Nov; 227(11):3556-65. doi: 10.1002/jcp.24057. [PMID: 22262057]
  • Gabriella Testa, Paola Gamba, Federica Di Scipio, Andrea Elio Sprio, Paolina Salamone, Simona Gargiulo, Barbara Sottero, Fiorella Biasi, Giovanni Nicolao Berta, Giuseppe Poli, Gabriella Leonarduzzi. Potentiation of amyloid-β peptide neurotoxicity in human dental-pulp neuron-like cells by the membrane lipid peroxidation product 4-hydroxynonenal. Free radical biology & medicine. 2012 Nov; 53(9):1708-17. doi: 10.1016/j.freeradbiomed.2012.08.581. [PMID: 22981873]
  • Tae Sik Jung, Soo Kyoung Kim, Hyun Joo Shin, Byeong Tak Jeon, Jong Ryeal Hahm, Gu Seob Roh. α-lipoic acid prevents non-alcoholic fatty liver disease in OLETF rats. Liver international : official journal of the International Association for the Study of the Liver. 2012 Nov; 32(10):1565-73. doi: 10.1111/j.1478-3231.2012.02857.x. [PMID: 22863080]
  • Xiaobing Dou, Songtao Li, Zhigang Wang, Dongfang Gu, Chen Shen, Tong Yao, Zhenyuan Song. Inhibition of NF-κB activation by 4-hydroxynonenal contributes to liver injury in a mouse model of alcoholic liver disease. The American journal of pathology. 2012 Nov; 181(5):1702-10. doi: 10.1016/j.ajpath.2012.08.004. [PMID: 22982442]
  • D Fu, M Wu, J Zhang, M Du, S Yang, S M Hammad, K Wilson, J Chen, T J Lyons. Mechanisms of modified LDL-induced pericyte loss and retinal injury in diabetic retinopathy. Diabetologia. 2012 Nov; 55(11):3128-40. doi: 10.1007/s00125-012-2692-0. [PMID: 22935961]
  • Farzana Khatoon, Moinuddin, Khursheed Alam, Asif Ali. Physicochemical and immunological studies on 4-hydroxynonenal modified HSA: implications of protein damage by lipid peroxidation products in the etiopathogenesis of SLE. Human immunology. 2012 Nov; 73(11):1132-9. doi: 10.1016/j.humimm.2012.08.011. [PMID: 22917540]
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  • Chabetty Y Vargas-Olvera, Dolores Javier Sánchez-González, José D Solano, Francisco A Aguilar-Alonso, Fernando Montalvo-Muñoz, Claudia María Martínez-Martínez, Omar N Medina-Campos, María Elena Ibarra-Rubio. Characterization of N-diethylnitrosamine-initiated and ferric nitrilotriacetate-promoted renal cell carcinoma experimental model and effect of a tamarind seed extract against acute nephrotoxicity and carcinogenesis. Molecular and cellular biochemistry. 2012 Oct; 369(1-2):105-17. doi: 10.1007/s11010-012-1373-0. [PMID: 22761015]
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  • R John Aitken, Sara Whiting, Geoffry N De Iuliis, Samantha McClymont, Lisa A Mitchell, Mark A Baker. Electrophilic aldehydes generated by sperm metabolism activate mitochondrial reactive oxygen species generation and apoptosis by targeting succinate dehydrogenase. The Journal of biological chemistry. 2012 Sep; 287(39):33048-60. doi: 10.1074/jbc.m112.366690. [PMID: 22851170]
  • Kirill Tsirulnikov, Natalia Abuladze, Anatol Bragin, Kym Faull, Duilio Cascio, Robert Damoiseaux, Matthew J Schibler, Alexander Pushkin. Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal. Toxicology and applied pharmacology. 2012 Sep; 263(3):303-14. doi: 10.1016/j.taap.2012.07.002. [PMID: 22819785]
  • Lilu Guo, Zhongyi Chen, Venkataraman Amarnath, Sean S Davies. Identification of novel bioactive aldehyde-modified phosphatidylethanolamines formed by lipid peroxidation. Free radical biology & medicine. 2012 Sep; 53(6):1226-38. doi: 10.1016/j.freeradbiomed.2012.07.077. [PMID: 22898174]
  • Hiroko Hoshi, Wu Hao, Yoshinari Fujita, Atsushi Funayama, Yoshiteru Miyauchi, Kazuaki Hashimoto, Kana Miyamoto, Ryotaro Iwasaki, Yuiko Sato, Tami Kobayashi, Hiroya Miyamoto, Shigeyuki Yoshida, Tomoaki Mori, Hiroya Kanagawa, Eri Katsuyama, Atsuhiro Fujie, Kyoko Kitagawa, Keiichi I Nakayama, Toshihiro Kawamoto, Motoaki Sano, Keiichi Fukuda, Ikuroh Ohsawa, Shigeo Ohta, Hideo Morioka, Morio Matsumoto, Kazuhiro Chiba, Yoshiaki Toyama, Takeshi Miyamoto. Aldehyde-stress resulting from Aldh2 mutation promotes osteoporosis due to impaired osteoblastogenesis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2012 Sep; 27(9):2015-23. doi: 10.1002/jbmr.1634. [PMID: 22508505]
  • Anu Kauppinen, Henri Niskanen, Tiina Suuronen, Kati Kinnunen, Antero Salminen, Kai Kaarniranta. Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells--implications for age-related macular degeneration (AMD). Immunology letters. 2012 Sep; 147(1-2):29-33. doi: 10.1016/j.imlet.2012.05.005. [PMID: 22698681]
  • Tolgahan Kocadağlı, Neslihan Göncüoğlu, Aytül Hamzalıoğlu, Vural Gökmen. In depth study of acrylamide formation in coffee during roasting: role of sucrose decomposition and lipid oxidation. Food & function. 2012 Sep; 3(9):970-5. doi: 10.1039/c2fo30038a. [PMID: 22796869]
  • Paul W Buehler, Jin Hyen Baek, Christina Lisk, Ian Connor, Tim Sullivan, Douglas Kominsky, Susan Majka, Kurt R Stenmark, Eva Nozik-Grayck, Joe Bonaventura, David C Irwin. Free hemoglobin induction of pulmonary vascular disease: evidence for an inflammatory mechanism. American journal of physiology. Lung cellular and molecular physiology. 2012 Aug; 303(4):L312-26. doi: 10.1152/ajplung.00074.2012. [PMID: 22728465]
  • A Piechota-Polanczyk, A Goraca, S Demyanets, M Mittlboeck, C Domenig, C Neumayer, J Wojta, J Nanobachvili, I Huk, M Klinger. Simvastatin decreases free radicals formation in the human abdominal aortic aneurysm wall via NF-κB. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 2012 Aug; 44(2):133-7. doi: 10.1016/j.ejvs.2012.04.020. [PMID: 22694979]
  • Morana Jaganjac, Tamara Cacev, Ana Cipak, Sanja Kapitanović, Koraljka Gall Troselj, Neven Zarković. Even stressed cells are individuals: second messengers of free radicals in pathophysiology of cancer. Croatian medical journal. 2012 Aug; 53(4):304-9. doi: 10.3325/cmj.2012.53.304. [PMID: 22911521]
  • A Djamali, S Reese, O Hafez, A Vidyasagar, L Jacobson, W Swain, C Kolehmainen, L Huang, N A Wilson, J R Torrealba. Nox2 is a mediator of chronic CsA nephrotoxicity. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2012 Aug; 12(8):1997-2007. doi: 10.1111/j.1600-6143.2012.04081.x. [PMID: 22568654]
  • Langston T Holly, Donald Blaskiewicz, Aiguo Wu, Cameron Feng, Zhe Ying, Fernando Gomez-Pinilla. Dietary therapy to promote neuroprotection in chronic spinal cord injury. Journal of neurosurgery. Spine. 2012 Aug; 17(2):134-40. doi: 10.3171/2012.5.spine1216. [PMID: 22735048]
  • Khalil Miloudi, Blandine Comte, Thérèse Rouleau, Alain Montoudis, Emile Levy, Jean-Claude Lavoie. The mode of administration of total parenteral nutrition and nature of lipid content influence the generation of peroxides and aldehydes. Clinical nutrition (Edinburgh, Scotland). 2012 Aug; 31(4):526-34. doi: 10.1016/j.clnu.2011.12.012. [PMID: 22230256]
  • Serdar Dogan, Gulsum Ozlem Elpek, Esma Kirimlioglu Konuk, Nejdet Demir, Mutay Aslan. Measurement of intracellular biomolecular oxidation in liver ischemia-reperfusion injury via immuno-spin trapping. Free radical biology & medicine. 2012 Aug; 53(3):406-14. doi: 10.1016/j.freeradbiomed.2012.05.028. [PMID: 22634144]
  • Tatsuki Itoh, Motohiro Imano, Shozo Nishida, Masahiro Tsubaki, Nobuyuki Mizuguchi, Shigeo Hashimoto, Akihiko Ito, Takao Satou. (-)-Epigallocatechin-3-gallate increases the number of neural stem cells around the damaged area after rat traumatic brain injury. Journal of neural transmission (Vienna, Austria : 1996). 2012 Aug; 119(8):877-90. doi: 10.1007/s00702-011-0764-9. [PMID: 22212485]
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