adhyperforin (BioDeep_00000252306)

 

Secondary id: BioDeep_00001885738

PANOMIX_OTCML-2023


代谢物信息卡片


4-Hydroxy-8-methyl-1-(2-methylbutanoyl)-3,5,7-tris(3-methylbut-2-enyl)-8-(4-methylpent-3-enyl)bicyclo[3.3.1]non-3-ene-2,9-dione

化学式: C36H54O4 (550.4021884)
中文名称:
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 11.11%

分子结构信息

SMILES: CCC(C)C(=O)C12C(=O)C(=C(C(C1=O)(CC(C2(C)CCC=C(C)C)CC=C(C)C)CC=C(C)C)O)CC=C(C)C
InChI: InChI=1S/C36H54O4/c1-12-27(10)30(37)36-32(39)29(18-16-25(6)7)31(38)35(33(36)40,21-19-26(8)9)22-28(17-15-24(4)5)34(36,11)20-13-14-23(2)3/h14-16,19,27-28,38H,12-13,17-18,20-22H2,1-11H3

描述信息

同义名列表

2 个代谢物同义名

4-Hydroxy-8-methyl-1-(2-methylbutanoyl)-3,5,7-tris(3-methylbut-2-enyl)-8-(4-methylpent-3-enyl)bicyclo[3.3.1]non-3-ene-2,9-dione; adhyperforin



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Tomás Herraiz, Hugo Guillén. Monoamine Oxidase-A Inhibition and Associated Antioxidant Activity in Plant Extracts with Potential Antidepressant Actions. BioMed research international. 2018; 2018(?):4810394. doi: 10.1155/2018/4810394. [PMID: 29568754]
  • Wan Gao, Wei-Zhen Hou, Jun Zhao, Fang Xu, Li Li, Fang Xu, Hua Sun, Jian-Guo Xing, Ying Peng, Xiao-Liang Wang, Teng-Fei Ji, Zheng-Yi Gu. Polycyclic Polyprenylated Acylphloroglucinol Congeners from Hypericum scabrum. Journal of natural products. 2016 06; 79(6):1538-47. doi: 10.1021/acs.jnatprod.5b01063. [PMID: 27280968]
  • Andrea Kucharíková, Katarína Kimáková, Christian Janfelt, Eva Čellárová. Interspecific variation in localization of hypericins and phloroglucinols in the genus Hypericum as revealed by desorption electrospray ionization mass spectrometry imaging. Physiologia plantarum. 2016 May; 157(1):2-12. doi: 10.1111/ppl.12422. [PMID: 26822391]
  • Xing-Wei Yang, Ming-Ming Li, Xia Liu, Daneel Ferreira, Yuanqing Ding, Jing-Jing Zhang, Yang Liao, Hong-Bo Qin, Gang Xu. Polycyclic Polyprenylated Acylphloroglucinol Congeners Possessing Diverse Structures from Hypericum henryi. Journal of natural products. 2015 Apr; 78(4):885-95. doi: 10.1021/acs.jnatprod.5b00057. [PMID: 25871261]
  • Jingwei Tian, Fangxi Zhang, Jucan Cheng, Shuren Guo, Pinglan Liu, Hongbo Wang. Antidepressant-like activity of adhyperforin, a novel constituent of Hypericum perforatum L. Scientific reports. 2014 Jul; 4(?):5632. doi: 10.1038/srep05632. [PMID: 25005489]
  • Silvio Sosa, Roberto Pace, Anna Bornancin, Paolo Morazzoni, Antonella Riva, Aurelia Tubaro, Roberto Della Loggia. Topical anti-inflammatory activity of extracts and compounds from Hypericum perforatum L. The Journal of pharmacy and pharmacology. 2007 May; 59(5):703-9. doi: 10.1211/jpp.59.5.0011. [PMID: 17524236]
  • Lekha Sleno, Rambod Daneshfar, Gunter P Eckert, Walter E Müller, Dietrich A Volmer. Mass spectral characterization of phloroglucinol derivatives hyperforin and adhyperforin. Rapid communications in mass spectrometry : RCM. 2006; 20(18):2641-8. doi: 10.1002/rcm.2650. [PMID: 16912989]
  • Ari Tolonen, Anja Hohtola, Jorma Jalonen. Fast high-performance liquid chromatographic analysis of naphthodianthrones and phloroglucinols from Hypericum perforatum extracts. Phytochemical analysis : PCA. 2003 Sep; 14(5):306-9. doi: 10.1002/pca.720. [PMID: 14516003]
  • A Poutaraud, A Lobstein, P Girardin, B Weniger. Improved procedure for the quality control of Hypericum perforatum L. Phytochemical analysis : PCA. 2001 Nov; 12(6):355-62. doi: 10.1002/pca.601. [PMID: 11793812]
  • M Wonnemann, A Singer, B Siebert, W E Müller. Evaluation of synaptosomal uptake inhibition of most relevant constituents of St. John's wort. Pharmacopsychiatry. 2001 Jul; 34 Suppl 1(?):S148-51. doi: 10.1055/s-2001-15465. [PMID: 11518066]
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