Thalicmidine (BioDeep_00000249126)

代谢物信息卡片

2,9,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1-ol

化学式: C20H23NO4 (341.16269980000004)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c12c(C[C@H]3c4c1c(c(cc4CCN3C)OC)O)cc(c(c2)OC)OC
InChI: InChI=1S/C20H23NO4/c1-21-6-5-11-8-17(25-4)20(22)19-13-10-16(24-3)15(23-2)9-12(13)7-14(21)18(11)19/h8-10,14,22H,5-7H2,1-4H3

描述信息

同义名列表

5 个代谢物同义名

2,9,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1-ol; (S)-O-Methylisoboldine; (+)-Thaliporphine; Thaliporphine; Thalicmidine

数据库引用编号

4 个数据库交叉引用编号

PubChem: 100020
KNApSAcK: C00027238
CAS: 5083-88-5
PMhub: MS000135780

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

15 个相关的物种来源信息

1433312 - Berberis heteropoda:
1112794 - Berberis integerrima:
1439896 - Berberis nummularia:
2602253 - Berberis oblonga:
559508 - Berberis repens: 10.1021/NP50018A011
258209 - Berberis vulgaris: 10.1007/BF01165220
581246 - Corydalis cava: 10.1055/S-2007-969652
2072396 - Glaucium arabicum:
1533087 - Glaucium corniculatum: 10.1016/0031-9422(88)84134-7
1353837 - Glaucium fimbrilligerum:
56853 - Glaucium flavum:
395328 - Thalictrum alpinum: 10.1016/0031-9422(95)00959-0
1084669 - Thalictrum fendleri: 10.2307/4117899
1084677 - Thalictrum ichangense:
476039 - Thalictrum minus:

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

A S Lee, W P Chen, Y L Kuo, Y J Ho, S S Lee, M J Su. Thaliporphine preserves cardiac function of endotoxemic rabbits by both directly and indirectly attenuating NFκB signaling pathway. PloS one. 2012; 7(6):e39174. doi: 10.1371/journal.pone.0039174. [PMID: 22761733]
Tzong-Cherng Chi, Shoei-Sheng Lee, Ming-Jai Su. Antihyperglycemic effect of aporphines and their derivatives in normal and diabetic rats. Planta medica. 2006 Oct; 72(13):1175-80. doi: 10.1055/s-2006-947199. [PMID: 16924583]
Wei-Luen Chang, Shoei-Sheng Lee, Ming-Jai Su. Attenuation of post-ischemia reperfusion injury by thaliporphine and morphine in rat hearts. Journal of biomedical science. 2005; 12(4):611-9. doi: 10.1007/s11373-005-7401-2. [PMID: 16132108]
Chin-Wei Chiao, Shoei-Sheng Lee, Chin-Chen Wu, Ming-Jai Su. Thaliporphine increases survival rate and attenuates multiple organ injury in LPS-induced endotoxaemia. Naunyn-Schmiedeberg's archives of pharmacology. 2005 Jan; 371(1):34-43. doi: 10.1007/s00210-004-1014-6. [PMID: 15654598]
S M Yu. Thaliporphine selectively inhibits expression of the inducible, but not the constitutive, nitric oxide synthase. The Biochemical journal. 1994 Oct; 303 ( Pt 1)(?):289-94. doi: 10.1042/bj3030289. [PMID: 7524482]
S M Yu, S S Lee, H Chou, C M Teng. Contractile effects caused by thaliporphine in the guinea-pig ileum. European journal of pharmacology. 1993 Mar; 234(1):121-3. doi: 10.1016/0014-2999(93)90715-t. [PMID: 8472755]
C M Teng, S M Yu, S S Lee, F N Ko, M J Su, T F Huang. Vasoconstricting effect in rat aorta caused by thaliporphine isolated from the plant Neolitsea konishii K. European journal of pharmacology. 1993 Mar; 233(1):7-12. doi: 10.1016/0014-2999(93)90342-f. [PMID: 8386090]