2-Biphenylol (BioDeep_00000002400)

 

Secondary id: BioDeep_00001867603

human metabolite Endogenous


代谢物信息卡片


2-phenylphenate tetrahydrate

化学式: C12H10O (170.073161)
中文名称: 2-苯基苯酚
谱图信息: 最多检出来源 Viridiplantae(plant) 0.1%

分子结构信息

SMILES: C1=CC=C(C=C1)C2=CC=CC=C2O
InChI: InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H

描述信息

2-Biphenylol is found in lemon. It is an antifungal agent and preservative. 2-Biphenylol is used for post-harvest control of storage disease in apples, citrus fruit, stone fruit, tomatoes, cucumber and peppers through the use of impregnated wrapping materials or by direct application in a wax. 2-Biphenylol is used in food seasonings. Inhibitory to a wider range of moulds than Biphenyl HMJ12-A. The practical way of treatment is to immerse citrus fruit in an alkaline aqueous solution of the parent compound or its Na salt
Antifungal agent, preservative. It is used for post-harvest control of storage disease in apples, citrus fruit, stone fruit, tomatoes, cucumber and peppers through the use of impregnated wrapping materials or by direct application in a wax. It is used in food seasonings. Inhibitory to a wider range of moulds than Biphenyl HMJ12-A. The practical way of treatment is to immerse citrus fruit in an alkaline aq. soln. of the parent compound or its Na salt. 2-Biphenylol is found in lemon.
CONFIDENCE standard compound; INTERNAL_ID 1392; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9460; ORIGINAL_PRECURSOR_SCAN_NO 9456
CONFIDENCE standard compound; INTERNAL_ID 1392; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9365; ORIGINAL_PRECURSOR_SCAN_NO 9363
CONFIDENCE standard compound; INTERNAL_ID 1392; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9398; ORIGINAL_PRECURSOR_SCAN_NO 9393
CONFIDENCE standard compound; INTERNAL_ID 1392; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9460; ORIGINAL_PRECURSOR_SCAN_NO 9457
CONFIDENCE standard compound; INTERNAL_ID 1392; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9464; ORIGINAL_PRECURSOR_SCAN_NO 9459
CONFIDENCE standard compound; INTERNAL_ID 1392; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9412; ORIGINAL_PRECURSOR_SCAN_NO 9407
CONFIDENCE standard compound; INTERNAL_ID 970; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4368; ORIGINAL_PRECURSOR_SCAN_NO 4365
CONFIDENCE standard compound; INTERNAL_ID 970; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4893; ORIGINAL_PRECURSOR_SCAN_NO 4890
CONFIDENCE standard compound; INTERNAL_ID 970; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4862; ORIGINAL_PRECURSOR_SCAN_NO 4859
CONFIDENCE standard compound; INTERNAL_ID 970; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4365; ORIGINAL_PRECURSOR_SCAN_NO 4361
CONFIDENCE standard compound; INTERNAL_ID 970; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4839; ORIGINAL_PRECURSOR_SCAN_NO 4835
CONFIDENCE standard compound; INTERNAL_ID 970; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4882; ORIGINAL_PRECURSOR_SCAN_NO 4877
D - Dermatologicals > D08 - Antiseptics and disinfectants > D08A - Antiseptics and disinfectants > D08AE - Phenol and derivatives
D009676 - Noxae > D002273 - Carcinogens
D000890 - Anti-Infective Agents
D016573 - Agrochemicals
D004202 - Disinfectants
D010575 - Pesticides

同义名列表

52 个代谢物同义名

2-phenylphenate tetrahydrate; Sodium ortho-phenylphenate; 1-Hydroxy-2-phenylbenzene; Sodium ortho-phenylphenol; 2-Phenylphenol, bsi, iso; Hydroxy-2-phenylbenzene; Sodium O-phenylphenoate; 2-Hydroxy-1,1-biphenyl; 2-Phenylphenol sodium; Orthohydroxydipbenyl; Orthohydroxydiphenyl; Ortho-phenylphenate; (1,1-Biphenyl)-2-ol; [1,1-biphenyl]-2-ol; 2-Hydroxy biphenyl; Orthophenyl phenol; ortho-Phenylphenol; 1,1-Biphenyl-2-ol; 2-Hydroxybiphenyl; O-Hydroxybiphenyl; O-Hydroxydiphenyl; Orthophenylphenol; 2-Hydroxydiphenyl; O-Phenyl phenol; Hydroxybiphenyl; O-Phenylphenate; 2-Phenylphenol; O-Phenylphenol; Hydroxdiphenyl; Nipacide OPP; O-Diphenylol; O-Biphenylol; 2-Biphenylol; Phenylphenol; 2-Fenylfenol; Stellisept; Dowicide 1; Biphenylol; Orthoxenol; FEMA 3959; Rotoline; Manusept; Dowicide; Lyorthol; O-Xonal; O-Xenol; Torsite; Nectryl; Amocid; OPP?; e231; HBP



数据库引用编号

30 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

6 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(4)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

5 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Nasreen Nazar, Ajeeshkumar Kizhakkeppurath Kumaran, A S Athira, Megha Sivadas, Satyen Kumar Panda, Kaushik Banerjee, Niladri Sekhar Chatterjee. Untargeted metabolomics reveals potential health risks associated with chronic exposure to environmentally relevant concentrations of 2-Phenylphenol. The Science of the total environment. 2024 Feb; 912(?):169172. doi: 10.1016/j.scitotenv.2023.169172. [PMID: 38101641]
  • René Bérubé, Patrick Bélanger, Jean-François Bienvenu, Pierre Dumas, Gilles Provencher, Éric Gaudreau, Normand Fleury. New approach for the determination of ortho-phenylphenol exposure by measurement of sulfate and glucuronide conjugates in urine using liquid chromatography-tandem mass spectrometry. Analytical and bioanalytical chemistry. 2018 Nov; 410(28):7275-7284. doi: 10.1007/s00216-018-1339-5. [PMID: 30229309]
  • Chiara Perruchon, Sotirios Vasileiadis, Constantina Rousidou, Evangelia S Papadopoulou, Georgia Tanou, Martina Samiotaki, Constantinos Garagounis, Athanasios Molassiotis, Kalliope K Papadopoulou, Dimitrios G Karpouzas. Metabolic pathway and cell adaptation mechanisms revealed through genomic, proteomic and transcription analysis of a Sphingomonas haloaromaticamans strain degrading ortho-phenylphenol. Scientific reports. 2017 07; 7(1):6449. doi: 10.1038/s41598-017-06727-6. [PMID: 28743883]
  • Emma Nixon, James D Brooks, Patricia A Routh, Jason T Chittenden, Ronald E Baynes. Pharmacokinetics of 14 C-ortho-phenylphenol following intravenous administration in pigs. Journal of applied toxicology : JAT. 2017 04; 37(4):508-512. doi: 10.1002/jat.3380. [PMID: 27593710]
  • S Balakrishnan, L Hasegawa, D A Eastmond. The role of urinary pH in o-phenylphenol-induced cytotoxicity and chromosomal damage in the bladders of F344 rats. Environmental and molecular mutagenesis. 2016 Apr; 57(3):210-9. doi: 10.1002/em.22002. [PMID: 26919225]
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  • Ceri Lewis, Siham Beggah, Chris Pook, Carlos Guitart, Clare Redshaw, Jan Roelof van der Meer, James W Readman, Tamara Galloway. Novel use of a whole cell E. coli bioreporter as a urinary exposure biomarker. Environmental science & technology. 2009 Jan; 43(2):423-8. doi: 10.1021/es801325u. [PMID: 19238974]
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  • Martin B Oleksiewicz, Jennifer Southgate, Lars Iversen, Frederikke L Egerod. Rat Urinary Bladder Carcinogenesis by Dual-Acting PPARalpha + gamma Agonists. PPAR research. 2008; 2008(?):103167. doi: 10.1155/2008/103167. [PMID: 19197366]
  • Olivier Mazéas, Hélène Budzinski. Solid-phase extraction and purification for the quantification of polycyclic aromatic hydrocarbon metabolites in fish bile. Analytical and bioanalytical chemistry. 2005 Nov; 383(6):985-90. doi: 10.1007/s00216-005-0096-4. [PMID: 16244859]
  • Richard A Fenske, Asa Bradman, Robin M Whyatt, Mary S Wolff, Dana B Barr. Lessons learned for the assessment of children's pesticide exposure: critical sampling and analytical issues for future studies. Environmental health perspectives. 2005 Oct; 113(10):1455-62. doi: 10.1289/ehp.7674. [PMID: 16203262]
  • Xiaoyun Ye, Zsuzsanna Kuklenyik, Larry L Needham, Antonia M Calafat. Automated on-line column-switching HPLC-MS/MS method with peak focusing for the determination of nine environmental phenols in urine. Analytical chemistry. 2005 Aug; 77(16):5407-13. doi: 10.1021/ac050390d. [PMID: 16097788]
  • Roberto Bravo, Lisa M Caltabiano, Carolina Fernandez, Kimberly D Smith, Maribel Gallegos, Ralph D Whitehead, Gayanga Weerasekera, Paula Restrepo, Amanda M Bishop, José J Perez, Larry L Needham, Dana B Barr. Quantification of phenolic metabolites of environmental chemicals in human urine using gas chromatography-tandem mass spectrometry and isotope dilution quantification. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2005 Jun; 820(2):229-36. doi: 10.1016/j.jchromb.2005.03.012. [PMID: 15899376]
  • K Vengatajalabathy Gobi, Hiroyuki Tanaka, Yukihiro Shoyama, Norio Miura. Continuous flow immunosensor for highly selective and real-time detection of sub-ppb levels of 2-hydroxybiphenyl by using surface plasmon resonance imaging. Biosensors & bioelectronics. 2004 Sep; 20(2):350-7. doi: 10.1016/j.bios.2004.02.003. [PMID: 15308241]
  • Asa Bradman, Dana B Barr, Birgit G Claus Henn, Timothy Drumheller, Cynthia Curry, Brenda Eskenazi. Measurement of pesticides and other toxicants in amniotic fluid as a potential biomarker of prenatal exposure: a validation study. Environmental health perspectives. 2003 Nov; 111(14):1779-82. doi: 10.1289/ehp.6259. [PMID: 14594631]
  • Norio Miura, Makoto Sasaki, K Vengatajalabathy Gobi, Chiwa Kataoka, Yukihiro Shoyama. Highly sensitive and selective surface plasmon resonance sensor for detection of sub-ppb levels of benzo[a]pyrene by indirect competitive immunoreaction method. Biosensors & bioelectronics. 2003 Jul; 18(7):953-9. doi: 10.1016/s0956-5663(02)00242-7. [PMID: 12713919]
  • Tomoko Okubo, Itsu Kano. [Studies on estrogenic activities of food additives with human breast cancer MCF-7 cells and mechanism of estrogenicity by BHA and OPP]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2003 Jun; 123(6):443-52. doi: 10.1248/yakushi.123.443. [PMID: 12822488]
  • Robin M Whyatt, Dana B Barr, David E Camann, Patrick L Kinney, John R Barr, Howard F Andrews, Lori A Hoepner, Robin Garfinkel, Yair Hazi, Andria Reyes, Judyth Ramirez, Yesenia Cosme, Frederica P Perera. Contemporary-use pesticides in personal air samples during pregnancy and blood samples at delivery among urban minority mothers and newborns. Environmental health perspectives. 2003 May; 111(5):749-56. doi: 10.1289/ehp.5768. [PMID: 12727605]
  • Jian-Ying Hu, Takako Aizawa. Quantitative structure-activity relationships for estrogen receptor binding affinity of phenolic chemicals. Water research. 2003 Mar; 37(6):1213-22. doi: 10.1016/s0043-1354(02)00378-0. [PMID: 12598185]
  • Rafael Rodríguez, Jordi Mañes, Yolanda Picó. Off-line solid-phase microextraction and capillary electrophoresis mass spectrometry to determine acidic pesticides in fruits. Analytical chemistry. 2003 Feb; 75(3):452-9. doi: 10.1021/ac025884e. [PMID: 12585470]
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