2,4,6-trihydroxybenzaldehyde (BioDeep_00000024508)

 

Secondary id: BioDeep_00001871962

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite PANOMIX-Anthocyanidin


代谢物信息卡片


2,4,6-Trihydroxybenzaldehyde

化学式: C7H6O4 (154.0266)
中文名称: 2,4,6-三羟基苯甲醛
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 98.98%

Reviewed

Last reviewed on 2024-09-18.

Cite this Page

2,4,6-trihydroxybenzaldehyde. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/2,4,6-trihydroxybenzaldehyde (retrieved 2024-12-23) (BioDeep RN: BioDeep_00000024508). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=C(C=C(C(=C1O)C=O)O)O
InChI: InChI=1S/C7H6O4/c8-3-5-6(10)1-4(9)2-7(5)11/h1-3,9-11H

描述信息

2,4,6-trihydroxybenzaldehyde is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-1λ⁴-chromen-1-ylium. It is generated by unspecified-gutmicro enzyme via an anthocyanidin-c-ring-fission-pattern3 reaction. This anthocyanidin-c-ring-fission-pattern3 occurs in human gut microbiota.
2,4,6-Trihydroxybenzaldehyde is an orally active NF-?B inhibitor. 2,4,6-Trihydroxybenzaldehyde shows anti-tumor activity, anti-cancer cell proliferative activity and anti-obesity activity.

2,4,6-Trihydroxybenzaldehyde. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=487-70-7 (retrieved 2024-09-18) (CAS RN: 487-70-7). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

同义名列表

4 个代谢物同义名

2,4,6-Trihydroxybenzaldehyde; Phloroglucinol aldehyde; Phloroglucinaldehyde; 2,4,6-Trihydroxybenzaldehyde



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Anna M Amini, Karolin Muzs, Jeremy Pe Spencer, Parveen Yaqoob. Pelargonidin-3-O-glucoside and its metabolites have modest anti-inflammatory effects in human whole blood cultures. Nutrition research (New York, N.Y.). 2017 Oct; 46(?):88-95. doi: 10.1016/j.nutres.2017.09.006. [PMID: 29132841]
  • Kil-Nam Kim, Min-Cheol Kang, Nalae Kang, Seo-Young Kim, Chang-Gu Hyun, Seong Woon Roh, Eun-Yi Ko, Kichul Cho, Won-Kyo Jung, Ginnae Ahn, You-Jin Jeon, Daekyung Kim. 2,4,6-Trihydroxybenzaldehyde, a potential anti-obesity treatment, suppressed adipocyte differentiation in 3T3-L1 cells and fat accumulation induced by high-fat diet in C57BL/6 mice. Environmental toxicology and pharmacology. 2015 Mar; 39(2):962-8. doi: 10.1016/j.etap.2015.02.007. [PMID: 25812771]
  • Yaoyao Jia, Minh Hien Hoang, Hee-Jin Jun, Ji Hae Lee, Sung-Joon Lee. Cyanidin, a natural flavonoid, is an agonistic ligand for liver X receptor alpha and beta and reduces cellular lipid accumulation in macrophages and hepatocytes. Bioorganic & medicinal chemistry letters. 2013 Jul; 23(14):4185-90. doi: 10.1016/j.bmcl.2013.05.030. [PMID: 23769638]
  • Christopher Kropat, Dolores Mueller, Ute Boettler, Kristin Zimmermann, Elke H Heiss, Verena M Dirsch, Dorothee Rogoll, Ralph Melcher, Elke Richling, Doris Marko. Modulation of Nrf2-dependent gene transcription by bilberry anthocyanins in vivo. Molecular nutrition & food research. 2013 Mar; 57(3):545-50. doi: 10.1002/mnfr.201200504. [PMID: 23349102]
  • Haiyan Liu, Liwei Gu. Phlorotannins from brown algae (Fucus vesiculosus) inhibited the formation of advanced glycation endproducts by scavenging reactive carbonyls. Journal of agricultural and food chemistry. 2012 Feb; 60(5):1326-34. doi: 10.1021/jf204112f. [PMID: 22248148]
  • Melanie Esselen, Ute Boettler, Nicole Teller, Simone Bachler, Melanie Hutter, Corinna E Rufer, Susanne Skrbek, Doris Marko. Anthocyanin-rich blackberry extract suppresses the DNA-damaging properties of topoisomerase I and II poisons in colon carcinoma cells. Journal of agricultural and food chemistry. 2011 Jul; 59(13):6966-73. doi: 10.1021/jf200379c. [PMID: 21599019]
  • Vanisree Mulabagal, Ruby L Alexander-Lindo, David L Dewitt, Muraleedharan G Nair. Health-Beneficial Phenolic Aldehyde in Antigonon leptopus Tea. Evidence-based complementary and alternative medicine : eCAM. 2011; 2011(?):601249. doi: 10.1093/ecam/nep041. [PMID: 19454555]
  • Beate Fuchs, Rosmarie Süss, Jürgen Schiller. An update of MALDI-TOF mass spectrometry in lipid research. Progress in lipid research. 2011 Jan; 50(1):132. doi: 10.1016/j.plipres.2010.10.001. [PMID: 20937305]
  • Barbara A Nellis, Joe H Satcher, Subhash H Risbud. Phospholipid bilayer formation on a variety of nanoporous oxide and organic xerogel films. Acta biomaterialia. 2011 Jan; 7(1):380-6. doi: 10.1016/j.actbio.2010.07.031. [PMID: 20674809]
  • Sarah C Forester, Andrew L Waterhouse. Identification of Cabernet Sauvignon anthocyanin gut microflora metabolites. Journal of agricultural and food chemistry. 2008 Oct; 56(19):9299-304. doi: 10.1021/jf801309n. [PMID: 18767860]