Ochnaflavone (BioDeep_00000250923)

   

natural product


代谢物信息卡片


4H-1-Benzopyran-4-one, 2-(4-(5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenoxy)phenyl)-5,7-dihydroxy-

化学式: C30H18O10 (538.0899928)
中文名称: 似梨木双黄酮-7-O-Β-D-吡喃葡萄糖苷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)OC4=C(C=CC(=C4)C5=CC(=O)C6=C(C=C(C=C6O5)O)O)O
InChI: InChI=1S/C30H18O10/c31-16-8-20(34)29-22(36)12-24(39-27(29)10-16)14-1-4-18(5-2-14)38-26-7-15(3-6-19(26)33)25-13-23(37)30-21(35)9-17(32)11-28(30)40-25/h1-13,31-35H

描述信息

A biflavonoid with an ether linkage between the B-rings of the apigenin and luteolin subunits. It has been isolated from several members of the Ochnaceae plant family.

同义名列表

7 个代谢物同义名

Ochnaflavone; 4H-1-Benzopyran-4-one, 2-(4-(5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenoxy)phenyl)-5,7-dihydroxy-; 2-[3-[4-(5,7-dihydroxy-4-oxo-chromen-2-yl)phenoxy]-4-hydroxy-phenyl]-5,7-dihydroxy-chromen-4-one; 2-[3-[4-(5,7-dihydroxy-4-oxo-2-chromenyl)phenoxy]-4-hydroxyphenyl]-5,7-dihydroxy-4-chromenone; 2-[3-[4-(5,7-dihydroxy-4-oxochromen-2-yl)phenoxy]-4-hydroxyphenyl]-5,7-dihydroxychromen-4-one; 2-[3-[4-(5,7-dihydroxy-4-keto-chromen-2-yl)phenoxy]-4-hydroxy-phenyl]-5,7-dihydroxy-chromone; 50276-96-5



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

14 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yang Xie, Xi Zhou, Jing Li, Xiao-Chang Yao, Wan-Li Liu, Ping-Sheng Xu, Gui-Shan Tan. Cytotoxic effects of the biflavonoids isolated from Selaginella trichoclada on MCF-7 cells and its potential mechanism. Bioorganic & medicinal chemistry letters. 2022 01; 56(?):128486. doi: 10.1016/j.bmcl.2021.128486. [PMID: 34875389]
  • Eric Robert Tiam, Dominique Serge Ngono Bikobo, Auguste Abouem A Zintchem, Norbert Mbabi Nyemeck, Esther Del Florence Moni Ndedi, Patrick Hervé Betote Diboué, Maximilienne Ascension Nyegue, Alex de Théodore Atchadé, Dieudonné Emmanuel Pegnyemb, Christian G Bochet, Ulrich Koert. Secondary metabolites from Triclisia gilletii (De Wild) Staner (Menispermaceae) with antimycobacterial activity against Mycobacterium tuberculosis. Natural product research. 2019 Mar; 33(5):642-650. doi: 10.1080/14786419.2017.1402324. [PMID: 29144174]
  • Gaétan Bayiha Ba Njock, Raphaël Grougnet, Antonia Efstathiou, Despina Smirlis, Grégory Genta-Jouve, Sylvie Michel, Joséphine Ngo Mbing, Marina Kritsanida. A Nitrile Glucoside and Biflavones from the Leaves of Campylospermum excavatum (Ochnaceae). Chemistry & biodiversity. 2017 Nov; 14(11):. doi: 10.1002/cbdv.201700241. [PMID: 28695668]
  • Abdullahi M Ismail, Aliyu M Musa, Tajuddeen Nasir, Mohammed G Magaji, Yusuf A Jega, Iliya Ibrahim. Anti-proliferative study and isolation of Ochnaflavone from the ethyl acetate-soluble fraction of Ochna kibbiensis Hutch & Dalziel. Natural product research. 2017 Sep; 31(18):2149-2152. doi: 10.1080/14786419.2016.1274892. [PMID: 28032512]
  • Tshepiso J Makhafola, Babatunde B Samuel, Esameldin E Elgorashi, Jacobus N Eloff. Ochnaflavone and ochnaflavone 7-O-methyl ether two antibacterial biflavonoids from Ochna pretoriensis (Ochnaceae). Natural product communications. 2012 Dec; 7(12):1601-4. doi: NULL. [PMID: 23413563]
  • Jue-Hee Lee. Involvement of T-cell immunoregulation by ochnaflavone in therapeutic effect on fungal arthritis due to Candida albicans. Archives of pharmacal research. 2011 Jul; 34(7):1209-17. doi: 10.1007/s12272-011-0720-0. [PMID: 21811929]
  • Tae Chul Moon, Hwa Shin Hwang, Zhejiu Quan, Kun Ho Son, Cheorl-Ho Kim, Hyun Pyo Kim, Sam Sik Kang, Jong Keun Son, Hyeun Wook Chang. Ochnaflavone, naturally occurring biflavonoid, inhibits phospholipase A2 dependent phosphatidylethanolamine degradation in a CCl4-induced rat liver microsome. Biological & pharmaceutical bulletin. 2006 Dec; 29(12):2359-61. doi: 10.1248/bpb.29.2359. [PMID: 17142963]
  • Seok-Jong Suh, Un-Ho Jin, Sung-Hoon Kim, Hyeun-Wook Chang, Jong-Keun Son, Seung Ho Lee, Kun-Ho Son, Cheorl-Ho Kim. Ochnaflavone inhibits TNF-alpha-induced human VSMC proliferation via regulation of cell cycle, ERK1/2, and MMP-9. Journal of cellular biochemistry. 2006 Dec; 99(5):1298-307. doi: 10.1002/jcb.20912. [PMID: 16795041]