5alpha,8alpha-Epidioxycholest-6-en-3beta-ol (BioDeep_00000244357)

   

Cytotoxicity


代谢物信息卡片


(-)-5alpha,8alpha-Epidioxycholest-6-en-3beta-ol

化学式: C27H44O3 (416.3290274)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1[C@@]23[C@](CC[C@@H]1O)([C@@H]1[C@](C=C2)([C@H]2[C@](CC1)([C@H](CC2)[C@H](C)CCCC(C)C)C)OO3)C
InChI: InChI=1S/C27H44O3/c1-18(2)7-6-8-19(3)21-9-10-22-24(21,4)13-12-23-25(5)14-11-20(28)17-26(25)15-16-27(22,23)30-29-26/h15-16,18-23,28H,6-14,17H2,1-5H3/t19-,20+,21-,22-,23-,24-,25-,26-,27+/m1/s1

描述信息

A cholestanoid that is cholest-6-ene substituted by a beta-hydroxy group at position 3 and a peroxy group between positions 5 and 8 (the 5alpha,8alpha stereoisomer). Isolated from the sea urchin Diadema setosum, it exhibits cytotoxicity against variuos cancer cell lines.

同义名列表

2 个代谢物同义名

5alpha,8alpha-Epidioxycholest-6-en-3beta-ol; (-)-5alpha,8alpha-Epidioxycholest-6-en-3beta-ol



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

5 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Tian-Peng Yin, Yun Xing, Le Cai, Jing Yu, Ping Luo, Zhong-Tao Ding. A new polyketide glycoside from the rhizospheric Clonostachys rogersoniana associated with Panax notoginseng. Journal of Asian natural products research. 2017 Dec; 19(12):1258-1263. doi: 10.1080/10286020.2017.1314271. [PMID: 28397534]
  • Bai Bai, Yu Chen, Wen-juan Liu, Min Yin, Ming Wang, Xu Feng. [Chemical Constituents of Petroleum Ether Fraction of Lonicera macranthoides Roots]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2015 Mar; 38(3):518-20. doi: ". [PMID: 26495652]
  • Kathryn E Clark, Angela Capper, Gina Della Togna, Valerie J Paul, Luz I Romero, Timothy Johns, Luis Cubilla-Rios, Todd L Capson. Ecology- and bioassay-guided drug discovery for treatments of tropical parasitic disease: 5alpha,8alpha-epidioxycholest-6-en-3beta-ol isolated from the mollusk Dolabrifera dolabrifera shows significant activity against Leishmania donovani. Natural product communications. 2013 Nov; 8(11):1537-40. doi: ". [PMID: 24427935]
  • Yi-Na Wang, Jin-Yan Cai, Lin Zhao, En Zhu, De-Zhi Zhang. [Study on chemical constituents from Anoectochilus chapaensis]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2012 Jun; 35(6):911-3. doi: . [PMID: 23236826]
  • Jianglin Zhao, Yan Mou, Tijiang Shan, Yan Li, Ligang Zhou, Mingan Wang, Jingguo Wang. Antimicrobial metabolites from the endophytic fungus Pichia guilliermondii isolated from Paris polyphylla var. yunnanensis. Molecules (Basel, Switzerland). 2010 Nov; 15(11):7961-70. doi: 10.3390/molecules15117961. [PMID: 21060302]
  • Lu Jia, Dong Li, Lin-lin Jing, Ming-ming Guo. [Studies on the chemical constituents from petroleum ether portion of Abelmoschus esculentus]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2010 Aug; 33(8):1262-5. doi: ". [PMID: 21213539]
  • Jian-Peng Huang, Yang-Min Ma, Jian-Shuang Jiang, Pei-Cheng Zhang. [Studies on constituents from root and stem of Ervatamia hainanensis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2006 Jul; 31(14):1166-8. doi: ". [PMID: 17048586]