1-Hydroxy-2,3,5-trimethoxyxanthone (BioDeep_00000245575)

   


代谢物信息卡片


1-Hydroxy-2,3,5-trimethoxyxanthone

化学式: C16H14O6 (302.0790344)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c12c(oc3c(c1=O)c(c(c(c3)OC)OC)O)c(ccc2)OC
InChI: InChI=1S/C16H14O6/c1-19-9-6-4-5-8-13(17)12-10(22-15(8)9)7-11(20-2)16(21-3)14(12)18/h4-7,18H,1-3H3

描述信息

同义名列表

1 个代谢物同义名

1-Hydroxy-2,3,5-trimethoxyxanthone



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ru Feng, Xuelin Zhou, Xiang-Shan Tan, Penelope M Y Or, Tao Hu, Jie Fu, Jing-Yi Ma, Min Huang, Chi-Yu He, Jian-Gong Shi, Chun-Tao Che, John H K Yeung, Yan Wang. In vitro identification of cytochrome P450 isoforms responsible for the metabolism of 1-hydroxyl-2,3,5-trimethoxy-xanthone purified from Halenia elliptica D. Don. Chemico-biological interactions. 2014 Mar; 210(?):12-9. doi: 10.1016/j.cbi.2013.12.008. [PMID: 24380714]
  • Ru Feng, Xuelin Zhou, Penelope M Y Or, Jing-Yi Ma, Xiang-Shan Tan, Jie Fu, Chao Ma, Jian-Gong Shi, Chun-Tao Che, Yan Wang, John H K Yeung. Enzyme kinetic and molecular docking studies on the metabolic interactions of 1-hydroxy-2,3,5-trimethoxy-xanthone, isolated from Halenia elliptica D. Don, with model probe substrates of human cytochrome P450 enzymes. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2012 Sep; 19(12):1125-33. doi: 10.1016/j.phymed.2012.06.009. [PMID: 22819301]
  • Ru Feng, Yi-Ying Zhang, Xi Chen, Yan Wang, Jian-Gong Shi, Chun-Tao Che, John H K Yeung, Jing-Yi Ma, Xiang-Shan Tan, Chen Yang, Yu-Lin Deng, Yu-Kui Zhang. In vitro study on metabolite profiles of bioactive xanthones isolated from Halenia elliptica D. Don by high performance liquid chromatography coupled to ion trap time-of-flight mass spectrometry. Journal of pharmaceutical and biomedical analysis. 2012 Mar; 62(?):228-34. doi: 10.1016/j.jpba.2012.01.014. [PMID: 22310554]
  • Hongling Wang, Hao Chen, Chang'an Geng, Xuemei Zhang, Yunbao Ma, Zhiyong Jiang, Jijun Chen. [Chemical constituents of Halenia elliptica]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2011 Jun; 36(11):1454-7. doi: . [PMID: 22779176]
  • Rui Gu, Guoyue Zhong, Weizao Luo, Yi Zhang, Changhua Wang, Xiang Liu, Jifeng Zhao, Huarong Zhou. [Determination of xanthones in Tibetan herb Jiadiranguo (Herba Haleniae)]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2010 Nov; 35(21):2866-70. doi: ". [PMID: 21322948]
  • Yan Wang, Jian-Gong Shi, Mu-Zou Wang, Chun-Tao Che, John H K Yeung. Vasodilatory actions of xanthones isolated from a Tibetan herb, Halenia elliptica. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2009 Dec; 16(12):1144-50. doi: 10.1016/j.phymed.2009.03.015. [PMID: 19403292]
  • Jin Zhang, Mi-Jeong Ahn, Qi Shi Sun, Ki-Yoon Kim, Yun Ha Hwang, Jei Man Ryu, Jinwoong Kim. Inhibitors of bone resorption from Halenia corniculata. Archives of pharmacal research. 2008 Jul; 31(7):850-5. doi: 10.1007/s12272-001-1237-y. [PMID: 18704326]
  • Yan Wang, Jian-Gong Shi, Mu-Zou Wang, Chun-Tao Che, John H K Yeung. Mechanisms of the vasorelaxant effect of 1, 5-dihydroxy-2, 3-dimethoxy-xanthone, an active metabolite of 1-hydroxy-2, 3, 5-trimethoxy-xanthone isolated from a Tibetan herb, Halenia elliptica, on rat coronary artery. Life sciences. 2008 Jan; 82(1-2):91-8. doi: 10.1016/j.lfs.2007.10.014. [PMID: 18045622]
  • Rodrigo Cristiano, Moacir G Pizzolatti, Franco Delle Monache, Claudia M Rezende, Alexsandro Branco. Two xanthones from Polygala paniculata and confirmation of the 1-hydroxy-2,3,5-trimethoxy-xanthone at trace level by HRGC-MS. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2003 Jul; 58(7-8):490-4. doi: 10.1515/znc-2003-7-808. [PMID: 12939033]
  • I Agata, H Sekizaki, A Sakushima, S Nishibe, S Hisada, K Kimura. [Studies on the constituents of medicinal plants in Hokkaido. I. On the whole herb of Swertia tetrapetala Pall. (1) (author's transl)]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 1981 Nov; 101(11):1067-71. doi: 10.1248/yakushi1947.101.11_1067. [PMID: 7343662]