Mandipropamid (BioDeep_00000002450)
natural product
代谢物信息卡片
Pesticide4_Mandipropamid_C23H22ClNO4_2-(4-Chlorophenyl)-N-{2-[3-methoxy-4-(2-propyn-1-yloxy)phenyl]ethyl}-2-(2-propyn-1-yloxy)acetamide
化学式: C23H22ClNO4 (411.1237282000001)
中文名称: 双炔酰菌胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C#CCOc1ccc(CCNC(=O)C(OCC#C)c2ccc(Cl)cc2)cc1OC
InChI: InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)
描述信息
D016573 - Agrochemicals
D010575 - Pesticides
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3061
同义名列表
数据库引用编号
25 个数据库交叉引用编号
- ChEBI: CHEBI:83617
- KEGG: C18522
- PubChem: 11292824
- Metlin: METLIN72328
- ChEMBL: CHEMBL271907
- CAS: 374726-62-2
- MoNA: CCMSLIB00001058499
- MoNA: CCMSLIB00001058742
- MoNA: CCMSLIB00001058941
- MoNA: EQ306156
- MoNA: EQ306155
- MoNA: EQ306154
- MoNA: EQ306153
- MoNA: EQ306152
- MoNA: EQ306151
- MoNA: EQ306106
- MoNA: EQ306105
- MoNA: EQ306104
- MoNA: EQ306103
- MoNA: EQ306102
- MoNA: EQ306101
- PMhub: MS000002686
- ChEBI: CHEBI:81802
- PubChem: 124489196
- KNApSAcK: 81802
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jing Zhang, Yanhong Li, Yuting Tan, Yu Zhang, Rui Li, Liangliang Zhou, Minghua Wang. The enantioselective environmental fate of mandipropamid in water-sediment microcosms: Distribution, degradation, degradation pathways and toxicity assessment.
The Science of the total environment.
2023 Jun; 891(?):164650. doi:
10.1016/j.scitotenv.2023.164650. [PMID: 37285990] - Zhiguang Hou, Xingang Hou, Liping Wei, Zhanwen Cao, Zhou Lu, Hanju Liu, Zhongbin Lu. Degradation and residues of mandipropamid in soil and ginseng and dietary risk assessment in Chinese culture.
Environmental science and pollution research international.
2023 Feb; 30(10):26367-26374. doi:
10.1007/s11356-022-24024-2. [PMID: 36357760] - Rodger J Belisle, Wei Hao, Nathan Riley, Helga Forster, James Adaskaveg. Root absorption and limited mobility of mandipropamid as compared to oxathiapiprolin and mefenoxam after soil treatment of citrus plants for managing Phytophthora root rot.
Plant disease.
2022 Dec; ?(?):. doi:
10.1094/pdis-07-22-1699-re. [PMID: 36541882] - Michael J Ziegler, Klaus Yserentant, Valentin Dunsing, Volker Middel, Antoni J Gralak, Kaisa Pakari, Jörn Bargstedt, Christoph Kern, Annett Petrich, Salvatore Chiantia, Uwe Strähle, Dirk-Peter Herten, Richard Wombacher. Mandipropamid as a chemical inducer of proximity for in vivo applications.
Nature chemical biology.
2022 01; 18(1):64-69. doi:
10.1038/s41589-021-00922-3. [PMID: 34934192] - Yuan Yuan, Jin Miao. Agrochemical control of gene expression using evolved split RNA polymerase.
PeerJ.
2022; 10(?):e13619. doi:
10.7717/peerj.13619. [PMID: 35729907] - Jing Zhang, Qiqi Wu, Yanru Zhong, Zhen Wang, Zongzhe He, Yanqing Zhang, Minghua Wang. Enantioselective Bioactivity, Toxicity, and Degradation in Vegetables and Soil of Chiral Fungicide Mandipropamid.
Journal of agricultural and food chemistry.
2021 Nov; 69(45):13416-13424. doi:
10.1021/acs.jafc.1c04370. [PMID: 34738463] - Timothy B Siegenthaler, Zachariah R Hansen. Sensitivity of Phytophthora capsici from Tennessee to Mefenoxam, Fluopicolide, Oxathiapiprolin, Dimethomorph, Mandipropamid, and Cyazofamid.
Plant disease.
2021 Oct; 105(10):3000-3007. doi:
10.1094/pdis-08-20-1805-re. [PMID: 33736467] - Silvia L Toffolatti, Giuseppe Russo, Paola Campia, Piero A Bianco, Paolo Borsa, Mauro Coatti, Stefano Ff Torriani, Helge Sierotzki. A time-course investigation of resistance to the carboxylic acid amide mandipropamid in field populations of Plasmopara viticola treated with anti-resistance strategies.
Pest management science.
2018 Dec; 74(12):2822-2834. doi:
10.1002/ps.5072. [PMID: 29749019] - Yigal Cohen, Avia Evgenia Rubin, Mariana Galperin. Oxathiapiprolin-based fungicides provide enhanced control of tomato late blight induced by mefenoxam-insensitive Phytophthora infestans.
PloS one.
2018; 13(9):e0204523. doi:
10.1371/journal.pone.0204523. [PMID: 30260986] - I M Nanni, A Pirondi, N Contaldo, M Collina. Screening of sensitivity to mandipropamid of Plasmopara viticola populations from Italian vineyards by molecular and biological methods.
Letters in applied microbiology.
2016 Oct; 63(4):268-73. doi:
10.1111/lam.12613. [PMID: 27401831] - Waziha Farha, Md Musfiqur Rahman, A M Abd El-Aty, Sung-Woo Kim, Da-I Jung, So Jeong Im, Jeong-Heui Choi, Md Humayun Kabir, Kang-Bong Lee, Ho-Chul Shin, Jae-Han Shim. Analysis of mandipropamid residual levels through systematic method optimization against the matrix complexity of sesame leaves using HPLC/UVD.
Biomedical chromatography : BMC.
2016 Jul; 30(7):990-995. doi:
10.1002/bmc.3638. [PMID: 26491843] - Sang-Youl Park, Francis C Peterson, Assaf Mosquna, Jin Yao, Brian F Volkman, Sean R Cutler. Agrochemical control of plant water use using engineered abscisic acid receptors.
Nature.
2015 Apr; 520(7548):545-8. doi:
10.1038/nature14123. [PMID: 25652827] - Mathias Blum, Ulrich Gisi. Insights into the molecular mechanism of tolerance to carboxylic acid amide (CAA) fungicides in Pythium aphanidermatum.
Pest management science.
2012 Aug; 68(8):1171-83. doi:
10.1002/ps.3279. [PMID: 22431165] - Mathias Blum, Hannes A Gamper, Maya Waldner, Helge Sierotzki, Ulrich Gisi. The cellulose synthase 3 (CesA3) gene of oomycetes: structure, phylogeny and influence on sensitivity to carboxylic acid amide (CAA) fungicides.
Fungal biology.
2012 Apr; 116(4):529-42. doi:
10.1016/j.funbio.2012.02.003. [PMID: 22483051] - Yoshinao Aoki, Seiichi Furuya, Shunji Suzuki. Method for rapid detection of the PvCesA3 gene allele conferring resistance to mandipropamid, a carboxylic acid amide fungicide, in Plasmopara viticola populations.
Pest management science.
2011 Dec; 67(12):1557-61. doi:
10.1002/ps.2214. [PMID: 21674751] - Na Su, Zhen-Jun Wang, Li-Zhong Wang, Xiao Zhang, Wei-Li Dong, Hong-Xue Wang, Zheng-Ming Li, Wei-Guang Zhao. Synthesis and biological evaluation of isosteric analogs of mandipropamid for the control of oomycete pathogens.
Chemical biology & drug design.
2011 Jul; 78(1):101-11. doi:
10.1111/j.1747-0285.2011.01093.x. [PMID: 21457472] - Mathias Blum, Maya Waldner, Ulrich Gisi. A single point mutation in the novel PvCesA3 gene confers resistance to the carboxylic acid amide fungicide mandipropamid in Plasmopara viticola.
Fungal genetics and biology : FG & B.
2010 Jun; 47(6):499-510. doi:
10.1016/j.fgb.2010.02.009. [PMID: 20226261] - Mathias Blum, Martine Boehler, Eva Randall, Vanessa Young, Michael Csukai, Sabrina Kraus, Florence Moulin, Gabriel Scalliet, Anna O Avrova, Stephen C Whisson, Raymonde Fonne-Pfister. Mandipropamid targets the cellulose synthase-like PiCesA3 to inhibit cell wall biosynthesis in the oomycete plant pathogen, Phytophthora infestans.
Molecular plant pathology.
2010 Mar; 11(2):227-43. doi:
10.1111/j.1364-3703.2009.00604.x. [PMID: 20447272]